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Volumn 142, Issue 3, 2014, Pages 281-305

Metabotropic glutamatergic receptors and their ligands in drug addiction

Author keywords

Drug addiction; Glutamate; Metabotropic glutamatergic receptors; Relapse; Reward; Withdrawal

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 AMINO 3 PHOSPHONOPROPIONIC ACID; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 3,5 DIHYDROXYPHENYLGLYCINE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; 4 CARBOXY 2 METHYLPHENYLGLYCINE; 4 CARBOXYPHENYLGLYCINE; 6 METHYL 2 PHENYLAZO 3 PYRIDINOL; COCAINE; FENOBAM; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 5; GLUTAMIC ACID; LIGAND; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 4; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR 6; METABOTROPIC RECEPTOR 7; METABOTROPIC RECEPTOR 8; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; METHAMPHETAMINE; NICOTINE; OPIATE; UNINDEXED DRUG;

EID: 84898843029     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2013.12.012     Document Type: Review
Times cited : (75)

References (402)
  • 1
    • 0030981404 scopus 로고    scopus 로고
    • Anti-epileptogenic and anticonvulsant activity of L-2-amino-4- phosphonobutyrate, a presynaptic glutamate receptor agonist
    • DOI 10.1016/S0006-8993(97)00098-X, PII S000689939700098X
    • A.S. Abdul-Ghani, P.J. Attwell, N. Singh Kent, H.F. Bradford, M.J. Croucher, and D.E. Jane Anti-epileptogenic and anticonvulsant activity of l-2-amino-4-phosphonobutyrate, a presynaptic glutamate receptor agonist Brain Res 755 2 1997 202 212 (Pubitemid 27196326)
    • (1997) Brain Research , vol.755 , Issue.2 , pp. 202-212
    • Abdul-Ghani, A.-S.1    Attwell, P.J.E.2    Kent, N.S.3    Bradford, H.F.4    Croucher, M.J.5    Jane, D.E.6
  • 2
    • 84866324436 scopus 로고    scopus 로고
    • Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys
    • C. Achat-Mendes, D.M. Platt, and R.D. Spealman Antagonism of metabotropic glutamate 1 receptors attenuates behavioral effects of cocaine and methamphetamine in squirrel monkeys J Pharmacol Exp Ther 343 1 2012 214 224
    • (2012) J Pharmacol Exp Ther , vol.343 , Issue.1 , pp. 214-224
    • Achat-Mendes, C.1    Platt, D.M.2    Spealman, R.D.3
  • 3
    • 84878009124 scopus 로고    scopus 로고
    • A long-term, phase 2, multicenter, randomized, open-label, comparative safety study of pomaglumetad methionil (LY2140023 monohydrate) versus atypical antipsychotic standard of care in patients with schizophrenia
    • D.H. Adams, B.J. Kinon, S. Baygani, B.A. Millen, I. Velona, and S. Kollack-Walker et al. A long-term, phase 2, multicenter, randomized, open-label, comparative safety study of pomaglumetad methionil (LY2140023 monohydrate) versus atypical antipsychotic standard of care in patients with schizophrenia BMC Psychiatry 13 1 2013 143
    • (2013) BMC Psychiatry , vol.13 , Issue.1 , pp. 143
    • Adams, D.H.1    Kinon, B.J.2    Baygani, S.3    Millen, B.A.4    Velona, I.5    Kollack-Walker, S.6
  • 4
    • 33745966819 scopus 로고    scopus 로고
    • Pharmacological stimulation of group II metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys
    • DOI 10.1124/jpet.106.105387
    • A.S. Adewale, D.M. Platt, and R.D. Spealman Pharmacological stimulation of group ii metabotropic glutamate receptors reduces cocaine self-administration and cocaine-induced reinstatement of drug seeking in squirrel monkeys J Pharmacol Exp Ther 318 2 2006 922 931 (Pubitemid 44061269)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.318 , Issue.2 , pp. 922-931
    • Adewale, A.S.1    Platt, D.M.2    Spealman, R.D.3
  • 5
    • 0031006582 scopus 로고    scopus 로고
    • Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells
    • DOI 10.1016/S0028-3908(97)00051-8, PII S0028390897000518
    • G.K. Aghajanian, and G.J. Marek Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells Neuropharmacology 36 4-5 1997 589 599 (Pubitemid 27272104)
    • (1997) Neuropharmacology , vol.36 , Issue.4-5 , pp. 589-599
    • Aghajanian, G.K.1    Marek, G.J.2
  • 7
    • 0028139045 scopus 로고
    • Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice
    • DOI 10.1016/0092-8674(94)90204-6
    • A. Aiba, C. Chen, K. Herrup, C. Rosenmund, C.F. Stevens, and S. Tonegawa Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice Cell 79 2 1994 365 375 (Pubitemid 24324925)
    • (1994) Cell , vol.79 , Issue.2 , pp. 365-375
    • Aiba, A.1    Chen, C.2    Herrup, K.3    Rosenmund, C.4    Stevens, C.F.5    Tonegawa, S.6
  • 9
    • 34548348985 scopus 로고    scopus 로고
    • Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region, and prevents long-term spatial memory
    • DOI 10.1111/j.1460-9568.2007.05742.x
    • B. Altinbilek, and D. Manahan-Vaughan Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region, and prevents long-term spatial memory Eur J Neurosci 26 5 2007 1166 1172 (Pubitemid 47346760)
    • (2007) European Journal of Neuroscience , vol.26 , Issue.5 , pp. 1166-1172
    • Altinbilek, B.1    Manahan-Vaughan, D.2
  • 10
    • 84876731792 scopus 로고    scopus 로고
    • Palladium mediated (1)(1)C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [(1)(1)C]AZD9272
    • J.D. Andersson, N. Seneca, P. Truong, D. Wensbo, P. Raboisson, and L. Farde et al. Palladium mediated (1)(1)C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [(1)(1)C]AZD9272 Nucl Med Biol 40 4 2013 547 553
    • (2013) Nucl Med Biol , vol.40 , Issue.4 , pp. 547-553
    • Andersson, J.D.1    Seneca, N.2    Truong, P.3    Wensbo, D.4    Raboisson, P.5    Farde, L.6
  • 11
    • 0035927783 scopus 로고    scopus 로고
    • Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer
    • DOI 10.1038/35082096
    • F. Ango, L. Prezeau, T. Muller, J.C. Tu, B. Xiao, and P.F. Worley et al. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein homer Nature 411 6840 2001 962 965 (Pubitemid 32601494)
    • (2001) Nature , vol.411 , Issue.6840 , pp. 962-965
    • Ango, F.1    Prezeau, L.2    Muller, T.3    Tu, J.C.4    Xiao, B.5    Worley, P.F.6    Pin, J.P.7    Bockaert, J.8    Fagni, L.9
  • 12
    • 0032907608 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Electrophysiological properties and role in plasticity
    • DOI 10.1016/S0165-0173(98)00050-2, PII S0165017398000502
    • R. Anwyl Metabotropic glutamate receptors: electrophysiological properties and role in plasticity Brain Res Brain Res Rev 29 1 1999 83 120 (Pubitemid 29016081)
    • (1999) Brain Research Reviews , vol.29 , Issue.1 , pp. 83-120
    • Anwyl, R.1
  • 13
    • 0034332480 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
    • H. Awad, G.W. Hubert, Y. Smith, A.I. Levey, and P.J. Conn Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus J Neurosci 20 21 2000 7871 7879
    • (2000) J Neurosci , vol.20 , Issue.21 , pp. 7871-7879
    • Awad, H.1    Hubert, G.W.2    Smith, Y.3    Levey, A.I.4    Conn, P.J.5
  • 14
    • 67651087294 scopus 로고    scopus 로고
    • MGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning
    • J.E. Ayala, Y. Chen, J.L. Banko, D.J. Sheffler, R. Williams, and A.N. Telk et al. mGluR5 positive allosteric modulators facilitate both hippocampal LTP and LTD and enhance spatial learning Neuropsychopharmacology 34 9 2009 2057 2071
    • (2009) Neuropsychopharmacology , vol.34 , Issue.9 , pp. 2057-2071
    • Ayala, J.E.1    Chen, Y.2    Banko, J.L.3    Sheffler, D.J.4    Williams, R.5    Telk, A.N.6
  • 15
    • 9644272348 scopus 로고    scopus 로고
    • MGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior
    • DOI 10.1038/sj.npp.1300381
    • P. Backstrom, D. Bachteler, S. Koch, P. Hyytia, and R. Spanagel mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior Neuropsychopharmacology 29 5 2004 921 928 (Pubitemid 38526792)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.5 , pp. 921-928
    • Backstrom, P.1    Bachteler, D.2    Koch, S.3    Hyytia, P.4    Spanagel, R.5
  • 16
    • 28844433298 scopus 로고    scopus 로고
    • Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG
    • DOI 10.1016/j.ejphar.2005.10.051, PII S0014299905011192
    • P. Backstrom, and P. Hyytia Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG Eur J Pharmacol 528 1-3 2005 110 118 (Pubitemid 41773660)
    • (2005) European Journal of Pharmacology , vol.528 , Issue.1-3 , pp. 110-118
    • Backstrom, P.1    Hyytia, P.2
  • 17
    • 33645025726 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking
    • P. Backstrom, and P. Hyytia Ionotropic and metabotropic glutamate receptor antagonism attenuates cue-induced cocaine seeking Neuropsychopharmacology 31 4 2006 778 786
    • (2006) Neuropsychopharmacology , vol.31 , Issue.4 , pp. 778-786
    • Backstrom, P.1    Hyytia, P.2
  • 18
    • 84857645587 scopus 로고    scopus 로고
    • Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats
    • A. Bahi, K. Fizia, M. Dietz, F. Gasparini, and P.J. Flor Pharmacological modulation of mGluR7 with AMN082 and MMPIP exerts specific influences on alcohol consumption and preference in rats Addict Biol 17 2 2012 235 247
    • (2012) Addict Biol , vol.17 , Issue.2 , pp. 235-247
    • Bahi, A.1    Fizia, K.2    Dietz, M.3    Gasparini, F.4    Flor, P.J.5
  • 20
    • 2442672865 scopus 로고    scopus 로고
    • Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: Comparison between cocaine and a potent conventional reinforcer
    • DOI 10.1523/JNEUROSCI.0176-04.2004
    • M.A. Baptista, R. Martin-Fardon, and F. Weiss Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer J Neurosci 24 20 2004 4723 4727 (Pubitemid 38668196)
    • (2004) Journal of Neuroscience , vol.24 , Issue.20 , pp. 4723-4727
    • Baptista, M.A.S.1    Martin-Fardon, R.2    Weiss, F.3
  • 21
    • 0141755379 scopus 로고    scopus 로고
    • Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models
    • DOI 10.1016/j.eplepsyres.2003.08.001
    • M.E. Barton, S.C. Peters, and H.E. Shannon Comparison of the effect of glutamate receptor modulators in the 6 Hz and maximal electroshock seizure models Epilepsy Res 56 1 2003 17 26 (Pubitemid 37177052)
    • (2003) Epilepsy Research , vol.56 , Issue.1 , pp. 17-26
    • Barton, M.E.1    Peters, S.C.2    Shannon, H.E.3
  • 22
    • 0026344031 scopus 로고
    • Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus
    • A. Baskys, and R.C. Malenka Agonists at metabotropic glutamate receptors presynaptically inhibit EPSCs in neonatal rat hippocampus J Physiol 444 1991 687 701
    • (1991) J Physiol , vol.444 , pp. 687-701
    • Baskys, A.1    Malenka, R.C.2
  • 23
    • 0034948146 scopus 로고    scopus 로고
    • Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission
    • DOI 10.1006/mcne.2001.0992
    • G. Battaglia, V. Bruno, A. Pisani, D. Centonze, M.V. Catania, and P. Calabresi et al. Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission Mol Cell Neurosci 17 6 2001 1071 1083 (Pubitemid 32641875)
    • (2001) Molecular and Cellular Neuroscience , vol.17 , Issue.6 , pp. 1071-1083
    • Battaglia, G.1    Bruno, V.2    Pisani, A.3    Centonze, D.4    Catania, M.V.5    Calabresi, P.6    Nicoletti, F.7
  • 24
    • 33746233386 scopus 로고    scopus 로고
    • Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine
    • G. Battaglia, C.L. Busceti, G. Molinaro, F. Biagioni, A. Traficante, and F. Nicoletti et al. Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine J Neurosci 26 27 2006 7222 7229
    • (2006) J Neurosci , vol.26 , Issue.27 , pp. 7222-7229
    • Battaglia, G.1    Busceti, C.L.2    Molinaro, G.3    Biagioni, F.4    Traficante, A.5    Nicoletti, F.6
  • 26
    • 70349216322 scopus 로고    scopus 로고
    • Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys
    • R.M. Bauzo, H.L. Kimmel, and L.L. Howell Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys Pharmacol Biochem Behav 94 1 2009 204 210
    • (2009) Pharmacol Biochem Behav , vol.94 , Issue.1 , pp. 204-210
    • Bauzo, R.M.1    Kimmel, H.L.2    Howell, L.L.3
  • 27
    • 0029561572 scopus 로고
    • Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs)
    • J.S. Bedingfield, M.C. Kemp, D.E. Jane, H. Tse, P.J. Roberts, and J.C. Watkins Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs) Br J Pharmacol 116 8 1995 3323 3329 (Pubitemid 26007779)
    • (1995) British Journal of Pharmacology , vol.116 , Issue.8 , pp. 3323-3329
    • Bedingfield, J.S.1    Kemp, M.C.2    Jane, D.E.3    Tse, H.-W.4    Roberts, P.J.5    Watkins, J.C.6
  • 28
    • 33751190762 scopus 로고    scopus 로고
    • Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
    • DOI 10.1016/j.euroneuro.2006.03.002, PII S0924977X06000496
    • I.V. Belozertseva, T. Kos, P. Popik, W. Danysz, and A.Y. Bespalov Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests Eur Neuropsychopharmacol 17 3 2007 172 179 (Pubitemid 44779190)
    • (2007) European Neuropsychopharmacology , vol.17 , Issue.3 , pp. 172-179
    • Belozertseva, I.V.1    Kos, T.2    Popik, P.3    Danysz, W.4    Bespalov, A.Y.5
  • 29
    • 34547198448 scopus 로고    scopus 로고
    • A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis
    • DOI 10.1124/mol.107.035170
    • M.A. Benneyworth, Z. Xiang, R.L. Smith, E.E. Garcia, P.J. Conn, and E. Sanders-Bush A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis Mol Pharmacol 72 2 2007 477 484 (Pubitemid 47124127)
    • (2007) Molecular Pharmacology , vol.72 , Issue.2 , pp. 477-484
    • Benneyworth, M.A.1    Xiang, Z.2    Smith, R.L.3    Garcia, E.E.4    Conn, P.J.5    Sanders-Bush, E.6
  • 30
    • 0037112011 scopus 로고    scopus 로고
    • Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes
    • P. Benquet, C.E. Gee, and U. Gerber Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes J Neurosci 22 22 2002 9679 9686 (Pubitemid 35332851)
    • (2002) Journal of Neuroscience , vol.22 , Issue.22 , pp. 9679-9686
    • Benquet, P.1    Gee, C.E.2    Gerber, U.3
  • 31
    • 84872080458 scopus 로고    scopus 로고
    • Deficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administration
    • O. Ben-Shahar, A.D. Sacramento, B.W. Miller, S.M. Webb, M.G. Wroten, and H.E. Silva et al. Deficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administration J Neurosci 33 2 2013 495 506a
    • (2013) J Neurosci , vol.33 , Issue.2
    • Ben-Shahar, O.1    Sacramento, A.D.2    Miller, B.W.3    Webb, S.M.4    Wroten, M.G.5    Silva, H.E.6
  • 32
    • 70350455902 scopus 로고    scopus 로고
    • Altered G-protein coupling in an mGluR6 point mutant associated with congenital stationary night blindness
    • D. Beqollari, M.J. Betzenhauser, and P.J. Kammermeier Altered G-protein coupling in an mGluR6 point mutant associated with congenital stationary night blindness Mol Pharmacol 76 5 2009 992 997
    • (2009) Mol Pharmacol , vol.76 , Issue.5 , pp. 992-997
    • Beqollari, D.1    Betzenhauser, M.J.2    Kammermeier, P.J.3
  • 33
    • 38749110355 scopus 로고    scopus 로고
    • Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats
    • J. Besheer, S. Faccidomo, J.J. Grondin, and C.W. Hodge Effects of mGlu1-receptor blockade on ethanol self-administration in inbred alcohol-preferring rats Alcohol 42 1 2008 13 20
    • (2008) Alcohol , vol.42 , Issue.1 , pp. 13-20
    • Besheer, J.1    Faccidomo, S.2    Grondin, J.J.3    Hodge, C.W.4
  • 34
    • 38349105319 scopus 로고    scopus 로고
    • Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats
    • J. Besheer, S. Faccidomo, J.J. Grondin, and C.W. Hodge Regulation of motivation to self-administer ethanol by mGluR5 in alcohol-preferring (P) rats Alcohol Clin Exp Res 32 2 2008 209 221
    • (2008) Alcohol Clin Exp Res , vol.32 , Issue.2 , pp. 209-221
    • Besheer, J.1    Faccidomo, S.2    Grondin, J.J.3    Hodge, C.W.4
  • 35
    • 77950356499 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake
    • J. Besheer, J.J. Grondin, R. Cannady, A.C. Sharko, S. Faccidomo, and C.W. Hodge Metabotropic glutamate receptor 5 activity in the nucleus accumbens is required for the maintenance of ethanol self-administration in a rat genetic model of high alcohol intake Biol Psychiatry 67 9 2010 812 822
    • (2010) Biol Psychiatry , vol.67 , Issue.9 , pp. 812-822
    • Besheer, J.1    Grondin, J.J.2    Cannady, R.3    Sharko, A.C.4    Faccidomo, S.5    Hodge, C.W.6
  • 36
    • 68049148068 scopus 로고    scopus 로고
    • Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens
    • J. Besheer, J.J. Grondin, M.C. Salling, M. Spanos, R.A. Stevenson, and C.W. Hodge Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens J Neurosci 29 30 2009 9582 9591
    • (2009) J Neurosci , vol.29 , Issue.30 , pp. 9582-9591
    • Besheer, J.1    Grondin, J.J.2    Salling, M.C.3    Spanos, M.4    Stevenson, R.A.5    Hodge, C.W.6
  • 37
    • 33750448347 scopus 로고    scopus 로고
    • 5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats
    • DOI 10.1016/j.ejphar.2006.08.071, PII S0014299906009563
    • J. Besheer, R.A. Stevenson, and C.W. Hodge mGlu5 receptors are involved in the discriminative stimulus effects of self-administered ethanol in rats Eur J Pharmacol 551 1-3 2006 71 75 (Pubitemid 44648053)
    • (2006) European Journal of Pharmacology , vol.551 , Issue.1-3 , pp. 71-75
    • Besheer, J.1    Stevenson, R.A.2    Hodge, C.W.3
  • 38
    • 23644451337 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
    • DOI 10.1016/j.neuropharm.2005.06.007, PII S0028390805002212
    • A.Y. Bespalov, O.A. Dravolina, I. Sukhanov, E. Zakharova, E. Blokhina, and E. Zvartau et al. Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats Neuropharmacology 49 Suppl. 1 2005 167 178 (Pubitemid 41115903)
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. , pp. 167-178
    • Bespalov, A.Y.1    Dravolina, O.A.2    Sukhanov, I.3    Zakharova, E.4    Blokhina, E.5    Zvartau, E.6    Danysz, W.7    Van Heeke, G.8    Markou, A.9
  • 39
    • 84864472836 scopus 로고    scopus 로고
    • Allosteric modulation of the group III mGlu(4) receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson's disease
    • M.J. Betts, M.J. O'Neill, and S. Duty Allosteric modulation of the group III mGlu(4) receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson's disease Br J Pharmacol 166 8 2012 2317 2330
    • (2012) Br J Pharmacol , vol.166 , Issue.8 , pp. 2317-2330
    • Betts, M.J.1    O'Neill, M.J.2    Duty, S.3
  • 40
    • 70349695699 scopus 로고    scopus 로고
    • Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism
    • C. Beurrier, S. Lopez, D. Revy, C. Selvam, C. Goudet, and M. Lherondel et al. Electrophysiological and behavioral evidence that modulation of metabotropic glutamate receptor 4 with a new agonist reverses experimental parkinsonism FASEB J 23 10 2009 3619 3628
    • (2009) FASEB J , vol.23 , Issue.10 , pp. 3619-3628
    • Beurrier, C.1    Lopez, S.2    Revy, D.3    Selvam, C.4    Goudet, C.5    Lherondel, M.6
  • 41
    • 50849097895 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice
    • M.K. Bird, J. Kirchhoff, E. Djouma, and A.J. Lawrence Metabotropic glutamate 5 receptors regulate sensitivity to ethanol in mice Int J Neuropsychopharmacol 11 6 2008 765 774
    • (2008) Int J Neuropsychopharmacol , vol.11 , Issue.6 , pp. 765-774
    • Bird, M.K.1    Kirchhoff, J.2    Djouma, E.3    Lawrence, A.J.4
  • 42
    • 77949656831 scopus 로고    scopus 로고
    • Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice
    • M.K. Bird, C.A. Reid, F. Chen, H.O. Tan, S. Petrou, and A.J. Lawrence Cocaine-mediated synaptic potentiation is absent in VTA neurons from mGlu5-deficient mice Int J Neuropsychopharmacol 13 2 2010 133 141
    • (2010) Int J Neuropsychopharmacol , vol.13 , Issue.2 , pp. 133-141
    • Bird, M.K.1    Reid, C.A.2    Chen, F.3    Tan, H.O.4    Petrou, S.5    Lawrence, A.J.6
  • 43
    • 14344256202 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol
    • DOI 10.1016/j.alcohol.2004.10.003
    • Y.A. Blednov, D. Walker, E. Osterndorf-Kahanek, and R.A. Harris Mice lacking metabotropic glutamate receptor 4 do not show the motor stimulatory effect of ethanol Alcohol 34 2-3 2004 251 259 (Pubitemid 40292784)
    • (2004) Alcohol , vol.34 , Issue.2-3 , pp. 251-259
    • Blednov, Y.A.1    Walker, D.2    Osterndorf-Kahanek, E.3    Harris, R.A.4
