Metabotropic Glutamate Receptor 5 Activity in the Nucleus Accumbens Is Required for the Maintenance of Ethanol Self-Administration in a Rat Genetic Model of High Alcohol Intake

Biological Psychiatry

Volumn 67, Issue 9, 2010, Pages 812-822

  Besheer, Joyce ^a,b   Grondin, Julie J M ^a   Cannady, Reginald ^a,b   Sharko, Amanda C ^a   Faccidomo, Sara ^a   Hodge, Clyde W ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Alcohol drinking; alcoholism; caudate; LY379268; mGluR2 3; mGluR5; MPEP; nucleus accumbens; P rats; prefrontal cortex; reinforcement; self administration

Indexed keywords

2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; METABOTROPIC RECEPTOR 2; METABOTROPIC RECEPTOR 3; METABOTROPIC RECEPTOR 5;

ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; LIMBIC CORTEX; MOTOR ACTIVITY; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

ALCOHOL DRINKING; AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BICYCLO COMPOUNDS, HETEROCYCLIC; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CONDITIONING, OPERANT; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHANOL; EXCITATORY AMINO ACID AGENTS; FOOD PREFERENCES; MALE; MICROINJECTIONS; MOTOR ACTIVITY; NUCLEUS ACCUMBENS; PYRIDINES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; REINFORCEMENT SCHEDULE; SELF ADMINISTRATION; SUCROSE; SWEETENING AGENTS;

EID: 77950356499     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2009.09.016     Document Type: Article

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