Metabotropic glutamate receptors modulate serotonin release in the rat periaqueductal gray matter

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 358, Issue 4, 1998, Pages 411-417

  Maione, Sabatino ^a   Palazzo, Enza ^a   De Novellis, Vito ^a   Stella, Luigi ^a   Leyva, Juan ^a   Rossi, Francesco ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

5 HT; Metabotropic glutamate receptors; NMDA glutamate receptors; PAG matter

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 (CARBOXYCYCLOPROPYL)GLYCINE; 3,5 DIHYDROPHENYLGLYCINE; ALPHA ETHYLGLUTAMIC ACID; ALPHA METHYLSERINE O PHOSPHATE; BICUCULLINE; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; GLUTAMIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NALOXONE; PHOSPHOSERINE; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTERNEURON; MALE; MICRODIALYSIS; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM;

ANIMALS; CYCLOLEUCINE; MALE; MICRODIALYSIS; PERIAQUEDUCTAL GRAY; PHOSPHOSERINE; RATS; RATS, WISTAR; RECEPTORS, GABA; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RECEPTORS, OPIOID; SEROTONIN;

EID: 0031658795     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00005272     Document Type: Article

References (38)

1. Allen DL, Johnson AE, Tempel A, Zukin RS, Luine VN, McEwen BS (1993) Serotonergic lesions decrease μ and δ-opiate receptor binding in discrete areas of the hypothalamus and in the midbrain central gray. Brain Res 625:269-275
2. A receptors in the midbrain central grey mediate the anti-aversive action of GABA. Eur J Pharmacol 135:225-229
3. Azmitia EC (1978) The serotonergic producing neurons of the midbrain median and dorsal raphe nuclei. In L.L. Iversen, S.D. Iversen and Snyder S. H. (eds.) Handbook of Psychopharmacology, Vol. 9: Chemical Pathways in the Brain, Plenum, New York, p. 233-314
4. Bandler R, Depaulis A (i 988) Elicitation of intraspecific defence reactions in the rat from the midbrain periaqueductal grey by microinjection of kainic acid, without neurotoxic effects. Neurosci Lett 88:291-296
5. 3H]GABA. Neuroscience 34:163-176
6. Beckett SRG, Lawrence AJ, Marsden CA and Marshal PW (1992) Attenuation of chemically induced defence response hy 5-HT, receptor agonists administered into the periaqueductal grey. Psychopharmacology 108:110-114
7. Becquet D, Faudon M and Hery F (1990) In vivo evidence for an inhibitory glutamatergic control of serotonin release in the cat caudate nucleus: involvement of GABA neurons. Brain Res 519:82-88
8. Catania MV, De Socarraz H, Penney JB, Young AB (1994) Metabotropic glutamate receptors heterogeneity in rat brain. Mol Pharmacol 45:626-636
9. Constantino G, Pellicciari R (1996) Homology modeling of metabotropic glutamate receptors (mGluRs). Structural motifs affecting binding models and pharmacological profile of mGluR1 agonists and competitive antagonists. J Med Chem 39:3998-4006
10. Deakin JWF, Graeff FG (1991) 5-HT and mechanism of defence. J Psychopharmacology 5:305-315
11. Doherty AJ, Palmer MJ, Henley JM, Collingridge GL, Jane DE (1997) (RS)-2-Chloro-5-Hydroxyphenylglycine (CHPG) activates mGluR5, but not mGluR1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus. Neuropharmacology 36:265-267
12. East SJ, Hill MP, Brotchie JM (1995) Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes. Eur J Pharmacol 277:117-121
13. Graeff FG (1990) Brain defense systems and anxiety. In: Roth M, Burrows GD, Noyes R (eds) Handbook of Anxiety. The Neurobiology of Anxiety, Elsevier, Amsterdam, pp 307-354
14. Guimar FS, Carobrez AP, de Aguiar JC, Graeff FG (1991 ) Anxiolitic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey. Psychopharmacology 103:91-96
15. Hutson PH, Sarna GS, Kantamaneni BD, Curzon G (1985) Monitoring the effect of a tryptophan load on brain indole metabolism in freely moving rats by simultaneus cerebrospinal fluid sampling and brain dialysis. J Neurochem 44:1266-1273