  • 44
    • 4644260473 scopus 로고    scopus 로고
    • GPCR interacting proteins (GIP)
    • DOI 10.1016/j.pharmthera.2004.06.004, PII S0163725804001007
    • J. Bockaert, L. Fagni, A. Dumuis, and P. Marin GPCR interacting proteins (GIP) Pharmacol Ther 103 3 2004 203 221 (Pubitemid 39298464)
    • (2004) Pharmacology and Therapeutics , vol.103 , Issue.3 , pp. 203-221
    • Bockaert, J.1    Fagni, L.2    Dumuis, A.3    Marin, P.4
  • 45
    • 21344434071 scopus 로고    scopus 로고
    • 2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking
    • DOI 10.1097/00001756-200506210-00026
    • J.M. Bossert, R.F. Busch, and S.M. Gray The novel mGluR2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking Neuroreport 16 9 2005 1013 1016 (Pubitemid 40904757)
    • (2005) NeuroReport , vol.16 , Issue.9 , pp. 1013-1016
    • Bossert, J.M.1    Busch, R.F.2    Gray, S.M.3
  • 46
    • 33748760601 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking
    • DOI 10.1038/sj.npp.1300977, PII 1300977
    • J.M. Bossert, S.M. Gray, L. Lu, and Y. Shaham Activation of group II metabotropic glutamate receptors in the nucleus accumbens shell attenuates context-induced relapse to heroin seeking Neuropsychopharmacology 31 10 2006 2197 2209 (Pubitemid 44413197)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2197-2209
    • Bossert, J.M.1    Gray, S.M.2    Lu, L.3    Shaham, Y.4
  • 47
    • 0031713304 scopus 로고    scopus 로고
    • Comparative effect of l-CCG-I, DCG-IV and γ-carboxy-l-glutamate on all cloned metabotropic glutamate receptor subtypes
    • DOI 10.1016/S0028-3908(98)00091-4, PII S0028390898000914
    • I. Brabet, M.L. Parmentier, C. De Colle, J. Bockaert, F. Acher, and J.P. Pin Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-l-glutamate on all cloned metabotropic glutamate receptor subtypes Neuropharmacology 37 8 1998 1043 1051 (Pubitemid 28401493)
    • (1998) Neuropharmacology , vol.37 , Issue.8 , pp. 1043-1051
    • Brabet, I.1    Parmentier, M.-L.2    De Colle, C.3    Bockaert, J.4    Acher, F.5    Pin, J.-P.6
  • 48
    • 0029863890 scopus 로고    scopus 로고
    • Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies
    • S.R. Bradley, A.I. Levey, S.M. Hersch, and P.J. Conn Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies J Neurosci 16 6 1996 2044 2056 (Pubitemid 26144017)
    • (1996) Journal of Neuroscience , vol.16 , Issue.6 , pp. 2044-2056
    • Bradley, S.R.1    Levey, A.I.2    Hersch, S.M.3    Conn, P.J.4
  • 49
    • 0031753033 scopus 로고    scopus 로고
    • Distribution and developmental regulation of metabotropic glutamate receptor 7a in rat brain
    • S.R. Bradley, H.D. Rees, H. Yi, A.I. Levey, and P.J. Conn Distribution and developmental regulation of metabotropic glutamate receptor 7a in rat brain J Neurochem 71 2 1998 636 645 (Pubitemid 28480411)
    • (1998) Journal of Neurochemistry , vol.71 , Issue.2 , pp. 636-645
    • Bradley, S.R.1    Rees, H.D.2    Yi, H.3    Levey, A.I.4    Conn, P.J.5
  • 50
    • 0033611972 scopus 로고    scopus 로고
    • Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia
    • DOI 10.1002/(SICI)1096-9861(19990428)407: 1<33::AID-CNE3>3.0.CO;2-G
    • S.R. Bradley, D.G. Standaert, K.J. Rhodes, H.D. Rees, C.M. Testa, and A.I. Levey et al. Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia J Comp Neurol 407 1 1999 33 46 (Pubitemid 29161991)
    • (1999) Journal of Comparative Neurology , vol.407 , Issue.1 , pp. 33-46
    • Bradley, S.R.1    Standaert, D.G.2    Rhodes, K.J.3    Rees, H.D.4    Testa, C.M.5    Levey, A.I.6    Conn, P.J.7
  • 51
    • 83455229501 scopus 로고    scopus 로고
    • The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling
    • S.R. Bradley, J.M. Uslaner, R.B. Flick, A. Lee, K.M. Groover, and P.H. Hutson The mGluR7 allosteric agonist AMN082 produces antidepressant-like effects by modulating glutamatergic signaling Pharmacol Biochem Behav 101 1 2012 35 40
    • (2012) Pharmacol Biochem Behav , vol.101 , Issue.1 , pp. 35-40
    • Bradley, S.R.1    Uslaner, J.M.2    Flick, R.B.3    Lee, A.4    Groover, K.M.5    Hutson, P.H.6
  • 52
    • 28144437734 scopus 로고    scopus 로고
    • Neuroscience: Nucleus accumbens long-term depression and the expression of behavioral sensitization
    • DOI 10.1126/science.1116894
    • K. Brebner, T.P. Wong, L. Liu, Y. Liu, P. Campsall, and S. Gray et al. Nucleus accumbens long-term depression and the expression of behavioral sensitization Science 310 5752 2005 1340 1343 (Pubitemid 41698868)
    • (2005) Science , vol.310 , Issue.5752 , pp. 1340-1343
    • Brebner, K.1    Wong, T.P.2    Liu, L.3    Liu, Y.4    Campsall, P.5    Gray, S.6    Phelps, L.7    Phillips, A.G.8    Wang, Y.T.9
  • 53
    • 84882784373 scopus 로고    scopus 로고
    • Biotransformation of a novel positive allosteric modulator of mGlu5 contributes to seizures in rats involving a receptor agonism-dependent mechanism
    • T.M. Bridges, J.M. Rook, M.J. Noetzel, R.D. Morrison, Y. Zhou, and R.D. Gogliotti et al. Biotransformation of a novel positive allosteric modulator of mGlu5 contributes to seizures in rats involving a receptor agonism-dependent mechanism Drug Metab Dispos 41 9 2013 1703 1714
    • (2013) Drug Metab Dispos , vol.41 , Issue.9 , pp. 1703-1714
    • Bridges, T.M.1    Rook, J.M.2    Noetzel, M.J.3    Morrison, R.D.4    Zhou, Y.5    Gogliotti, R.D.6
  • 54
    • 84856316283 scopus 로고    scopus 로고
    • Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata
    • M. Broadstock, P.J. Austin, M.J. Betts, and S. Duty Antiparkinsonian potential of targeting group III metabotropic glutamate receptor subtypes in the rodent substantia nigra pars reticulata Br J Pharmacol 165 4b 2012 1034 1045
    • (2012) Br J Pharmacol , vol.165 B , Issue.4 , pp. 1034-1045
    • Broadstock, M.1    Austin, P.J.2    Betts, M.J.3    Duty, S.4
  • 55
    • 0035996363 scopus 로고    scopus 로고
    • Anxiolytic-like activity of the mGluR5 antagonist MPEP: A comparison with diazepam and buspirone
    • DOI 10.1016/S0091-3057(02)00828-6, PII S0091305702008286
    • J. Brodkin, C. Busse, S.J. Sukoff, and M.A. Varney Anxiolytic-like activity of the mGluR5 antagonist MPEP: a comparison with diazepam and buspirone Pharmacol Biochem Behav 73 2 2002 359 366 (Pubitemid 34773437)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.2 , pp. 359-366
    • Brodkin, J.1    Busse, C.2    Sukoff, S.J.3    Varney, M.A.4
  • 56
    • 0347419233 scopus 로고    scopus 로고
    • Disruption of prepulse inhibition in mice lacking mGluR1
    • DOI 10.1111/j.1460-9568.2003.03073.x
    • S.A. Brody, F. Conquet, and M.A. Geyer Disruption of prepulse inhibition in mice lacking mGluR1 Eur J Neurosci 18 12 2003 3361 3366 (Pubitemid 38031061)
    • (2003) European Journal of Neuroscience , vol.18 , Issue.12 , pp. 3361-3366
    • Brody, S.A.1    Conquet, F.2    Geyer, M.A.3
  • 57
    • 84861224182 scopus 로고    scopus 로고
    • The mGlu5 receptor antagonist MTEP attenuates opiate self-administration and cue-induced opiate-seeking behaviour in mice
    • R.M. Brown, M.R. Stagnitti, J.R. Duncan, and A.J. Lawrence The mGlu5 receptor antagonist MTEP attenuates opiate self-administration and cue-induced opiate-seeking behaviour in mice Drug Alcohol Depend 123 1-3 2012 264 268
    • (2012) Drug Alcohol Depend , vol.123 , Issue.13 , pp. 264-268
    • Brown, R.M.1    Stagnitti, M.R.2    Duncan, J.R.3    Lawrence, A.J.4
  • 59
    • 67650089750 scopus 로고    scopus 로고
    • Molecular dynamics simulation of the heterodimeric mGluR2/5HT(2A) complex. An atomistic resolution study of a potential new target in psychiatric conditions
    • A. Bruno, A.E. Guadix, and G. Costantino Molecular dynamics simulation of the heterodimeric mGluR2/5HT(2A) complex. An atomistic resolution study of a potential new target in psychiatric conditions J Chem Inf Model 49 6 2009 1602 1616
    • (2009) J Chem Inf Model , vol.49 , Issue.6 , pp. 1602-1616
    • Bruno, A.1    Guadix, A.E.2    Costantino, G.3
  • 61
    • 0028932444 scopus 로고
    • Antagonism of the synaptic depressant actions of l-AP4 in the lateral pepforant path by MAP4
    • T.J. Bushell, D.E. Jane, H. Tse, J.C. Watkins, C.H. Davies, and J. Garthwaite et al. Antagonism of the synaptic depressant actions of l-AP4 in the lateral pepforant path by MAP4 Neuropharmacology 34 2 1995 239 241
    • (1995) Neuropharmacology , vol.34 , Issue.2 , pp. 239-241
    • Bushell, T.J.1    Jane, D.E.2    Tse, H.3    Watkins, J.C.4    Davies, C.H.5    Garthwaite, J.6
  • 62
    • 3042685523 scopus 로고    scopus 로고
    • The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine (MTEP) in rodent models of anxiety
    • DOI 10.1038/sj.npp.1300540
    • C.S. Busse, J. Brodkin, D. Tattersall, J.J. Anderson, N. Warren, and L. Tehrani et al. The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety Neuropsychopharmacology 29 11 2004 1971 1979 (Pubitemid 39486548)
    • (2004) Neuropsychopharmacology , vol.29 , Issue.11 , pp. 1971-1979
    • Busse, C.S.1    Brodkin, J.2    Tattersall, D.3    Andersen, J.J.4    Warren, N.5    Tehrani, L.6    Bristow, L.J.7    Varney, M.A.8    Cosford, N.D.P.9
  • 63
    • 70149094992 scopus 로고    scopus 로고
    • Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type i mechanoreceptor units in the rat sinus hair follicle
    • P.M. Cahusac, and S.C. Mavulati Non-competitive metabotropic glutamate 1 receptor antagonists block activity of slowly adapting type I mechanoreceptor units in the rat sinus hair follicle Neuroscience 163 3 2009 933 941
    • (2009) Neuroscience , vol.163 , Issue.3 , pp. 933-941
    • Cahusac, P.M.1    Mavulati, S.C.2
  • 65
    • 80052766574 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala
    • R. Cannady, J.J. Grondin, K.R. Fisher, C.W. Hodge, and J. Besheer Activation of group II metabotropic glutamate receptors inhibits the discriminative stimulus effects of alcohol via selective activity within the amygdala Neuropsychopharmacology 36 11 2011 2328 2338
    • (2011) Neuropsychopharmacology , vol.36 , Issue.11 , pp. 2328-2338
    • Cannady, R.1    Grondin, J.J.2    Fisher, K.R.3    Hodge, C.W.4    Besheer, J.5
  • 66
    • 0033844601 scopus 로고    scopus 로고
    • Regulation of neurotransmitter release by metabotropic glutamate receptors
    • DOI 10.1046/j.1471-4159.2000.0750889.x
    • J. Cartmell, and D.D. Schoepp Regulation of neurotransmitter release by metabotropic glutamate receptors J Neurochem 75 3 2000 889 907 (Pubitemid 30660476)
    • (2000) Journal of Neurochemistry , vol.75 , Issue.3 , pp. 889-907
    • Cartmell, J.1    Schoepp, D.D.2
  • 68
    • 0035919557 scopus 로고    scopus 로고
    • 4α receptor selective agonist, (1S,3R,4S)-1-aminocyclopentane-1,2,4-tricarboxylic acid
    • DOI 10.1016/S0014-2999(01)01013-5, PII S0014299901010135
    • A.G. Chapman, A. Talebi, P.K. Yip, and B.S. Meldrum Anticonvulsant activity of a mGlu(4alpha) receptor selective agonist, (1S,3R,4S)-1- aminocyclopentane-1,2,4-tricarboxylic acid Eur J Pharmacol 424 2 2001 107 113 (Pubitemid 32718614)
    • (2001) European Journal of Pharmacology , vol.424 , Issue.2 , pp. 107-113
    • Chapman, A.G.1    Talebi, A.2    Yip, P.K.3    Meldrum, B.S.4
  • 69
    • 0032761575 scopus 로고    scopus 로고
    • Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl) propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model
    • Y. Chen, G. Bacon, E. Sher, B.P. Clark, M.J. Kallman, and R.A. Wright et al. Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl) propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model Neuroscience 95 3 2000 787 793
    • (2000) Neuroscience , vol.95 , Issue.3 , pp. 787-793
    • Chen, Y.1    Bacon, G.2    Sher, E.3    Clark, B.P.4    Kallman, M.J.5    Wright, R.A.6
  • 70
    • 34247477329 scopus 로고    scopus 로고
    • Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses
    • DOI 10.1124/mol.106.032425
    • Y. Chen, Y. Nong, C. Goudet, K. Hemstapat, T. de Paulis, and J.P. Pin et al. Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses Mol Pharmacol 71 5 2007 1389 1398 (Pubitemid 46661543)
    • (2007) Molecular Pharmacology , vol.71 , Issue.5 , pp. 1389-1398
    • Chen, Y.1    Nong, Y.2    Goudet, C.3    Hemstapat, K.4    De Paulis, T.5    Pin, J.-P.6    Conn, P.J.7
  • 71
    • 84881610365 scopus 로고    scopus 로고
    • SNARE proteins are essential in the potentiation of NMDA receptors by group II metabotropic glutamate receptors
    • J. Cheng, W. Liu, L.J. Duffney, and Z. Yan SNARE proteins are essential in the potentiation of NMDA receptors by group II metabotropic glutamate receptors J Physiol 591 16 2013 3935 3947
    • (2013) J Physiol , vol.591 , Issue.16 , pp. 3935-3947
    • Cheng, J.1    Liu, W.2    Duffney, L.J.3    Yan, Z.4
  • 73
    • 84857238962 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and the control of chronic pain
    • S. Chiechio, and F. Nicoletti Metabotropic glutamate receptors and the control of chronic pain Curr Opin Pharmacol 12 1 2012 28 34
    • (2012) Curr Opin Pharmacol , vol.12 , Issue.1 , pp. 28-34
    • Chiechio, S.1    Nicoletti, F.2
  • 74
    • 79951835556 scopus 로고    scopus 로고
    • MGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration
    • R.M. Cleva, M.P. Hicks, J.T. Gass, K.C. Wischerath, E.T. Plasters, and J.J. Widholm et al. mGluR5 positive allosteric modulation enhances extinction learning following cocaine self-administration Behav Neurosci 125 1 2011 10 19
    • (2011) Behav Neurosci , vol.125 , Issue.1 , pp. 10-19
    • Cleva, R.M.1    Hicks, M.P.2    Gass, J.T.3    Wischerath, K.C.4    Plasters, E.T.5    Widholm, J.J.6
  • 76
    • 84865984526 scopus 로고    scopus 로고
    • Differential modulation of thresholds for intracranial self-stimulation by mGlu5 positive and negative allosteric modulators: Implications for effects on drug self-administration
    • R.M. Cleva, L.R. Watterson, M.A. Johnson, and M.F. Olive Differential modulation of thresholds for intracranial self-stimulation by mGlu5 positive and negative allosteric modulators: implications for effects on drug self-administration Front Pharmacol 2 2012 93
    • (2012) Front Pharmacol , vol.2 , pp. 93
    • Cleva, R.M.1    Watterson, L.R.2    Johnson, M.A.3    Olive, M.F.4
  • 77
    • 0034616099 scopus 로고    scopus 로고
    • Pharmacological characterization of the rat metabotropic glutamate receptor type 8a revealed strong similarities and slight differences with the type 4a receptor
    • DOI 10.1016/S0014-2999(00)00113-8, PII S0014299900001138
    • C.D. Colle, A. Bessis, J. Bockaert, F. Acher, and J. Pin Pharmacological characterization of the rat metabotropic glutamate receptor type 8a revealed strong similarities and slight differences with the type 4a receptor Eur J Pharmacol 394 1 2000 17 26 (Pubitemid 30193283)
    • (2000) European Journal of Pharmacology , vol.394 , Issue.1 , pp. 17-26
    • De Colle, C.1    Bessis, A.-S.2    Bockaert, J.3    Acher, F.4    Pin, J.-P.5
  • 80
    • 0037139302 scopus 로고    scopus 로고
    • Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS
    • DOI 10.1016/S0306-4522(01)00591-7, PII S0306452201005917
    • C. Corti, L. Aldegheri, P. Somogyi, and F. Ferraguti Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS Neuroscience 110 3 2002 403 420 (Pubitemid 34242771)
    • (2002) Neuroscience , vol.110 , Issue.3 , pp. 403-420
    • Corti, C.1    Aldegheri, L.2    Somogyi, P.3    Ferraguti, F.4
  • 81
    • 34547686245 scopus 로고    scopus 로고
    • The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/ neuroprotection
    • DOI 10.1523/JNEUROSCI.1889-07.2007
    • C. Corti, G. Battaglia, G. Molinaro, B. Riozzi, A. Pittaluga, and M. Corsi et al. The use of knock-out mice unravels distinct roles for mGlu2 and mGlu3 metabotropic glutamate receptors in mechanisms of neurodegeneration/ neuroprotection J Neurosci 27 31 2007 8297 8308 (Pubitemid 47219630)
    • (2007) Journal of Neuroscience , vol.27 , Issue.31 , pp. 8297-8308
    • Corti, C.1    Battaglia, G.2    Molinaro, G.3    Riozzi, B.4    Pittaluga, A.5    Corsi, M.6    Mugnaini, M.7    Nicoletti, F.8    Bruno, V.9
  • 82
    • 34547692661 scopus 로고    scopus 로고
    • Altered Dimerization of Metabotropic Glutamate Receptor 3 in Schizophrenia
    • DOI 10.1016/j.biopsych.2006.12.005, PII S0006322306015563, Molecular Mechanisms, Brain Development, and Novel Treatment Mechanisms for Schizophrenia
    • C. Corti, L. Crepaldi, S. Mion, A.L. Roth, J.H. Xuereb, and F. Ferraguti Altered dimerization of metabotropic glutamate receptor 3 in schizophrenia Biol Psychiatry 62 7 2007 747 755 (Pubitemid 47374649)
    • (2007) Biological Psychiatry , vol.62 , Issue.7 , pp. 747-755
    • Corti, C.1    Crepaldi, L.2    Mion, S.3    Roth, A.L.4    Xuereb, J.H.5    Ferraguti, F.6
  • 83
    • 0032449643 scopus 로고    scopus 로고
    • Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8
    • DOI 10.1046/j.1460-9568.1998.00371.x
    • C. Corti, S. Restituito, J.M. Rimland, I. Brabet, M. Corsi, and J.P. Pin et al. Cloning and characterization of alternative mRNA forms for the rat metabotropic glutamate receptors mGluR7 and mGluR8 Eur J Neurosci 10 12 1998 3629 3641 (Pubitemid 29073920)
    • (1998) European Journal of Neuroscience , vol.10 , Issue.12 , pp. 3629-3641
    • Corti, C.1    Restituito, S.2    Rimland, J.M.3    Brabet, I.4    Corsi, M.5    Pin, J.P.6    Ferraguti, F.7
  • 85
    • 0035080723 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 2-(3′-(1H-tetrazol-5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist
    • DOI 10.1016/S0968-0896(00)00270-4, PII S0968089600002704
    • G. Costantino, K. Maltoni, M. Marinozzi, E. Camaioni, L. Prezeau, and J.P. Pin et al. Synthesis and biological evaluation of 2-(3′-(1H-tetrazol- 5-yl) bicyclo[1.1.1]pent-1-yl)glycine (S-TBPG), a novel mGlu1 receptor antagonist Bioorg Med Chem 9 2 2001 221 227 (Pubitemid 32244021)
    • (2001) Bioorganic and Medicinal Chemistry , vol.9 , Issue.2 , pp. 221-227
    • Costantino, G.1    Maltoni, K.2    Marinozzi, M.3    Camaioni, E.4    Prezeau, L.5    Pin, J.-P.6    Pellicciari, R.7
  • 86
    • 84865965127 scopus 로고    scopus 로고
    • Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-The-dark procedures
    • D.K. Cozzoli, J. Courson, A.L. Caruana, B.W. Miller, D.I. Greentree, and A.B. Thompson et al. Nucleus accumbens mGluR5-associated signaling regulates binge alcohol drinking under drinking-in-the-dark procedures Alcohol Clin Exp Res 36 9 2012 1623 1633
    • (2012) Alcohol Clin Exp Res , vol.36 , Issue.9 , pp. 1623-1633
    • Cozzoli, D.K.1    Courson, J.2    Caruana, A.L.3    Miller, B.W.4    Greentree, D.I.5    Thompson, A.B.6
  • 87
    • 0036176446 scopus 로고    scopus 로고
    • Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects
    • DOI 10.1038/sj/mp/4000966
    • J.M. Crook, M. Akil, B.C. Law, T.M. Hyde, and J.E. Kleinman Comparative analysis of group II metabotropic glutamate receptor immunoreactivity in Brodmann's area 46 of the dorsolateral prefrontal cortex from patients with schizophrenia and normal subjects Mol Psychiatry 7 2 2002 157 164 (Pubitemid 34177783)
    • (2002) Molecular Psychiatry , vol.7 , Issue.2 , pp. 157-164
    • Crook, J.M.1    Akil, M.2    Law, B.C.W.3    Hyde, T.M.4    Kleinman, J.E.5
  • 88
    • 0022918964 scopus 로고
    • 3H]APB binding
    • S.L. Crooks, M.B. Robinson, J.F. Koerner, and R.L. Johnson Cyclic analogues of 2-amino-4-phosphonobutanoic acid (APB) and their inhibition of hippocampal excitatory transmission and displacement of [3H]APB binding J Med Chem 29 10 1986 1988 1995 (Pubitemid 16030306)
    • (1986) Journal of Medicinal Chemistry , vol.29 , Issue.10 , pp. 1988-1995
    • Crooks, S.L.1    Robinson, M.B.2    Koerner, J.F.3    Johnson, R.L.4
  • 89
    • 0038391169 scopus 로고    scopus 로고
    • Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7
    • DOI 10.1046/j.1460-9568.2003.02667.x
    • J.F. Cryan, P.H. Kelly, H.C. Neijt, G. Sansig, P.J. Flor, and H. van Der Putten Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7 Eur J Neurosci 17 11 2003 2409 2417 (Pubitemid 36793749)
    • (2003) European Journal of Neuroscience , vol.17 , Issue.11 , pp. 2409-2417
