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Volumn 110, Issue 2, 2013, Pages 737-742

Marked global reduction in mGluR5 receptor binding in smokers and ex-smokers determined by [11C]ABP688 positron emission tomography

Author keywords

Caudate; Relapse; Substance use disorders; Thalamus

Indexed keywords

3 (6 METHYLPYRIDIN 2 YLETHYNYL) CYCLOHEX 2 ENONE O CARBON 11 METHYL OXIME; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

EID: 84872186347     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1210984110     Document Type: Article
Times cited : (97)

References (56)
  • 1
    • 17644374100 scopus 로고    scopus 로고
    • The neural basis of addiction: A pathology of motivation and choice
    • Kalivas PW, Volkow ND (2005) The neural basis of addiction: A pathology of motivation and choice. Am J Psychiatry 162(8):1403-1413.
    • (2005) Am J Psychiatry , vol.162 , Issue.8 , pp. 1403-1413
    • Kalivas, P.W.1    Volkow, N.D.2
  • 2
    • 70349782435 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor ligands as potential therapeutics for addiction
    • Olive MF (2009) Metabotropic glutamate receptor ligands as potential therapeutics for addiction. Curr Drug Abuse Rev 2(1):83-98.
    • (2009) Curr Drug Abuse Rev , vol.2 , Issue.1 , pp. 83-98
    • Olive, M.F.1
  • 3
    • 0034867765 scopus 로고    scopus 로고
    • Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice
    • Chiamulera C, et al. (2001) Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice. Nat Neurosci 4(9):873-874.
    • (2001) Nat Neurosci , vol.4 , Issue.9 , pp. 873-874
    • Chiamulera, C.1
  • 4
    • 0345830608 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats
    • Kenny PJ, et al. (2003) Metabotropic glutamate 5 receptor antagonist MPEP decreased nicotine and cocaine self-administration but not nicotine and cocaine-induced facilitation of brain reward function in rats. Ann N Y Acad Sci 1003:415-418.
    • (2003) Ann N Y Acad Sci , vol.1003 , pp. 415-418
    • Kenny, P.J.1
  • 5
    • 0038240644 scopus 로고    scopus 로고
    • The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice
    • Paterson NE, Semenova S, Gasparini F, Markou A (2003) The mGluR5 antagonist MPEP decreased nicotine self-administration in rats and mice. Psychopharmacology (Berl) 167(3):257-264.
    • (2003) Psychopharmacology (Berl) , vol.167 , Issue.3 , pp. 257-264
    • Paterson, N.E.1    Semenova, S.2    Gasparini, F.3    Markou, A.4
  • 6
    • 19244387486 scopus 로고    scopus 로고
    • Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking
    • Tessari M, Pilla M, Andreoli M, Hutcheson DM, Heidbreder CA (2004) Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking. Eur J Pharmacol 499(1-2):121-133.
    • (2004) Eur J Pharmacol , vol.499 , Issue.1-2 , pp. 121-133
    • Tessari, M.1    Pilla, M.2    Andreoli, M.3    Hutcheson, D.M.4    Heidbreder, C.A.5
  • 7
    • 23644451337 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats
    • Bespalov AY, et al. (2005) Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats. Neuropharmacology 49(Suppl 1):167-178.
    • (2005) Neuropharmacology , vol.49 , Issue.SUPPL. 1 , pp. 167-178
    • Bespalov, A.Y.1
  • 8
    • 17744400697 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats
    • Kenny PJ, Boutrel B, Gasparini F, Koob GF, Markou A (2005) Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology (Berl) 179(1):247-254.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 247-254
    • Kenny, P.J.1    Boutrel, B.2    Gasparini, F.3    Koob, G.F.4    Markou, A.5
  • 9
    • 14344261021 scopus 로고    scopus 로고
    • Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: Comparison with dizocilpine
    • Lee B, Platt DM, Rowlett JK, Adewale AS, Spealman RD (2005) Attenuation of behavioral effects of cocaine by the Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)-pyridine in squirrel monkeys: Comparison with dizocilpine. J Pharmacol Exp Ther 312(3):1232-1240.