16. Jane DE, Thomas NK, Tse H-W, Watkins JC (1996) Potent antagonist at the L-AP4 and 1S.3R-ACPD sensitive presynaptic metabotropic glutamate receptors in the neonatal rat spinal cord. Neuropharmacology 35:1029-1035
17. Johnson MD, Crowley WR (1984) Effects of opiate antagonists on serotonin turnover and on luteinizing hormone and prolactin secretion in estrogen-or mophine-treated rats. Neuroendocrinology 38:322-327
18. Jolas T, Aghajanian GK (1997) Opioids suppress spontaneous and NMDA-induced inhibitory post-synaptic currents in the dorsal raphe nucleus of the rat in vitro. Brain Res 755:229-245
19. 3H]-aspartate output in rat striatum. Br J Pharmacol 110:1407-1412
20. Maione S, Leyva J, Pallotta M, Berrino L, De Novellis V, Rossi F (1995) Involvement of opioids receptors in N-methyl-D-aspartate-indiced arterial hypertension in periaqueductal gray matter. Naunyn-Schmiedeberg's Arch Pharmacol 351:87-92
21. Maione S., Rossi F., Biggs C.S., Flower L.J., Whitton P.S (1997) AMPA receptors modulate extracellular 5-hydroxytriptamine concentration and metabolism in rat striatum in vivo. Neurochem Int 30:299-304
22. Mammounas LA, Mullen CA, O'Hearn E, Molliver ME (1991) Dual serotonergic projections to forebrain in the rat: morphologically distinct 5-HT axon terminals exhibit differential vulnerability to neurotoxic amphetamine derivatives. J Comp Neurol 314:558-586
23. Mayer ML, Westbrook GL (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog Neurobiol 28:197-276
24. McCormick DA, von Krosigk M (1992) Corticothalamic activation modulates thalamic firing though glutamate metabotropic receptors. Proc Natl Acad Sci USA 89:2774-2778
25. Moroni F, Lombardi G, Thomsen C, Leonardi P, Attucci S, Peruginelli F, Albani Torregrossa S, Pellegrini-Giampietro DE, Luneia R, Pellicciari R (1997) Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent niGluR1 antagonist. J Pharmacol Exp Ther 281:721-729
26. Nakanishi S (1992) Molecular diversity of glutamate receptors and implication for brain function. Science 258:597-603
27. Paxinos G, Watson C (1986) The Rat Brain in Stereotaxic Coordinates. Academic Press, London
28. Pin JP, Duvoisin R (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34:1-26
29. Roberts PJ (1995) Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists, an uptate. Neuropharmacology 34:813-819
30. Schütz MTB, de Aguiar JC, Graeff FG (1985) Anti-aversive role of serotonin on the dorsal periaqueductal grey matter. Psychopharmacology 85:340-345
31. Sekiyama N, Hayashi Y, Nakanishi S, Jane DE, Tse H-W, Birse EF, Watkins JC (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br J Pharmacol 117:1493-1503
32. Shigemoto R, Kulik A, Roberts JDB, Ohishi H, Nusser Z, Kaneko T, Somogyi P (1996) Target-cell-specific concentration of a metabotropic glutamate receptor in the presynaptic active zone. Nature 381:523-525
33. Tao R, Auerbach SB (1996) Differential effect of NMDA receptors to on extracellular serotonin in rat midbrain raphe and forebrain sites. J Neurochem 66:1067-1075
34. Thomas NK, Jane DE, Tse H-W, Watkins JC (1996) α-Methyl derivatives of serine-O-phosphate as novel, selective competitive metabotropic glutamate receptor antagonists. Neuropharmacology 35:637-642
35. Watkins JC, Collingridge G (1994) Phenylglyine derivatives as antagonists of metabotropic glutamate receptors. Trends Pharmac Sci 15:333-342
36. Whitton PS, Maione S, Biggs CS, Fowler LJ (1994) Tonic desensitization of hippocampal AMPA receptors regulates 5-HT release in vivo. Neuroscience 63:945-948
37. Wigmore MA, Lacey MG (1998) Metabotropic glutamate receptors depress glutamate-mediated synaptic input to rat midbrain dopamine neurons in vitro Br J Pharmacol 123:667-674
38. Zhang SP, Bandler R, Carrive P (1990) Flight and immobility evoked by excitatory amino acid microinjection within distinct parts of the subtentorial midbrain periaqueductal grey of the cat. Brain Res 520:73-82