The mGluR2 positive allosteric modulator BINA decreases cocaine Self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats

Neuropsychopharmacology

Volumn 35, Issue 10, 2010, Pages 2021-2036

  Jin, Xinchun ^a   Semenova, Svetlana ^a   Yang, Li ^b   Ardecky, Robert ^b   Sheffler, Douglas J ^c   Dahl, Russell ^b   Conn, P Jeffrey ^c   Cosford, Nicholas Dp ^b   Markou, Athina ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BURNHAM INSTITUTE   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BINA; food responding; food seeking; Glutamate; intracranial self stimulation; LY379268

Indexed keywords

3' ([(2 CYCLOPENTYL 6,7 DIMETHYL 1 OXO 2,3 DIHYDRO 1H INDEN 5 YL)OXY]METHYL]BIPHENYL 1 4 CARBOXYLATE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; CARBOXYLIC ACID DERIVATIVE; COCAINE; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; COCAINE DEPENDENCE; CONTROLLED STUDY; DRUG SELF ADMINISTRATION; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; REWARD; SELF STIMULATION;

AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; BICYCLO COMPOUNDS, HETEROCYCLIC; BIPHENYL COMPOUNDS; BRAIN; CELL LINE, TRANSFORMED; COCAINE; CUES; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; EXCITATORY AMINO ACID AGONISTS; EXTINCTION, PSYCHOLOGICAL; FEEDING BEHAVIOR; GLUTAMIC ACID; HUMANS; INDANS; MALE; RATS; RATS, WISTAR; RECEPTORS, METABOTROPIC GLUTAMATE; REINFORCEMENT SCHEDULE; REWARD; SELF ADMINISTRATION; TIME FACTORS;

EID: 77955717226     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.82     Document Type: Article

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