    • (2005) J Pharmacol Exp Ther , vol.312 , Issue.3 , pp. 1232-1240
    • Lee, B.1    Platt, D.M.2    Rowlett, J.K.3    Adewale, A.S.4    Spealman, R.D.5
  • 10
    • 35948936012 scopus 로고    scopus 로고
    • Effect of 2-methyl-6-(phenylethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat
    • van der Kam EL, de Vry J, Tzschentke TM (2007) Effect of 2-methyl-6-(phenylethynyl) pyridine on intravenous self-administration of ketamine and heroin in the rat. Behav Pharmacol 18(8):717-724.
    • (2007) Behav Pharmacol , vol.18 , Issue.8 , pp. 717-724
    • Van Der Kam, E.L.1    De Vry, J.2    Tzschentke, T.M.3
  • 11
    • 33745067266 scopus 로고    scopus 로고
    • Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5
    • Ametamey SM, et al. (2006) Radiosynthesis and preclinical evaluation of 11C-ABP688 as a probe for imaging the metabotropic glutamate receptor subtype 5. J Nucl Med 47(4):698-705.
    • (2006) J Nucl Med , vol.47 , Issue.4 , pp. 698-705
    • Ametamey, S.M.1
  • 12
    • 79953658275 scopus 로고    scopus 로고
    • Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine
    • Veeneman MM, et al. (2011) Dissociable roles of mGlu5 and dopamine receptors in the rewarding and sensitizing properties of morphine and cocaine. Psychopharmacology (Berl) 214(4):863-876.
    • (2011) Psychopharmacology (Berl) , vol.214 , Issue.4 , pp. 863-876
    • Veeneman, M.M.1
  • 13
    • 17744383991 scopus 로고    scopus 로고
    • The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats
    • Paterson NE, Markou A (2005) The metabotropic glutamate receptor 5 antagonist MPEP decreased break points for nicotine, cocaine and food in rats. Psychopharmacology (Berl) 179(1):255-261.
    • (2005) Psychopharmacology (Berl) , vol.179 , Issue.1 , pp. 255-261
    • Paterson, N.E.1    Markou, A.2
  • 14
    • 47249104677 scopus 로고    scopus 로고
    • Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine
    • Palmatier MI, Liu X, Donny EC, Caggiula AR, Sved AF (2008) Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine. Neuropsychopharmacology 33(9):2139-2147.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.9 , pp. 2139-2147
    • Palmatier, M.I.1    Liu, X.2    Donny, E.C.3    Caggiula, A.R.4    Sved, A.F.5
  • 15
    • 0036181180 scopus 로고    scopus 로고
    • Nicotine potentiation of brain stimulation reward reversed by DH beta e and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats
    • Harrison AA, Gasparini F, Markou A (2002) Nicotine potentiation of brain stimulation reward reversed by DH beta E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats. Psychopharmacology (Berl) 160(1):56-66.
    • (2002) Psychopharmacology (Berl) , vol.160 , Issue.1 , pp. 56-66
    • Harrison, A.A.1    Gasparini, F.2    Markou, A.3
  • 16
    • 77955688416 scopus 로고    scopus 로고
    • Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: Factor in the transition to dependence
    • Hao Y, Martin-Fardon R, Weiss F (2010) Behavioral and functional evidence of metabotropic glutamate receptor 2/3 and metabotropic glutamate receptor 5 dysregulation in cocaine-escalated rats: Factor in the transition to dependence. Biol Psychiatry 68(3):240-248.
    • (2010) Biol Psychiatry , vol.68 , Issue.3 , pp. 240-248
    • Hao, Y.1    Martin-Fardon, R.2    Weiss, F.3
  • 17
    • 60249091229 scopus 로고    scopus 로고
    • Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration
    • Ghasemzadeh MB, Vasudevan P, Mueller C, Seubert C, Mantsch JR (2009) Neuroadaptations in the cellular and postsynaptic group 1 metabotropic glutamate receptor mGluR5 and Homer proteins following extinction of cocaine self-administration. Neurosci Lett 452(2):167-171.