    • Cryan, J.F.1    Kelly, P.H.2    Neijt, H.C.3    Sansig, G.4    Flor, P.J.5    Van Der Putten, H.6
  • 90
    • 65649107339 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: Implications for Parkinson's disease treatment
    • D. Cuomo, G. Martella, E. Barabino, P. Platania, D. Vita, and G. Madeo et al. Metabotropic glutamate receptor subtype 4 selectively modulates both glutamate and GABA transmission in the striatum: implications for Parkinson's disease treatment J Neurochem 109 4 2009 1096 1105
    • (2009) J Neurochem , vol.109 , Issue.4 , pp. 1096-1105
    • Cuomo, D.1    Martella, G.2    Barabino, E.3    Platania, P.4    Vita, D.5    Madeo, G.6
  • 91
    • 84855890692 scopus 로고    scopus 로고
    • Measures of anxiety, sensorimotor function, and memory in male and female mGluR4(-)/(-) mice
    • M.J. Davis, T. Haley, R.M. Duvoisin, and J. Raber Measures of anxiety, sensorimotor function, and memory in male and female mGluR4(-)/(-) mice Behav Brain Res 229 1 2012 21 28
    • (2012) Behav Brain Res , vol.229 , Issue.1 , pp. 21-28
    • Davis, M.J.1    Haley, T.2    Duvoisin, R.M.3    Raber, J.4
  • 92
    • 33744801125 scopus 로고    scopus 로고
    • Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes
    • DOI 10.1021/jm051252j
    • T. de Paulis, K. Hemstapat, Y. Chen, Y. Zhang, S. Saleh, and D. Alagille et al. Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes J Med Chem 49 11 2006 3332 3344 (Pubitemid 43830531)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.11 , pp. 3332-3344
    • De Paulis, T.1    Hemstapat, K.2    Chen, Y.3    Zhang, Y.4    Saleh, S.5    Alagille, D.6    Baldwin, R.M.7    Tamagnan, G.D.8    Conn, P.J.9
  • 93
    • 33646812582 scopus 로고    scopus 로고
    • Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis
    • DOI 10.1016/j.pharmthera.2005.01.008, PII S016372580600009X
    • G.K. Dhami, and S.S. Ferguson Regulation of metabotropic glutamate receptor signaling, desensitization and endocytosis Pharmacol Ther 111 1 2006 260 271 (Pubitemid 43765534)
    • (2006) Pharmacology and Therapeutics , vol.111 , Issue.1 , pp. 260-271
    • Dhami, G.K.1    Ferguson, S.S.G.2
  • 94
    • 0033781704 scopus 로고    scopus 로고
    • A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices
    • A.J. Doherty, M.J. Palmer, Z.A. Bortolotto, A. Hargreaves, A.E. Kingston, and P.L. Ornstein et al. A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices Br J Pharmacol 131 2 2000 239 244
    • (2000) Br J Pharmacol , vol.131 , Issue.2 , pp. 239-244
    • Doherty, A.J.1    Palmer, M.J.2    Bortolotto, Z.A.3    Hargreaves, A.4    Kingston, A.E.5    Ornstein, P.L.6
  • 95
    • 0030894148 scopus 로고    scopus 로고
    • 1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus
    • DOI 10.1016/S0028-3908(97)00001-4, PII S0028390897000014
    • A.J. Doherty, M.J. Palmer, J.M. Henley, G.L. Collingridge, and D.E. Jane (RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus Neuropharmacology 36 2 1997 265 267 (Pubitemid 27149516)
    • (1997) Neuropharmacology , vol.36 , Issue.2 , pp. 265-267
    • Doherty, A.J.1    Palmer, M.J.2    Henley, J.M.3    Collingridge, G.L.4    Jane, D.E.5
  • 96
    • 20844441772 scopus 로고    scopus 로고
    • Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: Identification of a subtype selective mGlu2 receptor agonist
    • DOI 10.1021/jm040222y
    • C. Dominguez, L. Prieto, M.J. Valli, S.M. Massey, M. Bures, and R.A. Wright et al. Methyl substitution of 2-aminobicyclo[3.1.0]hexane 2,6-dicarboxylate (LY354740) determines functional activity at metabotropic glutamate receptors: identification of a subtype selective mGlu2 receptor agonist J Med Chem 48 10 2005 3605 3612 (Pubitemid 40664108)
    • (2005) Journal of Medicinal Chemistry , vol.48 , Issue.10 , pp. 3605-3612
    • Dominguez, C.1    Prieto, L.2    Valli, M.J.3    Massey, S.M.4    Bures, M.5    Wright, R.A.6    Johnson, B.G.7    Andis, S.L.8    Kingston, A.9    Schoepp, D.D.10    Monn, J.A.11
  • 97
    • 79251591614 scopus 로고    scopus 로고
    • A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors
    • E. Doumazane, P. Scholler, J.M. Zwier, E. Trinquet, P. Rondard, and J.P. Pin A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors FASEB J 25 1 2011 66 77
    • (2011) FASEB J , vol.25 , Issue.1 , pp. 66-77
    • Doumazane, E.1    Scholler, P.2    Zwier, J.M.3    Trinquet, E.4    Rondard, P.5    Pin, J.P.6
  • 98
    • 33846292496 scopus 로고    scopus 로고
    • MGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats
    • DOI 10.1016/j.neuropharm.2006.07.023, PII S0028390806002322
    • O.A. Dravolina, E.S. Zakharova, E.V. Shekunova, E.E. Zvartau, W. Danysz, and A.Y. Bespalov mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats Neuropharmacology 52 2 2007 263 269 (Pubitemid 46123346)
    • (2007) Neuropharmacology , vol.52 , Issue.2 , pp. 263-269
    • Dravolina, O.A.1    Zakharova, E.S.2    Shekunova, E.V.3    Zvartau, E.E.4    Danysz, W.5    Bespalov, A.Y.6
  • 99
    • 77954330278 scopus 로고    scopus 로고
    • Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease
    • S. Duty Therapeutic potential of targeting group III metabotropic glutamate receptors in the treatment of Parkinson's disease Br J Pharmacol 161 2 2010 271 287
    • (2010) Br J Pharmacol , vol.161 , Issue.2 , pp. 271-287
    • Duty, S.1
  • 100
    • 79952840690 scopus 로고    scopus 로고
    • Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges
    • R.M. Duvoisin, L. Villasana, M.J. Davis, D.G. Winder, and J. Raber Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges Behav Brain Res 221 1 2011 50 54
    • (2011) Behav Brain Res , vol.221 , Issue.1 , pp. 50-54
    • Duvoisin, R.M.1    Villasana, L.2    Davis, M.J.3    Winder, D.G.4    Raber, J.5
  • 101
    • 23244444497 scopus 로고    scopus 로고
    • Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8
    • DOI 10.1111/j.1460-9568.2005.04210.x
    • R.M. Duvoisin, C. Zhang, T.F. Pfankuch, H. O'Connor, J. Gayet-Primo, and S. Quraishi et al. Increased measures of anxiety and weight gain in mice lacking the group III metabotropic glutamate receptor mGluR8 Eur J Neurosci 22 2 2005 425 436 (Pubitemid 41097616)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.2 , pp. 425-436
    • Duvoisin, R.M.1    Zhang, C.2    Pfankuch, T.F.3    O'Connor, H.4    Gayet-Primo, J.5    Quraishi, S.6    Raber, J.7
  • 102
    • 77649149189 scopus 로고    scopus 로고
    • MGluR4 positive allosteric modulators with potential for the treatment of Parkinson's disease: WO09010455
    • S.P. East, and K. Gerlach mGluR4 positive allosteric modulators with potential for the treatment of Parkinson's disease: WO09010455 Expert Opin Ther Pat 20 3 2010 441 445
    • (2010) Expert Opin Ther Pat , vol.20 , Issue.3 , pp. 441-445
    • East, S.P.1    Gerlach, K.2
  • 103
    • 33846615765 scopus 로고    scopus 로고
    • The trick of the tail: Protein-protein interactions of metabotropic glutamate receptors
    • DOI 10.1002/bies.20518
    • R. Enz The trick of the tail: protein-protein interactions of metabotropic glutamate receptors Bioessays 29 1 2007 60 73 (Pubitemid 46181805)
    • (2007) BioEssays , vol.29 , Issue.1 , pp. 60-73
    • Enz, R.1
  • 104
    • 0025196959 scopus 로고
    • Metabolims and role of glutamate in mammalian brain
    • DOI 10.1016/0301-0082(90)90013-7
    • M. Erecinska, and I.A. Silver Metabolism and role of glutamate in mammalian brain Prog Neurobiol 35 4 1990 245 296 (Pubitemid 20304100)
    • (1990) Progress in Neurobiology , vol.35 , Issue.4 , pp. 245-296
    • Erecinska, M.1    Silver, I.A.2
  • 105
    • 84859999860 scopus 로고    scopus 로고
    • Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors
    • F. Fazio, L. Lionetto, G. Molinaro, H.O. Bertrand, F. Acher, and R.T. Ngomba et al. Cinnabarinic acid, an endogenous metabolite of the kynurenine pathway, activates type 4 metabotropic glutamate receptors Mol Pharmacol 81 5 2012 643 656
    • (2012) Mol Pharmacol , vol.81 , Issue.5 , pp. 643-656
    • Fazio, F.1    Lionetto, L.2    Molinaro, G.3    Bertrand, H.O.4    Acher, F.5    Ngomba, R.T.6
  • 106
    • 0035996546 scopus 로고    scopus 로고
    • The selective group mGlu2/3 receptor agonist LY379268 suppresses REM sleep and fast EEG in the rat
    • DOI 10.1016/S0091-3057(02)00843-2, PII S0091305702008432
    • I. Feinberg, I.G. Campbell, D.D. Schoepp, and K. Anderson The selective group mGlu2/3 receptor agonist LY379268 suppresses REM sleep and fast EEG in the rat Pharmacol Biochem Behav 73 2 2002 467 474 (Pubitemid 34765584)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.2 , pp. 467-474
    • Feinberg, I.1    Campbell, I.G.2    Schoepp, D.D.3    Anderson, K.4
  • 107
    • 51949091269 scopus 로고    scopus 로고
    • MGluR7 facilitates extinction of aversive memories and controls amygdala plasticity
    • M. Fendt, S. Schmid, D.R. Thakker, L.H. Jacobson, R. Yamamoto, and K. Mitsukawa et al. mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity Mol Psychiatry 13 10 2008 970 979
    • (2008) Mol Psychiatry , vol.13 , Issue.10 , pp. 970-979
    • Fendt, M.1    Schmid, S.2    Thakker, D.R.3    Jacobson, L.H.4    Yamamoto, R.5    Mitsukawa, K.6
  • 108
    • 58149101182 scopus 로고    scopus 로고
    • Metabotropic glutamate 1 receptor: Current concepts and perspectives
    • F. Ferraguti, L. Crepaldi, and F. Nicoletti Metabotropic glutamate 1 receptor: current concepts and perspectives Pharmacol Rev 60 4 2008 536 581
    • (2008) Pharmacol Rev , vol.60 , Issue.4 , pp. 536-581
    • Ferraguti, F.1    Crepaldi, L.2    Nicoletti, F.3
  • 110
    • 33748924690 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors
    • DOI 10.1007/s00441-006-0266-5
    • F. Ferraguti, and R. Shigemoto Metabotropic glutamate receptors Cell Tissue Res 326 2 2006 483 504 (Pubitemid 44435821)
    • (2006) Cell and Tissue Research , vol.326 , Issue.2 , pp. 483-504
    • Ferraguti, F.1    Shigemoto, R.2
  • 112
    • 0035996515 scopus 로고    scopus 로고
    • Antinociceptive effects following intrathecal pretreatment with selective metabotropic glutamate receptor compounds in a rat model of neuropathic pain
    • DOI 10.1016/S0091-3057(02)00832-8, PII S0091305702008328
    • K. Fisher, C. Lefebvre, and T.J. Coderre Antinociceptive effects following intrathecal pretreatment with selective metabotropic glutamate receptor compounds in a rat model of neuropathic pain Pharmacol Biochem Behav 73 2 2002 411 418 (Pubitemid 34765578)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.2 , pp. 411-418
    • Fisher, K.1    Lefebvre, C.2    Coderre, T.J.3
  • 113
    • 84864116271 scopus 로고    scopus 로고
    • Orthosteric versus allosteric GPCR activation: The great challenge of group-III mGluRs
    • P.J. Flor, and F.C. Acher Orthosteric versus allosteric GPCR activation: the great challenge of group-III mGluRs Biochem Pharmacol 84 4 2012 414 424
    • (2012) Biochem Pharmacol , vol.84 , Issue.4 , pp. 414-424
    • Flor, P.J.1    Acher, F.C.2
  • 115
    • 3843087453 scopus 로고    scopus 로고
    • A single In Vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens
    • DOI 10.1523/JNEUROSCI.0671-04.2004
    • L. Fourgeaud, S. Mato, D. Bouchet, A. Hemar, P.F. Worley, and O.J. Manzoni A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens J Neurosci 24 31 2004 6939 6945 (Pubitemid 39045451)
    • (2004) Journal of Neuroscience , vol.24 , Issue.31 , pp. 6939-6945
    • Fourgeaud, L.1    Mato, S.2    Bouchet, D.3    Hemar, A.4    Worley, P.F.5    Manzoni, O.J.6
  • 117
    • 79955485335 scopus 로고    scopus 로고
    • Density of metabotropic glutamate receptors 2 and 3 (mGluR2/3) in the dorsolateral prefrontal cortex does not differ with schizophrenia diagnosis but decreases with age
    • E. Frank, K.A. Newell, and X.F. Huang Density of metabotropic glutamate receptors 2 and 3 (mGluR2/3) in the dorsolateral prefrontal cortex does not differ with schizophrenia diagnosis but decreases with age Schizophr Res 128 1-3 2011 56 60
    • (2011) Schizophr Res , vol.128 , Issue.13 , pp. 56-60
    • Frank, E.1    Newell, K.A.2    Huang, X.F.3
  • 118
    • 0842324775 scopus 로고    scopus 로고
    • VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate
    • DOI 10.1016/j.tins.2003.11.005
    • R.T. Fremeau Jr., S. Voglmaier, R.P. Seal, and R.H. Edwards VGLUTs define subsets of excitatory neurons and suggest novel roles for glutamate Trends Neurosci 27 2 2004 98 103 (Pubitemid 38167332)
    • (2004) Trends in Neurosciences , vol.27 , Issue.2 , pp. 98-103
    • Fremeau Jr., R.T.1    Voglmaier, S.2    Seal, R.P.3    Edwards, R.H.4
  • 119
    • 84871645476 scopus 로고    scopus 로고
    • Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]- N-methyl-4-[11C]methylb enzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain
    • M. Fujinaga, T. Yamasaki, J. Maeda, J. Yui, L. Xie, and Y. Nagai et al. Development of N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N- methyl-4-[11C]methylb enzamide for positron emission tomography imaging of metabotropic glutamate 1 receptor in monkey brain J Med Chem 55 24 2012 11042 11051
    • (2012) J Med Chem , vol.55 , Issue.24 , pp. 11042-11051
    • Fujinaga, M.1    Yamasaki, T.2    Maeda, J.3    Yui, J.4    Xie, L.5    Nagai, Y.6
  • 120
    • 33745227414 scopus 로고    scopus 로고
    • Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice
    • R. Galici, C.K. Jones, K. Hemstapat, Y. Nong, N.G. Echemendia, and L.C. Williams et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice J Pharmacol Exp Ther 318 1 2006 173 185
    • (2006) J Pharmacol Exp Ther , vol.318 , Issue.1 , pp. 173-185
    • Galici, R.1    Jones, C.K.2    Hemstapat, K.3    Nong, Y.4    Echemendia, N.G.5    Williams, L.C.6
  • 121
    • 33750841778 scopus 로고    scopus 로고
    • Glutamate and GABA receptors and transporters in the basal ganglia: What does their subsynaptic localization reveal about their function?
    • DOI 10.1016/j.neuroscience.2006.09.019, PII S0306452206012462
    • A. Galvan, M. Kuwajima, and Y. Smith Glutamate and GABA receptors and transporters in the basal ganglia: what does their subsynaptic localization reveal about their function? Neuroscience 143 2 2006 351 375 (Pubitemid 44716603)
    • (2006) Neuroscience , vol.143 , Issue.2 , pp. 351-375
    • Galvan, A.1    Kuwajima, M.2    Smith, Y.3
  • 123
    • 36849072543 scopus 로고    scopus 로고
    • Glutamatergic substrates of drug addiction and alcoholism
    • DOI 10.1016/j.bcp.2007.06.039, PII S0006295207004182, Addiction
    • J.T. Gass, and M.F. Olive Glutamatergic substrates of drug addiction and alcoholism Biochem Pharmacol 75 1 2008 218 265 (Pubitemid 350235390)
    • (2008) Biochemical Pharmacology , vol.75 , Issue.1 , pp. 218-265
    • Gass, J.T.1    Olive, M.F.2
  • 124
    • 62749122197 scopus 로고    scopus 로고
    • Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory
    • J.T. Gass, and M.F. Olive Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory Biol Psychiatry 65 8 2009 717 720
    • (2009) Biol Psychiatry , vol.65 , Issue.8 , pp. 717-720
    • Gass, J.T.1    Olive, M.F.2
  • 125
    • 59949088634 scopus 로고    scopus 로고
    • MGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats
    • J.T. Gass, M.P. Osborne, N.L. Watson, J.L. Brown, and M.F. Olive mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats Neuropsychopharmacology 34 4 2009 820 833
    • (2009) Neuropsychopharmacology , vol.34 , Issue.4 , pp. 820-833
    • Gass, J.T.1    Osborne, M.P.2    Watson, N.L.3    Brown, J.L.4    Olive, M.F.5
  • 126
    • 0028851850 scopus 로고
    • Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1
    • R.W. Gereau IV, and P.J. Conn Multiple presynaptic metabotropic glutamate receptors modulate excitatory and inhibitory synaptic transmission in hippocampal area CA1 J Neurosci 15 10 1995 6879 6889
    • (1995) J Neurosci , vol.15 , Issue.10 , pp. 6879-6889
    • Gereau, I.V.R.W.1    Conn, P.J.2
  • 127
    • 0036669437 scopus 로고    scopus 로고
    • Performance deficits of mGluR8 knockout mice in learning tasks: The effects of null mutation and the background genotype
    • DOI 10.1016/S0028-3908(02)00078-3, PII S0028390802000783
    • R. Gerlai, B. Adams, T. Fitch, S. Chaney, and M. Baez Performance deficits of mGluR8 knockout mice in learning tasks: the effects of null mutation and the background genotype Neuropharmacology 43 2 2002 235 249 (Pubitemid 35247612)
    • (2002) Neuropharmacology , vol.43 , Issue.2 , pp. 235-249
    • Gerlai, R.1    Adams, B.2    Fitch, T.3    Chaney, S.4    Baez, M.5
  • 128
    • 60349120666 scopus 로고    scopus 로고
    • Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period
    • M.B. Ghasemzadeh, C. Mueller, and P. Vasudevan Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period Neuroscience 159 1 2009 414 426
    • (2009) Neuroscience , vol.159 , Issue.1 , pp. 414-426
    • Ghasemzadeh, M.B.1    Mueller, C.2    Vasudevan, P.3
  • 129
    • 0032953647 scopus 로고    scopus 로고
    • Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment
    • DOI 10.1046/j.1471-4159.1999.0720157.x
    • M.B. Ghasemzadeh, L.C. Nelson, X.Y. Lu, and P.W. Kalivas Neuroadaptations in ionotropic and metabotropic glutamate receptor mRNA produced by cocaine treatment J Neurochem 72 1 1999 157 165 (Pubitemid 29013889)
    • (1999) Journal of Neurochemistry , vol.72 , Issue.1 , pp. 157-165
    • Ghasemzadeh, M.B.1    Nelson, L.C.2    Lu, X.-Y.3    Kalivas, P.W.4
  • 130
    • 80052443440 scopus 로고    scopus 로고
    • Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration
    • M.B. Ghasemzadeh, P. Vasudevan, C. Giles, A. Purgianto, C. Seubert, and J.R. Mantsch Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration Brain Res 1413 2011 60 71
    • (2011) Brain Res , vol.1413 , pp. 60-71
    • Ghasemzadeh, M.B.1    Vasudevan, P.2    Giles, C.3    Purgianto, A.4    Seubert, C.5    Mantsch, J.R.6
  • 131
    • 53949094531 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 2 and 3 gene expression in the human prefrontal cortex and mesencephalon in schizophrenia
    • S. Ghose, J.M. Crook, C.L. Bartus, T.G. Sherman, M.M. Herman, and T.M. Hyde et al. Metabotropic glutamate receptor 2 and 3 gene expression in the human
    • (2008) Int J Neurosci , vol.118 , Issue.11 , pp. 1609-1627
    • Ghose, S.1    Crook, J.M.2    Bartus, C.L.3    Sherman, T.G.4    Herman, M.M.5    Hyde, T.M.6
  • 132
    • 84866375222 scopus 로고    scopus 로고
    • In vitro characterisation of the novel positive allosteric modulators of the mGlu(5) receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat
    • G. Gilmour, L.M. Broad, K.A. Wafford, T. Britton, E.M. Colvin, and A. Fivush et al. In vitro characterisation of the novel positive allosteric modulators of the mGlu(5) receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat Neuropharmacology 64 2013 224 239
    • (2013) Neuropharmacology , vol.64 , pp. 224-239
    • Gilmour, G.1    Broad, L.M.2    Wafford, K.A.3    Britton, T.4    Colvin, E.M.5    Fivush, A.6
  • 133
    • 84876439267 scopus 로고    scopus 로고
    • Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation
    • C.D. Gipson, Y.M. Kupchik, H. Shen, K.J. Reissner, C.A. Thomas, and P.W. Kalivas Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation Neuron 77 5 2013 867 872
    • (2013) Neuron , vol.77 , Issue.5 , pp. 867-872
    • Gipson, C.D.1    Kupchik, Y.M.2    Shen, H.3    Reissner, K.J.4    Thomas, C.A.5    Kalivas, P.W.6
  • 137
    • 84857594561 scopus 로고    scopus 로고
    • A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential
    • C. Goudet, B. Vilar, T. Courtiol, T. Deltheil, T. Bessiron, and I. Brabet et al. A novel selective metabotropic glutamate receptor 4 agonist reveals new possibilities for developing subtype selective ligands with therapeutic potential FASEB J 26 4 2012 1682 1693
    • (2012) FASEB J , vol.26 , Issue.4 , pp. 1682-1693
    • Goudet, C.1    Vilar, B.2    Courtiol, T.3    Deltheil, T.4    Bessiron, T.5    Brabet, I.6
  • 138
    • 77249085779 scopus 로고    scopus 로고
    • Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease
