Enhancement of NMDA responses by group I metabotropic glutamate receptor activation in striatal neurones

British Journal of Pharmacology

Volumn 120, Issue 6, 1997, Pages 1007-1014

  Pisani, Antonio ^a   Calabresi, Paolo ^a   Centonze, Diego ^a   Bernardi, Giorgio ^a,b  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

Author keywords

Electrophysiology; Excitotoxicity; Metabotropic glutamate receptors (mGluRs); N methyl D aspartate (NMDA); Neurodegenerative disorders; Phenylglycines; Plasticity; Striatum

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 (CARBOXYCYCLOPROPYL)GLYCINE; 3,5 DIHYDROXYPHENYLGLYCINE; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; AMPA RECEPTOR; CALPHOSTIN C; CYCLOLEUCINE; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHORBOL DIACETATE; PHOSPHOSERINE; PROTEIN KINASE C; STAUROSPORINE;

ANIMAL CELL; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORPUS STRIATUM; ELECTROPHYSIOLOGY; MALE; MEMBRANE DEPOLARIZATION; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; CYCLOLEUCINE; EXCITATORY AMINO ACID AGENTS; GLYCINE; MALE; N-METHYLASPARTATE; NEOSTRIATUM; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN KINASE C; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; RECEPTORS, N-METHYL-D-ASPARTATE; RESORCINOLS;

EID: 0030898586     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0700999     Document Type: Article

References (60)