    • (2009) Neurosci Lett , vol.452 , Issue.2 , pp. 167-171
    • Ghasemzadeh, M.B.1    Vasudevan, P.2    Mueller, C.3    Seubert, C.4    Mantsch, J.R.5
  • 18
    • 36349030361 scopus 로고    scopus 로고
    • Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: A two-species comparison
    • Ary AW, Szumlinski KK (2007) Regional differences in the effects of withdrawal from repeated cocaine upon Homer and glutamate receptor expression: A two-species comparison. Brain Res 1184:295-305.
    • (2007) Brain Res , vol.1184 , pp. 295-305
    • Ary, A.W.1    Szumlinski, K.K.2
  • 19
    • 0035889975 scopus 로고    scopus 로고
    • Repeated cocaine administration attenuates group i metabotropic glutamate receptor-mediated glutamate release and behavioral activation: A potential role for Homer
    • Swanson CJ, Baker DA, Carson D, Worley PF, Kalivas PW (2001) Repeated cocaine administration attenuates group I metabotropic glutamate receptor-mediated glutamate release and behavioral activation: A potential role for Homer. J Neurosci 21 (22):9043-9052.
    • (2001) J Neurosci , vol.21 , Issue.22 , pp. 9043-9052
    • Swanson, C.J.1    Baker, D.A.2    Carson, D.3    Worley, P.F.4    Kalivas, P.W.5
  • 20
    • 33645025963 scopus 로고    scopus 로고
    • Homer isoforms differentially regulate cocaine-induced neuroplasticity
    • Szumlinski KK, et al. (2006) Homer isoforms differentially regulate cocaine-induced neuroplasticity. Neuropsychopharmacology 31(4):768-777.
    • (2006) Neuropsychopharmacology , vol.31 , Issue.4 , pp. 768-777
    • Szumlinski, K.K.1
  • 21
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • Kalivas PW (2009) The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci 10(8):561-572.
    • (2009) Nat Rev Neurosci , vol.10 , Issue.8 , pp. 561-572
    • Kalivas, P.W.1
  • 22
    • 78649948724 scopus 로고    scopus 로고
    • The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats
    • Rutten K, Van Der Kam EL, De Vry J, Bruckmann W, Tzschentke TM (2010) The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates conditioned place preference induced by various addictive and non-addictive drugs in rats. Addict Biol 16(1):108-115.
    • (2010) Addict Biol , vol.16 , Issue.1 , pp. 108-115
    • Rutten, K.1    Van Der Kam, E.L.2    De Vry, J.3    Bruckmann, W.4    Tzschentke, T.M.5
  • 23
    • 77955572024 scopus 로고    scopus 로고
    • The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)- pyridine (MPEP) on behavioural responses to nicotine
    • Tronci V, Vronskaya S, Montgomery N, Mura D, Balfour DJ (2010) The effects of the mGluR5 receptor antagonist 6-methyl-2-(phenylethynyl)-pyridine (MPEP) on behavioural responses to nicotine. Psychopharmacology (Berl) 211(1):33-42.
    • (2010) Psychopharmacology (Berl) , vol.211 , Issue.1 , pp. 33-42
    • Tronci, V.1    Vronskaya, S.2    Montgomery, N.3    Mura, D.4    Balfour, D.J.5
  • 24
    • 79960539531 scopus 로고    scopus 로고
    • Reduced metabotropic glutamate receptor 5 density in major depression determined by [11C]ABP688 PET and postmortem study
    • Deschwanden A, et al. (2011) Reduced metabotropic glutamate receptor 5 density in major depression determined by [11C]ABP688 PET and postmortem study. Am J Psychiatry 168(7):727-734.
    • (2011) Am J Psychiatry , vol.168 , Issue.7 , pp. 727-734
    • Deschwanden, A.1
  • 25
    • 79954937158 scopus 로고    scopus 로고
    • Imaging changes in glutamate transmission in vivo with the metabotropic glutamate receptor 5 tracer [11C] ABP688 and N-acetylcysteine challenge
    • Miyake N, et al. (2011) Imaging changes in glutamate transmission in vivo with the metabotropic glutamate receptor 5 tracer [11C] ABP688 and N-acetylcysteine challenge. Biol Psychiatry 69(9):822-824.
