Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

Nature Neuroscience

Volumn 4, Issue 3, 2001, Pages 231-232

  Luo, Yi ^a   Bolon, Brad ^a   Kahn, Steve ^a   Bennett, Brian D ^a   Babu Khan, Safura ^a   Denis, Paul ^a   Fan, Wei ^a   Kha, Hue ^a   Zhang, Jianhua ^a   Gong, Yunhua ^a   Martin, Laura ^a   Louis, Jean Claude ^a   Yan, Qiao ^a   Richards, William G ^a   Citron, Martin ^a   Vassar, Robert ^b  

^a AMGEN INC   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; BETA SITE APP CLEAVING ENZYME 1; EOSIN; GAMMA SECRETASE; HEMATOXYLIN; PROTEIN BACE1; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; CENTRAL NERVOUS SYSTEM; ENDOPEPTIDASES; MICE; MICE, KNOCKOUT; PERIPHERAL NERVOUS SYSTEM; PHENOTYPE; SENILE PLAQUES;

EID: 0035116273     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/85059     Document Type: Article

References (15)