Accumulation and Aggregation of Amyloid β-Protein in Late Endosomes of Niemann-Pick Type C Cells

Journal of Biological Chemistry

Volumn 276, Issue 6, 2001, Pages 4454-4460

  Yamazaki, Tsuneo ^a   Chang, Ta Yuan ^b   Haass, Christian ^c   Ihara, Yasuo ^a,d  

^a UNIVERSITY OF TOKYO   (Japan)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MUNICH   (Germany)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; BRAIN; CELLS; CHOLESTEROL; DISEASES; METABOLISM;

PRECISE CELLULAR LINKAGE;

PROTEINS;

3BETA (2 DIETHYLAMINOETHOXY)ANDROST 5 EN 17 ONE; AMYLOID BETA PROTEIN; 3 BETA (2 (DIETHYLAMINO)ETHOXY)ANDROST 5 EN 17 ONE; 3-BETA-(2-(DIETHYLAMINO)ETHOXY)ANDROST-5-EN-17-ONE; ANDROSTANE DERIVATIVE; CHOLESTEROL; HYPOCHOLESTEROLEMIC AGENT;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL FRACTIONATION; CELL LEVEL; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DESMOSOME; DISEASE PREDISPOSITION; ENDOSOME; FLOW CYTOMETRY; HUMAN; HUMAN CELL; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN INTERACTION; PROTEIN METABOLISM; PROTEIN SECRETION; WESTERN BLOTTING; ANIMAL; CHO CELL; ENDOCYTOSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HAMSTER; METABOLISM; PATHOLOGY;

ANIMALIA;

AMYLOID BETA-PROTEIN; ANDROSTENES; ANIMALS; ANTICHOLESTEREMIC AGENTS; CHO CELLS; CHOLESTEROL; CRICETINAE; ENDOCYTOSIS; ENDOSOMES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMANS; NIEMANN-PICK DISEASES;

EID: 0035830844     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M009598200     Document Type: Article

References (44)