    • (2011) Biol Psychiatry , vol.69 , Issue.9 , pp. 822-824
    • Miyake, N.1
  • 26
    • 0037075602 scopus 로고    scopus 로고
    • Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas
    • Mansvelder HD, Keath JR, McGehee DS (2002) Synaptic mechanisms underlie nicotine-induced excitability of brain reward areas. Neuron 33(6):905-919.
    • (2002) Neuron , vol.33 , Issue.6 , pp. 905-919
    • Mansvelder, H.D.1    Keath, J.R.2    McGehee, D.S.3
  • 27
    • 0033709986 scopus 로고    scopus 로고
    • Long-term potentiation of excitatory inputs to brain reward areas by nicotine
    • Mansvelder HD, McGehee DS (2000) Long-term potentiation of excitatory inputs to brain reward areas by nicotine. Neuron 27(2):349-357.
    • (2000) Neuron , vol.27 , Issue.2 , pp. 349-357
    • Mansvelder, H.D.1    McGehee, D.S.2
  • 28
    • 79953215206 scopus 로고    scopus 로고
    • Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence
    • Counotte DS, et al. (2011) Lasting synaptic changes underlie attention deficits caused by nicotine exposure during adolescence. Nat Neurosci 14(4):417-419.
    • (2011) Nat Neurosci , vol.14 , Issue.4 , pp. 417-419
    • Counotte, D.S.1
  • 29
    • 33744512777 scopus 로고    scopus 로고
    • Functional brain imaging of tobacco use and dependence
    • Brody AL (2006) Functional brain imaging of tobacco use and dependence. J Psychiatr Res 40(5):404-418.
    • (2006) J Psychiatr Res , vol.40 , Issue.5 , pp. 404-418
    • Brody, A.L.1
  • 30
    • 51449122303 scopus 로고    scopus 로고
    • Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction
    • Everitt BJ, et al. (2008) Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Philos Trans R Soc Lond B Biol Sci 363(1507):3125-3135.
    • (2008) Philos Trans R Soc Lond B Biol Sci , vol.363 , Issue.1507 , pp. 3125-3135
    • Everitt, B.J.1
  • 32
    • 63849311570 scopus 로고    scopus 로고
    • In vivo brain imaging of human exposure to nicotine and tobacco
    • Sharma A, Brody AL (2009) In vivo brain imaging of human exposure to nicotine and tobacco. Handb Exp Pharmacol 192:145-171.
    • (2009) Handb Exp Pharmacol , vol.192 , pp. 145-171
    • Sharma, A.1    Brody, A.L.2
  • 33
    • 0742322858 scopus 로고    scopus 로고
    • Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
    • Battaglia G, et al. (2004) Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. J Neurosci 24(4):828-835.
    • (2004) J Neurosci , vol.24 , Issue.4 , pp. 828-835
    • Battaglia, G.1
  • 34
    • 33645090418 scopus 로고    scopus 로고
    • Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease
    • Armentero MT, Fancellu R, Nappi G, Bramanti P, Blandini F (2006) Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease. Neurobiol Dis 22(1):1-9.
    • (2006) Neurobiol Dis , vol.22 , Issue.1 , pp. 1-9
    • Armentero, M.T.1    Fancellu, R.2    Nappi, G.3    Bramanti, P.4    Blandini, F.5
  • 35
    • 0033842094 scopus 로고    scopus 로고
    • Smoking and Parkinson's and Alzheimer's disease: Review of the epidemiological studies
    • Fratiglioni L, Wang HX (2000) Smoking and Parkinson's and Alzheimer's disease: Review of the epidemiological studies. Behav Brain Res 113(1-2):117-120.
    • (2000) Behav Brain Res , vol.113 , Issue.1-2 , pp. 117-120
    • Fratiglioni, L.1    Wang, H.X.2
  • 36
    • 77957161470 scopus 로고    scopus 로고
    • Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons
    • Grove-Strawser D, Boulware MI, Mermelstein PG (2010) Membrane estrogen receptors activate the metabotropic glutamate receptors mGluR5 and mGluR3 to bidirectionally regulate CREB phosphorylation in female rat striatal neurons. Neuroscience 170(4):1045- 1055.