1. ALBIN, R.L. & GREENAMYRE, J.T. (1992). Alternative excitotoxic hypothesis. Neurology, 42, 733-738.
2. ALEPPO, G., PISANI, A., COPANI, A., BRUNO, V., ARONICA, E., D'AGATA, V., CANONICO, P.L. & NICOLETTI, F. (1992). Metabotropic glutamate receptors and neuronal toxicity. In Neurobiology of Essential Fatty Acids, ed. Bazan, N.G., Horrock, L. & Toffano, G. pp. 137-145, New York: Plenum Press.
3. AMBROSINI, A., BRESCIANI, L., FRACCHIA, S., BRUNELLO, N. & RACAGNI, G. (1995). Metabotropic glutamate receptors negatively coupled to adenylate cyclase inhibit N-methyl-D-aspartate activity and prevent neurotoxicity in mesencephalic neurons in vitro. Mol. Pharmacol., 47, 1057-1064.
4. ANIKSZTEJN, L., OTANI, S. & BEN-ARI, Y. (1992). Quisqualate metabotropic receptors modulate NMDA currents and facilitate induction of long-term potentiation through protein kinase C. Eur. J. Neurosci., 4, 500-505.
5. BEAL, F.M. (1992). Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? Ann. Neurol., 31, 119-130.
6. BEAL, M.F., FINN, S.F. & BROUILLET, E. (1993). Evidence for the involvement of metabotropic glutamate receptors in striatal excitotoxic lesions in vivo. Neurodegeneration, 2, 81-91.
7. BEAL, M.F., KOWALL, N.W., ELLISON, D.W., MAZUREK, M.F., SWARTZ, K.J. & MARTIN, J.B. (1986). Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid. Nature, 321, 168-171.
8. BEAR, M.F. & MALENKA, R.C. (1994). Synaptic plasticity: LTP and LTD. Curr. Op. Neurobiol., 4, 389-399.
9. BEN-ARI, Y., ANIKSZTEJN, L. & BREGESTOVSKI, P. (1992). Protein kinase C modulation of NMDA currents: an important link for LTP induction. Trends Neurosci., 15, 333-339.
10. BIRSE, E.F., EATON, S.A., JANE, D.E., ST. J. JONES, P.L., PORTER, R.H.P., POOK, P.C.K., SUNTER, D.C., UDVARHELYI, P.M., WHARTON, B., ROBERTS, P.J., SALT, T.E. & WATKINS, J.C. (1993). Phenylglycine derivatives as new pharmacological tools for investigating the role of metabotropic glutamate receptors in the central nervous system. Neuroscience, 52, 481-488.
11. BLEAKMAN, D., RUSIN, K.I., CHARD, P.S., GLAUM, S.R. & MILLER, R.J. (1992). Metabotropic glutamate receptors potentiate ionotropic glutamate responses in rat dorsal horn. Mol. Pharmacol., 42, 192-196.
12. BORTOLOTTO, Z.A., BASHIR, Z.I., DAVIES, C.H. & COLLINGRIDGE, G.L. (1994). A molecular switch activated by metabotropic glutamate receptors regulates induction of long-term potentiation. Nature, 368, 740-743.
13. BRUNO, V., BATTAGLIA, G., COPANI, A., GIFFARD, R.G., RACITI, G., RAFFAELE, R., SHINOZAKI, H. & NICOLETTI, F. (1995a). Activation of class II or III metabotropic glutamate receptors protects cultured cortical neurons against excitotoxic degeneration. Eur. J. Neurosci., 7, 1906-1913.
14. BRUNO, V., COPANI, A., BATTAGLIA, G., RAFFAELE, R., SHINOZAKI, H. & NICOLETTI, F. (1994). Protective effect of the metabotropic glutamate receptor agonist, DCG-IV, against excitotoxic neuronal death. Eur. J. Pharmacol., 256, 109-112.
15. BRUNO, V., COPANI, A., KNOEPFEL, T., KUHN, R., CASABONA, G., DELL'ALBANI, P., CONDORELLI, D.F. & NICOLETTI, F. (1995b). Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology, 34, 1089-1098.
16. BUISSON, A. & CHOI, D.W. (1995). The inhibitory mGluR agonist, S-4-carboxy-3-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death. Neuropharmacology, 34, 1081-1087.
17. BUISSON, A., PING YU, S. & CHOI, D.W. (1996). DCG-IV selectively attenuates rapidly triggered NMDA-induced neurotoxicity in cortical neurons. Eur. J. Neurosci., 8, 138-143.
18. CALABRESI, P., MAJ, R., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1992a). Long-term synaptic depression in the striatum: physiological and pharmacological characterization. J. Neurosci., 12, 4224-4233.
19. CALABRESI, P., MERCURI, N.B. & BERNARDI, G. (1990a). Synaptic and intrinsic control of membrane excitability of neostriatal neurons. II. An in vitro analysis. J. Neurophysiol., 63, 663-675.
20. CALABRESI, P., MERCURI, N.B., STEFANI, A. & BERNARDI, G. (1990b). Synaptic and intrinsic control of membrane excitability of neostriatal neurons. I. An in vivo analysis. J. Neurophysiol., 63, 651-662.
21. CALABRESI, P., MERCURI, N.B. & BERNARDI, G. (1992b). Activation of quisqualate metabotropic receptors reduces glutamate and GABA-mediated synaptic potentials in the rat striatum. Neurosci. Lett., 139, 41-44.
22. CALABRESI, P., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1992c). Long-term potentiation in the striatum is unmasked by removing the voltage-dependent magnesium block of NMDA receptor channels. Eur. J. Neurosci., 4, 929-935.
23. CALABRESI, P., PISANI, A., MERCURI, N.B. & BERNARDI, G. (1996). The corticostriatal projection: from synaptic plasticity to dysfunctions of the basal ganglia. Trends Neurosci., 19, 19-24.
24. CHEN, L. & HUANG, L.Y.M. (1992). Protein kinase C reduces Mg2+ block of NMDA-receptor channels as a mechanism of modulation. Nature, 356, 521-523.
25. CHOI, D.W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron, 1, 623-634.
26. COLLINS, C.G.S. (1993). Actions of agonists of metabotropic glutamate receptors on synaptic transmission and transmitter release in the olfactory cortex. Br. J. Pharmacol., 108, 422-430.
27. COLWELL, C.S. & LEVINE, M.S. (1994). Metabotropic glutamate receptors modulate N-methyl-D-aspartate receptor function in neostriatal neurons. Neuroscience, 61, 497-507.
28. FITZJOHN, S.M., IRVING, A.J., PALMER, M.J., HARVEY, J., LODGE, D. & COLLINGRIDGE, G.L. (1996). Activation of group I mGluRs potentiates NMDA responses in rat hippocampal slices. Neurosci. Lett., 203, 211-213.
