The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase Cε-dependent mechanism

Molecular Pharmacology

Volumn 67, Issue 2, 2005, Pages 349-355

  Olive, M Foster ^a   Mcgeehan, Andrew J ^a   Kinder, Jennifer R ^a   McMahon, Thomas ^a   Hodge, Clyde W ^b   Janak, Patricia H ^a   Messing, Robert O ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 5 HYDROXYPHENYLGLYCINE; 6 METHYL 2 (PHENYLETHYNYL)PYRIDINE; ALCOHOL; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; RADIOLIGAND; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENETIC VARIABILITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ALCOHOL DRINKING; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MICE; MICE, INBRED C57BL; PROTEIN KINASE C; PROTEIN KINASE C-EPSILON; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 13444291828     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.003319     Document Type: Article

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