    • B. Greco, S. Lopez, H. van der Putten, P.J. Flor, and M. Amalric Metabotropic glutamate 7 receptor subtype modulates motor symptoms in rodent models of Parkinson's disease J Pharmacol Exp Ther 332 3 2010 1064 1071
    • (2010) J Pharmacol Exp Ther , vol.332 , Issue.3 , pp. 1064-1071
    • Greco, B.1    Lopez, S.2    Van Der Putten, H.3    Flor, P.J.4    Amalric, M.5
  • 140
    • 22544449233 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia
    • DOI 10.1002/syn.20164
    • D.S. Gupta, R.E. McCullumsmith, M. Beneyto, V. Haroutunian, K.L. Davis, and J.H. Meador-Woodruff Metabotropic glutamate receptor protein expression in the prefrontal cortex and striatum in schizophrenia Synapse 57 3 2005 123 131 (Pubitemid 41023469)
    • (2005) Synapse , vol.57 , Issue.3 , pp. 123-131
    • Gupta, D.S.1    McCullumsmith, R.E.2    Beneyto, M.3    Haroutunian, V.4    Davis, K.L.5    Meador-Woodruff, J.H.6
  • 141
    • 54249140161 scopus 로고    scopus 로고
    • Acute effects of acamprosate and MPEP on ethanol drinking-in-The-dark in male C57BL/6J mice
    • T. Gupta, Y.M. Syed, A.A. Revis, S.A. Miller, M. Martinez, and K.A. Cohn et al. Acute effects of acamprosate and MPEP on ethanol drinking-in-the-dark in male C57BL/6J mice Alcohol Clin Exp Res 32 11 2008 1992 1998
    • (2008) Alcohol Clin Exp Res , vol.32 , Issue.11 , pp. 1992-1998
    • Gupta, T.1    Syed, Y.M.2    Revis, A.A.3    Miller, S.A.4    Martinez, M.5    Cohn, K.A.6
  • 142
    • 79955704109 scopus 로고    scopus 로고
    • MGluR7 genetics and alcohol: Intersection yields clues for addiction
    • B. Gyetvai, A. Simonyi, M. Oros, M. Saito, J. Smiley, and C. Vadasz mGluR7 genetics and alcohol: intersection yields clues for addiction Neurochem Res 36 6 2011 1087 1100
    • (2011) Neurochem Res , vol.36 , Issue.6 , pp. 1087-1100
    • Gyetvai, B.1    Simonyi, A.2    Oros, M.3    Saito, M.4    Smiley, J.5    Vadasz, C.6
  • 144
    • 77955688416 scopus 로고    scopus 로고
    • Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: Factor in the transition to dependence
    • Y. Hao, R. Martin-Fardon, and F. Weiss Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: factor in the transition to dependence Biol Psychiatry 68 3 2010 240 248
    • (2010) Biol Psychiatry , vol.68 , Issue.3 , pp. 240-248
    • Hao, Y.1    Martin-Fardon, R.2    Weiss, F.3
  • 145
    • 39449104625 scopus 로고    scopus 로고
    • The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): Expression, function and involvement in schizophrenia
    • DOI 10.1177/0269881108089818
    • P.J. Harrison, L. Lyon, L.J. Sartorius, P.W. Burnet, and T.A. Lane The group II metabotropic glutamate receptor 3 (mGluR3, mGlu3, GRM3): expression, function and involvement in schizophrenia J Psychopharmacol 22 3 2008 308 322 (Pubitemid 351847454)
    • (2008) Journal of Psychopharmacology , vol.22 , Issue.3 , pp. 308-322
    • Harrison, P.J.1    Lyon, L.2    Sartorius, L.J.3    Burnet, P.W.J.4    Lane, T.A.5
  • 147
    • 0031011055 scopus 로고    scopus 로고
    • The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6
    • DOI 10.1111/j.1460-9568.1997.tb01477.x
    • T. Hashimoto, J. Inazawa, N. Okamoto, Y. Tagawa, Y. Bessho, and Y. Honda et al. The whole nucleotide sequence and chromosomal localization of the gene for human metabotropic glutamate receptor subtype 6 Eur J Neurosci 9 6 1997 1226 1235 (Pubitemid 27260751)
    • (1997) European Journal of Neuroscience , vol.9 , Issue.6 , pp. 1226-1235
    • Hashimoto, T.1
  • 148
    • 84881313914 scopus 로고    scopus 로고
    • Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders
    • K. Hashimoto, B. Malchow, P. Falkai, and A. Schmitt Glutamate modulators as potential therapeutic drugs in schizophrenia and affective disorders Eur Arch Psychiatry Clin Neurosci 263 5 2013 367 377
    • (2013) Eur Arch Psychiatry Clin Neurosci , vol.263 , Issue.5 , pp. 367-377
    • Hashimoto, K.1    Malchow, B.2    Falkai, P.3    Schmitt, A.4
  • 149
    • 0031406508 scopus 로고    scopus 로고
    • LY354740: A metabotropic glutamate receptor agonist which ameliorates symptoms of nicotine withdrawal in rats
    • DOI 10.1016/S0028-3908(97)00170-6, PII S0028390897001706
    • D.R. Helton, J.P. Tizzano, J.A. Monn, D.D. Schoepp, and M.J. Kallman LY354740: a metabotropic glutamate receptor agonist which ameliorates symptoms of nicotine withdrawal in rats Neuropharmacology 36 11-12 1997 1511 1516 (Pubitemid 28085910)
    • (1997) Neuropharmacology , vol.36 , Issue.11-12 , pp. 1511-1516
    • Helton, D.R.1    Tizzano, J.P.2    Monn, J.A.3    Schoepp, D.D.4    Kallman, M.J.5
  • 151
    • 84878842131 scopus 로고    scopus 로고
    • MGluR5 is necessary for maintenance of methamphetamine-induced associative learning
    • A.A. Herrold, R.M. Voigt, and T.C. Napier mGluR5 is necessary for maintenance of methamphetamine-induced associative learning Eur Neuropsychopharmacol 23 7 2013 691 696
    • (2013) Eur Neuropsychopharmacol , vol.23 , Issue.7 , pp. 691-696
    • Herrold, A.A.1    Voigt, R.M.2    Napier, T.C.3
  • 152
    • 24944590000 scopus 로고    scopus 로고
    • Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats
    • DOI 10.1080/13556210500223272
    • V. Herzig, E.M. Capuani, K.A. Kovar, and W.J. Schmidt Effects of MPEP on expression of food-, MDMA- or amphetamine-conditioned place preference in rats Addict Biol 10 3 2005 243 249 (Pubitemid 41306327)
    • (2005) Addiction Biology , vol.10 , Issue.3 , pp. 243-249
    • Herzig, V.1    Capuani, E.M.I.2    Kovar, K.-A.3    Schmidt, W.J.4
  • 153
    • 8844238423 scopus 로고    scopus 로고
    • Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine
    • DOI 10.1016/j.neuropharm.2004.07.037, PII S0028390804002345
    • V. Herzig, and W.J. Schmidt Effects of MPEP on locomotion, sensitization and conditioned reward induced by cocaine or morphine Neuropharmacology 47 7 2004 973 984 (Pubitemid 39535838)
    • (2004) Neuropharmacology , vol.47 , Issue.7 , pp. 973-984
    • Herzig, V.1    Schmidt, W.J.2
  • 156
    • 28344451556 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice
    • DOI 10.1007/s00213-005-0217-y
    • C.W. Hodge, M.F. Miles, A.C. Sharko, R.A. Stevenson, J.R. Hillmann, and V. Lepoutre et al. The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice Psychopharmacology (Berl) 183 4 2006 429 438 (Pubitemid 41721144)
    • (2006) Psychopharmacology , vol.183 , Issue.4 , pp. 429-438
    • Hodge, C.W.1    Miles, M.F.2    Sharko, A.C.3    Stevenson, R.A.4    Hillmann, J.R.5    Lepoutre, V.6    Besheer, J.7    Schroeder, J.P.8
  • 157
    • 4143099070 scopus 로고    scopus 로고
    • Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory
    • DOI 10.1016/j.bbr.2004.03.015, PII S0166432804001111
    • C. Holscher, S. Schmid, P.K. Pilz, G. Sansig, H. van der Putten, and C.F. Plappert Lack of the metabotropic glutamate receptor subtype 7 selectively impairs short-term working memory but not long-term memory Behav Brain Res 154 2 2004 473 481 (Pubitemid 39093998)
    • (2004) Behavioural Brain Research , vol.154 , Issue.2 , pp. 473-481
    • Holscher, C.1    Schmid, S.2    Pilz, P.K.D.3    Sansig, G.4    Van Der Putten, H.5    Plappert, C.F.6
  • 158
    • 79960627268 scopus 로고    scopus 로고
    • Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators
    • S. Hong, K.G. Liu, G. Ma, M. Sabio, M.A. Uberti, and M.D. Bacolod et al. Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators J Med Chem 54 14 2011 5070 5081
    • (2011) J Med Chem , vol.54 , Issue.14 , pp. 5070-5081
    • Hong, S.1    Liu, K.G.2    Ma, G.3    Sabio, M.4    Uberti, M.A.5    Bacolod, M.D.6
  • 159
    • 78649996218 scopus 로고    scopus 로고
    • Synthesis, characterization, and monkey PET studies of [(1)(8)F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435
    • E.D. Hostetler, W. Eng, A.D. Joshi, S. Sanabria-Bohorquez, H. Kawamoto, and S. Ito et al. Synthesis, characterization, and monkey PET studies of [(1)(8)F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435 Synapse 65 2 2011 125 135
    • (2011) Synapse , vol.65 , Issue.2 , pp. 125-135
    • Hostetler, E.D.1    Eng, W.2    Joshi, A.D.3    Sanabria-Bohorquez, S.4    Kawamoto, H.5    Ito, S.6
  • 160
    • 79952761620 scopus 로고    scopus 로고
    • Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens
    • C.C. Huang, C.M. Yeh, M.Y. Wu, A.Y. Chang, J.Y. Chan, and S.H. Chan et al. Cocaine withdrawal impairs metabotropic glutamate receptor-dependent long-term depression in the nucleus accumbens J Neurosci 31 11 2011 4194 4203
    • (2011) J Neurosci , vol.31 , Issue.11 , pp. 4194-4203
    • Huang, C.C.1    Yeh, C.M.2    Wu, M.Y.3    Chang, A.Y.4    Chan, J.Y.5    Chan, S.H.6
  • 162
    • 32344445040 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationships of 3-[(2-methyl-1,3- thiazol- 4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications
    • DOI 10.1021/jm050570f
    • Y. Iso, E. Grajkowska, J.T. Wroblewski, J. Davis, N.E. Goeders, and K.M. Johnson et al. Synthesis and structure-activity relationships of 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine analogues as potent, noncompetitive metabotropic glutamate receptor subtype 5 antagonists; search for cocaine medications J Med Chem 49 3 2006 1080 1100 (Pubitemid 43221655)
    • (2006) Journal of Medicinal Chemistry , vol.49 , Issue.3 , pp. 1080-1100
    • Iso, Y.1    Grajkowska, E.2    Wroblewski, J.T.3    Davis, J.4    Goeders, N.E.5    Johnson, K.M.6    Sanker, S.7    Roth, B.L.8    Tueckmantel, W.9    Kozikowski, A.P.10
  • 163
    • 0030941005 scopus 로고    scopus 로고
    • Impairment of pupillary responses and optokinetic nystagmus in the mGluR6-deficient mouse
    • DOI 10.1016/S0028-3908(96)00167-0, PII S0028390896001670
    • H. Iwakabe, G. Katsuura, C. Ishibashi, and S. Nakanishi Impairment of pupillary responses and optokinetic nystagmus in the mGluR6-deficient mouse Neuropharmacology 36 2 1997 135 143 (Pubitemid 27149501)
    • (1997) Neuropharmacology , vol.36 , Issue.2 , pp. 135-143
    • Iwakabe, H.1    Katsuura, G.2    Ishibashi, C.3    Nakanishi, S.4
  • 164
    • 0028245013 scopus 로고
    • Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord
    • D.E. Jane, P.L. Jones, P.C. Pook, H.W. Tse, and J.C. Watkins Actions of two new antagonists showing selectivity for different sub-types of metabotropic glutamate receptor in the neonatal rat spinal cord Br J Pharmacol 112 3 1994 809 816 (Pubitemid 24199087)
    • (1994) British Journal of Pharmacology , vol.112 , Issue.3 , pp. 809-816
    • Jane, D.E.1    Jones, P.L.S.J.2    Pook, P.C.-K.3    Tse, H.-W.4    Watkins, J.C.5
  • 165
    • 34447293737 scopus 로고    scopus 로고
    • Long-Term Depression of mGluR1 Signaling
    • DOI 10.1016/j.neuron.2007.06.035, PII S0896627307004928
    • Y. Jin, S.J. Kim, J. Kim, P.F. Worley, and D.J. Linden Long-term depression of mGluR1 signaling Neuron 55 2 2007 277 287 (Pubitemid 47048914)
    • (2007) Neuron , vol.55 , Issue.2 , pp. 277-287
    • Jin, Y.1    Kim, S.J.2    Kim, J.3    Worley, P.F.4    Linden, D.J.5
  • 166
    • 77955717226 scopus 로고    scopus 로고
    • The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats
    • X. Jin, S. Semenova, L. Yang, R. Ardecky, D.J. Sheffler, and R. Dahl et al. The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats Neuropsychopharmacology 35 10 2010 2021 2036
    • (2010) Neuropsychopharmacology , vol.35 , Issue.10 , pp. 2021-2036
    • Jin, X.1    Semenova, S.2    Yang, L.3    Ardecky, R.4    Sheffler, D.J.5    Dahl, R.6
  • 167
    • 20944447548 scopus 로고    scopus 로고
    • Metabotropic glutamate 2 receptor potentiators: Receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)
    • DOI 10.1007/s00213-004-2099-9
    • M.P. Johnson, D. Barda, T.C. Britton, R. Emkey, W.J. Hornback, and G.E. Jagdmann et al. Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s) Psychopharmacology (Berl) 179 1 2005 271 283 (Pubitemid 40576715)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 271-283
    • Johnson, M.P.1    Barda, D.2    Britton, T.C.3    Emkey, R.4    Hornback, W.J.5    Jagdmann, G.E.6    McKinzie, D.L.7    Nisenbaum, E.S.8    Tizzano, J.P.9    Schoepp, D.D.10
  • 168
    • 0033550927 scopus 로고    scopus 로고
    • Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists
    • DOI 10.1016/S0006-8993(99)01065-3, PII S0006899399010653
    • M.P. Johnson, M. Chamberlain, and G.M. Kelly Phosphoinositide hydrolysis in vivo with group I metabotropic glutamate receptor agonists Brain Res 821 2 1999 539 545 (Pubitemid 29222821)
    • (1999) Brain Research , vol.821 , Issue.2 , pp. 539-545
    • Johnson, M.P.1    Chamberlain, M.2    Kelly, G.M.3
  • 169
    • 84856022448 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with l-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease
    • C.K. Jones, M. Bubser, A.D. Thompson, J.W. Dickerson, N. Turle-Lorenzo, and M. Amalric et al. The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with l-DOPA or an adenosine 2A antagonist in preclinical rodent models of Parkinson's disease J Pharmacol Exp Ther 340 2 2012 404 421
    • (2012) J Pharmacol Exp Ther , vol.340 , Issue.2 , pp. 404-421
    • Jones, C.K.1    Bubser, M.2    Thompson, A.D.3    Dickerson, J.W.4    Turle-Lorenzo, N.5    Amalric, M.6
  • 170
    • 49949112373 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors mGluR4 and mGluR8 regulate transmission in the lateral olfactory tract-piriform cortex synapse
    • P.J. Jones, Z. Xiang, and P.J. Conn Metabotropic glutamate receptors mGluR4 and mGluR8 regulate transmission in the lateral olfactory tract-piriform cortex synapse Neuropharmacology 55 4 2008 440 446
    • (2008) Neuropharmacology , vol.55 , Issue.4 , pp. 440-446
    • Jones, P.J.1    Xiang, Z.2    Conn, P.J.3
  • 171
    • 24044447233 scopus 로고    scopus 로고
    • Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons: Role of transporters in delivering ligand
    • DOI 10.1074/jbc.M501775200
    • Y.J. Jong, V. Kumar, A.E. Kingston, C. Romano, and K.L. O'Malley Functional metabotropic glutamate receptors on nuclei from brain and primary cultured striatal neurons. Role of transporters in delivering ligand J Biol Chem 280 34 2005 30469 30480 (Pubitemid 41216231)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.34 , pp. 30469-30480
    • Jong, Y.-J.I.1    Kumar, V.2    Kingston, A.E.3    Romano, C.4    O'Malley, K.L.5
  • 172
    • 84879702095 scopus 로고    scopus 로고
    • A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 - Estimating occupancy in the absence of a reference region
    • M. Kagedal, Z. Cselenyi, S. Nyberg, P. Raboisson, L. Stahle, and P. Stenkrona et al. A positron emission tomography study in healthy volunteers to estimate mGluR5 receptor occupancy of AZD2066 - Estimating occupancy in the absence of a reference region Neuroimage 82 2013 160 169
    • (2013) Neuroimage , vol.82 , pp. 160-169
    • Kagedal, M.1    Cselenyi, Z.2    Nyberg, S.3    Raboisson, P.4    Stahle, L.5    Stenkrona, P.6
  • 173
    • 0035966145 scopus 로고    scopus 로고
    • Group 2 metabotropic glutamate receptors induced long term depression in mouse striatal slices
    • DOI 10.1016/S0304-3940(01)02397-7, PII S0304394001023977
    • L. Kahn, G. Alonso, D. Robbe, J. Bockaert, and O.J. Manzoni Group 2 metabotropic glutamate receptors induced long term depression in mouse striatal slices Neurosci Lett 316 3 2001 178 182 (Pubitemid 34020758)
    • (2001) Neuroscience Letters , vol.316 , Issue.3 , pp. 178-182
    • Kahn, L.1    Alonso, G.2    Robbe, D.3    Bockaert, J.4    Manzoni, O.J.5
  • 174
    • 0742323783 scopus 로고    scopus 로고
    • Glutamate systems in cocaine addiction
    • DOI 10.1016/j.coph.2003.11.002, PII S1471489203002042
    • P.W. Kalivas Glutamate systems in cocaine addiction Curr Opin Pharmacol 4 1 2004 23 29 (Pubitemid 38145834)
    • (2004) Current Opinion in Pharmacology , vol.4 , Issue.1 , pp. 23-29
    • Kalivas, P.W.1
  • 175
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • P.W. Kalivas The glutamate homeostasis hypothesis of addiction Nat Rev Neurosci 10 8 2009 561 572
    • (2009) Nat Rev Neurosci , vol.10 , Issue.8 , pp. 561-572
    • Kalivas, P.W.1
  • 176
    • 35948936012 scopus 로고    scopus 로고
    • Effect of 2-methyl-6-(phenylethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat
    • DOI 10.1097/FBP.0b013e3282f18d58, PII 0000887720071200000002
    • E.L.v.d. Kam, J.d. Vry, and T.M. Tzschentke Effect of 2-methyl-6-(phenylethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat Behav Pharmacol 18 8 2007 717 724 (Pubitemid 350076428)
    • (2007) Behavioural Pharmacology , vol.18 , Issue.8 , pp. 717-724
    • Van Der Kam, E.L.1    De Vry, J.2    Tzschentke, T.M.3
  • 177
    • 61449163739 scopus 로고    scopus 로고
    • 2-Methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates ketamine and heroin reward as assessed by acquisition, extinction, and reinstatement of conditioned place preference in the rat
    • E.L.v.d. Kam, J.D. Vry, and T.M. Tzschentke 2-Methyl-6-(phenylethynyl)- pyridine (MPEP) potentiates ketamine and heroin reward as assessed by acquisition, extinction, and reinstatement of conditioned place preference in the rat Eur J Pharmacol 606 1-3 2009 94 101
    • (2009) Eur J Pharmacol , vol.606 , Issue.13 , pp. 94-101
    • Kam, E.L.V.D.1    Vry, J.D.2    Tzschentke, T.M.3
  • 178
    • 62549140970 scopus 로고    scopus 로고
    • The mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) supports intravenous self-administration and induces conditioned place preference in the rat
    • E.L.v.d. Kam, J.D. Vry, and T.M. Tzschentke The mGlu5 receptor antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) supports intravenous self-administration and induces conditioned place preference in the rat Eur J Pharmacol 607 1-3 2009 114 120
    • (2009) Eur J Pharmacol , vol.607 , Issue.13 , pp. 114-120
    • Kam, E.L.V.D.1    Vry, J.D.2    Tzschentke, T.M.3
  • 179
    • 51649103854 scopus 로고    scopus 로고
    • Endogenous homer proteins regulate metabotropic glutamate receptor signaling in neurons
    • P.J. Kammermeier Endogenous homer proteins regulate metabotropic glutamate receptor signaling in neurons J Neurosci 28 34 2008 8560 8567
    • (2008) J Neurosci , vol.28 , Issue.34 , pp. 8560-8567
    • Kammermeier, P.J.1
  • 180
    • 84865263040 scopus 로고    scopus 로고
    • Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers
    • P.J. Kammermeier Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers Mol Pharmacol 82 3 2012 438 447
    • (2012) Mol Pharmacol , vol.82 , Issue.3 , pp. 438-447
    • Kammermeier, P.J.1
  • 181
    • 78650815511 scopus 로고    scopus 로고
    • Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice
    • T. Kawasaki, Y. Ago, K. Yano, R. Araki, Y. Washida, and H. Onoe et al. Increased binding of cortical and hippocampal group II metabotropic glutamate receptors in isolation-reared mice Neuropharmacology 60 2-3 2011 397 404
    • (2011) Neuropharmacology , vol.60 , Issue.23 , pp. 397-404
    • Kawasaki, T.1    Ago, Y.2    Yano, K.3    Araki, R.4    Washida, Y.5    Onoe, H.6
  • 182
    • 84883452045 scopus 로고    scopus 로고
    • Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: Implications for addiction treatment in humans
    • T.M. Keck, H.J. Yang, G.H. Bi, Y. Huang, H.Y. Zhang, and R. Srivastava et al. Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans Psychopharmacology (Berl) 229 2 2013 253 265
    • (2013) Psychopharmacology (Berl) , vol.229 , Issue.2 , pp. 253-265
    • Keck, T.M.1    Yang, H.J.2    Bi, G.H.3    Huang, Y.4    Zhang, H.Y.5    Srivastava, R.6
  • 183
    • 84863844394 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 negative allosteric modulators as novel tools for in vivo investigation
    • T.M. Keck, M.F. Zou, P. Zhang, R.P. Rutledge, and A.H. Newman Metabotropic glutamate receptor 5 negative allosteric modulators as novel tools for in vivo investigation ACS Bioorg Med Chem Lett 3 7 2012 544 549
    • (2012) ACS Bioorg Med Chem Lett , vol.3 , Issue.7 , pp. 544-549
    • Keck, T.M.1    Zou, M.F.2    Zhang, P.3    Rutledge, R.P.4    Newman, A.H.5
  • 184
    • 33847228347 scopus 로고    scopus 로고
    • Hippocampal long-term depression: Master or minion in declarative memory processes?