29. GLAUM, S.R., SLATER, N.T., ROSSI, D.J. & MILLER, R.J. (1992). Role of metabotropic glutamate (ACPD) receptors at the parallel fibre-purkinje cell synapse. J. Neurophysiol., 68, 1453-1462.
30. GROVES, P.M. (1983). A theory of the functional organization of the neostriatum and the neostriatal control of voluntary movement. Brain Res. Rev., 5, 109-132.
31. HARVEY, J. & COLLINGRIDGE, G.L. (1993). Signal transduction pathways involved in the acute potentiation of NMDA responses by 18,3R-ACPD in rat hippocampal slices. Br. J. Pharmacol., 109, 1085-1090.
32. HARVEY, J., FRENGUELLI, B.G., SUNTER, D.C., WATKINS, J.C. & COLLINGRIDGE, G.L. (1991). The actions of 1S,3R-ACPD, a glutamate metabotropic receptor agonist, in area CA1 of rat hippocampus. Br. J. Pharmacol., 104, 75P.
33. KAWAGUCHI, Y., WILSON, C.J. & EMSON, P.C. (1989). Intracellular recordings of identified neostriatal patch and matrix spiny cells in a slice preparation preserving cortical inputs. J. Neurophysiol., 62, 1052-1068.
34. KELSO, S.R., NELSON, T.E. & LEONARD, J.P. (1992). Protein kinase C-mediated enhancement of NMDA currents by metabotropic glutamate receptors in Xenopus oocytes. J. Physiol., 449, 705-718.
35. KINNEY, G.A. & SLATER, N.T. (1993). Potentiation of NMDA receptor-mediated transmission in turtle cerebellar granule cells by activation of metabotropic glutamate receptors. J. Neurophysiol., 69, 585-594.
36. KOH, J.Y., PAMER, E. & COTMAN, C.W. (1991). Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures. Proc. Natl. Acad. Sci. U.S.A., 88, 9431-9435.
37. KOWALL, N.W., FERRANTE, R.J. & MARTIN, J.B. (1987). Patterns of cell loss in Huntington's disease. Trends Neurosci., 10, 24-29.
38. LANDWEHRMEYER, G.B., STANDAERT, D.G., TESTA, C.M., PENNEY, J.B. JR & YOUNG, A.B. (1995). NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum. J. Neurosci., 15, 5297-5307.
39. MCGUINESS, N., ANWYL, R. & ROWAN, M. (1991). Trans-ACPD enhances long-term potentiation in the hippocampus. Eur. J. Pharmacol., 197, 231-232.
40. MONAGHAN, D.T., BRIDGES, R.J. & COTMAN, C.W. (1989). The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol., 29, 365-402.
41. MUSGRAVE, M.A., BALLYK, B.A. & GOH, J.W. (1993). Co-activation of metabotropic and NMDA receptors is required for LTP induction. NeuroReport, 4, 171-174.
42. NAKANISHI, S. (1992). Molecular diversity of glutamate receptors and implications for brain function. Science, 258, 597-603.
43. NAKANISHI, S. (1994). Metabotropic glutamate receptors: synaptic transmission, modulation and plasticity. Neuron, 13, 1031-1037.
44. NOVELLI, A., REILLY, J.A., LYSKO, P.G. & HENNEBERRY, R.C. (1988). Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res., 451, 205-212.
45. O'CONNOR, J.J., ROWAN, M.J. & ANWYL, R. (1994). Long-lasting enhancement of NMDA receptor-mediated synaptic transmission by metabotropic glutamate receptor activation. Nature, 367, 557-559.
46. ORLANDO, L.R., STANDAERT, D.G., PENNEY, J.B. & YOUNG, A.B. (1995). Metabotropic receptors in excitotoxicity: (S)-4-carboxy-3-hydroxyphenylglycine ((S)-4C3HPG) protects against rat striatal quinolinic acid lesions. Neurosci. Lett., 202, 109-112.
47. PIN, J.P. & DUVOISIN, R. (1995). Neurotransmitter receptors I. The metabotropic glutamate receptors: structure and functions. Neuropharmacology, 34, 1-26.
48. PIZZI, M., FALLACARA, C., ARRIGHI, V., MEMO, M. & SPANO, P.F. (1993). Attenuation of excitatory amino acid toxicity by metabotropic glutamate receptor agonists and aniracetam in primary cultures of cerebellar granule cells. J. Neurochem., 61, 683-689.
49. RAHMAN, S. & NEUMAN, R.S. (1996). Characterization of metabotropic glutamate receptor-mediated facilitation of N-methyl-D-aspartate depolarization of neocortical neurons. Br. J. Pharmacol., 117, 675-683.
50. REUBI, J.C. & CUENOD, M. (1979). Glutamate release in vitro from corticostriatal terminal. Brain Res., 176, 185-188.
51. ROTHMAN, S.M. & OLNEY, J.W. (1987). Excitotoxicity and NMDA receptors. Trends Neurosci., 10, 299-302.
52. SCHOEPP, D.D. & CONN, P.J. (1993). Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol. Sci., 14, 13-20.
53. SCHOEPP, D.D., GOLDSWORTHY, J., JOHNSON, B.G., SALHOFF, C.R. & BAKER, S.R. (1994). 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J. Neurochem., 63, 769-772.
54. SHIGEMOTO, R., NOMURA, S., OHISHI, H., SUGIHARA. H., NAKANISHI, S. & MIZUNO, N. (1993). Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci. Lett., 163, 53-57.
55. SILIPRANDI, R., LIPARTITI, M., FADDA, E., SAUTER, J. & MANEV, H. (1992). Activation of the glutamate metabotropic receptor protects retina against N-methyl-D-aspartate toxicity. Eur. J. Pharmacol., 219, 173-174.
56. TESTA, C.M., STANDAERT, D.G., LANDWEHRMEYER, G.B., PENNEY, J.B. & YOUNG, A.B. (1995). Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons. J. Comp. Neurol., 354, 241-252.
57. TESTA, C.M., STANDAERT, D.G., YOUNG, A.B. & PENNEY, J.B. (1994). Metabotropic glutamate receptor mRNA expression in the basal ganglia of the rat. J. Neurosci., 14, 3005-3018.
58. THOMSEN, C., BOEL, E. & SUZDAK, P.D. (1994). Actions of phenylglycine analogs at subtypes of the metabotropic glutamate receptor family. Eur. J. Pharmacol., 267, 77-84.
59. TURSKI, L. & TURSKI, W.A. (1993). Towards an understanding of the role of glutamate in neurodegenerative disorders: energy metabolism and neuropathology. Experientia, 49, 1064-1072.
60. ZEEVALK, G.D. & NICKLAS, W.J. (1991). Mechanisms underlying initiation of excitotoxicity associated with metabolic inhibition. J. Pharmacol. Exp. Ther., 257, 870-878.