Suppression of alcohol self-administration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3,4-DCPG

European Journal of Pharmacology

Volumn 528, Issue 1-3, 2005, Pages 110-118

  Bäckström, Pia ^a   Hyytiä, Petri ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Alcohol; Conditioning; Glutamate; Metabotropic glutamate receptor; Reinstatement; Self administration

Indexed keywords

3,4 DICARBOXYPHENYLGLYCINE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; ALCOHOL; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 3; GLUTAMATE RECEPTOR AGONIST; QUININE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ATTENUATION; DRUG SELF ADMINISTRATION; LOCOMOTION; MALE; MODULATION; NONHUMAN; PHOTOSTIMULATION; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; STIMULUS RESPONSE; TRAINING;

ALCOHOL DRINKING; AMINO ACIDS; ANIMALS; BEHAVIOR, ADDICTIVE; BEHAVIOR, ANIMAL; BENZOATES; BICYCLO COMPOUNDS, HETEROCYCLIC; CONDITIONING, OPERANT; CUES; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; GLYCINE; LIGHT; MALE; MOTOR ACTIVITY; RATS; RATS, LONG-EVANS; RECEPTORS, METABOTROPIC GLUTAMATE; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION; SMELL; TIME FACTORS;

EID: 28844433298     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.10.051     Document Type: Article

References (45)

