Metabotropic glutamate 2 receptor potentiators: Receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s)

Psychopharmacology

Volumn 179, Issue 1, 2005, Pages 271-283

  Johnson, Michael P ^a   Barda, David ^a   Britton, Thomas C ^a   Emkey, Renee ^a   Hornback, William J ^a   Jagdmann, G Erik ^a   McKinzie, David L ^a   Nisenbaum, Eric S ^a   Tizzano, Joseph P ^a   Schoepp, Darryle D ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2,3 DICARBOXYCYCLOPROPYL)GLYCINE; 2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; 2,2,2 TRIFLUORO N [3 (2 METHOXYPHENOXY)PHENYL] N (3 PYRIDINYLMETHYL) ETHANESULFONAMIDE; 2,2,2 TRIFLUORO N [3 (CYCLOPENTYLOXY)PHENYL] N (3 PYRIDINYLMETHYL) ETHANESULFONAMIDE; 2,2,2 TRIFLUORO N [4 (2 METHOXYPHENOXY)PHENYL] N (3 PYRIDINYLMETHYL) ETHANESULFONAMIDE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; DIAZEPAM; EGLUMETAD; LY 487379; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR AGONIST; N (4' CYANOBIPHENYL 3 YL) N (3 PYRIDINYLMETHYL)ETHANESULFONAMIDE; N [4 (4 CARBOXAMIDOPHENOXY)PHENYL] N (3 PYRIDINYLMETHYL)ETHANESULFONAMIDE; PHENCYCLIDINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BINDING AFFINITY; BRAIN TISSUE; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFICACY; FEAR; FREQUENCY MODULATION; HYPERTHERMIA; ISOTOPE LABELING; MALE; MENTAL DISEASE; MOTOR ACTIVITY; NONHUMAN; PRESYNAPTIC POTENTIAL; PRIORITY JOURNAL; PSYCHOSIS; RAT; SENSITIVITY ANALYSIS; STARTLE REFLEX; STRESS; SYNAPSE; SYNAPTIC TRANSMISSION;

ANIMALS; ANXIETY; CYCLOPROPANES; EXCITATORY AMINO ACID AGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLYCINE; HUMANS; MALE; MICE; MICE, INBRED DBA; MICE, INBRED ICR; MOTOR ACTIVITY; PHENCYCLIDINE; PSYCHOTIC DISORDERS; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 20944447548     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-004-2099-9     Document Type: Article

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