1. Selkoe, D. J. (1999) Nature 399, (suppl.) 23A-31A
2. Iwatsubo, T., Odaka, A., Suzuki, N., Mizusawa, H., Nukina, N., and Ihara, Y. (1994) Neuron 13, 45-53
3. Iwatsubo, T., Mann, D. M., Odaka, A., Suzuki, N., and Ihara, Y. (1995) Ann. Neurol. 37, 294-299
4. Xu, H., Gouras, G. K., Greenfield, J. P., Vincent, B., Naslund, J., Mazzarelli, L., Fried, G., Jovanovic, J. N., Seeger, M., Relkin, N. R., Liao, F., Checler, F., Buxbaum, J. D., Chait, B. T., Thinakaran, G., Sisodia, S. S., Wang, R., Greengard, P., and Gandy S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3748-3752
5. Bodovitz, S., and Klein, W. L. (1996) J. Biol. Chem. 271, 4436-4440
6. Howland, D. S., Trusko, S. P., Savage, M. J., Reaume, A. G., Lang D. M., Hirsch, J. D., Maeda, N., Siman, R., Greenberg, B. D., Scott, R. W., and Flood, D. G. (1998) J. Biol. Chem. 273, 16576-16582
7. Kuo, Y.-M., Emmerling, M. R., Bisgaier, C. L., Essenburg, A. D., Lampert, H. C., Drumm, D., and Roher, A. E. (1998) Biochem. Biophys. Res. Commun. 252, 711-715
8. Avdulov, N. A., Chochina, S. V., Igbavboa, U., Warden, C. S., Vassiliev, A. V., and Wood, W. G. (1997) J. Neurochem. 69, 1746-1752
9. Lee, S. J., Liyanage, U., Bickel, P. E., Xia, W., Lansbury, P. T., Jr., and Kosik, K. S. (1998) Nat. Med. 4, 730-734
10. Morishima-Kawashima, M., and Ihara, Y. (1998) Biochemistry 37, 15247-15253
11. Strittmatter, W. J., Saunders, A. M., Schmechel, D., Pericak-Vance, M., Enghild, J., Salvesen, G. S., and Roses, A. D. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 1977-1981
12. Refolo, L. M., Pappolla, M. A., Malester, B., LaFrancois, J., Bryant-Thomas, T., Wang, R., Tint G. S., Sambamurti, K., and Duff, K. (2000) Neurobiol. Dis. 7, 321-331
13. Pentchev, P. G., Vanier, M. T., Suzuki, K., and Patterson, M. C. (1995) in The Metabolic and Molecular Basis of Inherited Disease (Scriver, C. R., Beaudet, W. S., and Sly, J., eds) pp. 2625-2639, McGraw-Hill Inc., New York
14. Kobayashi, T., Beuchat, M. H., Lindsay, M., Frias, S., Palmiter, R. D., Sakuraba, H., Parton, R. G., and Gruenberg, J. (1999) Nat. Cell Biol. 1, 113-118
15. Carstea, E. D., Morris, J. A., Coleman, K. G., Loftus, S. K., Zhang, D., Cummings, C., Gu, J., Rosenfeld, M. A., Pavan, W. J., Krizman, D. B., Nagle, J., Polymeropoulos, M. H., Sturley, S. L., Ioannou, Y. A., Higgins, M. E., Comly, M., Cooney, A., Brown, A., Kaneski, C. R., Blanchette-Mackie, E. J., Dwyer, N. K., Neufeld, E. B., Chang, T. Y., Liscum, L., Strauss, J. F., III, Ohono, K., Zeigler, M., Carmi, R., Sokol, J., Markie, D., O'Neill, R. R., Van Diggelen, O. P., Ellender, M., Patterson, M. C., Brady, R. O., Vanier, M. T., Pentchev, P. G., and Tagle, D. A. (1997) Science 277, 228-231
16. Loftus, S. K., Morris, J. A., Carstea, E. D., Gu, J. Z., Cummings, C., Brown, A., Ellison, J., Ohno, K., Rosenfeld, M. A., Tagle, D. A., Pentchev, P. G., and Pavan, W. J. (1997) Science 277, 232-235
17. Lange, Y., and Steck, T. L. (1994) J. Biol. Chem. 269, 29371-29374
18. Lange, Y., Ye, J., Rigney, M., and Steck, T. (2000) J. Biol. Chem. 275, 17468-17475
19. Cruz, J. C., Sugii, S., Yu, C., and Chang, T. Y. (2000) J. Biol. Chem. 275, 4013-4021
20. Koo, E. H., and Squazzo, S. L. (1994) J. Biol. Chem. 269, 17386-17389
21. Haass, C., Koo, E. H., Mellon, A., Hung, A. Y., and Selkoe, D. J. (1992) Nature 357, 500-503
22. Cadigan, K. M., Spillane, D. M., and Chang, T. Y. (1990) J. Cell Biol. 110, 295-308
23. Niwa, H., Yamamura, K., and Miyazaki, J. (1991) Gene (Amst.) 108, 193-199
24. Lange, Y., Ye, J., and Chin, J. (1997) J. Biol. Chem. 272, 17018-17022
25. van der Goot, F. G. (1997) Electrophoresis 18, 2689-2693
26. Enya, M., Morishima-Kawashima, M., Yoshimura, M., Shinkai, Y., Kusui, K., Khan, K., Games, D., Schenk, D., Sugihara, S., Yamaguchi, H., and Ihara, Y. (1999) Am. J. Pathol. 154, 271-279
27. Yanagisawa, K., Odaka, A., Suzuki, N., and Ihara, Y. (1995) Nat. Med. 1, 1062-1066
28. Kobayashi, T., Stang, E., Fang, K. S., de Moerloose, P., Parton, R. G., and Gruenberg, J. (1998) Nature 392, 193-197
29. Shinkai, Y., Yoshimura, M., Ito, Y., Odaka, A., Suzuki, N., Yanagisawa, K., and Ihara, Y. (1995) Ann. Neurol. 38, 421-428
30. Umeda, M., Igarashi, K., Nam, K. S., and Inoue, K. (1989) J. Immunol. 143, 2273-2279
31. Sawamura, N., Morishima-Kawashima, M., Waki, H., Kobayashi, K., Kuramochi, T., Frosch, M. P., Ding, K., Ito, M., Kim, T. W., Tanzi, R. E., Ando, S., and Ihara, Y. (2000) J. Biol. Chem. 275, 27901-27908
32. Chyung, A. S. C., Greenberg, B. D., Cook, D. G., Doms, R. W., and Lee, V. M. (1997) J. Cell Biol. 138, 671-680
33. Meresse, S., Andre, P., Mishal, Z., Barad, M., Brun, N., Desjardins, M., and Gorvel, J. P. (1997) Electrophoresis 18, 2682-2688
34. Sokol, J., Blanchette-Mackie, J., Kruth, H. S., Dwyer, N. K., Amende, L. M., Butler, J. D., Robinson, E., Patel, S., Brady, R. O., and Comly, M. E. (1988) J. Biol. Chem. 263, 3411-3417
35. Härmälä, A. S., Pörn, M. I., Mattjus, P., and Slotte, J. P. (1994) Biochim. Biophys. Acta 1211, 317-325
36. Liscum, L., and Faust, J. R. (1989) J. Biol. Chem. 264, 11796-11806
37. Skovronsky, D. M., Doms, R. W., and Lee, V. M. (1998) J. Cell Biol. 141, 1031-1039
38. Perez, R. G., Soriano, S., Hayes, J. D., Ostaszewski, B., Xia, W., Selkoe, D. J., Chen, X., Stokin, G. B., and Koo, E. H. (1999) J. Biol. Chem. 274, 18851-18856
39. Puri, V., Watanabe R., Dominguez, M., Sun, X., Wheatley, C. L., Marks, D. L., and Pagano, R. E. (1999) Nat. Cell Biol. 1, 386-388
40. Liscum, L., and Klansek, J. J. (1998) Curr. Opin. Lipidol. 9, 131-135
41. Furuichi, T., Aikawa, K., Arai, H., and Inoue, K. (1993) J. Biol. Chem. 268, 27345-27348
42. Jarrett, J. T., and Lansbury, P. T. Jr. (1993) Cell 73, 1055-1058
43. Walsh, D. M., Tseng, B. P., Rydel, R. E., Podlisny, M. B., and Selkoe, D. J. (2000) Biochemistry 39, 10831-10839
44. Vanier, M. T., and Suzuki, K. (1998) Brain Pathol. 8, 163-174