1. A.T. Alleweireldt, S.M. Weber, K.F. Kirschner, B.L. Bullock, and J.L. Neisewander Blockade or stimulation of D1 dopamine receptors attenuates cue reinstatement of extinguished cocaine-seeking behavior in rats Psychopharmacology 159 2002 284 293
2. M.A. Baptista, R. Martin-Fardon, and F. Weiss Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement versus primary reinforcement: comparison between cocaine and a potent conventional reinforcer J. Neurosci. 24 2004 4723 4727
3. K. Bell, P. Duffy, and P.W. Kalivas Context-specific enhancement of glutamate transmission by cocaine Neuropsychopharmacology 23 2000 335 344
4. A. Bespalov The expression of both amphetamine-conditioned place preference and pentylenetetrazol-conditioned place aversion is attenuated by the NMDA receptor antagonist (+/-)-CPP Drug Alcohol Depend. 41 1996 85 88
5. J.M. Bossert, S.Y. Liu, L. Lu, and Y. Shaham A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking J. Neurosci. 24 2004 10726 10730
6. P. Bäckström, and P. Hyytiä Attenuation of cocaine-seeking behaviour by the AMPA/kainate receptor antagonist CNQX in rats Psychopharmacology 166 2003 69 76
7. P. Bäckström, and P. Hyytiä Ionotropic glutamate receptor antagonists modulate cue-induced reinstatement of ethanol-seeking behavior Alcohol., Clin. Exp. Res. 28 2004 558 565
8. J. Cartmell, J.A. Monn, and D.D. Schoepp The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-amphetamine motor behaviors in rats J. Pharmacol. Exp. Ther. 291 1999 161 170
9. J. Cartmell, J.A. Monn, and D.D. Schoepp Tolerance to the motor impairment, but not to the reversal of PCP-induced motor activities by oral administration of the mGlu2/3 receptor agonist, LY379268 Naunyn-Schmiedeberg's Arch. Pharmacol. 361 2000 39 46
10. R. Ciccocioppo, S. Angeletti, and F. Weiss Long-lasting resistance to extinction of response reinstatement induced by ethanol-related stimuli: role of genetic ethanol preference Alcohol., Clin. Exp. Res. 25 2001 1414 1419
11. M. Clark, B.G. Johnson, R.A. Wright, J.A. Monn, and D.D. Schoepp Effects of the mGlu2/3 receptor agonist LY379268 on motor activity in phencyclidine-sensitized rats Pharmacol. Biochem. Behav. 73 2002 339 346
12. N.L. Cooney, M.D. Litt, P.A. Morse, L.O. Bauer, and L. Gaupp Alcohol cue reactivity, negative-mood reactivity, and relapse in treated alcoholic men J. Abnorm. Psychology 106 1997 243 250
13. J.L. Cornish, and P.W. Kalivas Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction J. Neurosci. 20 2000 1 5
14. J.L. Cornish, P. Duffy, and P.W. Kalivas A role for nucleus accumbens glutamate transmission in the relapse to cocaine-seeking behavior Neuroscience 93 1999 1359 1367
15. H.S. Crombag, J.W. Grimm, and Y. Shaham Effect of dopamine receptor antagonists on renewal of cocaine seeking by reexposure to drug-associated contextual cues Neuropsychopharmacology 27 2002 1006 1015
16. H. de Wit, and M.A. Chutuape Increased ethanol choice in social drinkers following ethanol preload Behav. Pharmacol. 4 1993 29 36
17. P. Di Ciano, and B.J. Everitt Dissociable effects of antagonism of NMDA and AMPA/KA receptors in the nucleus accumbens core and shell on cocaine-seeking behavior Neuropsychopharmacology 25 2001 341 360
18. J.D. Greeley, W. Swift, J. Prescott, and N. Heather Reactivity to alcohol-related cues in heavy and light drinkers J. Stud. Alcohol 54 1993 359 368
19. S.M. Grüsser, J. Wrase, S. Klein, D. Hermann, M.N. Smolka, M. Ruf, W. Weber-Fahr, H. Flor, K. Mann, D.F. Braus, and A. Heinz Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics Psychopharmacology 175 2004 296 302
20. G. Hotsenpiller, M. Giorgetti, and M.E. Wolf Alterations in behaviour and glutamate transmission following presentation of stimuli previously associated with cocaine exposure Eur. J. Neurosci. 14 2001 1843 1855
21. R. Ito, J.W. Dalley, S.R. Howes, T.W. Robbins, and B.J. Everitt Dissociation in conditioned dopamine release in the nucleus accumbens core and shell in response to cocaine cues and during cocaine-seeking behavior in rats J. Neurosci. 20 2000 7489 7495
22. A. Jackson, A.N. Mead, B.A. Rocha, and D.N. Stephens AMPA receptors and motivation for drug: effect of the selective antagonist NBQX on behavioural sensitization and on self-administration in mice Behav. Pharmacol. 9 1998 457 467
23. S. Katner, and F. Weiss Ethanol-associated olfactory stimuli reinstate ethanol-seeking behavior after extinction and modify extracellular dopamine levels in the nucleus accumbens Alcohol., Clin. Exp. Res. 23 1999 1751 1760
24. S.N. Katner, J.G. Magalong, and F. Weiss Reinstatement of alcohol-seeking behavior by drug-associated discriminative stimuli after prolonged extinction in the rat Neuropsychopharmacology 20 1999 471 479
