Behavioral phenotyping of GFAP-ApoE3 and -ApoE4 transgenic mice: ApoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

Experimental Neurology

Volumn 170, Issue 2, 2001, Pages 326-344

  Hartman, R E ^a,b   Wozniak, D F ^a,b   Nardi, A ^a   Olney, J W ^a   Sartorius, L ^a   Holtzman, D M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Apolipoprotein E; Emotionality; Knockout mice; Reference memory; Sensorimotor; Spatial learning and memory

Indexed keywords

APOLIPOPROTEIN E; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; GLIAL FIBRILLARY ACIDIC PROTEIN;

ALZHEIMER DISEASE; AMNESIA; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; COGNITION; CONTROLLED STUDY; EMOTIONALITY; HIPPOCAMPUS; INFORMATION PROCESSING; KNOCKOUT MOUSE; LEARNING; LOCOMOTION; MALE; MAZE TEST; MOUSE; NEOCORTEX; NEUROPATHOLOGY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SENSORIMOTOR FUNCTION; SYNAPSE; TASK PERFORMANCE; TRANSGENIC MOUSE; WESTERN BLOTTING; WORKING MEMORY;

EID: 0034870449     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.2001.7715     Document Type: Article

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