Intracellular generation and accumulation of amyloid β-peptide terminating at amino acid 42

Journal of Biological Chemistry

Volumn 272, Issue 26, 1997, Pages 16085-16088

  Wild Bode, Christine ^a   Yamazaki, Tsuneo ^b   Capell, Anja ^a   Leimer, Uwe ^a   Steiner, Harald ^a   Ihara, Yasuo ^b   Haass, Christian ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BREFELDIN A; GAMMA SECRETASE; MONENSIN; UNCLASSIFIED DRUG;

ACIDIFICATION; ALZHEIMER DISEASE; AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ARTICLE; CELL FRACTIONATION; ENDOPLASMIC RETICULUM; GENETIC HETEROGENEITY; HUMAN; HUMAN CELL; PEPTIDE ANALYSIS; PRIORITY JOURNAL;

AMYLOID BETA-PROTEIN; BREFELDIN A; CELL LINE; CYCLOPENTANES; ENDOPLASMIC RETICULUM; HUMANS; KIDNEY;

EID: 0030952217     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.26.16085     Document Type: Article

References (33)

1. Cotman, C. W., and Pike, C. J. (1994) in Alzheimer's Disease (Terry, R. D., Katzman, R., and Bick, K., eds) pp. 305-315, Raven Press, New York
2. Cummings, B. J., and Cotman, C. W. (1995) Lancet 346, 1524-1528
3. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-18298
4. Saido, T. C., Iwatsubo, T., Mann, D. M., Shimada, H., Ihara, Y., Kawashima, S. (1995) Neuron 14, 457-466
5. Kuo, Y.-M., Emmerling, M. R., Vigo-Pelfrey, C., Kasunic, T. C., Kirkpatrick, J. B., Murdoch, G. H., Ball, M. J., and Roher, A. E. (1996) J. Biol. Chem. 271, 4077-4081
6. Pike, C. J., Overman, M. J., and Cotman, C. W. (1995) J. Biol. Chem. 270, 23895-23898
7. Haass, C., Schlossmacher, M. G., Hung, A. Y., Vigo-Pelfrey, C., Mellon, A., Ostaszewski, B. L., Lieberburg, I., Koo, E. H., Schenk, D., Teplow, D. B., and Selkoe, D. J. (1992) Nature 359, 322-325
8. Haass, C., Hung, A. Y., Schlossmacher, M. G., Teplow, D. B., and Selkoe, D. J. (1993) J. Biol. Chem. 268, 3021-3024
9. Haass, C., Hung, A. Y., Selkoe, D. J., and Teplow, D. B. (1994) J. Biol. Chem. 269, 17741-17748
10. Haass, C., Capell, A., Citron, M., Teplow, D. B., and Selkoe, D. J. (1995) J. Biol. Chem. 270, 6186-6192
11. Capell, A., Teplow, D. B., Citron, M., Selkoe, D. J., and Haass, C. (1996) Amyloid 3, 150-155
12. Suzuki, N., Cheung, T. T., Cai, X. D., Odaka, A., Otvos, L. jr., Eckman, C., Golde, T. E., and Younkin, S. G. (1994) Science 264, 1336-1340
13. Younkin S. (1995) Ann. Neurol. 37, 287-288
14. Tanzi, R., Kovacs, D., Kim, T.-W., Moir, R., Guenette, S., and Wasco, W. (1996) Neurobiol. Dis. 3, 159-168
15. Haass, C. (1997) Neuron 18, 687-690
16. Scheuner, D., Eckman, C., Jensen, M., Song, X., Citron, M., Suzuki, N., Bird, T. D., Hardy, J., Hutton, M., Kukull, W., Larson, E., Levy-Lahad, E., Viitanen, M., Peskind, E., Poorkaj, P., Schellenberg, G., Tanzi, R., Wasco, W., Lannfelt, L., Selkoe, D., and Younkin, S. (1996) Nat. Med. 2, 864-870
17. Mann, D., Iwatsubo, T., Cairns, N., Lantos, P., Nochlin, D., Sumi, S., Bird, T., Poorkaj, P., Hardy, J., Hutton, M., Prihar, G., Crook, R., Rossor, N., and Haltia, M. (1996) Ann. Neurol. 40, 149-156
18. Lemere, C., Lopera, F., Kosik, K., Lendon, C., Ossa, J., Saido, T., Yamaguchi, H., Ruiz, A., Martinez, A., Madrigal, L., Hincapie, L., Arango, J., Anthony, D., Koo, H., Goate, A., Selkoe, D., and Arango, J. (1996) Nat. Med. 2, 1146-1150
19. Koo, E. H., and Squazzo, S. L. (1994) J. Biol. Chem. 269, 17386-17389
20. Weidemann, A., König, G., Bunke, D., Fischer, P., Salbaum, M., Masters, C. L., and Beyreuther, K. (1989) Cell 57, 115-126
21. Gabuzda, D., Busciglio, J., Chen, L. B., Matsudaira, P., and Yankner, B. A. (1994) J. Biol. Chem. 269, 13623-13628
22. Shinkai, Y., Yoshimura, M., Ito, Y., Odaka, A., Suzuki, N., Yanagisawa, Y., and Ihara, Y. (1995) Ann. Neurol. 38, 421-428
23. Yamatsuji, T., Matsui, T., Okamoto, T., Komatsuzaki, K., Takeda, S., Fukumoto, H., Iwatsubo, T., Suzuki, N., Asami-Odaka, A., Ireland, S., Kinane, B., Giambarella, U., and Nishimoto I. (1996) Science 272, 1349-1352
24. Leimer, U., Franke, W., and Leube, R. (1996) Exp. Cell Res. 224, 88-95
25. Busciglio, J., Gabuzda, D. H., Matsudaira, P., and Yankner, B. A. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2092-2096
26. Citron, M., Diehl, T., Gordon, G., Biere, A., Seubert, P., and Selkoe, D. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13170-13175
27. Klafki, H.-W., Abramowski, D., Swoboda, R., Paganetti, P., and Staufenbiel, M. (1996) J. Biol. Chem. 271, 28655-28659
28. Tischer, E., and Cordell, B. (1996) J. Biol. Chem. 271, 21914-21919
29. Kovacs, D. M., Fausett, H. J., Page, K. J., Kim, T. W., Moir, R. D., Merriam, D. E., Hollister, R. D., Hallmark, O. G., Mancini, R., Felsenstein, K. M., Hyman, B. T., Tanzi, R. E., and Wasco, W. (1996) Nat. Med. 2, 224-229
30. Cook, D. G., Sung, J. C., Golde, T. E., Felsenstein, K. M., Wojczyk, B. S., Tanzi, R. E., Trojanowski, J. Q., Lee, V., and Doms, R. W. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 9223-9228
31. Walter, J., Capell, A., Grünberg, J., Pesold, B., Schindzielorz, A., Prior, R., Podlisny, M. B., Fraser, P., St. George-Hyslop, P., Selkoe, D. J., and Haass, C. (1996) Mol. Med. 2, 673-691
32. De Strooper, B., Beullens, M., Contreras, B., Levesque, L., Craessaerts, K., Cordell, B., Moechars, D., Bollen, M., Fraser, P., St. George-Hyslop, P., and Van Leuven, F. (1997) J. Biol. Chem. 272, 3590-3598
33. Masliah, E., Sisk, A., Mallory, M., Mucke, L., Schenk, D., and Games, D. (1996) J. Neurosci. 16, 5795-5811