Muscarinic agonists reduce tau phosphorylation in non-neuronal cells via GSK-3β inhibition and in neurons

Journal of Neural Transmission

Volumn 107, Issue 10, 2000, Pages 1201-1212

  Forlenza, O V ^a   Spink, J M ^b   Dayanandan, R ^b   Anderton, B H ^b   Olesen, O F ^c   Lovestone, S ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c H LUNDBECK A S   (Denmark)

Author keywords

Acetylcholine; Alzheimer's disease; Glycogen synthase kinase 3; Muscarinic receptor; Tau

Indexed keywords

ALPHA SECRETASE; AMYLOID PRECURSOR PROTEIN; CARBACHOL; GLYCOGEN SYNTHASE KINASE 3BETA; MUSCARINIC AGENT; MUSCARINIC M1 RECEPTOR; MUSCARINIC RECEPTOR; PEPTIDE DERIVATIVE; PROTEIN KINASE C; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; EMBRYO; ENZYME DEGRADATION; ENZYME INHIBITION; MICROTUBULE; NERVE CELL; NEUROFIBRILLARY TANGLE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; RAT;

ACETYLCHOLINE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BINDING SITES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARBACHOL; CELLS, CULTURED; FETUS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASES; LITHIUM CHLORIDE; MICROTUBULES; MUSCARINIC AGONISTS; NEURONS; PHOSPHORYLATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, MUSCARINIC; TAU PROTEINS; TETRAZOLES; THIADIAZOLES;

EID: 0033781487     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020070034     Document Type: Article

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