The mGluR5 antagonist MPEP selectively inhibits the onset and maintenance of ethanol self-administration in C57BL/6J mice

Psychopharmacology

Volumn 183, Issue 4, 2006, Pages 429-438

  Hodge, Clyde W ^a   Miles, Michael F ^b   Sharko, Amanda C ^a   Stevenson, Rebekah A ^a   Hillmann, Jennie R ^a   Lepoutre, Veronique ^a   Besheer, Joyce ^a   Schroeder, Jason P ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Alcohol drinking; Ethanol self administration; mGluR1; mGluR2 3; mGluR5; Mice; MPEP; Reinforcement

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 7 (HYDROXYIMINO)CYCLOPROPA[B]CHROMEN 1A CARBOXYLATE ETHYL ESTER; ALCOHOL; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; DOSE RESPONSE; DRINKING BEHAVIOR; DRUG ABUSE; LATENT PERIOD; LOCOMOTION; MALE; MOUSE; NONHUMAN; PEAK EXPIRATORY FLOW; PRIORITY JOURNAL; REDUCTION;

ALCOHOL DRINKING; ANIMALS; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING, OPERANT; ETHANOL; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; PYRIDINES; RECEPTORS, METABOTROPIC GLUTAMATE; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION;

EID: 28344451556     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-005-0217-y     Document Type: Article

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