    • A. Kemp, and D. Manahan-Vaughan Hippocampal long-term depression: master or minion in declarative memory processes? Trends Neurosci 30 3 2007 111 118
    • (2007) Trends Neurosci , vol.30 , Issue.3 , pp. 111-118
    • Kemp, A.1    Manahan-Vaughan, D.2
  • 185
    • 17744400697 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats
    • DOI 10.1007/s00213-004-2069-2
    • P.J. Kenny, B. Boutrel, F. Gasparini, G.F. Koob, and A. Markou Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats Psychopharmacology (Berl) 179 1 2005 247 254 (Pubitemid 40576712)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 247-254
    • Kenny, P.J.1    Boutrel, B.2    Gasparini, F.3    Koob, G.F.4    Markou, A.5
  • 186
  • 187
    • 8844263762 scopus 로고    scopus 로고
    • Positive and negative allosteric modulation of metabotropic glutamate receptors: Emerging therapeutic potential
    • DOI 10.1016/j.pharmthera.2004.08.010, PII S0163725804001275
    • J.N. Kew Positive and negative allosteric modulation of metabotropic glutamate receptors: emerging therapeutic potential Pharmacol Ther 104 3 2004 233 244 (Pubitemid 39531928)
    • (2004) Pharmacology and Therapeutics , vol.104 , Issue.3 , pp. 233-244
    • Kew, J.N.C.1
  • 188
    • 17744387125 scopus 로고    scopus 로고
    • Ionotropic and metabotropic glutamate receptor structure and pharmacology
    • DOI 10.1007/s00213-005-2200-z
    • J.N. Kew, and J.A. Kemp Ionotropic and metabotropic glutamate receptor structure and pharmacology Psychopharmacology (Berl) 179 1 2005 4 29 (Pubitemid 40576690)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 4-29
    • Kew, J.N.C.1    Kemp, J.A.2
  • 189
    • 13244299341 scopus 로고    scopus 로고
    • Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine
    • DOI 10.1111/j.1460-9568.2004.03822.x
    • J.H. Kim, J.D. Austin, L. Tanabe, E. Creekmore, and P. Vezina Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine Eur J Neurosci 21 1 2005 295 300 (Pubitemid 40193900)
    • (2005) European Journal of Neuroscience , vol.21 , Issue.1 , pp. 295-300
    • Kim, J.-H.1    Austin, J.D.2    Tanabe, L.3    Creekmore, E.4    Vezina, P.5
  • 190
    • 38049084115 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors: Phosphorylation and receptor signaling
    • C.H. Kim, J. Lee, J.Y. Lee, and K.W. Roche Metabotropic glutamate receptors: phosphorylation and receptor signaling J Neurosci Res 86 1 2008 1 10
    • (2008) J Neurosci Res , vol.86 , Issue.1 , pp. 1-10
    • Kim, C.H.1    Lee, J.2    Lee, J.Y.3    Roche, K.W.4
  • 191
    • 0032513558 scopus 로고    scopus 로고
    • Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: A light and electron microscopic study
    • DOI 10.1002/(SICI)1096-9861(19980413)393: 3<332::AID-CNE6>3.0.CO;2- 2
    • A. Kinoshita, R. Shigemoto, H. Ohishi, H.v. d Putten, and N. Mizuno Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: a light and electron microscopic study J Comp Neurol 393 3 1998 332 352 (Pubitemid 28164590)
    • (1998) Journal of Comparative Neurology , vol.393 , Issue.3 , pp. 332-352
    • Kinoshita, A.1    Shigemoto, R.2    Ohishi, H.3    Van Der Putten, H.4    Mizuno, N.5
  • 192
    • 0037083370 scopus 로고    scopus 로고
    • Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins
    • J. Kitano, K. Kimura, Y. Yamazaki, T. Soda, R. Shigemoto, and Y. Nakajima et al. Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins J Neurosci 22 4 2002 1280 1289 (Pubitemid 34163730)
    • (2002) Journal of Neuroscience , vol.22 , Issue.4 , pp. 1280-1289
    • Kitano, J.1    Kimura, K.2    Yamazaki, Y.3    Soda, T.4    Shigemoto, R.5    Nakajima, Y.6    Nakanishi, S.7
  • 193
    • 0035996485 scopus 로고    scopus 로고
    • Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice
    • DOI 10.1016/S0091-3057(02)00845-6, PII S0091305702008456
    • A. Klodzinska, M. Bijak, K. Tokarski, and A. Pilc Group II mGlu receptor agonists inhibit behavioural and electrophysiological effects of DOI in mice Pharmacol Biochem Behav 73 2 2002 327 332 (Pubitemid 34765571)
    • (2002) Pharmacology Biochemistry and Behavior , vol.73 , Issue.2 , pp. 327-332
    • Klodzinska, A.1    Bijak, M.2    Tokarski, K.3    Pilc, A.4
  • 194
    • 0344980107 scopus 로고    scopus 로고
    • Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models
    • DOI 10.1016/S0028-3908(99)00066-0, PII S0028390899000660
    • A. Klodzinska, E. Chojnacka-Wojcik, A. Palucha, P. Branski, P. Popik, and A. Pilc Potential anti-anxiety, anti-addictive effects of LY 354740, a selective group II glutamate metabotropic receptors agonist in animal models Neuropharmacology 38 12 1999 1831 1839 (Pubitemid 29509721)
    • (1999) Neuropharmacology , vol.38 , Issue.12 , pp. 1831-1839
    • Klodzinska, A.1    Chojnacka-Wojcik, E.2    Palucha, A.3    Branski, P.4    Popik, P.5    Pilc, A.6
  • 196
    • 71349088692 scopus 로고    scopus 로고
    • Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking
    • L.A. Knackstedt, R.I. Melendez, and P.W. Kalivas Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking Biol Psychiatry 67 1 2010 81 84
    • (2010) Biol Psychiatry , vol.67 , Issue.1 , pp. 81-84
    • Knackstedt, L.A.1    Melendez, R.I.2    Kalivas, P.W.3
  • 197
    • 84890787469 scopus 로고    scopus 로고
    • The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning
    • L.A. Knackstedt, H.L. Trantham-Davidson, and M. Schwendt The role of ventral and dorsal striatum mGluR5 in relapse to cocaine-seeking and extinction learning Addict Biol 19 1 2014 87 101
    • (2014) Addict Biol , vol.19 , Issue.1 , pp. 87-101
    • Knackstedt, L.A.1    Trantham-Davidson, H.L.2    Schwendt, M.3
  • 199
    • 2942555610 scopus 로고    scopus 로고
    • Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat
    • DOI 10.1111/j.0953-816X.2004.03394.x
    • N. Kogo, Y. Dalezios, M. Capogna, F. Ferraguti, R. Shigemoto, and P. Somogyi Depression of GABAergic input to identified hippocampal neurons by group III metabotropic glutamate receptors in the rat Eur J Neurosci 19 10 2004 2727 2740 (Pubitemid 38746390)
    • (2004) European Journal of Neuroscience , vol.19 , Issue.10 , pp. 2727-2740
    • Kogo, N.1    Dalezios, Y.2    Capogna, M.3    Ferraguti, F.4    Shigemoto, R.5    Somogyi, P.6
  • 200
    • 34548037717 scopus 로고    scopus 로고
    • Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models
    • DOI 10.1016/j.ejphar.2007.05.030, PII S0014299907006425
    • A. Kohara, Y. Nagakura, T. Kiso, T. Toya, T. Watabiki, and S. Tamura et al. Antinociceptive profile of a selective metabotropic glutamate receptor 1 antagonist YM-230888 in chronic pain rodent models Eur J Pharmacol 571 1 2007 8 16 (Pubitemid 47284045)
    • (2007) European Journal of Pharmacology , vol.571 , Issue.1 , pp. 8-16
    • Kohara, A.1    Nagakura, Y.2    Kiso, T.3    Toya, T.4    Watabiki, T.5    Tamura, S.6    Shitaka, Y.7    Itahana, H.8    Okada, M.9
  • 201
    • 38349050158 scopus 로고    scopus 로고
    • Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models
    • A. Kohara, M. Takahashi, S. Yatsugi, S. Tamura, Y. Shitaka, and S. Hayashibe et al. Neuroprotective effects of the selective type 1 metabotropic glutamate receptor antagonist YM-202074 in rat stroke models Brain Res 1191 2008 168 179
    • (2008) Brain Res , vol.1191 , pp. 168-179
    • Kohara, A.1    Takahashi, M.2    Yatsugi, S.3    Tamura, S.4    Shitaka, Y.5    Hayashibe, S.6
  • 203
    • 78650575007 scopus 로고    scopus 로고
    • Pretreatment with group i metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice
    • J. Kotlinska, and M. Bochenski Pretreatment with group I metabotropic glutamate receptors antagonists attenuates lethality induced by acute cocaine overdose and expression of sensitization to hyperlocomotor effect of cocaine in mice Neurotox Res 19 1 2011 23 30
    • (2011) Neurotox Res , vol.19 , Issue.1 , pp. 23-30
    • Kotlinska, J.1    Bochenski, M.2
  • 204
    • 80054741157 scopus 로고    scopus 로고
    • The role of group i mGlu receptors in the expression of ethanol-induced conditioned place preference and ethanol withdrawal seizures in rats
    • J.H. Kotlinska, M. Bochenski, and W. Danysz The role of group I mGlu receptors in the expression of ethanol-induced conditioned place preference and ethanol withdrawal seizures in rats Eur J Pharmacol 670 1 2011 154 161
    • (2011) Eur J Pharmacol , vol.670 , Issue.1 , pp. 154-161
    • Kotlinska, J.H.1    Bochenski, M.2    Danysz, W.3
  • 205
    • 11144316721 scopus 로고    scopus 로고
    • Interaction between mGluR8 and calcium channels in photoreceptors is sensitive to pertussis toxin and occurs via G protein βγ subunit signaling
    • DOI 10.1167/iovs.04-0963
    • P. Koulen, J. Liu, E. Nixon, and C. Madry Interaction between mGluR8 and calcium channels in photoreceptors is sensitive to pertussis toxin and occurs via G protein betagamma subunit signaling Invest Ophthalmol Vis Sci 46 1 2005 287 291 (Pubitemid 40041209)
    • (2005) Investigative Ophthalmology and Visual Science , vol.46 , Issue.1 , pp. 287-291
    • Koulen, P.1    Liu, J.2    Nixon, E.3    Madry, C.4
  • 206
    • 77953299266 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain
    • N. Kumar, A. Laferriere, J.S. Yu, T. Poon, and T.J. Coderre Metabotropic glutamate receptors (mGluRs) regulate noxious stimulus-induced glutamate release in the spinal cord dorsal horn of rats with neuropathic and inflammatory pain J Neurochem 114 1 2010 281 290
    • (2010) J Neurochem , vol.114 , Issue.1 , pp. 281-290
    • Kumar, N.1    Laferriere, A.2    Yu, J.S.3    Poon, T.4    Coderre, T.J.5
  • 207
    • 65549145853 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking
    • V. Kumaresan, M. Yuan, J. Yee, K.R. Famous, S.M. Anderson, and H.D. Schmidt et al. Metabotropic glutamate receptor 5 (mGluR5) antagonists attenuate cocaine priming- and cue-induced reinstatement of cocaine seeking Behav Brain Res 202 2 2009 238 244
    • (2009) Behav Brain Res , vol.202 , Issue.2 , pp. 238-244
    • Kumaresan, V.1    Yuan, M.2    Yee, J.3    Famous, K.R.4    Anderson, S.M.5    Schmidt, H.D.6
  • 208
    • 42049118695 scopus 로고    scopus 로고
    • Therapeutic potential of group III metabotropic glutamate receptors
    • DOI 10.2174/092986708783885246
    • H. Lavreysen, and F.M. Dautzenberg Therapeutic potential of group III metabotropic glutamate receptors Curr Med Chem 15 7 2008 671 684 (Pubitemid 351516803)
    • (2008) Current Medicinal Chemistry , vol.15 , Issue.7 , pp. 671-684
    • Lavreysen, H.1    Dautzenberg, F.M.2
  • 209
    • 0037731410 scopus 로고    scopus 로고
    • 3H]R214127: A novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists
    • DOI 10.1124/mol.63.5.1082
    • H. Lavreysen, C. Janssen, F. Bischoff, X. Langlois, J.E. Leysen, and A.S. Lesage [3H]R214127: a novel high-affinity radioligand for the mGlu1 receptor reveals a common binding site shared by multiple allosteric antagonists Mol Pharmacol 63 5 2003 1082 1093 (Pubitemid 36529927)
    • (2003) Molecular Pharmacology , vol.63 , Issue.5 , pp. 1082-1093
    • Lavreysen, H.1    Janssen, C.2    Bischoff, F.3    Langlois, X.4    Leysen, J.E.5    Lesage, A.S.J.6
  • 210
    • 14344261021 scopus 로고    scopus 로고
    • Attenuation of behavioral effects of cocaine by the metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: Comparison with dizocilpine
    • DOI 10.1124/jpet.104.078733
    • B. Lee, D.M. Platt, J.K. Rowlett, A.S. Adewale, and R.D. Spealman Attenuation of behavioral effects of cocaine by the metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: comparison with dizocilpine J Pharmacol Exp Ther 312 3 2005 1232 1240 (Pubitemid 40293785)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.312 , Issue.3 , pp. 1232-1240
    • Lee, B.1    Platt, D.M.2    Rowlett, J.K.3    Adewale, A.S.4    Spealman, R.D.5
  • 211
    • 77953615183 scopus 로고    scopus 로고
    • Metabotropic glutamate mGlu1 receptor stimulation and blockade: Therapeutic opportunities in psychiatric illness
    • A. Lesage, and T. Steckler Metabotropic glutamate mGlu1 receptor stimulation and blockade: therapeutic opportunities in psychiatric illness Eur J Pharmacol 639 1-3 2010 2 16
    • (2010) Eur J Pharmacol , vol.639 , Issue.13 , pp. 2-16
    • Lesage, A.1    Steckler, T.2
  • 212
    • 77955148819 scopus 로고    scopus 로고
    • Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats
    • X. Li, J. Li, E.L. Gardner, and Z.X. Xi Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats J Neurochem 114 5 2010 1368 1380
    • (2010) J Neurochem , vol.114 , Issue.5 , pp. 1368-1380
    • Li, X.1    Li, J.2    Gardner, E.L.3    Xi, Z.X.4
  • 213
    • 33748999574 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice
    • DOI 10.1124/jpet.106.103143
    • X. Li, A.B. Need, M. Baez, and J.M. Witkin Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice J Pharmacol Exp Ther 319 1 2006 254 259 (Pubitemid 44455130)
    • (2006) Journal of Pharmacology and Experimental Therapeutics , vol.319 , Issue.1 , pp. 254-259
    • Li, X.1    Need, A.B.2    Baez, M.3    Witkin, J.M.4
  • 214
    • 84872155535 scopus 로고    scopus 로고
    • Metabotropic glutamate 7 (mGlu7) receptor: A target for medication development for the treatment of cocaine dependence
    • X. Li, Z.X. Xi, and A. Markou Metabotropic glutamate 7 (mGlu7) receptor: a target for medication development for the treatment of cocaine dependence Neuropharmacology 66 2013 12 23
    • (2013) Neuropharmacology , vol.66 , pp. 12-23
    • Li, X.1    Xi, Z.X.2    Markou, A.3
  • 215
    • 34548685030 scopus 로고    scopus 로고
    • Metabotropic glutamate 2/3 receptor activation induced reward deficits but did not aggravate brain reward deficits associated with spontaneous nicotine withdrawal in rats
    • DOI 10.1016/j.bcp.2007.05.020, PII S0006295207003292
    • M.E. Liechti, and A. Markou Metabotropic glutamate 2/3 receptor activation induced reward deficits but did not aggravate brain reward deficits associated with spontaneous nicotine withdrawal in rats Biochem Pharmacol 74 8 2007 1299 1307 (Pubitemid 47417917)
    • (2007) Biochemical Pharmacology , vol.74 , Issue.8 , pp. 1299-1307
    • Liechti, M.E.1    Markou, A.2
  • 216
    • 33746106504 scopus 로고    scopus 로고
    • Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-Fos expression: Specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus
    • DOI 10.1016/j.neuropharm.2006.03.014, PII S0028390806000712
    • A.M. Linden, M. Baez, M. Bergeron, and D.D. Schoepp Effects of mGlu2 or mGlu3 receptor deletions on mGlu2/3 receptor agonist (LY354740)-induced brain c-fos expression: specific roles for mGlu2 in the amygdala and subcortical nuclei, and mGlu3 in the hippocampus Neuropharmacology 51 2 2006 213 228 (Pubitemid 44081793)
    • (2006) Neuropharmacology , vol.51 , Issue.2 , pp. 213-228
    • Linden, A.-M.1    Baez, M.2    Bergeron, M.3    Schoepp, D.D.4
  • 218
    • 17744396669 scopus 로고    scopus 로고
    • Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice
    • DOI 10.1007/s00213-004-2098-x
    • A.M. Linden, H. Shannon, M. Baez, J.L. Yu, A. Koester, and D.D. Schoepp Anxiolytic-like activity of the mGLU2/3 receptor agonist LY354740 in the elevated plus maze test is disrupted in metabotropic glutamate receptor 2 and 3 knock-out mice Psychopharmacology (Berl) 179 1 2005 284 291 (Pubitemid 40576716)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 284-291
    • Linden, A.-M.1    Shannon, H.2    Baez, M.3    Yu, J.L.4    Koester, A.5    Schoepp, D.D.6
  • 219
    • 84971012261 scopus 로고    scopus 로고
    • (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu(5): Discovery of a new tool compound with activity in the OSS mouse model of addiction
    • C.W. Lindsley, B.S. Bates, U.N. Menon, S.B. Jadhav, A.S. Kane, and C.K. Jones et al. (3-Cyano-5-fluorophenyl)biaryl negative allosteric modulators of mGlu(5): discovery of a new tool compound with activity in the OSS mouse model of addiction ACS Chem Neurosci 2 8 2011 471 482
    • (2011) ACS Chem Neurosci , vol.2 , Issue.8 , pp. 471-482
    • Lindsley, C.W.1    Bates, B.S.2    Menon, U.N.3    Jadhav, S.B.4    Kane, A.S.5    Jones, C.K.6
  • 221
    • 57349174038 scopus 로고    scopus 로고
    • ADX47273 [S-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5- yl]-piperidin-1-yl-methanone]: A novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities
    • F. Liu, S. Grauer, C. Kelley, R. Navarra, R. Graf, and G. Zhang et al. ADX47273 [S-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]- piperidin-1-yl-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities J Pharmacol Exp Ther 327 3 2008 827 839
    • (2008) J Pharmacol Exp Ther , vol.327 , Issue.3 , pp. 827-839
    • Liu, F.1    Grauer, S.2    Kelley, C.3    Navarra, R.4    Graf, R.5    Zhang, G.6
  • 222
    • 33748968301 scopus 로고    scopus 로고
    • Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: Potential insight into their anti-addictive properties
    • DOI 10.1016/j.drugalcdep.2006.04.003, PII S0376871606001414
    • K.D. Lominac, Z. Kapasova, R.A. Hannun, C. Patterson, L.D. Middaugh, and K.K. Szumlinski Behavioral and neurochemical interactions between group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties Drug Alcohol Depend 85 2 2006 142 156 (Pubitemid 44441668)
    • (2006) Drug and Alcohol Dependence , vol.85 , Issue.2 , pp. 142-156
    • Lominac, K.D.1    Kapasova, Z.2    Hannun, R.A.3    Patterson, C.4    Middaugh, L.D.5    Szumlinski, K.K.6
  • 223
    • 84855904904 scopus 로고    scopus 로고
    • Distinct neurochemical adaptations within the nucleus accumbens produced by a history of self-administered vs non-contingently administered intravenous methamphetamine
    • K.D. Lominac, A.D. Sacramento, K.K. Szumlinski, and T.E. Kippin Distinct neurochemical adaptations within the nucleus accumbens produced by a history of self-administered vs non-contingently administered intravenous methamphetamine Neuropsychopharmacology 37 3 2012 707 722
    • (2012) Neuropsychopharmacology , vol.37 , Issue.3 , pp. 707-722
    • Lominac, K.D.1    Sacramento, A.D.2    Szumlinski, K.K.3    Kippin, T.E.4
  • 224
    • 0030954048 scopus 로고    scopus 로고
    • Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP
    • Y.M. Lu, Z. Jia, C. Janus, J.T. Henderson, R. Gerlai, and J.M. Wojtowicz et al. Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP J Neurosci 17 13 1997 5196 5205 (Pubitemid 27263833)
    • (1997) Journal of Neuroscience , vol.17 , Issue.13 , pp. 5196-5205
    • Lu, Y.-M.1    Jia, Z.2    Janus, C.3    Henderson, J.T.4    Gerlai, R.5    Wojtowicz, J.M.6    Roder, J.C.7
  • 225
    • 45349107888 scopus 로고    scopus 로고
    • Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice
    • L. Lyon, J.N. Kew, C. Corti, P.J. Harrison, and P.W. Burnet Altered hippocampal expression of glutamate receptors and transporters in GRM2 and GRM3 knockout mice Synapse 62 11 2008 842 850
    • (2008) Synapse , vol.62 , Issue.11 , pp. 842-850
    • Lyon, L.1    Kew, J.N.2    Corti, C.3    Harrison, P.J.4    Burnet, P.W.5
  • 230
    • 0030221646 scopus 로고    scopus 로고
    • Human metabotropic glutamate receptor type 7: Molecular cloning and mRNA distribution in the CNS
    • DOI 10.1016/0169-328X(96)00110-6
    • A. Makoff, C. Pilling, K. Harrington, and P. Emson Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS Brain Res Mol Brain Res 40 1 1996 165 170 (Pubitemid 26241801)
    • (1996) Molecular Brain Research , vol.40 , Issue.1 , pp. 165-170
    • Makoff, A.1    Pilling, C.2    Harrington, K.3    Emson, P.4
  • 231
    • 0033586670 scopus 로고    scopus 로고
    • Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8
    • DOI 10.1016/S0169-328X(99)00050-9, PII S0169328X99000509
    • P. Malherbe, C. Kratzeisen, K. Lundstrom, J.G. Richards, R.L.M. Faull, and V. Mutel Cloning and functional expression of alternative spliced variants of the human metabotropic glutamate receptor 8 Mol Brain Res 67 2 1999 201 210 (Pubitemid 29193176)
    • (1999) Molecular Brain Research , vol.67 , Issue.2 , pp. 201-210
    • Malherbe, P.1    Kratzeisen, C.2    Lundstrom, K.3    Richards, J.G.4    Faull, R.L.M.5    Mutel, V.6
  • 232
    • 0034703530 scopus 로고    scopus 로고
    • Activation of group III metabotropic glutamate receptors inhibits basal and amphetamine-stimulated dopamine release in rat dorsal striatum: An in vivo microdialysis study
    • L. Mao, Y.S. Lau, and J.Q. Wang Activation of group III metabotropic glutamate receptors inhibits basal and amphetamine-stimulated dopamine release in rat dorsal striatum: an in vivo microdialysis study Eur J Pharmacol 404 3 2000 289 297
    • (2000) Eur J Pharmacol , vol.404 , Issue.3 , pp. 289-297
    • Mao, L.1    Lau, Y.S.2    Wang, J.Q.3
  • 234
    • 77953613109 scopus 로고    scopus 로고
    • Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition
    • G.J. Marek Metabotropic glutamate2/3 (mGlu2/3) receptors, schizophrenia and cognition Eur J Pharmacol 639 1-3 2010 81 90
    • (2010) Eur J Pharmacol , vol.639 , Issue.13 , pp. 81-90
    • Marek, G.J.1
  • 237
    • 0035783731 scopus 로고    scopus 로고
    • Presynaptic group I and II metabotropic glutamate receptors oppositely modulate striatal acetylcholine release
    • DOI 10.1046/j.0953-816X.2001.01750.x
    • M. Marti, F. Paganini, S. Stocchi, C. Bianchi, L. Beani, and M. Morari Presynaptic group I and II metabotropic glutamate receptors oppositely modulate striatal acetylcholine release Eur J Neurosci 14 7 2001 1181 1184 (Pubitemid 35463763)
    • (2001) European Journal of Neuroscience , vol.14 , Issue.7 , pp. 1181-1184
    • Marti, M.1    Paganini, F.2    Stocchi, S.3    Bianchi, C.4    Beani, L.5    Morari, M.6
  • 238
    • 66749130963 scopus 로고    scopus 로고
    • Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl) ethynyl]piperidine] on conditioned reinstatement and reinforcement: Comparison between cocaine and a conventional reinforcer
    • R. Martin-Fardon, M.A. Baptista, C.V. Dayas, and F. Weiss Dissociation of the effects of MTEP [3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine] on conditioned reinstatement and reinforcement: comparison between cocaine and a conventional reinforcer J Pharmacol Exp Ther 329 3 2009 1084 1090
    • (2009) J Pharmacol Exp Ther , vol.329 , Issue.3 , pp. 1084-1090
    • Martin-Fardon, R.1    Baptista, M.A.2    Dayas, C.V.3    Weiss, F.4
  • 239
    • 84860243867 scopus 로고    scopus 로고
    • (-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6-dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking
    • R. Martin-Fardon, and F. Weiss (-)-2-oxa-4-aminobicylco[3.1.0]hexane-4,6- dicarboxylic acid (LY379268) and 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] piperidine (MTEP) similarly attenuate stress-induced reinstatement of cocaine seeking Addict Biol 17 3 2012 557 564
    • (2012) Addict Biol , vol.17 , Issue.3 , pp. 557-564
    • Martin-Fardon, R.1    Weiss, F.2
  • 240
    • 0037363728 scopus 로고    scopus 로고
    • Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP
    • DOI 10.1038/sj.bjp.0705159
    • J.M. Mathiesen, N. Svendsen, H. Brauner-Osborne, C. Thomsen, and M.T. Ramirez Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP Br J Pharmacol 138 6 2003 1026 1030 (Pubitemid 36459824)
    • (2003) British Journal of Pharmacology , vol.138 , Issue.6 , pp. 1026-1030
    • Mathiesen, J.M.1    Svendsen, N.2    Brauner-Osborne, H.3    Thomsen, C.4    Ramirez, M.T.5
  • 241
    • 49949115549 scopus 로고    scopus 로고
    • Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats
    • F. Matrisciano, A. Caruso, R. Orlando, M. Marchiafava, V. Bruno, and G. Battaglia et al. Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats Neuropharmacology 55 4 2008 525 531
    • (2008) Neuropharmacology , vol.55 , Issue.4 , pp. 525-531
    • Matrisciano, F.1    Caruso, A.2    Orlando, R.3    Marchiafava, M.4    Bruno, V.5    Battaglia, G.6
  • 242
    • 34547397923 scopus 로고    scopus 로고
    • Group-II metabotropic glutamate receptor ligands as adjunctive drugs in the treatment of depression: A new strategy to shorten the latency of antidepressant medication?
