A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5

Molecular Pharmacology

Volumn 64, Issue 3, 2003, Pages 731-740

  O'Brien, Julie A ^a   Lemaire, Wei ^a   Chen, Tsing Bau ^a   Chang, Raymond S L ^a   Jacobson, Marlene A ^a   Ha, Sookhee N ^a   Lindsley, Craig W ^a   Schaffhauser, Hervé J ^a   Sur, Cyrille ^a   Pettibone, Douglas J ^a   Conn, P Jeffrey ^a   Williams Jr , David L ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3 METHOXY 5 (2 PYRIDINYLETHYNYL)PYRIDINE; 3,3' DICHLOROBENZALDAZINE; 3,3' DIFLUOROBENZALDAZINE; 3,3' DIMETHOXYBENZALDAZINE; 3,5 DIHYDROXYPHENYLGLYCINE; GLUTAMATE 5 RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; QUISQUALIC ACID; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG ACTIVITY; FLUOROMETRY; HUMAN; HUMAN CELL; IC 50; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; RAT; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ANIMALS; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; HUMANS; PROTEIN BINDING; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0041353568     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.3.731     Document Type: Article

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