Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of β-catenin phosphorylation

European Journal of Biochemistry

Volumn 268, Issue 10, 2001, Pages 3036-3041

  Kawamura, Yuuki ^a,b   Kikuchi, Akira ^c   Takada, Ritsuko ^b   Takada, Shinji ^b,d   Sudoh, Shinji ^e   Shibamoto, Sayumi ^f   Yanagisawa, Katsuhiko ^a   Komano, Hiroto ^a  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c HIROSHIMA UNIV SCHOOL OF MEDICINE   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f SETSUNAN UNIVERSITY   (Japan)

Author keywords

catenin; Alzheimer's disease; Presenilin 1; Wnt signaling

Indexed keywords

BETA CATENIN; CYCLOHEXIMIDE; LACTACYSTIN; PRESENILIN 1; PROTEASOME; WNT PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; DOWN REGULATION; FAMILIAL DISEASE; GENE EXPRESSION; GENE MUTATION; HUMAN; MOLECULAR WEIGHT; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ACETYLCYSTEINE; ANIMALS; BETA CATENIN; CULTURE MEDIA, CONDITIONED; CYCLOHEXIMIDE; CYTOSKELETAL PROTEINS; DOWN-REGULATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; MEMBRANE PROTEINS; MICE; MUTATION; PHOSPHORYLATION; PRESENILIN-1; PROTEIN SYNTHESIS INHIBITORS; PROTEINS; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TIME FACTORS; TRANS-ACTIVATORS; TRANSFECTION; TUMOR CELLS, CULTURED; WNT PROTEINS; ZEBRAFISH PROTEINS;

ANIMALIA; STAPHYLOCOCCUS PHAGE 3A;

EID: 0034832025     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2001.02197.x     Document Type: Article

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