    • DOI 10.1038/sj.mp.4002005, PII 4002005
    • F. Matrisciano, I. Panaccione, M. Zusso, P. Giusti, R. Tatarelli, and L. Iacovelli et al. Group-II metabotropic glutamate receptor ligands as adjunctive drugs in the treatment of depression: a new strategy to shorten the latency of antidepressant medication? Mol Psychiatry 12 8 2007 704 706 (Pubitemid 47172692)
    • (2007) Molecular Psychiatry , vol.12 , Issue.8 , pp. 704-706
    • Matrisciano, F.1    Panaccione, I.2    Zusso, M.3    Giusti, P.4    Tatarelli, R.5    Iacovelli, L.6    Mathe, A.A.7    Gruber, S.H.M.8    Nicoletti, F.9    Girardi, P.10
  • 243
    • 0036070326 scopus 로고    scopus 로고
    • Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus
    • DOI 10.1016/S0028-3908(02)00057-6, PII S0028390802000576
    • F. Matrisciano, M. Storto, R.T. Ngomba, I. Cappuccio, A. Caricasole, and S. Scaccianoce et al. Imipramine treatment up-regulates the expression and function of mGlu2/3 metabotropic glutamate receptors in the rat hippocampus Neuropharmacology 42 8 2002 1008 1015 (Pubitemid 34786554)
    • (2002) Neuropharmacology , vol.42 , Issue.8 , pp. 1008-1015
    • Matrisciano, F.1    Storto, M.2    Ngomba, R.T.3    Cappuccio, I.4    Caricasole, A.5    Scaccianoce, S.6    Riozzi, B.7    Melchiorri, D.8    Nicoletti, F.9
  • 244
    • 0035206385 scopus 로고    scopus 로고
    • Molecular mechanisms of cystine transport
    • DOI 10.1042/0300-5127:0290717
    • G.J. McBean, and J. Flynn Molecular mechanisms of cystine transport Biochem Soc Trans 29 Pt 6 2001 717 722 (Pubitemid 33131768)
    • (2001) Biochemical Society Transactions , vol.29 , Issue.6 , pp. 717-722
    • McBean, G.J.1    Flynn, J.2
  • 245
    • 0037693859 scopus 로고    scopus 로고
    • Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior
    • K. McFarland, C.C. Lapish, and P.W. Kalivas Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior J Neurosci 23 8 2003 3531 3537 (Pubitemid 36531996)
    • (2003) Journal of Neuroscience , vol.23 , Issue.8 , pp. 3531-3537
    • McFarland, K.1    Lapish, C.C.2    Kalivas, P.W.3
  • 246
    • 0037337238 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse
    • DOI 10.1002/syn.10166
    • A.J. McGeehan, and M.F. Olive The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse Synapse 47 3 2003 240 242 (Pubitemid 36056837)
    • (2003) Synapse , vol.47 , Issue.3 , pp. 240-242
    • McGeehan, A.J.1    Olive, M.F.2
  • 247
    • 27744477334 scopus 로고    scopus 로고
    • Effects of a metabollic, mGlu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats
    • DOI 10.1093/alcalc/agh200
    • B.A. McMillen, M.S. Crawford, C.M. Kulers, and H.L. Williams Effects of a metabotropic, mglu5, glutamate receptor antagonist on ethanol consumption by genetic drinking rats Alcohol Alcohol 40 6 2005 494 497 (Pubitemid 41599998)
    • (2005) Alcohol and Alcoholism , vol.40 , Issue.6 , pp. 494-497
    • McMillen, B.A.1    Crawford, M.S.2    Kulers, C.M.3    Williams, H.L.4
  • 248
    • 84866696413 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors inhibit microglial glutamate release
    • 10.1042/AN20120044 (art:e00094)
    • S.M. McMullan, B. Phanavanh, G.G. Li, and S.W. Barger Metabotropic glutamate receptors inhibit microglial glutamate release ASN Neuro 4 5 2012 10.1042/AN20120044 (art:e00094)
    • (2012) ASN Neuro , vol.4 , Issue.5
    • McMullan, S.M.1    Phanavanh, B.2    Li, G.G.3    Barger, S.W.4
  • 249
    • 38349120971 scopus 로고    scopus 로고
    • Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: A time course microdialysis study
    • M. Miguens, N.D. Olmo, A. Higuera-Matas, I. Torres, C. Garcia-Lecumberri, and E. Ambrosio Glutamate and aspartate levels in the nucleus accumbens during cocaine self-administration and extinction: a time course microdialysis study Psychopharmacology (Berl) 196 2 2008 303 313
    • (2008) Psychopharmacology (Berl) , vol.196 , Issue.2 , pp. 303-313
    • Miguens, M.1    Olmo, N.D.2    Higuera-Matas, A.3    Torres, I.4    Garcia-Lecumberri, C.5    Ambrosio, E.6
  • 250
    • 0030806935 scopus 로고    scopus 로고
    • Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro
    • DOI 10.1074/jbc.272.32.20291
    • R. Minakami, N. Jinnai, and H. Sugiyama Phosphorylation and calmodulin binding of the metabotropic glutamate receptor subtype 5 (mGluR5) are antagonistic in vitro J Biol Chem 272 32 1997 20291 20298 (Pubitemid 27340143)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.32 , pp. 20291-20298
    • Minakami, R.1    Jinnai, N.2    Sugiyama, H.3
  • 251
    • 0029880088 scopus 로고    scopus 로고
    • Differences in agonist and antagonist activities for two indices of metabotropic glutamate receptor-stimulated phosphoinositide turnover
    • R. Mistry, and R.A.J. Challiss Differences in agonist and antagonist activities for two indices of metabotropic glutamate receptor-stimulated phosphoinositide turnover Br J Pharmacol 117 8 1996 1735 1743 (Pubitemid 26121619)
    • (1996) British Journal of Pharmacology , vol.117 , Issue.8 , pp. 1735-1743
    • Mistry, R.1    Challiss, R.A.J.2
  • 252
    • 33745675486 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: Implications for stress-related psychiatric disorders
    • DOI 10.1038/sj.npp.1300926, PII 1300926
    • K. Mitsukawa, C. Mombereau, E. Lotscher, D.P. Uzunov, H.v.d. Putten, and P.J. Flor et al. Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders Neuropsychopharmacology 31 6 2006 1112 1122 (Pubitemid 43971829)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.6 , pp. 1112-1122
    • Mitsukawa, K.1    Mombereau, C.2    Lotscher, E.3    Uzunov, D.P.4    Van Der Putten, H.5    Flor, P.J.6    Cryan, J.F.7
  • 254
    • 26644459703 scopus 로고    scopus 로고
    • Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence
    • DOI 10.1111/j.1460-9568.2005.04325.x
    • M. Miyatake, M. Narita, M. Shibasaki, A. Nakamura, and T. Suzuki Glutamatergic neurotransmission and protein kinase C play a role in neuron-glia communication during the development of methamphetamine-induced psychological dependence Eur J Neurosci 22 6 2005 1476 1488 (Pubitemid 41442419)
    • (2005) European Journal of Neuroscience , vol.22 , Issue.6 , pp. 1476-1488
    • Miyatake, M.1    Narita, M.2    Shibasaki, M.3    Nakamura, A.4    Suzuki, T.5
  • 255
    • 0035054108 scopus 로고    scopus 로고
    • Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice
    • DOI 10.1016/S0028-3908(01)00002-8, PII S0028390801000028
    • R.X. Moldrich, P.M. Beart, D.E. Jane, A.G. Chapman, and B.S. Meldrum Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice Neuropharmacology 40 5 2001 732 735 (Pubitemid 32323997)
    • (2001) Neuropharmacology , vol.40 , Issue.5 , pp. 732-735
    • Moldrich, R.X.1    Beart, P.M.2    Jane, D.E.3    Chapman, A.G.4    Meldrum, B.S.5
  • 256
    • 0034964561 scopus 로고    scopus 로고
    • Anti-epileptic activity of group II metabotropic glutamate receptor agonists (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (-)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795)
    • DOI 10.1016/S0028-3908(01)00044-2, PII S0028390801000442
    • R.X. Moldrich, M. Jeffrey, A. Talebi, P.M. Beart, A.G. Chapman, and B.S. Meldrum Anti-epileptic activity of group II metabotropic glutamate receptor agonists (-)-2-oxa-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY379268) and (-)-2-thia-4-aminobicyclo[3.1.0]hexane-4,6-dicarboxylate (LY389795) Neuropharmacology 41 1 2001 8 18 (Pubitemid 32607640)
    • (2001) Neuropharmacology , vol.41 , Issue.1 , pp. 8-18
    • Moldrich, R.X.1    Jeffrey, M.2    Talebi, A.3    Beart, P.M.4    Chapman, A.G.5    Meldrum, B.S.6
  • 259
    • 21844443565 scopus 로고    scopus 로고
    • Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking
    • DOI 10.1523/JNEUROSCI.1007-05.2005
    • M.M. Moran, K. McFarland, R.I. Melendez, P.W. Kalivas, and J.K. Seamans Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking J Neurosci 25 27 2005 6389 6393 (Pubitemid 40962534)
    • (2005) Journal of Neuroscience , vol.25 , Issue.27 , pp. 6389-6393
    • Moran, M.M.1    McFarland, K.2    Melendez, R.I.3    Kalivas, P.W.4    Seamans, J.K.5
  • 263
    • 0034649605 scopus 로고    scopus 로고
    • Synthesis, SARs, and pharmacological characterization of 2-Amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists
    • DOI 10.1021/jm000346k
    • A. Nakazato, T. Kumagai, K. Sakagami, R. Yoshikawa, Y. Suzuki, and S. Chaki et al. Synthesis, SARs, and pharmacological characterization of 2-amino-3 or 6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent, selective, and orally active group II metabotropic glutamate receptor agonists J Med Chem 43 25 2000 4893 4909 (Pubitemid 32002702)
    • (2000) Journal of Medicinal Chemistry , vol.43 , Issue.25 , pp. 4893-4909
    • Nakazato, A.1    Kumagai, T.2    Sakagami, K.3    Yoshikawa, R.4    Suzuki, Y.5    Chaki, S.6    Ito, H.7    Taguchi, T.8    Nakanishi, S.9    Okuyama, S.10
  • 264
    • 38149108182 scopus 로고    scopus 로고
    • Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures
    • R.T. Ngomba, F. Ferraguti, A. Badura, R. Citraro, I. Santolini, and G. Battaglia et al. Positive allosteric modulation of metabotropic glutamate 4 (mGlu4) receptors enhances spontaneous and evoked absence seizures Neuropharmacology 54 2 2008 344 354
    • (2008) Neuropharmacology , vol.54 , Issue.2 , pp. 344-354
    • Ngomba, R.T.1    Ferraguti, F.2    Badura, A.3    Citraro, R.4    Santolini, I.5    Battaglia, G.6
  • 265
    • 33646569145 scopus 로고    scopus 로고
    • MGluR2 acts through inhibitory galpha subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses
    • R.E. Nicholls, X.L. Zhang, C.P. Bailey, B.R. Conklin, E.R. Kandel, and P.K. Stanton mGluR2 acts through inhibitory galpha subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses Proc Natl Acad Sci U S A 103 16 2006 6380 6385
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.16 , pp. 6380-6385
    • Nicholls, R.E.1    Zhang, X.L.2    Bailey, C.P.3    Conklin, B.R.4    Kandel, E.R.5    Stanton, P.K.6
  • 266
    • 54349110319 scopus 로고    scopus 로고
    • Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4
    • C.M. Niswender, K.A. Johnson, C.D. Weaver, C.K. Jones, Z. Xiang, and Q. Luo et al. Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4 Mol Pharmacol 74 5 2008 1345 1358
    • (2008) Mol Pharmacol , vol.74 , Issue.5 , pp. 1345-1358
    • Niswender, C.M.1    Johnson, K.A.2    Weaver, C.D.3    Jones, C.K.4    Xiang, Z.5    Luo, Q.6
  • 267
    • 84875416160 scopus 로고    scopus 로고
    • A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling
    • M.J. Noetzel, K.J. Gregory, P.N. Vinson, J.T. Manka, S.R. Stauffer, and C.W. Lindsley et al. A novel metabotropic glutamate receptor 5 positive allosteric modulator acts at a unique site and confers stimulus bias to mGlu5 signaling Mol Pharmacol 83 4 2013 835 847
    • (2013) Mol Pharmacol , vol.83 , Issue.4 , pp. 835-847
    • Noetzel, M.J.1    Gregory, K.J.2    Vinson, P.N.3    Manka, J.T.4    Stauffer, S.R.5    Lindsley, C.W.6
  • 268
    • 0028218968 scopus 로고
    • Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells
    • DOI 10.1016/0092-8674(94)90151-1
    • A. Nomura, R. Shigemoto, Y. Nakamura, N. Okamoto, N. Mizuno, and S. Nakanishi Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells Cell 77 3 1994 361 369 (Pubitemid 24145197)
    • (1994) Cell , vol.77 , Issue.3 , pp. 361-369
    • Nomura, A.1    Shigemoto, R.2    Nakamura, Y.3    Okamoto, N.4    Mizuno, N.5    Nakanishi, S.6
  • 270
    • 0029120580 scopus 로고
    • Distributions of the mRNAs for l-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain
    • H. Ohishi, C. Akazawa, R. Shigemoto, S. Nakanishi, and N. Mizuno Distributions of the mRNAs for l-2-amino-4-phosphonobutyrate-sensitive metabotropic glutamate receptors, mGluR4 and mGluR7, in the rat brain J Comp Neurol 360 4 1995 555 570
    • (1995) J Comp Neurol , vol.360 , Issue.4 , pp. 555-570
    • Ohishi, H.1    Akazawa, C.2    Shigemoto, R.3    Nakanishi, S.4    Mizuno, N.5
  • 271
    • 0031951227 scopus 로고    scopus 로고
    • Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: An immunohistochemical study with a monoclonal antibody
    • DOI 10.1016/S0168-0102(97)00120-X, PII S016801029700120X
    • H. Ohishi, A. Neki, and N. Mizuno Distribution of a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat and mouse: an immunohistochemical study with a monoclonal antibody Neurosci Res 30 1 1998 65 82 (Pubitemid 28119150)
    • (1998) Neuroscience Research , vol.30 , Issue.1 , pp. 65-82
    • Ohishi, H.1    Neki, A.2    Mizuno, N.3
  • 272
    • 0029566973 scopus 로고
    • Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: An immunohistochemical study in the rat
    • DOI 10.1016/0304-3940(95)12207-9
    • H. Ohishi, S. Nomura, Y.Q. Ding, R. Shigemoto, E. Wada, and A. Kinoshita et al. Presynaptic localization of a metabotropic glutamate receptor, mGluR7, in the primary afferent neurons: an immunohistochemical study in the rat Neurosci Lett 202 1-2 1995 85 88 (Pubitemid 26011563)
    • (1995) Neuroscience Letters , vol.202 , Issue.1-2 , pp. 85-88
    • Ohishi, H.1    Nomura, S.2    Ding, Y.-Q.3    Shigemoto, R.4    Wada, E.5    Kinoshita, A.6    Li, J.-L.7    Neki, A.8    Nakanishi, S.9    Mizuno, N.10
  • 273
    • 0027190384 scopus 로고
    • Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat
    • DOI 10.1016/0306-4522(93)90485-X
    • H. Ohishi, R. Shigemoto, S. Nakanishi, and N. Mizuno Distribution of the messenger RNA for a metabotropic glutamate receptor, mGluR2, in the central nervous system of the rat Neuroscience 53 4 1993 1009 1018 (Pubitemid 23126097)
    • (1993) Neuroscience , vol.53 , Issue.4 , pp. 1009-1018
    • Ohishi, H.1    Shigemoto, R.2    Nakanishi, S.3    Mizuno, N.4
  • 274
    • 70349782435 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor ligands as potential therapeutics for addiction
    • M.F. Olive Metabotropic glutamate receptor ligands as potential therapeutics for addiction Curr Drug Abuse Rev 2 1 2009 83 98
    • (2009) Curr Drug Abuse Rev , vol.2 , Issue.1 , pp. 83-98
    • Olive, M.F.1
  • 275
    • 13444291828 scopus 로고    scopus 로고
    • The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase Cε-dependent mechanism
    • DOI 10.1124/mol.104.003319
    • M.F. Olive, A.J. McGeehan, J.R. Kinder, T. McMahon, C.W. Hodge, and P.H. Janak et al. The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism Mol Pharmacol 67 2 2005 349 355 (Pubitemid 40216726)
    • (2005) Molecular Pharmacology , vol.67 , Issue.2 , pp. 349-355
    • Olive, M.F.1    Mcgeehan, A.J.2    Kinder, J.R.3    McMahon, T.4    Hodge, C.W.5    Janak, P.H.6    Messing, R.O.7
  • 276
    • 53549123027 scopus 로고    scopus 로고
    • A role for mGluR5 receptors in intravenous methamphetamine self-administration
    • M.P. Osborne, and M.F. Olive A role for mGluR5 receptors in intravenous methamphetamine self-administration Ann N Y Acad Sci 1139 2008 206 211
    • (2008) Ann N y Acad Sci , vol.1139 , pp. 206-211
    • Osborne, M.P.1    Olive, M.F.2
  • 277
    • 0033571938 scopus 로고    scopus 로고
    • Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
    • S. Otani, N. Auclair, J.M. Desce, M.P. Roisin, and F. Crepel Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases J Neurosci 19 22 1999 9788 9802 (Pubitemid 30226652)
    • (1999) Journal of Neuroscience , vol.19 , Issue.22 , pp. 9788-9802
    • Otani, S.1    Auclair, N.2    Desce, J.-M.3    Roisin, M.-P.4    Crepel, F.5
  • 278
    • 0031466662 scopus 로고    scopus 로고
    • Organization of glutamate receptors at the synapse
    • DOI 10.1111/j.1460-9568.1997.tb01640.x
    • O.P. Ottersen, and A.S. Landsend Organization of glutamate receptors at the synapse Eur J Neurosci 9 11 1997 2219 2224 (Pubitemid 28005975)
    • (1997) European Journal of Neuroscience , vol.9 , Issue.11 , pp. 2219-2224
    • Ottersen, O.P.1    Landsend, A.S.2
  • 279
    • 49949087048 scopus 로고    scopus 로고
    • Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors
    • E. Palazzo, Y. Fu, G. Ji, S. Maione, and V. Neugebauer Group III mGluR7 and mGluR8 in the amygdala differentially modulate nocifensive and affective pain behaviors Neuropharmacology 55 4 2008 537 545
    • (2008) Neuropharmacology , vol.55 , Issue.4 , pp. 537-545
    • Palazzo, E.1    Fu, Y.2    Ji, G.3    Maione, S.4    Neugebauer, V.5
  • 280
    • 47249104677 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine
    • DOI 10.1038/sj.npp.1301623, PII 1301623
    • M.I. Palmatier, X. Liu, E.C. Donny, A.R. Caggiula, and A.F. Sved Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine Neuropsychopharmacology 33 9 2008 2139 2147 (Pubitemid 351992092)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.9 , pp. 2139-2147
    • Palmatier, M.I.1    Liu, X.2    Donny, E.C.3    Caggiula, A.R.4    Sved, A.F.5
  • 281
    • 14244249956 scopus 로고    scopus 로고
    • Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms
    • A. Palucha, P. Branski, and A. Pilc Selective mGlu5 receptor antagonist MTEP attenuates naloxone-induced morphine withdrawal symptoms Pol J Pharmacol 56 6 2004 863 866 (Pubitemid 40287491)
    • (2004) Polish Journal of Pharmacology , vol.56 , Issue.6 , pp. 863-866
    • Palucha, A.1    Branski, P.2    Pilc, A.3
  • 282
    • 34848860791 scopus 로고    scopus 로고
    • Activation of the mGlu7 receptor elicits antidepressant-like effects in mice
    • DOI 10.1007/s00213-007-0856-2
    • A. Palucha, K. Klak, P. Branski, H.v.d. Putten, P.J. Flor, and A. Pilc Activation of the mGlu7 receptor elicits antidepressant-like effects in mice Psychopharmacology (Berl) 194 4 2007 555 562 (Pubitemid 47492987)
    • (2007) Psychopharmacology , vol.194 , Issue.4 , pp. 555-562
    • Palucha, A.1    Klak, K.2    Branski, P.3    Van Der Putten, H.4    Flor, P.J.5    Pilc, A.6
  • 283
    • 34347241277 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs
    • DOI 10.1016/j.pharmthera.2007.04.007, PII S0163725807000848
    • A. Palucha, and A. Pilc Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs Pharmacol Ther 115 1 2007 116 147 (Pubitemid 46992810)
    • (2007) Pharmacology and Therapeutics , vol.115 , Issue.1 , pp. 116-147
    • Palucha, A.1    Pilc, A.2
  • 285
    • 77956257563 scopus 로고    scopus 로고
    • The antidepressant-like action of metabotropic glutamate 7 receptor agonist N, N′-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent
    • A. Palucha-Poniewiera, P. Branski, T. Lenda, and A. Pilc The antidepressant-like action of metabotropic glutamate 7 receptor agonist N, N′-bis(diphenylmethyl)-1,2-ethanediamine (AMN082) is serotonin-dependent J Pharmacol Exp Ther 334 3 2010 1066 1074
    • (2010) J Pharmacol Exp Ther , vol.334 , Issue.3 , pp. 1066-1074
    • Palucha-Poniewiera, A.1    Branski, P.2    Lenda, T.3    Pilc, A.4
  • 286
    • 17744383991 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats
    • DOI 10.1007/s00213-004-2070-9
    • N.E. Paterson, and A. Markou The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats Psychopharmacology (Berl) 179 1 2005 255 261 (Pubitemid 40576713)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 255-261
    • Paterson, N.E.1    Markou, A.2
  • 287
    • 0038240644 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice
    • N.E. Paterson, S. Semenova, F. Gasparini, and A. Markou The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice Psychopharmacology (Berl) 167 3 2003 257 264 (Pubitemid 36712972)
    • (2003) Psychopharmacology , vol.167 , Issue.3 , pp. 257-264
    • Paterson, N.E.1    Semenova, S.2    Gasparini, F.3    Markou, A.4
  • 289
  • 291
    • 0029126126 scopus 로고
    • 1-Aminoindan-1,5-dicarboxylic acid: A novel antagonist at phospholipase C-linked metabotropic glutamate receptors
    • R. Pellicciari, R. Luneia, G. Costantino, M. Marinozzi, B. Natalini, and P. Jakobsen et al. 1-Aminoindan-1,5-dicarboxylic acid: a novel antagonist at phospholipase C-linked metabotropic glutamate receptors J Med Chem 38 19 1995 3717 3719
    • (1995) J Med Chem , vol.38 , Issue.19 , pp. 3717-3719
    • Pellicciari, R.1    Luneia, R.2    Costantino, G.3    Marinozzi, M.4    Natalini, B.5    Jakobsen, P.6
  • 292
    • 60149105533 scopus 로고    scopus 로고
    • Computational model of extracellular glutamate in the nucleus accumbens incorporates neuroadaptations by chronic cocaine
    • S. Pendyam, A. Mohan, P.W. Kalivas, and S.S. Nair Computational model of extracellular glutamate in the nucleus accumbens incorporates neuroadaptations by chronic cocaine Neuroscience 158 4 2009 1266 1276
    • (2009) Neuroscience , vol.158 , Issue.4 , pp. 1266-1276
