Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: Implications for stress-related psychiatric disorders

Neuropsychopharmacology

Volumn 31, Issue 6, 2006, Pages 1112-1122

  Mitsukawa, Kayo ^a   Mombereau, Cedric ^a   Lötscher, Erika ^a   Uzunov, Doncho P ^a   Van Der Putten, Herman ^a   Flor, Peter J ^a   Cryan, John F ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

Author keywords

5 HT1A receptor; Anxiety; Depression; Glutamate; Group III mGluR; Hypothalamic pituitary adrenal axis

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; CORTICOTROPIN; DEXAMETHASONE SODIUM PHOSPHATE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; METABOTROPIC RECEPTOR 7; SEROTONIN 1A RECEPTOR; TRANSCRIPTION FACTOR;

ADRENAL GLAND WEIGHT; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BODY WEIGHT; BRAIN REGION; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOTROPIN BLOOD LEVEL; DEPRESSION; DEXAMETHASONE SUPPRESSION TEST; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; MOOD DISORDER; MOUSE; NEGATIVE FEEDBACK; NEUROTRANSMISSION; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGAN WEIGHT; PHENOTYPE; PRIORITY JOURNAL; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; STRESS;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; BODY WEIGHT; BRAIN-DERIVED NEUROTROPHIC FACTOR; DEXAMETHASONE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HIPPOCAMPUS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IMMUNOASSAY; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PITUITARY-ADRENAL SYSTEM; RADIOIMMUNOASSAY; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTORS, GLUCOCORTICOID; RECEPTORS, METABOTROPIC GLUTAMATE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STRESS;

EID: 33745675486     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300926     Document Type: Article

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