Presenilins are not required for Aβ42 production in the early secretory pathway

Nature Neuroscience

Volumn 5, Issue 9, 2002, Pages 849-855

  Wilson, Christina A ^a   Doms, Robert W ^a   Zheng, Hui ^b,c   Lee, Virginia M Y ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; CELL PROTEIN; PRESENILIN 1; PRESENILIN 2;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; BREFELDIN A; CELL COMPARTMENTATION; CELLS, CULTURED; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; FEMALE; FETUS; HUMANS; MALE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; NEURONS; PEPTIDE FRAGMENTS; PREGNANCY; PRESENILIN-1; PRESENILIN-2; PROTEIN SYNTHESIS INHIBITORS; STEM CELLS;

EID: 0036727463     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn898     Document Type: Article

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