25. J.H. Kim, J.D. Austin, L. Tanabe, E. Creekmore, and P. Vezina Activation of group II mGlu receptors blocks the enhanced drug taking induced by previous exposure to amphetamine Eur. J. Neurosci. 21 2005 295 300
26. J. Kotlinska, and G. Biala Memantine and ACPC affect conditioned place preference induced by cocaine in rats Pol. J. Pharmacol. 52 2000 179 185
27. A.M. Linden, M. Bergeron, M. Baez, and D.D. Schoepp Systemic administration of the potent mGlu8 receptor agonist (S)-3,4-DCPG induces c-Fos in stress-related brain regions in wild-type, but not mGlu8 receptor knockout mice Neuropharmacology 45 2003 473 483
28. X. Liu, and F. Weiss Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: differences in antagonist potency in previously ethanol-dependent versus nondependent rats J. Pharmacol. Exp. Ther. 300 2002 882 889
29. K. McFarland, C.C. Lapish, and P.W. Kalivas Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior J. Neurosci. 23 2003 3531 3537
30. A.N. Mead, and D.N. Stephens AMPA-receptors are involved in the expression of amphetamine-induced behavioural sensitisation, but not in the expression of amphetamine-induced conditioned activity in mice Neuropharmacology 37 1998 1131 1138
31. R.X. Moldrich, P.M. Beart, D.E. Jane, A.G. Chapman, and B.S. Meldrum Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice Neuropharmacology 40 2001 732 735
32. J.A. Monn, M.J. Valli, S.M. Massey, M.M. Hansen, T.J. Kress, J.P. Wepsiec, A.R. Harkness, J.L. Grutsch Jr., R.A. Wright, B.G. Johnson, S.L. Andis, A. Kingston, R. Tomlinson, R. Lewis, K.R. Griffey, J.P. Tizzano, and D.D. Schoepp Synthesis, pharmacological characterization, and molecular modeling of heterobicyclic amino acids related to (+)-2-aminobicyclo[3.1.0] hexane-2,6-dicarboxylic acid (LY354740): identification of two new potent, selective, and systemically active agonists for group II metabotropic glutamate receptors J. Med. Chem. 42 1999 1027 1040
33. H. Nie, and P.H. Janak Comparison of reinstatement of ethanol- and sucrose-seeking by conditioned stimuli and priming injections of allopregnanolone after extinction in rats Psychopharmacology 168 2003 222 228
34. K. Ossowska, M. Pietraszek, J. Wardas, and S. Wolfarth Potential antipsychotic and extrapyramidal effects of (R,S)-3,4-dicarboxyphenylglycine [(R,S)-3,4-DCPG], a mixed AMPA antagonist/mGluR8 agonist Pol. J. Pharmacol. 56 2004 295 304
35. W.K. Park, A.A. Bari, A.R. Jey, S.M. Anderson, R.D. Spealman, J.K. Rowlett, and R.C. Pierce Cocaine administered into the medial prefrontal cortex reinstates cocaine-seeking behavior by increasing AMPA receptor-mediated glutamate transmission in the nucleus accumbens J. Neurosci. 22 2002 2916 2925
36. P. Popik, M. Wrobel, R. Rygula, A. Bisaga, and A.Y. Bespalov Effects of memantine, an NMDA receptor antagonist, on place preference conditioned with drug and nondrug reinforcers in mice Behav. Pharmacol. 14 2003 237 244
37. C.A. Pothecary, D.E. Jane, and T.E. Salt Reduction of excitatory transmission in the retino-collicular pathway via selective activation of mGlu8 receptors by DCPG Neuropharmacology 43 2002 231 234
38. H.H. Samson Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats Alcohol., Clin. Exp. Res. 10 1986 436 442
39. H.H. Samson, and A.M. Chappell Effects of raclopride in the core of the nucleus accumbens on ethanol seeking and consumption: the use of extinction trials to measure seeking Alcohol., Clin. Exp. Res. 28 2004 544 549
40. F. Schneider, U. Habel, M. Wagner, P. Franke, J.B. Salloum, N.J. Shah, I. Toni, C. Sulzbach, K. Hönig, W. Maier, W. Gaebel, and K. Zilles Subcortical correlates of craving in recently abstinent alcoholic patients Am. J. Psychiatry 158 2001 1075 1083
41. D.D. Schoepp Unveiling the functions of presynaptic metabotropic glutamate receptors in the central nervous system J. Pharmacol. Exp. Ther. 299 2001 12 20
42. N.K. Thomas, R.A. Wright, P.A. Howson, A.E. Kingston, D.D. Schoepp, and D.E. Jane (S)-3,4-DCPG, a potent and selective mGlu8a receptor agonist, activates metabotropic glutamate receptors on primary afferent terminals in the neonatal rat spinal cord Neuropharmacology 40 2001 311 318
43. S.T. Tiffany, and B.L. Carter Is craving the source of compulsive drug use? J. Psychopharmacol. 12 1998 23 30
44. F. Weiss, C.S. Maldonado-Vlaar, J.H. Parsons, T.M. Kerr, D.L. Smith, and O. Ben-Shahar Control of cocaine-seeking behavior by drug-associated stimuli in rats: effects on recovery of extinguished operant-responding and extracellular dopamine levels in amygdala and nucleus accumbens Proc. Natl. Acad. Sci. U. S. A. 97 2000 4321 4326
45. Z.X. Xi, S. Ramamoorthy, D.A. Baker, H. Shen, D.J. Samuvel, and P.W. Kalivas Modulation of group II metabotropic glutamate receptor signaling by chronic cocaine J. Pharmacol. Exp. Ther. 303 2002 608 615