    • Pendyam, S.1    Mohan, A.2    Kalivas, P.W.3    Nair, S.S.4
  • 293
    • 33646565030 scopus 로고    scopus 로고
    • The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats
    • DOI 10.1007/s00213-006-0372-9
    • J. Peters, and P.W. Kalivas The group II metabotropic glutamate receptor agonist, LY379268, inhibits both cocaine- and food-seeking behavior in rats Psychopharmacology (Berl) 186 2 2006 143 149 (Pubitemid 43727330)
    • (2006) Psychopharmacology , vol.186 , Issue.2 , pp. 143-149
    • Peters, J.1    Kalivas, P.W.2
  • 295
    • 38949115944 scopus 로고    scopus 로고
    • Mood disorders: Regulation by metabotropic glutamate receptors
    • A. Pilc, S. Chaki, G. Nowak, and J.M. Witkin Mood disorders: regulation by metabotropic glutamate receptors Biochem Pharmacol 75 5 2008 997 1006
    • (2008) Biochem Pharmacol , vol.75 , Issue.5 , pp. 997-1006
    • Pilc, A.1    Chaki, S.2    Nowak, G.3    Witkin, J.M.4
  • 297
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • J.P. Pin, and R. Duvoisin The metabotropic glutamate receptors: structure and functions Neuropharmacology 34 1 1995 1 26
    • (1995) Neuropharmacology , vol.34 , Issue.1 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 300
    • 0030898586 scopus 로고    scopus 로고
    • Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones
    • DOI 10.1038/sj.bjp.0700999
    • A. Pisani, P. Calabresi, D. Centonze, and G. Bernardi Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones Br J Pharmacol 120 6 1997 1007 1014 (Pubitemid 27122637)
    • (1997) British Journal of Pharmacology , vol.120 , Issue.6 , pp. 1007-1014
    • Pisani, A.1    Calabresi, P.2    Centonze, D.3    Bernardi, G.4
  • 301
    • 51249102144 scopus 로고    scopus 로고
    • Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: Comparison with dizocilpine
    • D.M. Platt, J.K. Rowlett, and R.D. Spealman Attenuation of cocaine self-administration in squirrel monkeys following repeated administration of the mGluR5 antagonist MPEP: comparison with dizocilpine Psychopharmacology (Berl) 200 2 2008 167 176
    • (2008) Psychopharmacology (Berl) , vol.200 , Issue.2 , pp. 167-176
    • Platt, D.M.1    Rowlett, J.K.2    Spealman, R.D.3
  • 302
    • 0036951025 scopus 로고    scopus 로고
    • Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist
    • DOI 10.1016/S0028-3908(02)00309-X
    • P. Popik, and M. Wrobel Morphine conditioned reward is inhibited by MPEP, the mGluR5 antagonist Neuropharmacology 43 8 2002 1210 1217 (Pubitemid 36084432)
    • (2002) Neuropharmacology , vol.43 , Issue.8 , pp. 1210-1217
    • Popik, P.1    Wrobel, M.2
  • 304
    • 84866331745 scopus 로고    scopus 로고
    • A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease
    • E.L. Poul, C. Bolea, F. Girard, S. Poli, D. Charvin, and B. Campo et al. A potent and selective metabotropic glutamate receptor 4 positive allosteric modulator improves movement in rodent models of Parkinson's disease J Pharmacol Exp Ther 343 1 2012 167 177
    • (2012) J Pharmacol Exp Ther , vol.343 , Issue.1 , pp. 167-177
    • Poul, E.L.1    Bolea, C.2    Girard, F.3    Poli, S.4    Charvin, D.5    Campo, B.6
  • 305
    • 0028331717 scopus 로고
    • Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures
    • L. Prezeau, J. Carrette, B. Helpap, K. Curry, J.P. Pin, and J. Bockaert Pharmacological characterization of metabotropic glutamate receptors in several types of brain cells in primary cultures Mol Pharmacol 45 4 1994 570 577 (Pubitemid 24139182)
    • (1994) Molecular Pharmacology , vol.45 , Issue.4 , pp. 570-577
    • Prezeau, L.1    Carrette, J.2    Helpap, B.3    Curry, K.4    Pin, J.P.5    Bockaert, J.6
  • 306
    • 84866482721 scopus 로고    scopus 로고
    • Conserved cellular distribution of the glutamate receptors GluA2/3, mGlu1a and mGlu2/3 in isolated cultures of rat cerebellum
    • A. Ramos-Uriarte, I. Elezgarai, P. Grandes, and S.M. Gomez-Urquijo Conserved cellular distribution of the glutamate receptors GluA2/3, mGlu1a and mGlu2/3 in isolated cultures of rat cerebellum J Chem Neuroanat 45 1-2 2012 26 35
    • (2012) J Chem Neuroanat , vol.45 , Issue.12 , pp. 26-35
    • Ramos-Uriarte, A.1    Elezgarai, I.2    Grandes, P.3    Gomez-Urquijo, S.M.4
  • 307
    • 13444263521 scopus 로고    scopus 로고
    • The mGlu5 receptor antagonists MPEP and MTEP attenuate behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons in rats
    • DOI 10.1016/j.neuropharm.2004.09.010
    • K. Rasmussen, H. Martin, J.E. Berger, and M.A. Seager The mGlu5 receptor antagonists MPEP and MTEP attenuate behavioral signs of morphine withdrawal and morphine-withdrawal-induced activation of locus coeruleus neurons in rats Neuropharmacology 48 2 2005 173 180 (Pubitemid 40208253)
    • (2005) Neuropharmacology , vol.48 , Issue.2 , pp. 173-180
    • Rasmussen, K.1    Martin, H.2    Berger, J.E.3    Seager, M.A.4
  • 308
    • 80053582149 scopus 로고    scopus 로고
    • Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdala
    • W. Ren, E. Palazzo, S. Maione, and V. Neugebauer Differential effects of mGluR7 and mGluR8 activation on pain-related synaptic activity in the amygdala Neuropharmacology 61 8 2011 1334 1344
    • (2011) Neuropharmacology , vol.61 , Issue.8 , pp. 1334-1344
    • Ren, W.1    Palazzo, E.2    Maione, S.3    Neugebauer, V.4
  • 310
    • 33751099822 scopus 로고    scopus 로고
    • Intrinsic ON responses of the retinal OFF pathway are suppressed by the ON pathway
    • DOI 10.1523/JNEUROSCI.1718-06.2006
    • R.C. Renteria, N. Tian, J. Cang, S. Nakanishi, M.P. Stryker, and D.R. Copenhagen Intrinsic ON responses of the retinal OFF pathway are suppressed by the ON pathway J Neurosci 26 46 2006 11857 11869 (Pubitemid 44772096)
    • (2006) Journal of Neuroscience , vol.26 , Issue.46 , pp. 11857-11869
    • Renteria, R.C.1    Tian, N.2    Cang, J.3    Nakanishi, S.4    Stryker, M.P.5    Copenhagen, D.R.6
  • 312
    • 80051716135 scopus 로고    scopus 로고
    • Recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as CNS therapeutics
    • A.J. Robichaud, D.W. Engers, C.W. Lindsley, and C.R. Hopkins Recent progress on the identification of metabotropic glutamate 4 receptor ligands and their potential utility as CNS therapeutics ACS Chem Neurosci 2 8 2011 433 449
    • (2011) ACS Chem Neurosci , vol.2 , Issue.8 , pp. 433-449
    • Robichaud, A.J.1    Engers, D.W.2    Lindsley, C.W.3    Hopkins, C.R.4
  • 313
    • 0037096244 scopus 로고    scopus 로고
    • The Group I Metabotropic Glutamate Receptor mGluR5 Is Required for Fear Memory Formation and Long-Term Potentiation in the Lateral Amygdala
    • S.M. Rodrigues, E.P. Bauer, C.R. Farb, G.E. Schafe, and J.E. LeDoux The group I metabotropic glutamate receptor mGluR5 is required for fear memory formation and long-term potentiation in the lateral amygdala J Neurosci 22 12 2002 5219 5229 (Pubitemid 37465635)
    • (2002) Journal of Neuroscience , vol.22 , Issue.12 , pp. 5219-5229
    • Rodrigues, S.M.1    Bauer, E.P.2    Farb, C.R.3    Schafe, G.E.4    LeDoux, J.E.5
  • 314
    • 78649919580 scopus 로고    scopus 로고
    • Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity
    • A.L. Rodriguez, M.D. Grier, C.K. Jones, E.J. Herman, A.S. Kane, and R.L. Smith et al. Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity Mol Pharmacol 78 6 2010 1105 1123
    • (2010) Mol Pharmacol , vol.78 , Issue.6 , pp. 1105-1123
    • Rodriguez, A.L.1    Grier, M.D.2    Jones, C.K.3    Herman, E.J.4    Kane, A.S.5    Smith, R.L.6
  • 315
    • 84872163267 scopus 로고    scopus 로고
    • Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG)
    • C. Romei, M. Raiteri, and L. Raiteri Glycine release is regulated by metabotropic glutamate receptors sensitive to mGluR2/3 ligands and activated by N-acetylaspartylglutamate (NAAG) Neuropharmacology 66 2013 311 316
    • (2013) Neuropharmacology , vol.66 , pp. 311-316
    • Romei, C.1    Raiteri, M.2    Raiteri, L.3
  • 316
    • 38349029199 scopus 로고    scopus 로고
    • Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation
    • J.A. Ronesi, and K.M. Huber Homer interactions are necessary for metabotropic glutamate receptor-induced long-term depression and translational activation J Neurosci 28 2 2008 543 547
    • (2008) J Neurosci , vol.28 , Issue.2 , pp. 543-547
    • Ronesi, J.A.1    Huber, K.M.2
  • 317
    • 27744446102 scopus 로고    scopus 로고
    • Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands
    • DOI 10.1007/s00213-005-0169-2
    • L.M. Rorick-Kehn, J.C. Hart, and D.L. McKinzie Pharmacological characterization of stress-induced hyperthermia in DBA/2 mice using metabotropic and ionotropic glutamate receptor ligands Psychopharmacology (Berl) 183 2 2005 226 240 (Pubitemid 41609275)
    • (2005) Psychopharmacology , vol.183 , Issue.2 , pp. 226-240
    • Rorick-Kehn, L.M.1    Hart, J.C.2    McKinzie, D.L.3
  • 319
    • 4844229359 scopus 로고    scopus 로고
    • Molecular basis for the differential agonist affinities of group III metabotropic glutamate receptors
    • DOI 10.1124/mol.104.002956
    • E. Rosemond, M. Wang, Y. Yao, L. Storjohann, T. Stormann, and E.C. Johnson et al. Molecular basis for the differential agonist affinities of group III metabotropic glutamate receptors Mol Pharmacol 66 4 2004 834 842 (Pubitemid 39319455)
    • (2004) Molecular Pharmacology , vol.66 , Issue.4 , pp. 834-842
    • Rosemond, E.1    Wang, M.2    Yao, Y.3    Storjohann, L.4    Stormann, T.5    Johnson, E.C.6    Hampson, D.R.7
  • 320
    • 78649948724 scopus 로고    scopus 로고
    • The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats
    • K. Rutten, E.L. Van Der Kam, J. De Vry, W. Bruckmann, and T.M. Tzschentke The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats Addict Biol 16 1 2011 108 115
    • (2011) Addict Biol , vol.16 , Issue.1 , pp. 108-115
    • Rutten, K.1    Van Der Kam, E.L.2    De Vry, J.3    Bruckmann, W.4    Tzschentke, T.M.5
  • 321
    • 50349086591 scopus 로고    scopus 로고
    • Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082
    • M.C. Salling, S. Faccidomo, and C.W. Hodge Nonselective suppression of operant ethanol and sucrose self-administration by the mGluR7 positive allosteric modulator AMN082 Pharmacol Biochem Behav 91 1 2008 14 20
    • (2008) Pharmacol Biochem Behav , vol.91 , Issue.1 , pp. 14-20
    • Salling, M.C.1    Faccidomo, S.2    Hodge, C.W.3
  • 323
    • 79955405349 scopus 로고    scopus 로고
    • Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption in alcohol-preferring rats
    • Y. Sari, M. Sakai, J.M. Weedman, G.V. Rebec, and R.L. Bell Ceftriaxone, a beta-lactam antibiotic, reduces ethanol consumption in alcohol-preferring rats Alcohol Alcohol 46 3 2011 239 246
    • (2011) Alcohol Alcohol , vol.46 , Issue.3 , pp. 239-246
    • Sari, Y.1    Sakai, M.2    Weedman, J.M.3    Rebec, G.V.4    Bell, R.L.5
  • 324
    • 67651151209 scopus 로고    scopus 로고
    • Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats. The Journal of Neuroscience, 29(29), 9239-9243. Reductions in cue- and heroin-induced drug-seeking
    • Y. Sari, K.D. Smith, P.K. Ali, and G.V. Rebec Upregulation of GLT1 attenuates cue-induced reinstatement of cocaine-seeking behavior in rats. The Journal of Neuroscience, 29(29), 9239-9243. reductions in cue- and heroin-induced drug-seeking Biol Psychiatry 63 3 2009 338 340
    • (2009) Biol Psychiatry , vol.63 , Issue.3 , pp. 338-340
    • Sari, Y.1    Smith, K.D.2    Ali, P.K.3    Rebec, G.V.4
  • 325
    • 0028207306 scopus 로고
    • Cloning and expression of a new member of the l-2-amino-4- phosphonobutyric acid-sensitive class of metabotropic glutamate receptors
    • J.A. Saugstad, J.M. Kinzie, E.R. Mulvihill, T.P. Segerson, and G.L. Westbrook Cloning and expression of a new member of the l-2-amino-4- phosphonobutyric acid-sensitive class of metabotropic glutamate receptors Mol Pharmacol 45 3 1994 367 372
    • (1994) Mol Pharmacol , vol.45 , Issue.3 , pp. 367-372
    • Saugstad, J.A.1    Kinzie, J.M.2    Mulvihill, E.R.3    Segerson, T.P.4    Westbrook, G.L.5
  • 326
    • 30744459586 scopus 로고    scopus 로고
    • Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity
    • DOI 10.1016/j.neuropharm.2005.08.002, PII S0028390805003060
    • S. Schmid, and M. Fendt Effects of the mGluR8 agonist (S)-3,4-DCPG in the lateral amygdala on acquisition/expression of fear-potentiated startle, synaptic transmission, and plasticity Neuropharmacology 50 2 2006 154 164 (Pubitemid 43100001)
    • (2006) Neuropharmacology , vol.50 , Issue.2 , pp. 154-164
    • Schmid, S.1    Fendt, M.2
  • 327
    • 77949303420 scopus 로고    scopus 로고
    • Cocaine-induced neuroadaptations in glutamate transmission: Potential therapeutic targets for craving and addiction
    • H.D. Schmidt, and R.C. Pierce Cocaine-induced neuroadaptations in glutamate transmission: potential therapeutic targets for craving and addiction Ann N Y Acad Sci 1187 2010 35 75
    • (2010) Ann N y Acad Sci , vol.1187 , pp. 35-75
    • Schmidt, H.D.1    Pierce, R.C.2
  • 328
    • 0034811597 scopus 로고    scopus 로고
    • Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
    • D.D. Schoepp Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system J Pharmacol Exp Ther 299 1 2001 12 20 (Pubitemid 32905113)
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.299 , Issue.1 , pp. 12-20
    • Schoepp, D.D.1
  • 330
    • 17744365745 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats
    • DOI 10.1007/s00213-005-2175-9
    • J.P. Schroeder, D.H. Overstreet, and C.W. Hodge The mGluR5 antagonist MPEP decreases operant ethanol self-administration during maintenance and after repeated alcohol deprivations in alcohol-preferring (P) rats Psychopharmacology (Berl) 179 1 2005 262 270 (Pubitemid 40576714)
    • (2005) Psychopharmacology , vol.179 , Issue.1 , pp. 262-270
    • Schroeder, J.P.1    Overstreet, D.H.2    Hodge, C.W.3
  • 331
    • 0033710845 scopus 로고    scopus 로고
    • Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors
    • A. Semyanov, and D.M. Kullmann Modulation of GABAergic signaling among interneurons by metabotropic glutamate receptors Neuron 25 3 2000 663 672
    • (2000) Neuron , vol.25 , Issue.3 , pp. 663-672
    • Semyanov, A.1    Kullmann, D.M.2
  • 332
    • 37349093371 scopus 로고    scopus 로고
    • Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice
    • DOI 10.1111/j.1530-0277.2007.00554.x
    • A.C. Sharko, and C.W. Hodge Differential modulation of ethanol-induced sedation and hypnosis by metabotropic glutamate receptor antagonists in C57BL/6J mice Alcohol Clin Exp Res 32 1 2008 67 76 (Pubitemid 350293899)
    • (2008) Alcoholism: Clinical and Experimental Research , vol.32 , Issue.1 , pp. 67-76
    • Sharko, A.C.1    Hodge, C.W.2
  • 333
    • 0036198356 scopus 로고    scopus 로고
    • Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo
    • E.F. Sharpe, A.E. Kingston, D. Lodge, J.A. Monn, and P.M. Headley Systemic pre-treatment with a group II mGlu agonist, LY379268, reduces hyperalgesia in vivo Br J Pharmacol 135 5 2002 1255 1262 (Pubitemid 34259128)
    • (2002) British Journal of Pharmacology , vol.135 , Issue.5 , pp. 1255-1262
    • Sharpe, E.F.1    Kingston, A.E.2    Lodge, D.3    Monn, J.A.4    Headley, P.M.5
  • 337
    • 0036174757 scopus 로고    scopus 로고
    • Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice
    • DOI 10.1016/S0168-0102(01)00308-X, PII S016801020100308X
    • F. Shutoh, A. Katoh, H. Kitazawa, A. Aiba, S. Itohara, and S. Nagao Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice Neurosci Res 42 2 2002 141 145 (Pubitemid 34155371)
    • (2002) Neuroscience Research , vol.42 , Issue.2 , pp. 141-145
    • Shutoh, F.1    Katoh, A.2    Kitazawa, H.3    Aiba, A.4    Itohara, S.5    Nagao, S.6
  • 338
    • 77950357306 scopus 로고    scopus 로고
    • Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence
    • N. Sidhpura, F. Weiss, and R. Martin-Fardon Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence Biol Psychiatry 67 9 2010 804 811
    • (2010) Biol Psychiatry , vol.67 , Issue.9 , pp. 804-811
    • Sidhpura, N.1    Weiss, F.2    Martin-Fardon, R.3
  • 339
    • 84856981796 scopus 로고    scopus 로고
    • MGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior
    • C.M. Sinclair, R.M. Cleva, L.E. Hood, M.F. Olive, and J.T. Gass mGluR5 receptors in the basolateral amygdala and nucleus accumbens regulate cue-induced reinstatement of ethanol-seeking behavior Pharmacol Biochem Behav 101 3 2012 329 335
    • (2012) Pharmacol Biochem Behav , vol.101 , Issue.3 , pp. 329-335
    • Sinclair, C.M.1    Cleva, R.M.2    Hood, L.E.3    Olive, M.F.4    Gass, J.T.5
  • 340
    • 0033911839 scopus 로고    scopus 로고
    • Ventral pallidal extracellular fluid levels of dopamine, serotonin, gamma amino butyric acid, and glutamate during cocaine self-administration in rats
    • DOI 10.1007/s002130000456
    • G.M. Sizemore, C. Co, and J.E. Smith Ventral pallidal extracellular fluid levels of dopamine, serotonin, gamma amino butyric acid, and glutamate during cocaine self-administration in rats Psychopharmacology (Berl) 150 4 2000 391 398 (Pubitemid 30470217)
    • (2000) Psychopharmacology , vol.150 , Issue.4 , pp. 391-398
    • Sizemore, G.M.1    Co, C.2    Smith, J.E.3
  • 343
    • 84872152569 scopus 로고    scopus 로고
    • Anxiolytic- but not antidepressant-like activity of lu AF21934, a novel, selective positive allosteric modulator of the mGlu(4) receptor
    • A. Slawinska, J.M. Wieronska, K. Stachowicz, A. Palucha-Poniewiera, M.A. Uberti, and M.A. Bacolod et al. Anxiolytic- but not antidepressant-like activity of lu AF21934, a novel, selective positive allosteric modulator of the mGlu(4) receptor Neuropharmacology 66 2013 225 235
    • (2013) Neuropharmacology , vol.66 , pp. 225-235
    • Slawinska, A.1    Wieronska, J.M.2    Stachowicz, K.3    Palucha-Poniewiera, A.4    Uberti, M.A.5    Bacolod, M.A.6
  • 344
    • 0036714011 scopus 로고    scopus 로고
    • Regulation of the retinal bipolar cell mGluR6 pathway by calcineurin
    • J. Snellman, and S. Nawy Regulation of the retinal bipolar cell mGluR6 pathway by calcineurin J Neurophysiol 88 3 2002 1088 1096 (Pubitemid 35025364)
    • (2002) Journal of Neurophysiology , vol.88 , Issue.3 , pp. 1088-1096
    • Snellman, J.1    Nawy, S.2
  • 345
    • 0035397917 scopus 로고    scopus 로고
    • 5 receptors and CNS disorders
    • DOI 10.1016/S0165-6147(00)01694-1, PII S0165614700016941
    • W.P. Spooren, F. Gasparini, T.E. Salt, and R. Kuhn Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders Trends Pharmacol Sci 22 7 2001 331 337 (Pubitemid 32592465)
    • (2001) Trends in Pharmacological Sciences , vol.22 , Issue.7 , pp. 331-337
    • Spooren, W.P.J.M.1    Gasparini, F.2    Salt, T.E.3    Kuhn, R.4
  • 346
    • 0033680311 scopus 로고    scopus 로고
    • Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine in rodents
    • W.P. Spooren, A. Vassout, H.C. Neijt, R. Kuhn, F. Gasparini, and S. Roux et al. Anxiolytic-like effects of the prototypical metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine in rodents J Pharmacol Exp Ther 295 3 2000 1267 1275
    • (2000) J Pharmacol Exp Ther , vol.295 , Issue.3 , pp. 1267-1275
    • Spooren, W.P.1    Vassout, A.2    Neijt, H.C.3    Kuhn, R.4    Gasparini, F.5    Roux, S.6
  • 350
    • 0035889975 scopus 로고    scopus 로고
    • Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: A potential role for homer
    • C.J. Swanson, D.A. Baker, D. Carson, P.F. Worley, and P.W. Kalivas Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: a potential role for homer J Neurosci 21 22 2001 9043 9052 (Pubitemid 33054866)
    • (2001) Journal of Neuroscience , vol.21 , Issue.22 , pp. 9043-9052
    • Swanson, C.J.1    Baker, D.A.2    Carson, D.3    Worley, P.F.4    Kalivas, P.W.5
  • 352
    • 0034115351 scopus 로고    scopus 로고
    • Impaired behavioral suppression by light in metabotropic glutamate receptor subtype 6-deficient mice
    • DOI 10.1016/S0306-4522(00)00053-1, PII S0306452200000531
    • M. Takao, K. Morigiwa, H. Sasaki, T. Miyoshi, T. Shima, and S. Nakanishi et al. Impaired behavioral suppression by light in metabotropic glutamate receptor subtype 6-deficient mice Neuroscience 97 4 2000 779 787 (Pubitemid 30332186)
    • (2000) Neuroscience , vol.97 , Issue.4 , pp. 779-787
    • Takao, M.1    Morigiwa, K.2    Sasaki, H.3    Miyoshi, T.4    Shima, T.5    Nakanishi, S.6    Nagai, K.7    Fukuda, Y.8
  • 353
    • 0035960059 scopus 로고    scopus 로고
    • Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: Differential location relative to pre- and postsynaptic sites
    • DOI 10.1016/S0306-4522(01)00305-0, PII S0306452201003050
