-
1
-
-
0027363029
-
Plasma and platelet excitatory amino acids in psychiatric disorders
-
Altamura CA, Mauri MC, Ferrara A, Moro AR, D'Andrea G, Zamberlan F (1993) Plasma and platelet excitatory amino acids in psychiatric disorders. Am J Psychiatry 150:1731-1733
-
(1993)
Am J Psychiatry
, vol.150
, pp. 1731-1733
-
-
Altamura, C.A.1
Mauri, M.C.2
Ferrara, A.3
Moro, A.R.4
D'Andrea, G.5
Zamberlan, F.6
-
2
-
-
33751190762
-
Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
-
Belozertseva IV, Kos T, Popik P, Danysz W, Bespalov AY (2007) Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests. Eur Neuropsychopharmacol 17:172-179
-
(2007)
Eur Neuropsychopharmacol
, vol.17
, pp. 172-179
-
-
Belozertseva, I.V.1
Kos, T.2
Popik, P.3
Danysz, W.4
Bespalov, A.Y.5
-
3
-
-
16344378248
-
Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus
-
Bonanno G, Giambelli R, Raiteri L, Tiraboschi E, Zappettini S, Musazzi L, Raiteri M, Racagni G, Popoli M (2005) Chronic antidepressants reduce depolarization-evoked glutamate release and protein interactions favoring formation of SNARE complex in hippocampus. J Neurosci 25:3270-3279
-
(2005)
J Neurosci
, vol.25
, pp. 3270-3279
-
-
Bonanno, G.1
Giambelli, R.2
Raiteri, L.3
Tiraboschi, E.4
Zappettini, S.5
Musazzi, L.6
Raiteri, M.7
Racagni, G.8
Popoli, M.9
-
4
-
-
0033844601
-
Regulation of neurotransmitter release by metabotropic glutamate receptors
-
Cartmell J, Schoepp DD (2000) Regulation of neurotransmitter release by metabotropic glutamate receptors. J Neurochem 75:889-907
-
(2000)
Neurochem
, vol.75
, pp. 889-907
-
-
Cartmell, J.1
Schoepp, D.D.2
-
5
-
-
10744233803
-
MGS0039: A potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity
-
Chaki S, Yoshikawa R, Hirota S, Shimazaki T, Maeda M, Kawashima N, Yoshimizu T, Yasuhara A, Sakagami K, Okuyama S, Nakanishi S, Nakazato A (2004) MGS0039: a potent and selective group II metabotropic glutamate receptor antagonist with antidepressant-like activity. Neuropharmacology 46:457-467
-
(2004)
Neuropharmacology
, vol.46
, pp. 457-467
-
-
Chaki, S.1
Yoshikawa, R.2
Hirota, S.3
Shimazaki, T.4
Maeda, M.5
Kawashima, N.6
Yoshimizu, T.7
Yasuhara, A.8
Sakagami, K.9
Okuyama, S.10
Nakanishi, S.11
Nakazato, A.12
-
6
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
Conn PJ, Pin JP (1997) Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol 37:205-237
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.P.2
-
7
-
-
0038391169
-
Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7
-
Cryan JF, Kelly PH, Neijt HC, Sansig G, Flor PJ, Van Der Putten H (2003) Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. Eur J Neurosci 17:2409-2417
-
(2003)
Eur J Neurosci
, vol.17
, pp. 2409-2417
-
-
Cryan, J.F.1
Kelly, P.H.2
Neijt, H.C.3
Sansig, G.4
Flor, P.J.5
Van Der Putten, H.6
-
8
-
-
34848909698
-
mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity
-
(in press)
-
Fendt M, Schmid S, Thakker DR, Jacobson LH, Yamamoto R, Mitsukawa K, Maier R, Natt F, Hüsken D, Kelly PH, McAllister KH, Hoyer D, van der Putten H, Cryan JF, Flor PJ (2007) mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity. Mol Psychiatry (in press)
-
(2007)
Mol Psychiatry
-
-
Fendt, M.1
Schmid, S.2
Thakker, D.R.3
Jacobson, L.H.4
Yamamoto, R.5
Mitsukawa, K.6
Maier, R.7
Natt, F.8
Hüsken, D.9
Kelly, P.H.10
McAllister, K.H.11
Hoyer, D.12
Van Der Putten, H.13
Cryan, J.F.14
Flor, P.J.15
-
9
-
-
0034502510
-
Effect of acute and chronic administration of citalopram on glutamate and aspartate release in the rat prefrontal cortex