    • (2010) Neuroscience , vol.170 , Issue.4 , pp. 1045-1055
    • Grove-Strawser, D.1    Boulware, M.I.2    Mermelstein, P.G.3
  • 37
    • 63849298549 scopus 로고    scopus 로고
    • Sex differences in nicotine action
    • Pogun S, Yararbas G (2009) Sex differences in nicotine action. Handb Exp Pharmacol 192:261-291.
    • (2009) Handb Exp Pharmacol , vol.192 , pp. 261-291
    • Pogun, S.1    Yararbas, G.2
  • 38
    • 72049099358 scopus 로고    scopus 로고
    • Nicotine-induced conditioned place preference in rats: Sex differences and the role of mGluR5 receptors
    • Yararbas G, Keser A, Kanit L, Pogun S (2010) Nicotine-induced conditioned place preference in rats: Sex differences and the role of mGluR5 receptors. Neuropharmacology 58(2):374-382.
    • (2010) Neuropharmacology , vol.58 , Issue.2 , pp. 374-382
    • Yararbas, G.1    Keser, A.2    Kanit, L.3    Pogun, S.4
  • 39
    • 77955171213 scopus 로고    scopus 로고
    • In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688
    • Elmenhorst D, et al. (2010) In vivo and in vitro validation of reference tissue models for the mGluR(5) ligand [(11)C]ABP688. J Cereb Blood Flow Metab 30(8):1538-1549.
    • (2010) J Cereb Blood Flow Metab , vol.30 , Issue.8 , pp. 1538-1549
    • Elmenhorst, D.1
  • 40
    • 79955463766 scopus 로고    scopus 로고
    • Quantitation of glutamate mGluR5 receptor with 18F-FPEB PET in humans
    • Barret O, et al. (2010) Quantitation of glutamate mGluR5 receptor with 18F-FPEB PET in humans. J Nucl Med 51(Supplement 2):215.
    • (2010) J Nucl Med , vol.51 , Issue.SUPPL. 2 , pp. 215
    • Barret, O.1
  • 41
    • 34047226403 scopus 로고    scopus 로고
    • Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688
    • Ametamey SM, et al. (2007) Human PET studies of metabotropic glutamate receptor subtype 5 with 11C-ABP688. J Nucl Med 48(2):247-252.
    • (2007) J Nucl Med , vol.48 , Issue.2 , pp. 247-252
    • Ametamey, S.M.1
  • 42
    • 0037203324 scopus 로고    scopus 로고
    • Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum
    • Malherbe P, et al. (2002) Identification and characterization of a novel splice variant of the metabotropic glutamate receptor 5 gene in human hippocampus and cerebellum. Brain Res Mol Brain Res 109(1-2):168-178.
    • (2002) Brain Res Mol Brain Res , vol.109 , Issue.1-2 , pp. 168-178
    • Malherbe, P.1
  • 43
    • 0029144222 scopus 로고
    • Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5
    • Daggett LP, et al. (1995) Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5. Neuropharmacology 34(8):871-886.
    • (1995) Neuropharmacology , vol.34 , Issue.8 , pp. 871-886
    • Daggett, L.P.1
  • 44
    • 0033576766 scopus 로고    scopus 로고
    • Expression of metabotropic glutamate receptor subtype mRNA (mGluR1-8) in human cerebellum
    • Berthele A, et al. (1999) Expression of metabotropic glutamate receptor subtype mRNA (mGluR1-8) in human cerebellum. Neuroreport 10(18):3861-3867.
    • (1999) Neuroreport , vol.10 , Issue.18 , pp. 3861-3867
    • Berthele, A.1
  • 45
    • 35848943027 scopus 로고    scopus 로고
    • Species differences in mGluR5 binding sites in mammalian central nervous system determined using in vitro binding with [18F]F-PEB
    • Patel S, et al. (2007) Species differences in mGluR5 binding sites in mammalian central nervous system determined using in vitro binding with [18F]F-PEB. Nucl Med Biol 34(8):1009-1017.
