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Volumn 53, Issue 1-2, 1998, Pages 88-97

Group III human metabotropic glutamate receptors 4, 7 and 8: Molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells

Author keywords

Cloning; Complementary DNA; Cyclic AMP; L 2 Amino 4 phosphonobutyrate; L glutamate; Metabotropic glutamate receptors; Nucleotides

Indexed keywords

AMINO ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR STIMULATING AGENT; CARRIER PROTEIN; COMPLEMENTARY DNA; CYCLIC AMP; FORSKOLIN; GLUTAMIC ACID; METABOTROPIC RECEPTOR;

EID: 0031950950     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00277-5     Document Type: Article
Times cited : (106)

References (46)
  • 1
    • 0025338354 scopus 로고
    • Excitatory amino acid receptors and synaptic plasticity
    • Collingridge G.L., Singer W. Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol. Sci. 11:1990;290-296.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 290-296
    • Collingridge, G.L.1    Singer, W.2
  • 3
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum B., Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11:1990;379-387.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 4
    • 0026437728 scopus 로고
    • Molecular diversity of glutamate receptors and implications in brain function
    • Nakanishi S. Molecular diversity of glutamate receptors and implications in brain function. Science. 258:1992;597-603.
    • (1992) Science , vol.258 , pp. 597-603
    • Nakanishi, S.1
  • 5
    • 0027395275 scopus 로고
    • Metabotropic glutamate receptors in brain function and pathology
    • Schoepp D., Conn P.J. Metabotropic glutamate receptors in brain function and pathology. Trends Pharmacol. Sci. 14:1993;13-20.
    • (1993) Trends Pharmacol. Sci. , vol.14 , pp. 13-20
    • Schoepp, D.1    Conn, P.J.2
  • 7
    • 0024596865 scopus 로고
    • The excitatory amino acid receptors: Their classes, pharmacology and distinct properties in the function of the central nervous system
    • Monaghan D.T., Bridges R.J., Cotman C.W. The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. Annu. Rev. Pharmacol. Toxicol. 29:1989;365-402.
    • (1989) Annu. Rev. Pharmacol. Toxicol. , vol.29 , pp. 365-402
    • Monaghan, D.T.1    Bridges, R.J.2    Cotman, C.W.3
  • 8
    • 0025681068 scopus 로고
    • Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors
    • Schoepp D., Bockaert J., Sladeczek F. Pharmacological and functional characteristics of metabotropic excitatory amino acid receptors. Trends Pharmacol. Sci. 11:1990;508-515.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 508-515
    • Schoepp, D.1    Bockaert, J.2    Sladeczek, F.3
  • 9
    • 0026093312 scopus 로고
    • Sequence and expression of a metabotropic glutamate receptor
    • Masu M., Tanabe Y., Tsuchida K., Shigemoto R., Nakanishi S. Sequence and expression of a metabotropic glutamate receptor. Nature. 349:1991;760-765.
    • (1991) Nature , vol.349 , pp. 760-765
    • Masu, M.1    Tanabe, Y.2    Tsuchida, K.3    Shigemoto, R.4    Nakanishi, S.5
  • 12
    • 0028968702 scopus 로고
    • A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb
    • Duvoisin R.M., Zhang C., Ramonell K. A novel metabotropic glutamate receptor expressed in the retina and olfactory bulb. J. Neurosci. 15:1995;3075-3083.
    • (1995) J. Neurosci. , vol.15 , pp. 3075-3083
    • Duvoisin, R.M.1    Zhang, C.2    Ramonell, K.3
  • 13
    • 0028938193 scopus 로고
    • Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 4
    • Flor P.J., Lukic S., Ruegg D., Leonhardt T., Knopfel T., Kuhn R. Molecular cloning, functional expression and pharmacological characterization of the human metabotropic glutamate receptor type 4. Neuropharmacology. 34:1995;149-155.
    • (1995) Neuropharmacology , vol.34 , pp. 149-155
    • Flor, P.J.1    Lukic, S.2    Ruegg, D.3    Leonhardt, T.4    Knopfel, T.5    Kuhn, R.6
  • 14
    • 0024367836 scopus 로고
    • Cloning by functional expression of a member of the glutamate receptor family
    • Hollmann M., O'Shea-Greenfield A., Rogers S.W., Heinemann S. Cloning by functional expression of a member of the glutamate receptor family. Nature. 342:1989;643-648.
