Antinociceptive effects following intrathecal pretreatment with selective metabotropic glutamate receptor compounds in a rat model of neuropathic pain

Pharmacology Biochemistry and Behavior

Volumn 73, Issue 2, 2002, Pages 411-418

  Fisher, Kim ^a,b   Lefebvre, Celeste ^a   Coderre, Terence J ^a,b,c  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

Author keywords

Chronic constriction injury; Mechanical and cold hypersensitivity; Metabotropic glutamate receptors; mGluR; Neuropathic pain

Indexed keywords

1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 AMINOPYRROLIDINE 2,4 DICARBOXYLATE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR AGONIST; METABOTROPIC RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; 1-AMINOINDAN-1,5-DICARBOXYLIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; ANALGESIC AGENT; INDAN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; COLD SENSITIVITY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG MECHANISM; MALE; NERVE COMPRESSION; NEUROPATHY; NONHUMAN; PAIN; PHYSICAL SENSITIVITY; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SCIATIC NERVE; TIME; ANIMAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; INTRASPINAL DRUG ADMINISTRATION; LONG EVANS RAT; PAIN ASSESSMENT; PAIN THRESHOLD; PATHOLOGY; PERIPHERAL NEUROPATHY; STENOSIS, OCCLUSION AND OBSTRUCTION;

ANALGESICS; ANIMAL; CONSTRICTION, PATHOLOGIC; EXCITATORY AMINO ACID ANTAGONISTS; INDANS; INJECTIONS, SPINAL; MALE; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PERIPHERAL NERVOUS SYSTEM DISEASES; RATS; RATS, LONG-EVANS; RECEPTORS, METABOTROPIC GLUTAMATE; SUPPORT, NON-U.S. GOV'T; ANIMALS;

EID: 0035996515     PISSN: 00913057     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-3057(02)00832-8     Document Type: Article

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