-
Golembiowska K, Dziubina A (2000) Effect of acute and chronic administration of citalopram on glutamate and aspartate release in the rat prefrontal cortex. Pol J Pharmacol 52:441-448
-
(2000)
Pol J Pharmacol
, vol.52
, pp. 441-448
-
-
Golembiowska, K.1
Dziubina, A.2
-
10
-
-
0242391960
-
Abnormal behavioral phenotypes of serotonin transporter knockout mice: Parallels with human anxiety and depression
-
Holmes A, Murphy DL, Crawley JN (2003) Abnormal behavioral phenotypes of serotonin transporter knockout mice: parallels with human anxiety and depression. Biol Psychiatry 54:953-959
-
(2003)
Biol Psychiatry
, vol.54
, pp. 953-959
-
-
Holmes, A.1
Murphy, D.L.2
Crawley, J.N.3
-
11
-
-
0032513558
-
Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: A light and electron microscopic study
-
Kinoshita A, Shigemoto R, Ohishi H, van der Putten H, Mizuno N (1998) Immunohistochemical localization of metabotropic glutamate receptors, mGluR7a and mGluR7b, in the central nervous system of the adult rat and mouse: a light and electron microscopic study. J Comp Neurol 393:332-352
-
(1998)
J Comp Neurol
, vol.393
, pp. 332-352
-
-
Kinoshita, A.1
Shigemoto, R.2
Ohishi, H.3
Van Der Putten, H.4
Mizuno, N.5
-
12
-
-
33846666910
-
Combined administration of PHCCC, a positive allosteric modulator of mGluR4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats
-
Klak K, Palucha A, Branski P, Sowa M, Pilc A (2007) Combined administration of PHCCC, a positive allosteric modulator of mGluR4 receptors and ACPT-I, mGlu III receptor agonist evokes antidepressant-like effects in rats. Amino Acids 32:169-172
-
(2007)
Amino Acids
, vol.32
, pp. 169-172
-
-
Klak, K.1
Palucha, A.2
Branski, P.3
Sowa, M.4
Pilc, A.5
-
13
-
-
0242456044
-
Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice
-
Lira A, Zhou M, Castanon N, Ansorge MS, Gordon JA, Francis JH, Bradley-Moore M, Lira J, Underwood MD, Arango V, Kung HF, Hofer MA, Hen R, Gingrich JA (2003) Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biol Psychiatry 54:960-971
-
(2003)
Biol Psychiatry
, vol.54
, pp. 960-971
-
-
Lira, A.1
Zhou, M.2
Castanon, N.3
Ansorge, M.S.4
Gordon, J.A.5
Francis, J.H.6
Bradley-Moore, M.7
Lira, J.8
Underwood, M.D.9
Arango, V.10
Kung, H.F.11
Hofer, M.A.12
Hen, R.13
Gingrich, J.A.14
-
14
-
-
29444435620
-
A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo
-
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ (2005) A selective metabotropic glutamate receptor 7 agonist: activation of receptor signaling via an allosteric site modulates stress parameters in vivo. Proc Natl Acad Sci U S A 102:18712-18717
-
(2005)
Proc Natl Acad Sci U S a
, vol.102
, pp. 18712-18717
-
-
Mitsukawa, K.1
Yamamoto, R.2
Ofner, S.3
Nozulak, J.4
Pescott, O.5
Lukic, S.6
Stoehr, N.7
Mombereau, C.8
Kuhn, R.9
McAllister, K.H.10
Van Der Putten, H.11
Cryan, J.F.12
Flor, P.J.13
-
15
-
-
33745675486
-
Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: Implications for stress-related psychiatric disorders
-
Mitsukawa K, Mombereau C, Lötscher E, Uzunov DP, van der Putten H, Flor PJ, Cryan JF (2006) Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders. Neuropsychopharmacology 31:1112-1122
-
(2006)
Neuropsychopharmacology
, vol.31
, pp. 1112-1122
-
-
Mitsukawa, K.1
Mombereau, C.2
Lötscher, E.3
Uzunov, D.P.4
Van Der Putten, H.5
Flor, P.J.6
Cryan, J.F.7
-
16
-
-
33845213369
-
Are compounds acting at metabotropic glutamate receptors the answer to treating depression?