    • (1989) Nature , vol.342 , pp. 643-648
    • Hollmann, M.1    O'Shea-Greenfield, A.2    Rogers, S.W.3    Heinemann, S.4
  • 16
    • 0028928489 scopus 로고
    • Metabotropic glutamate receptors: Novel targets for drug development
    • Knopfel T., Kuhn R., Allgeier H. Metabotropic glutamate receptors: novel targets for drug development. J. Med. Chem. 38:1995;1417-1426.
    • (1995) J. Med. Chem. , vol.38 , pp. 1417-1426
    • Knopfel, T.1    Kuhn, R.2    Allgeier, H.3
  • 17
    • 0029871853 scopus 로고    scopus 로고
    • Molecular characterization and localization of human metabotropic glutamate receptor type 4
    • Makoff A., Lelchuk R., Oxer M., Harrington K., Emson P. Molecular characterization and localization of human metabotropic glutamate receptor type 4. Mol. Brain Res. 37:1996;239-248.
    • (1996) Mol. Brain Res. , vol.37 , pp. 239-248
    • Makoff, A.1    Lelchuk, R.2    Oxer, M.3    Harrington, K.4    Emson, P.5
  • 18
    • 0030221646 scopus 로고    scopus 로고
    • Human metabotropic glutamate receptor type 7: Molecular cloning and mRNA distribution in the CNS
    • Makoff A., Pilling C., Harrington K., Emsen P. Human metabotropic glutamate receptor type 7: molecular cloning and mRNA distribution in the CNS. Mol. Brain Res. 40:1996;165-170.
    • (1996) Mol. Brain Res. , vol.40 , pp. 165-170
    • Makoff, A.1    Pilling, C.2    Harrington, K.3    Emsen, P.4
  • 19
    • 0030221653 scopus 로고    scopus 로고
    • Molecular characterization and localization of human metabotropic glutamate receptor type 3
    • Makoff A., Volpe F., Lelchuk R., Harrington K., Emson P. Molecular characterization and localization of human metabotropic glutamate receptor type 3. Mol. Brain Res. 40:1996;55-63.
    • (1996) Mol. Brain Res. , vol.40 , pp. 55-63
    • Makoff, A.1    Volpe, F.2    Lelchuk, R.3    Harrington, K.4    Emson, P.5
  • 20
    • 0027232329 scopus 로고
    • Molecular characterization of novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate
    • Nakajima Y., Iwakabe H., Akazawa C., Nawa H., Shigemoto R., Mizuno N., Nakanishi S. Molecular characterization of novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate. J. Biol. Chem. 268:1993;11868-11873.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11868-11873
    • Nakajima, Y.1    Iwakabe, H.2    Akazawa, C.3    Nawa, H.4    Shigemoto, R.5    Mizuno, N.6    Nakanishi, S.7
  • 21
    • 0027955170 scopus 로고
    • Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction
    • Okamoto N., Hori S., Akazawa C., Hayashi Y., Shigemoto R., Mizuno N., Nakanishi S. Molecular characterization of a new metabotropic glutamate receptor mGluR7 coupled to inhibitory cyclic AMP signal transduction. J. Biol. Chem. 269:1994;1231-1236.
    • (1994) J. Biol. Chem. , vol.269 , pp. 1231-1236
    • Okamoto, N.1    Hori, S.2    Akazawa, C.3    Hayashi, Y.4    Shigemoto, R.5    Mizuno, N.6    Nakanishi, S.7
  • 22
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin J.-P., Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology. 34:1995;1-26.
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.-P.1    Duvoisin, R.2
  • 23
    • 0028207306 scopus 로고
    • Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid sensitive class of metabotropic glutamate receptors
    • Saugstad J.A., Kinzie J.M., Mulvihill E.R., Segerson T.P., Westbrook G.L. Cloning and expression of a new member of the L-2-amino-4-phosphonobutyric acid sensitive class of metabotropic glutamate receptors. Mol. Pharmacol. 45:1994;367-372.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 367-372
    • Saugstad, J.A.1    Kinzie, J.M.2    Mulvihill, E.R.3    Segerson, T.P.4    Westbrook, G.L.5
  • 24
    • 0027410488 scopus 로고
    • Signal transduction, pharmacological properties and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4
    • Tanabe Y., Nomura A., Masu M., Shigemoto R., Mizuno N., Nakanishi S. Signal transduction, pharmacological properties and expression patterns of two rat metabotropic glutamate receptors, mGluR3 and mGluR4. J. Neurosci. 13:1993;1372-1378.
    • (1993) J. Neurosci. , vol.13 , pp. 1372-1378
    • Tanabe, Y.1    Nomura, A.2    Masu, M.3    Shigemoto, R.4    Mizuno, N.5    Nakanishi, S.6
