Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP

Journal of Neuroscience

Volumn 17, Issue 13, 1997, Pages 5196-5205

  Lu, You Ming ^a   Jia, Zhengping ^a   Janus, Christopher ^a   Henderson, Jeffrey T ^a   Gerlai, Robert ^a   Wojtowicz, J Martin ^b   Roder, John C ^a  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Gene targeting; Hippocampus; Long term potentiation; Metabotropic glutamate receptor 5; Spatial learning; Synaptic function

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; EXCITATORY POSTSYNAPTIC POTENTIAL; FEAR; GENE TARGETING; LEARNING; LEARNING DISORDER; LONG TERM POTENTIATION; MAZE TEST; MOSSY FIBER; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL;

EID: 0030954048     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-13-05196.1997     Document Type: Article

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