    • Y. Tamaru, S. Nomura, N. Mizuno, and R. Shigemoto Distribution of metabotropic glutamate receptor mGluR3 in the mouse CNS: differential location relative to pre- and postsynaptic sites Neuroscience 106 3 2001 481 503 (Pubitemid 32925240)
    • (2001) Neuroscience , vol.106 , Issue.3 , pp. 481-503
    • Tamaru, Y.1    Nomura, S.2    Mizuno, N.3    Shigemoto, R.4
  • 354
  • 355
    • 0034795826 scopus 로고    scopus 로고
    • The antianxiety-like effects of antagonists of group i and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration
    • E. Tatarczynska, A. Klodzinska, B. Kroczka, E. Chojnacka-Wojcik, and A. Pilc The antianxiety-like effects of antagonists of group I and agonists of group II and III metabotropic glutamate receptors after intrahippocampal administration Psychopharmacology (Berl) 158 1 2001 94 99
    • (2001) Psychopharmacology (Berl) , vol.158 , Issue.1 , pp. 94-99
    • Tatarczynska, E.1    Klodzinska, A.2    Kroczka, B.3    Chojnacka-Wojcik, E.4    Pilc, A.5
  • 356
    • 0036971043 scopus 로고    scopus 로고
    • Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats
    • E. Tatarczynska, A. Palucha, B. Szewczyk, E. Chojnacka-Wojcik, J. Wieronska, and A. Pilc Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4- tricarboxylic acid (ACPT-I) in rats Pol J Pharmacol 54 6 2002 707 710 (Pubitemid 36124524)
    • (2002) Polish Journal of Pharmacology , vol.54 , Issue.6 , pp. 707-710
    • Tatarczynska, E.1    Palucha, A.2    Szewczyk, B.3    Chojnacka-Wojcik, E.4    Wieronska, J.5    Pilc, A.6
  • 357
    • 0037444442 scopus 로고    scopus 로고
    • Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity
    • D.L. Taylor, L.T. Diemel, and J.M. Pocock Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity J Neurosci 23 6 2003 2150 2160 (Pubitemid 36368903)
    • (2003) Journal of Neuroscience , vol.23 , Issue.6 , pp. 2150-2160
    • Taylor, D.L.1    Diemel, L.T.2    Pocock, J.M.3
  • 358
    • 19244387486 scopus 로고    scopus 로고
    • Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking
    • DOI 10.1016/j.ejphar.2004.07.056, PII S0014299904007885
    • M. Tessari, M. Pilla, M. Andreoli, D.M. Hutcheson, and C.A. Heidbreder Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking Eur J Pharmacol 499 1-2 2004 121 133 (Pubitemid 39201219)
    • (2004) European Journal of Pharmacology , vol.499 , Issue.1-2 , pp. 121-133
    • Tessari, M.1    Pilla, M.2    Andreoli, M.3    Hutcheson, D.M.4    Heidbreder, C.A.5
  • 359
    • 0030174952 scopus 로고    scopus 로고
    • α-Methyl derivatives of serin-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists
    • DOI 10.1016/S0028-3908(96)00019-6
    • N.K. Thomas, D.E. Jane, H. Tse, and J.C. Watkins (Alpha)-methyl derivatives of serin-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists Neuropharmacology 35 6 1996 637 642 (Pubitemid 26308540)
    • (1996) Neuropharmacology , vol.35 , Issue.6 , pp. 637-642
    • Thomas, N.K.1    Jane, D.E.2    Tse, H.-W.3    Watkins, J.C.4
  • 360
    • 0035136627 scopus 로고    scopus 로고
    • (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord
    • DOI 10.1016/S0028-3908(00)00169-6, PII S0028390800001696
    • N.K. Thomas, R.A. Wright, P.A. Howson, A.E. Kingston, D.D. Schoepp, and D.E. Jane (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord Neuropharmacology 40 3 2001 311 318 (Pubitemid 32144709)
    • (2001) Neuropharmacology , vol.40 , Issue.3 , pp. 311-318
    • Thomas, N.K.1    Wright, R.A.2    Howson, P.A.3    Kingston, A.E.4    Schoepp, D.D.5    Jane, D.E.6
  • 361
    • 0029097032 scopus 로고
    • Induction or protection of limbic seizures in mice by mGluR subtype selective agonists
    • J.P. Tizzano, K.I. Griffey, and D.D. Schoepp Induction or protection of limbic seizures in mice by mGluR subtype selective agonists Neuropharmacology 34 8 1995 1063 1067
    • (1995) Neuropharmacology , vol.34 , Issue.8 , pp. 1063-1067
    • Tizzano, J.P.1    Griffey, K.I.2    Schoepp, D.D.3
  • 362
    • 0029966777 scopus 로고    scopus 로고
    • The effects of (RS)-α-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist
    • N.J. Toms, D.E. Jane, M.C. Kemp, J.S. Bedingfield, and P.J. Roberts The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist Br J Pharmacol 119 5 1996 851 854 (Pubitemid 26366477)
    • (1996) British Journal of Pharmacology , vol.119 , Issue.5 , pp. 851-854
    • Toms, N.J.1    Jane, D.E.2    Kemp, M.C.3    Bedingfield, J.S.4    Roberts, P.J.5
  • 363
    • 84881431286 scopus 로고    scopus 로고
    • Initial human PET studies of metabotropic glutamate receptor type 1 ligand 11C-ITMM
    • J. Toyohara, M. Sakata, K. Oda, K. Ishii, K. Ito, and M. Hiura et al. Initial human PET studies of metabotropic glutamate receptor type 1 ligand 11C-ITMM J Nucl Med 54 8 2013 1302 1307
    • (2013) J Nucl Med , vol.54 , Issue.8 , pp. 1302-1307
    • Toyohara, J.1    Sakata, M.2    Oda, K.3    Ishii, K.4    Ito, K.5    Hiura, M.6
  • 364
    • 77955572024 scopus 로고    scopus 로고
    • The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)- pyridine (MPEP) on behavioural responses to nicotine
    • V. Tronci, S. Vronskaya, N. Montgomery, D. Mura, and D.J. Balfour The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine Psychopharmacology (Berl) 211 1 2010 33 42
    • (2010) Psychopharmacology (Berl) , vol.211 , Issue.1 , pp. 33-42
    • Tronci, V.1    Vronskaya, S.2    Montgomery, N.3    Mura, D.4    Balfour, D.J.5
  • 365
    • 0038290732 scopus 로고    scopus 로고
    • Glutamatergic mechanisms in addiction
    • DOI 10.1038/sj.mp.4001269
    • T.M. Tzschentke, and W.J. Schmidt Glutamatergic mechanisms in addiction Mol Psychiatry 8 4 2003 373 382 (Pubitemid 36609661)
    • (2003) Molecular Psychiatry , vol.8 , Issue.4 , pp. 373-382
    • Tzschentke, T.M.1    Schmidt, W.J.2
  • 366
    • 79953899942 scopus 로고    scopus 로고
    • Allosteric modulation of family C G-protein-coupled receptors: From molecular insights to therapeutic perspectives
    • S. Urwyler Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives Pharmacol Rev 63 1 2011 59 126
    • (2011) Pharmacol Rev , vol.63 , Issue.1 , pp. 59-126
    • Urwyler, S.1
  • 367
    • 69649104858 scopus 로고    scopus 로고
    • Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus
    • J.M. Uslaner, S. Parmentier-Batteur, R.B. Flick, N.O. Surles, J.S. Lam, and C.H. McNaughton et al. Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus Neuropharmacology 57 5-6 2009 531 538
    • (2009) Neuropharmacology , vol.57 , Issue.56 , pp. 531-538
    • Uslaner, J.M.1    Parmentier-Batteur, S.2    Flick, R.B.3    Surles, N.O.4    Lam, J.S.5    McNaughton, C.H.6
  • 368
    • 0035834979 scopus 로고    scopus 로고
    • Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina
    • DOI 10.1016/S0378-1119(00)00547-3, PII S0378111900005473
    • A. Valerio, S. Ferraboli, M. Paterlini, P. Spano, and S. Barlati Identification of novel alternatively-spliced mRNA isoforms of metabotropic glutamate receptor 6 gene in rat and human retina Gene 262 1-2 2001 99 106 (Pubitemid 32155339)
    • (2001) Gene , vol.262 , Issue.1-2 , pp. 99-106
    • Valerio, A.1    Ferraboli, S.2    Paterlini, M.3    Spano, P.4    Barlati, S.5
  • 369
    • 0032968641 scopus 로고    scopus 로고
    • The selective mGlu2/3 receptor agonist LY354740 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal
    • DOI 10.1016/S0028-3908(98)00196-8, PII S0028390898001968
    • J. Vandergriff, and K. Rasmussen The selective mGlu2/3 receptor agonist LY354740 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioral signs of morphine withdrawal Neuropharmacology 38 2 1999 217 222 (Pubitemid 29073541)
    • (1999) Neuropharmacology , vol.38 , Issue.2 , pp. 217-222
    • Vandergriff, J.1    Rasmussen, K.2
  • 372
    • 79953658275 scopus 로고    scopus 로고
    • Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine
    • M.M. Veeneman, H. Boleij, M.H. Broekhoven, E.M. Snoeren, M.G. Masip, and J. Cousijn et al. Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine Psychopharmacology (Berl) 214 4 2011 863 876
    • (2011) Psychopharmacology (Berl) , vol.214 , Issue.4 , pp. 863-876
    • Veeneman, M.M.1    Boleij, H.2    Broekhoven, M.H.3    Snoeren, E.M.4    Masip, M.G.5    Cousijn, J.6
  • 373
    • 0038273909 scopus 로고    scopus 로고
    • Positron emission tomography and single-photon emission computed tomography in substance abuse research
    • DOI 10.1053/snuc.2003.127300
    • N.D. Volkow, J.S. Fowler, and G.J. Wang Positron emission tomography and single-photon emission computed tomography in substance abuse research Semin Nucl Med 33 2 2003 114 128 (Pubitemid 36577054)
    • (2003) Seminars in Nuclear Medicine , vol.33 , Issue.2 , pp. 114-128
    • Volkow, N.D.1    Fowler, J.S.2    Wang, G.-J.3
  • 374
    • 84871791218 scopus 로고    scopus 로고
    • Role of mGluR5 neurotransmission in reinstated cocaine-seeking
    • X. Wang, K. Moussawi, L. Knackstedt, H. Shen, and P.W. Kalivas Role of mGluR5 neurotransmission in reinstated cocaine-seeking Addict Biol 18 1 2013 40 49
    • (2013) Addict Biol , vol.18 , Issue.1 , pp. 40-49
    • Wang, X.1    Moussawi, K.2    Knackstedt, L.3    Shen, H.4    Kalivas, P.W.5
  • 375
    • 78651282657 scopus 로고    scopus 로고
    • Participation of metabotropic glutamate receptors in pentetrazol-induced kindled seizure
    • Y. Watanabe, Y. Kaida, S. Fukuhara, K. Takechi, T. Uehara, and C. Kamei Participation of metabotropic glutamate receptors in pentetrazol-induced kindled seizure Epilepsia 52 1 2011 140 150
    • (2011) Epilepsia , vol.52 , Issue.1 , pp. 140-150
    • Watanabe, Y.1    Kaida, Y.2    Fukuhara, S.3    Takechi, K.4    Uehara, T.5    Kamei, C.6
  • 376
    • 84870763983 scopus 로고    scopus 로고
    • The mGluR5 positive allosteric modulator CDPPB does not alter extinction or contextual reinstatement of methamphetamine-seeking behavior in rats
    • J.J. Widholm, J.T. Gass, R.M. Cleva, and M.F. Olive The mGluR5 positive allosteric modulator CDPPB does not alter extinction or contextual reinstatement of methamphetamine-seeking behavior in rats J Addict Res Ther S1 4 2011 004
    • (2011) J Addict Res Ther , vol.S1 , Issue.4 , pp. 004
    • Widholm, J.J.1    Gass, J.T.2    Cleva, R.M.3    Olive, M.F.4
  • 377
    • 84878711236 scopus 로고    scopus 로고
    • The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT(1)A signalling
    • J.M. Wieronska, F.C. Acher, A. Slawinska, P. Gruca, M. Lason-Tyburkiewicz, and M. Papp et al. The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT(1)A signalling Psychopharmacology (Berl) 227 4 2013 711 725
    • (2013) Psychopharmacology (Berl) , vol.227 , Issue.4 , pp. 711-725
    • Wieronska, J.M.1    Acher, F.C.2    Slawinska, A.3    Gruca, P.4    Lason-Tyburkiewicz, M.5    Papp, M.6
  • 378
    • 65249100748 scopus 로고    scopus 로고
    • Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus
    • J.M. Wieronska, B. Legutko, D. Dudys, and A. Pilc Olfactory bulbectomy and amitriptyline treatment influences mGlu receptors expression in the mouse brain hippocampus Pharmacol Rep 60 6 2008 844 855
    • (2008) Pharmacol Rep , vol.60 , Issue.6 , pp. 844-855
    • Wieronska, J.M.1    Legutko, B.2    Dudys, D.3    Pilc, A.4
  • 379
    • 64949091023 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs
    • J.M. Wieronska, and A. Pilc Metabotropic glutamate receptors in the tripartite synapse as a target for new psychotropic drugs Neurochem Int 55 1-3 2009 85 97
    • (2009) Neurochem Int , vol.55 , Issue.13 , pp. 85-97
    • Wieronska, J.M.1    Pilc, A.2
  • 380
    • 84858443194 scopus 로고    scopus 로고
    • Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia
    • J.M. Wieronska, K. Stachowicz, F. Acher, T. Lech, and A. Pilc Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia Psychopharmacology (Berl) 220 3 2012 481 494
    • (2012) Psychopharmacology (Berl) , vol.220 , Issue.3 , pp. 481-494
    • Wieronska, J.M.1    Stachowicz, K.2    Acher, F.3    Lech, T.4    Pilc, A.5
  • 381
    • 77958084765 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems
    • J.M. Wierońska, K. Stachowicz, A. Pałucha-Poniewiera, F. Acher, P. Brański, and A. Pilc Metabotropic glutamate receptor 4 novel agonist LSP1-2111 with anxiolytic, but not antidepressant-like activity, mediated by serotonergic and GABAergic systems Neuropharmacology 59 7-8 2010 627 634
    • (2010) Neuropharmacology , vol.59 , Issue.78 , pp. 627-634
    • Wierońska, J.M.1    Stachowicz, K.2    Pałucha-Poniewiera, A.3    Acher, F.4    Brański, P.5    Pilc, A.6
  • 382
    • 68349128341 scopus 로고    scopus 로고
    • Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)
    • R. Williams, K.A. Johnson, P.R. Gentry, C.M. Niswender, C.D. Weaver, and P.J. Conn et al. Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4) Bioorg Med Chem Lett 19 17 2009 4967 4970
    • (2009) Bioorg Med Chem Lett , vol.19 , Issue.17 , pp. 4967-4970
    • Williams, R.1    Johnson, K.A.2    Gentry, P.R.3    Niswender, C.M.4    Weaver, C.D.5    Conn, P.J.6
  • 383
    • 58549097255 scopus 로고    scopus 로고
    • Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-lead
    • R. Williams, C.M. Niswender, Q. Luo, U. Le, P.J. Conn, and C.W. Lindsley Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). part II: challenges in hit-to-lead Bioorg Med Chem Lett 19 3 2009 962 966
    • (2009) Bioorg Med Chem Lett , vol.19 , Issue.3 , pp. 962-966
    • Williams, R.1    Niswender, C.M.2    Luo, Q.3    Le, U.4    Conn, P.J.5    Lindsley, C.W.6
  • 384
    • 0029736874 scopus 로고    scopus 로고
    • Novel glial-neuronal signalling by coactivation of metabotropic glutamate and β-adrenergic receptors in rat hippocampus
    • D.G. Winder, P.S. Ritch, R.W. Gereau 4th, and P.J. Conn Novel glial-neuronal signalling by coactivation of metabotropic glutamate and beta-adrenergic receptors in rat hippocampus J Physiol 494 Pt 3 1996 743 755 (Pubitemid 26278851)
    • (1996) Journal of Physiology , vol.494 , Issue.3 , pp. 743-755
    • Winder, D.G.1    Ritch, P.S.2    Gereau IV, R.W.3    Conn, P.J.4
  • 385
    • 78049279275 scopus 로고    scopus 로고
    • Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine
    • M.E. Wolf Regulation of AMPA receptor trafficking in the nucleus accumbens by dopamine and cocaine Neurotox Res 18 3-4 2010 393 409
    • (2010) Neurotox Res , vol.18 , Issue.34 , pp. 393-409
    • Wolf, M.E.1
  • 386
    • 77953811099 scopus 로고    scopus 로고
    • AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine
    • M.E. Wolf, and C.R. Ferrario AMPA receptor plasticity in the nucleus accumbens after repeated exposure to cocaine Neurosci Biobehav Rev 35 2 2010 185 211
    • (2010) Neurosci Biobehav Rev , vol.35 , Issue.2 , pp. 185-211
    • Wolf, M.E.1    Ferrario, C.R.2
  • 388
    • 0030024591 scopus 로고    scopus 로고
    • Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus
    • DOI 10.1016/0014-2999(95)00747-4
    • R.A. Wright, and D.D. Schoepp Differentiation of group 2 and group 3 metabotropic glutamate receptor cAMP responses in the rat hippocampus Eur J Pharmacol 297 3 1996 275 282 (Pubitemid 26066822)
    • (1996) European Journal of Pharmacology , vol.297 , Issue.3 , pp. 275-282
    • Wright, R.A.1    Schoepp, D.D.2
  • 389
    • 0031950950 scopus 로고    scopus 로고
    • Group III human metabotropic glutamate receptors 4, 7 and 8: Molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells
    • DOI 10.1016/S0169-328X(97)00277-5, PII S0169328X97002775
    • S. Wu, R.A. Wright, P.K. Rockey, S.G. Burgett, J.S. Arnold, and P.R. Rosteck Jr. et al. Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells Mol Brain Res 53 1-2 1998 88 97 (Pubitemid 28085445)
    • (1998) Molecular Brain Research , vol.53 , Issue.1-2 , pp. 88-97
    • Wu, S.1    Wright, R.A.2    Rockey, P.K.3    Burgett, S.G.4    Arnold, J.S.5    Rosteck Jr., P.R.6    Johnson, B.G.7    Schoepp, D.D.8    Belagaje, R.M.9
  • 390
    • 84874420673 scopus 로고    scopus 로고
    • Accumbal and pallidal dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction in rats
    • K. Wydra, K. Golembiowska, M. Zaniewska, K. Kaminska, L. Ferraro, and K. Fuxe et al. Accumbal and pallidal dopamine, glutamate and GABA overflow during cocaine self-administration and its extinction in rats Addict Biol 18 2 2013 307 324
    • (2013) Addict Biol , vol.18 , Issue.2 , pp. 307-324
    • Wydra, K.1    Golembiowska, K.2    Zaniewska, M.3    Kaminska, K.4    Ferraro, L.5    Fuxe, K.6
  • 393
    • 0345305832 scopus 로고    scopus 로고
    • Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens
    • DOI 10.1046/j.1471-4159.2003.02093.x
    • Z.X. Xi, H. Shen, D.A. Baker, and P.W. Kalivas Inhibition of non-vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens J Neurochem 87 5 2003 1204 1212 (Pubitemid 37485076)
    • (2003) Journal of Neurochemistry , vol.87 , Issue.5 , pp. 1204-1212
    • Xi, Z.-X.1    Shen, H.2    Baker, D.A.3    Kalivas, P.W.4
  • 394
    • 84861409529 scopus 로고    scopus 로고
    • Differences in rat dorsal striatal NMDA and AMPA receptors following acute and repeated cocaine-induced locomotor activation
    • D.J. Yamamoto, and N.R. Zahniser Differences in rat dorsal striatal NMDA and AMPA receptors following acute and repeated cocaine-induced locomotor activation PLoS One 7 5 2012 e37673
    • (2012) PLoS One , vol.7 , Issue.5 , pp. 37673
    • Yamamoto, D.J.1    Zahniser, N.R.2
  • 395
    • 72049099358 scopus 로고    scopus 로고
    • Nicotine-induced conditioned place preference in rats: Sex differences and the role of mGluR5 receptors
    • G. Yararbas, A. Keser, L. Kanit, and S. Pogun Nicotine-induced conditioned place preference in rats: sex differences and the role of mGluR5 receptors Neuropharmacology 58 2 2010 374 382
    • (2010) Neuropharmacology , vol.58 , Issue.2 , pp. 374-382
    • Yararbas, G.1    Keser, A.2    Kanit, L.3    Pogun, S.4
  • 397
    • 34548023703 scopus 로고    scopus 로고
    • Night blindness-associated mutations in the ligand-binding, cysteine-rich, and intracellular domains of the metabotropic glutamate receptor 6 abolish protein trafficking
    • DOI 10.1002/humu.20499
    • C. Zeitz, U. Forster, J. Neidhardt, S. Feil, S. Kalin, and D. Leifert et al. Night blindness-associated mutations in the ligand-binding, cysteine-rich,
    • (2007) Human Mutation , vol.28 , Issue.8 , pp. 771-780
    • Zeitz, C.1    Forster, U.2    Neidhardt, J.3    Feil, S.4    Kalin, S.5    Leifert, D.6    Flor, P.J.7    Berger, W.8
  • 398
    • 0037209247 scopus 로고    scopus 로고
    • Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex
    • Y. Zhai, C.A. George, J. Zhai, E.S. Nisenbaum, M.P. Johnson, and L.K. Nisenbaum Group II metabotropic glutamate receptor modulation of DOI-induced c-fos mRNA and excitatory responses in the cerebral cortex Neuropsychopharmacology 28 1 2003 45 52
    • (2003) Neuropsychopharmacology , vol.28 , Issue.1 , pp. 45-52
    • Zhai, Y.1    George, C.A.2    Zhai, J.3    Nisenbaum, E.S.4    Johnson, M.P.5    Nisenbaum, L.K.6
  • 399
    • 33749166779 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala
    • DOI 10.1523/JNEUROSCI.2384-06.2006
    • Y. Zhao, C.V. Dayas, H. Aujla, M.A. Baptista, R. Martin-Fardon, and F. Weiss Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala J Neurosci 26 39 2006 9967 9974 (Pubitemid 44477158)
    • (2006) Journal of Neuroscience , vol.26 , Issue.39 , pp. 9967-9974
    • Zhao, Y.1    Dayas, C.V.2    Aujla, H.3    Baptista, M.A.S.4    Martin-Fardon, R.5    Weiss, F.6
  • 400
    • 84961394503 scopus 로고    scopus 로고
    • N-Acetylcysteine reduces extinction responding and induces enduring Bahi, A. (2012). The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 prevents reinstatement of extinguished ethanol-induced conditioned place preference in mice
    • W. Zhou, and P.W. Kalivas N-Acetylcysteine reduces extinction responding and induces enduring Bahi, A. (2012). The selective metabotropic glutamate receptor 7 allosteric agonist AMN082 prevents reinstatement of extinguished ethanol-induced conditioned place preference in mice Pharmacol Biochem Behav 101 2 2008 193 200
    • (2008) Pharmacol Biochem Behav , vol.101 , Issue.2 , pp. 193-200
    • Zhou, W.1    Kalivas, P.W.2
  • 401
    • 77249122078 scopus 로고    scopus 로고
    • Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons
    • J. Zou, Y.X. Wang, F.F. Dou, H.Z. Lu, Z.W. Ma, and P.H. Lu et al. Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons Neurochem Int 56 4 2010 577 584
    • (2010) Neurochem Int , vol.56 , Issue.4 , pp. 577-584
    • Zou, J.1    Wang, Y.X.2    Dou, F.F.3    Lu, H.Z.4    Ma, Z.W.5    Lu, P.H.6
  • 402
    • 84961404756 scopus 로고    scopus 로고
    • www.ncbi.nlm.nih.gov/homologene


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