Glutamine synthetase down-regulation reduces astrocyte protection against glutamate excitotoxicity to neurons

Neurochemistry International

Volumn 56, Issue 4, 2010, Pages 577-584

  Zou, Jian ^a   Wang, Yan Xia ^a   Dou, Fang Fang ^a   Lü, He Zuo ^a   Ma, Zheng Wen ^a   Lu, Pei Hua ^a   Xu, Xiao Ming ^a,b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Astrocyte; Glutamate; Glutamate uptake; Glutamine; Glutamine synthetase; Neuroexcitotoxicity; TNF

Indexed keywords

GLUTAMATE AMMONIA LIGASE; GLUTAMIC ACID; GLUTAMINE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME INDUCTION; ENZYME INHIBITION; EXCITOTOXICITY; GENE TRANSFER; IN VITRO STUDY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TARGETING; RAT;

ANIMALS; APOPTOSIS; ASTROCYTES; BLOTTING, WESTERN; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; EXCITATORY AMINO ACIDS; GLUTAMATE-AMMONIA LIGASE; GLUTAMIC ACID; NERVE DEGENERATION; NEURONS; PLASMIDS; RATS; RATS, SPRAGUE-DAWLEY; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77249122078     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2009.12.021     Document Type: Article

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