-
Palucha A (2006) Are compounds acting at metabotropic glutamate receptors the answer to treating depression? Expert Opin Investig Drugs 15:1545-1553
-
(2006)
Expert Opin Investig Drugs
, vol.15
, pp. 1545-1553
-
-
Palucha, A.1
-
17
-
-
34347241277
-
Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs
-
Palucha A, Pilc A (2007) Metabotropic glutamate receptor ligands as possible anxiolytic and antidepressant drugs. Pharmacol Ther 115:116-147
-
(2007)
Pharmacol Ther
, vol.115
, pp. 116-147
-
-
Palucha, A.1
Pilc, A.2
-
18
-
-
0346219343
-
Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats
-
Palucha A, Tatarczynska E, Branski P, Szewczyk B, Wieronska JM, Klak K, Chojnacka Wojcik E, Nowak G, Pilc A (2004) Group III mGlu receptor agonists produce anxiolytic- and antidepressant-like effects after central administration in rats. Neuropharmacology 46:151-159
-
(2004)
Neuropharmacology
, vol.46
, pp. 151-159
-
-
Palucha, A.1
Tatarczynska, E.2
Branski, P.3
Szewczyk, B.4
Wieronska, J.M.5
Klak, K.6
Chojnacka Wojcik, E.7
Nowak, G.8
Pilc, A.9
-
19
-
-
23944453080
-
Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist
-
Palucha A, Branski P, Szewczyk B, Wieronska JM, Klak K, Pilc A (2005) Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pharmacol Biochem Behav 81:901-906
-
(2005)
Pharmacol Biochem Behav
, vol.81
, pp. 901-906
-
-
Palucha, A.1
Branski, P.2
Szewczyk, B.3
Wieronska, J.M.4
Klak, K.5
Pilc, A.6
-
20
-
-
0346461630
-
Glutamate and depression: Clinical and preclinical studies
-
Paul IA, Skolnick P (2002) Glutamate and depression: clinical and preclinical studies. Ann N Y Acad Sci 1003:250-272
-
(2002)
Ann N Y Acad Sci
, vol.1003
, pp. 250-272
-
-
Paul, I.A.1
Skolnick, P.2
-
21
-
-
16844380129
-
MGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition
-
Pelkey KA, Lavezzari G, Racca C, Roche KW, McBain CJ (2005) mGluR7 is a metaplastic switch controlling bidirectional plasticity of feedforward inhibition. Neuron 46:89-102
-
(2005)
Neuron
, vol.46
, pp. 89-102
-
-
Pelkey, K.A.1
Lavezzari, G.2
Racca, C.3
Roche, K.W.4
McBain, C.J.5
-
22
-
-
33845871976
-
MGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082
-
Pelkey KA, Yuan X, Lavezzari G, Roche KW, McBain CJ (2006) mGluR7 undergoes rapid internalization in response to activation by the allosteric agonist AMN082. Neuropharmacology 52:108-117
-
(2006)
Neuropharmacology
, vol.52
, pp. 108-117
-
-
Pelkey, K.A.1
Yuan, X.2
Lavezzari, G.3
Roche, K.W.4
McBain, C.J.5
-
23
-
-
0036669731
-
Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats
-
Pilc A, Klodzinska A, Branski P, Nowak G, Palucha A, Szewczyk B, Tatarczynska E, Chojnacka-Wojcik E, Wieronska JM (2002) Multiple MPEP administrations evoke anxiolytic- and antidepressant-like effects in rats. Neuropharmacology 43:181-187
-
(2002)
Neuropharmacology
, vol.43
, pp. 181-187
-
-
Pilc, A.1
Klodzinska, A.2
Branski, P.3
Nowak, G.4
Palucha, A.5
Szewczyk, B.6
Tatarczynska, E.7
Chojnacka-Wojcik, E.8
Wieronska, J.M.9
-
24
-
-
0017651126
-
Behavioral despair in mice: A primary screening test for antidepressants
-
Porsolt RD, Bertin A, Jalfre M (1977) Behavioral despair in mice: a primary screening test for antidepressants. Arch Int Pharmacodyn Ther 229:327-336
-
(1977)
Arch Int Pharmacodyn Ther
, vol.229
, pp. 327-336
-
-
Porsolt, R.D.1
Bertin, A.2
Jalfre, M.3
-
25
-
-
0025636351
-
Effects of antidepressive agents on glutamatergic autoregulatory presynaptic mechanism in the rat cerebral cortex
-
Prikhozhan AV, Kovalev GI, Raevskii KS (1990) Effects of antidepressive agents on glutamatergic autoregulatory presynaptic mechanism in the rat cerebral cortex. Bull Exp Biol Med 110:624-626
-
(1990)
Bull Exp Biol Med
, vol.110
, pp. 624-626
-
-
Prikhozhan, A.V.1
Kovalev, G.I.2
Raevskii, K.S.3
-
26
-
-
33746871416
-
Can siRNA technology provide the tools for gene therapy of the future?
-
Racz Z, Hamar P (2006) Can siRNA technology provide the tools for gene therapy of the future? Curr Med Chem 13:2299-2307
-
(2006)
Curr Med Chem
, vol.13
, pp. 2299-2307
-
-
Racz, Z.1
Hamar, P.2
-
27
-
-
26444616159
-
Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators
-
Ritzen A, Mathiesen JM, Thomsen C (2005) Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators. Basic Clin Pharmacol Toxicol 97:202-213
-
(2005)
Basic Clin Pharmacol Toxicol
, vol.97
, pp. 202-213
-
-
Ritzen, A.1
Mathiesen, J.M.2
Thomsen, C.3
-
28
-
-
3042696715
-
Specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression
-
Sanacora G, Gueorguieva R, Epperson CN, Wu YT, Appel M (2004) Specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression. Arch Gen Psychiatry 61:705-713
-
(2004)
Arch Gen Psychiatry
, vol.61
, pp. 705-713
-
-
Sanacora, G.1
Gueorguieva, R.2
Epperson, C.N.3
Wu, Y.T.4
Appel, M.5
-
29
-
-
0035890279
-
Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7
-
Sansig G, Bushell TJ, Clarke VRJ, Rozov A, Burnashev N, Portet C, Gasparini F, Schmutz M, Klebs K, Shigemoto R, Flor PJ, Kuhn R, Knoepfel T, Schroeder M, Hampson DR, Collett VJ, Zhang C, Duvoisin RM, Collingridge GL, van der Putten H (2001) Increased seizure susceptibility in mice lacking metabotropic glutamate receptor 7. J Neurosci 21:8734-8745
-
(2001)
J Neurosci
, vol.21
, pp. 8734-8745
-
-
Sansig, G.1
Bushell, T.J.2
Clarke, V.R.J.3
Rozov, A.4
Burnashev, N.5
Portet, C.6
Gasparini, F.7
Schmutz, M.8
Klebs, K.9
Shigemoto, R.10
Flor, P.J.11
Kuhn, R.12
Knoepfel, T.13
Schroeder, M.14
Hampson, D.R.15
Collett, V.J.16
Zhang, C.17
Duvoisin, R.M.18
Collingridge, G.L.19
Van Der Putten, H.20
more..
-
30
-
-
0034811597
-
Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system
-
Schoepp DD (2001) Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system. J Pharmacol Exp Ther 299:12-20
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 12-20
-
-
Schoepp, D.D.1
-
31
-
-
33846291863
-
Anxiolytic-like effects of group III mGlu receptor agonist ACPT-I administered intrahippocampally involve GABA-A signaling
-
Stachowicz K, Chojnacka-Wojcik E, Klak K, Pilc A (2006) Anxiolytic-like effects of group III mGlu receptor agonist ACPT-I administered intrahippocampally involve GABA-A signaling. Pharmacol Rep 58:820-826
-
(2006)
Pharmacol Rep
, vol.58
, pp. 820-826
-
-
Stachowicz, K.1
Chojnacka-Wojcik, E.2
Klak, K.3
Pilc, A.4
-
32
-
-
33846266524
-
Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent
-
Stachowicz K, Chojnacka-Wojcik E, Klak K, Pilc A (2007) Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent. Neuropharmacology 52:306-312
-
(2007)
Neuropharmacology
, vol.52
, pp. 306-312
-
-
Stachowicz, K.1
Chojnacka-Wojcik, E.2
Klak, K.3
Pilc, A.4
-
34
-
-
0035069188
-
Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist
-
Tatarczynska E, Klodzinska A, Chojnacka-Wojcik E, Palucha A, Gasparini F, Kuhn R, Pilc A (2001) Potential anxiolytic- and antidepressant-like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist. Br J Pharmacol 132:1423-1430
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1423-1430
-
-
Tatarczynska, E.1
Klodzinska, A.2
Chojnacka-Wojcik, E.3
Palucha, A.4
Gasparini, F.5
Kuhn, R.6
Pilc, A.7
-
35
-
-
0036971043
-
Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4-tricarboxylic acid (ACPT-I) in rats
-
Tatarczynska E, Palucha A, Szewczyk B, Chojnacka-Wojcik E, Wieronska JM, Pilc A (2002) Anxiolytic- and antidepressant-like effects of group III metabotropic glutamate agonist (1S,3R,4S)-1-aminocyclopentane-1,3,4- tricarboxylic acid (ACPT-I) in rats. Pol J Pharmacol 54:707-710
-
(2002)
Pol J Pharmacol
, vol.54
, pp. 707-710
-
-
Tatarczynska, E.1
Palucha, A.2
Szewczyk, B.3
Chojnacka-Wojcik, E.4
Wieronska, J.M.5
Pilc, A.6
-
36
-
-
32844459722
-
MGluR7 plays a key role in the modulation of anxiety behavior: Evidence from mGluR7-knockout mice and siRNA-induced knockdown in the adult mouse brain
-
Thakker DR, Hoyer D, Schmutz M, Maier R, Natt F, Husken D, Sansig G, van der Putten H, Flor PJ, Cryan JF (2005a) mGluR7 plays a key role in the modulation of anxiety behavior: evidence from mGluR7-knockout mice and siRNA-induced knockdown in the adult mouse brain. Neuropharmacology 49:275 (abstracts)
-
(2005)
Neuropharmacology
, vol.49
, pp. 275
-
-
Thakker, D.R.1
Hoyer, D.2
Schmutz, M.3
Maier, R.4
Natt, F.5
Husken, D.6
Sansig, G.7
Van Der Putten, H.8
Flor, P.J.9
Cryan, J.F.10
-
37
-
-
23744466180
-
SiRNA-mediated knockdown of the serotonin transporter in the adult mouse brain
-
Thakker DR, Natt F, Husken D, van der Putten H, Maier R, Hoyer D, Cryan JF (2005b) siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. Mol Psychiatry 10:782-789
-
(2005)
Mol Psychiatry
, vol.10
, pp. 782-789
-
-
Thakker, D.R.1
Natt, F.2
Husken, D.3
Van Der Putten, H.4
Maier, R.5
Hoyer, D.6
Cryan, J.F.7
-
38
-
-
0036386865
-
Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats
-
Wieronska JM, Szewczyk B, Branski P, Palucha A, Pilc A (2002) Antidepressant-like effect of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist in the olfactory bulbectomized rats. Amino Acids 23:213-216
-
(2002)
Amino Acids
, vol.23
, pp. 213-216
-
-
Wieronska, J.M.1
Szewczyk, B.2
Branski, P.3
Palucha, A.4
Pilc, A.5
-
39
-
-
33744957683
-
An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats
-
Yoshimizu T, Shimazaki T, Ito A, Chaki S (2006) An mGluR2/3 antagonist, MGS0039, exerts antidepressant and anxiolytic effects in behavioral models in rats. Psychopharmacology (Berl) 186:587-593
-
(2006)
Psychopharmacology (Berl)
, vol.186
, pp. 587-593
-
-
Yoshimizu, T.1
Shimazaki, T.2
Ito, A.3
Chaki, S.4
|