    • (2007) Nucl Med Biol , vol.34 , Issue.8 , pp. 1009-1017
    • Patel, S.1
  • 46
    • 84861096326 scopus 로고    scopus 로고
    • The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine
    • Kupchik YM, et al. (2012) The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine. Biol Psychiatry 71(11):978-986.
    • (2012) Biol Psychiatry , vol.71 , Issue.11 , pp. 978-986
    • Kupchik, Y.M.1
  • 47
    • 77956465568 scopus 로고    scopus 로고
    • Neurobiological mechanisms involved in nicotine dependence and reward: Participation of the endogenous opioid system
    • Berrendero F, Robledo P, Trigo JM, Martín-García E, Maldonado R (2010) Neurobiological mechanisms involved in nicotine dependence and reward: Participation of the endogenous opioid system. Neurosci Biobehav Rev 35(2):220-231.
    • (2010) Neurosci Biobehav Rev , vol.35 , Issue.2 , pp. 220-231
    • Berrendero, F.1    Robledo, P.2    Trigo, J.M.3    Martín-García, E.4    Maldonado, R.5
  • 50
    • 0024338367 scopus 로고
    • Measuring nicotine dependence: A review of the Fagerstrom Tolerance Questionnaire
    • Fagerstrom KO, Schneider NG (1989) Measuring nicotine dependence: A review of the Fagerstrom Tolerance Questionnaire. J Behav Med 12(2):159-182.
    • (1989) J Behav Med , vol.12 , Issue.2 , pp. 159-182
    • Fagerstrom, K.O.1    Schneider, N.G.2
  • 51
    • 0024245652 scopus 로고
    • An inventory for measuring clinical anxiety: Psychometric properties
    • Beck AT, Epstein N, Brown G, Steer RA (1988) An inventory for measuring clinical anxiety: Psychometric properties. J Consult Clin Psychol 56(6):893-897.
    • (1988) J Consult Clin Psychol , vol.56 , Issue.6 , pp. 893-897
    • Beck, A.T.1    Epstein, N.2    Brown, G.3    Steer, R.A.4
  • 53
    • 0027395478 scopus 로고
    • Comparison of bolus and infusion methods for receptor quantitation: Application to [18F]cyclofoxy and positron emission tomography
    • Carson RE, et al. (1993) Comparison of bolus and infusion methods for receptor quantitation: Application to [18F]cyclofoxy and positron emission tomography. J Cereb Blood Flow Metab 13(1):24-42.
    • (1993) J Cereb Blood Flow Metab , vol.13 , Issue.1 , pp. 24-42
    • Carson, R.E.1
  • 54
    • 77956986927 scopus 로고    scopus 로고
    • Evaluation of a bolus/infusion protocol for 11C-ABP688, a PET tracer for mGluR5
    • Burger C, et al. (2010) Evaluation of a bolus/infusion protocol for 11C-ABP688, a PET tracer for mGluR5. Nucl Med Biol 37(7):845-851.
    • (2010) Nucl Med Biol , vol.37 , Issue.7 , pp. 845-851
    • Burger, C.1
  • 55
    • 79960504561 scopus 로고
    • Strategies for the study of the opaite receptor in brain: Application to the opiate antagonist cyclofoxy
    • Blasberg RG, et al. (1989) Strategies for the study of the opaite receptor in brain: Application to the opiate antagonist cyclofoxy. J Cereb Blood Flow Metab 9:S732.
    • (1989) J Cereb Blood Flow Metab , vol.9
    • Blasberg, R.G.1
  • 56
    • 34447343093 scopus 로고    scopus 로고
    • Evaluation of the metabotropic glutamate receptor subtype 5 using PET and 11C-ABP688: Assessment of methods
    • Treyer V, et al. (2007) Evaluation of the metabotropic glutamate receptor subtype 5 using PET and 11C-ABP688: Assessment of methods. J Nucl Med 48(7):1207-1215.
    • (2007) J Nucl Med , vol.48 , Issue.7 , pp. 1207-1215
    • Treyer, V.1


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