Antagonism at metabotropic glutamate 5 receptors inhibits nicotine- and cocaine-taking behaviours and prevents nicotine-triggered relapse to nicotine-seeking

European Journal of Pharmacology

Volumn 499, Issue 1-2, 2004, Pages 121-133

  Tessari, Michela ^a,b   Pilla, Maria ^a   Andreoli, Michela ^a   Hutcheson, Daniel M ^a   Heidbreder, Christian A ^a  

^a GSK   (Italy)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Cocaine; Food; Metabotropic glutamate receptors; MPEP; Nicotine; Self administration

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; COCAINE; GLUTAMATE RECEPTOR 5; GLUTAMATE RECEPTOR ANTAGONIST; NICOTINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG DEPENDENCE; DRUG EFFECT; DRUG SELF ADMINISTRATION; FOOD INTAKE; HYPOTHESIS; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT; RECURRENT DISEASE; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ANIMAL; COCAINE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; INJECTIONS, INTRAVENOUS; MALE; MOTOR ACTIVITY; NICOTINE; PSYCHOMOTOR PERFORMANCE; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECURRENCE; SELF ADMINISTRATION; SUBSTANCE-RELATED DISORDERS;

EID: 19244387486     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.07.056     Document Type: Article

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