PTH induction of transcriptional activity of the cAMP response element-binding protein requires the serine 129 site and glycogen synthase kinase-3 activity, but not casein kinase II sites

Endocrinology

Volumn 143, Issue 2, 2002, Pages 674-682

  Tyson, Darren R ^a,b,c   Swarthout, John T ^a,b   Jefcoat, Stephen C ^a,b   Partridge, Nicola C ^a,b  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CASEIN KINASE II; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPITOPE; GENISTEIN; GLYCOGEN SYNTHASE KINASE 3; LITHIUM CHLORIDE; PARATHYROID HORMONE; PROTEIN C FOS; SERINE;

ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; MUTATIONAL ANALYSIS; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

EID: 0036157857     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.143.2.8626     Document Type: Article

References (44)

1. The CREB family of transcription activators
2. Transcriptional regulation by CREB and its relatives
3. The CREB/ATF family of transcription factors: Modulation by reversible phosphorylation
4. Signal transduction and gene control: The cAMP pathway
5. Signal transduction and gene regulation: The nuclear response to cAMP
6. Signal transduction through the cAMP-dependent protein kinase
7. Transcriptional regulation by cyclic AMP
8. CREB: A stimulus-induced transcription factor activated by a diverse array of extracellular signals
9. Parathyroid hormone induces c-fos promoter activity in osteoblastic cells through phosphorylated cAMP response element (CRE)-binding protein binding to the major CRE
10. Increased osteoblastic c-fos expression by parathyroid hormone requires protein kinase A phosphorylation of the cyclic adenosine 3′,5′-monophosphate response element-binding protein at serine 133
11. Parathyroid hormone induces c-fos and c-jun messenger RNA in rat osteoblastic cells
12. Virus induction of osteosarcomas in mice
13. Candidate product of the FBJ murine osteosarcoma virus oncogene: Characterization of a 55,000-dalton phosphoprotein
14. Expression of the c-fos proto-oncogene in bone, cartilage and tooth forming tissues during mouse development
15. Osteoblasts are target cells for transformation in c-fos transgenic mice
16. Pleiotropic effects of a null mutation in the c-fos proto-oncogene
17. Sequential analysis of gene expression after an osteogenic stimulus: c-fos expression is induced in osteocytes
18. Parathyroid hormone regulates the rat collagenase-3 promoter in osteoblastic cells through the cooperative interaction of the activator protein-1 site and the runt domain binding sequence
19. Regulation of CREB phosphorylation in the suprachiasmatic nucleus by light and a circadian clock
20. CREB: A mediator of long-term memory from mollusks to mammals
21. CREB and memory
22. cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates δ-CREB, and a synthetic δ-CREB peptide
23. Phosphoserine as a recognition determinant for glycogen synthase kinase-3: Phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1
24. Multiple and cooperative phosphorylation events regulate the CREM activator function
25. A secondary phosphorylation of CREB341 at Ser129 is required for the cAMP-mediated control of gene expression. A role for glycogen synthase kinase-3 in the control of gene expression
26. Heterodimerization of c-Jun with ATF-2 and c-Fos is required for positive and negative regulation of the human urokinase enhancer
27. CREB: A Ca(2+)-regulated transcription factor phosphorylated by calmodulin-dependent kinases
28. Identification of a specific receptor for interstitial collagenase on osteoblastic cells
29. Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3
30. Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation
31. Isoform differences in substrate recognition by glycogen synthase kinases 3α and 3β in the phosphorylation of phosphatase inhibitor 2
32. Tyrosine dephosphorylation and concurrent inactivation of protein kinase FA/GSK-3α by genistein in A431 cells
33. Glycogen synthase kinase-3: Functions in oncogenesis and development
34. Activation of the Wnt signaling pathway: A molecular mechanism for lithium action
35. Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells
36. Specificity and mechanism of action of some commonly used protein kinase inhibitors
37. A molecular mechanism for the effect of lithium on development
38. PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line
39. 2, and prostacyclin
40. Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits
41. Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
42. Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene
43. Cell-cycle-regulated phosphorylation of cAMP response element-binding protein: Identification of novel phosphorylation sites
44. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity