Metabotropic glutamate 5 receptor (mGluR5) antagonists decrease nicotine seeking, but do not affect the reinforcement enhancing effects of nicotine

Neuropsychopharmacology

Volumn 33, Issue 9, 2008, Pages 2139-2147

  Palmatier, Matthew I ^a,b   Liu, Xiu ^a   Donny, Eric C ^a   Caggiula, Anthony R ^a   Sved, Alan F ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

Author keywords

Glutamate; Metabotropic; Nicotine; Reinforcement

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 3 [(2 METHYL 4 THIAZOLYL)ETHYNYL]PYRIDINE; METABOTROPIC RECEPTOR 5 ANTAGONIST; METABOTROPIC RECEPTOR ANTAGONIST; NICOTINE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EVALUATION; EXPERIMENTAL MODEL; INFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SMOKING CESSATION; VISUAL STIMULATION; WITHDRAWAL SYNDROME;

ANIMALS; BEHAVIOR, ANIMAL; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EXCITATORY AMINO ACID ANTAGONISTS; MALE; NICOTINE; NICOTINIC AGONISTS; PHOTIC STIMULATION; PYRIDINES; RATS; RATS, SPRAGUE-DAWLEY; REINFORCEMENT (PSYCHOLOGY); SELF ADMINISTRATION; THIAZOLES; TOBACCO USE DISORDER;

EID: 47249104677     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1301623     Document Type: Article

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