  • 25
    • 0026802260 scopus 로고
    • L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase
    • Thomsen C., Kristensen P., Mulvihill E., Haldeman B., Suzadak P.D. L-2-amino-4-phosphonobutyrate (L-AP4) is an agonist at the type IV metabotropic glutamate receptor which is negatively coupled to adenylate cyclase. Eur. J. Pharmacol. 227:1992;361-362.
    • (1992) Eur. J. Pharmacol. , vol.227 , pp. 361-362
    • Thomsen, C.1    Kristensen, P.2    Mulvihill, E.3    Haldeman, B.4    Suzadak, P.D.5
  • 26
    • 0026756866 scopus 로고
    • Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells
    • Hayashi Y., Tanabe Y., Aramori I., Masu M., Shimamoto K., Ohfune Y., Nakanishi S. Agonist analysis of 2-(carboxycyclopropyl)glycine isomers for cloned metabotropic glutamate receptor subtypes expressed in Chinese hamster ovary cells. Br. J. Pharmacol. 107:1992;539-543.
    • (1992) Br. J. Pharmacol. , vol.107 , pp. 539-543
    • Hayashi, Y.1    Tanabe, Y.2    Aramori, I.3    Masu, M.4    Shimamoto, K.5    Ohfune, Y.6    Nakanishi, S.7
  • 28
    • 0029113130 scopus 로고
    • Selective inhibiton of forskolin stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R, 4R-4-amino-pyrrolidine-2,4-dicarboxylate
    • Schoepp D.D., Johnson B.G., Salhoff C.R., Valli M.J., Desai M.A., Burnett J.P., Mayne N.G., Monn J.A. Selective inhibiton of forskolin stimulated cyclic AMP formation in rat hippocampus by a novel mGluR agonist, 2R, 4R-4-amino-pyrrolidine-2,4-dicarboxylate. Neuropharmacology. 34:1995;843-850.
    • (1995) Neuropharmacology , vol.34 , pp. 843-850
    • Schoepp, D.D.1    Johnson, B.G.2    Salhoff, C.R.3    Valli, M.J.4    Desai, M.A.5    Burnett, J.P.6    Mayne, N.G.7    Monn, J.A.8
  • 29
    • 0030483690 scopus 로고    scopus 로고
    • The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: Evidence for a synergistic interaction between group 1 and group 2 receptors
    • Schoepp D.D., Salhoff C.R., Wright R.A., Johnson B.G., Burnett J.P., Mayne N.G., Belagaje R., Wu S., Monn J.A. The novel metabotropic glutamate receptor agonist 2R,4R-APDC potentiates stimulation of phosphoinositide hydrolysis in the rat hippocampus by 3,5-dihydroxyphenylglycine: Evidence for a synergistic interaction between group 1 and group 2 receptors. Neuropharmacology. 35:1996;1661-1672.
    • (1996) Neuropharmacology , vol.35 , pp. 1661-1672
    • Schoepp, D.D.1    Salhoff, C.R.2    Wright, R.A.3    Johnson, B.G.4    Burnett, J.P.5    Mayne, N.G.6    Belagaje, R.7    Wu, S.8    Monn, J.A.9
  • 30
    • 15644369847 scopus 로고    scopus 로고
    • Design, synthesis and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: A potent, selective, systemically active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties
    • Monn J.A., Valli M.J., Massey S.M., Wright R.A., Salhoff C.R., Johnson B.G., Howe T., Alt C.A., Rhodes G.A., Robey R.L., Griffey K.R., Tizzano J.P., Kallma M.J., Helton D.R., Schoepp D.D. Design, synthesis and pharmacological characterization of (+)-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: A potent, selective, systemically active group 2 metabotropic glutamate receptor agonist possessing anticonvulsant and anxiolytic properties. J. Med. Chem. 40:1997;528-537.
    • (1997) J. Med. Chem. , vol.40 , pp. 528-537
    • Monn, J.A.1    Valli, M.J.2    Massey, S.M.3    Wright, R.A.4    Salhoff, C.R.5    Johnson, B.G.6    Howe, T.7    Alt, C.A.8    Rhodes, G.A.9    Robey, R.L.10    Griffey, K.R.11    Tizzano, J.P.12    Kallma, M.J.13    Helton, D.R.14    Schoepp, D.D.15
  • 32
    • 0031035665 scopus 로고    scopus 로고
    • Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile
    • Saugstad J.A., Kinzie J.M., Shinohara M.M., Segerson T.P., Westbrook G.L. Cloning and expression of rat metabotropic glutamate receptor 8 reveals a distinct pharmacological profile. Mol. Pharmacol. 51:1997;119-125.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 119-125
    • Saugstad, J.A.1    Kinzie, J.M.2    Shinohara, M.M.3    Segerson, T.P.4    Westbrook, G.L.5
  • 33
    • 0028874812 scopus 로고
    • Cloning and expression of a human metabotropic glutamate receptor 1α: Enhanced coupling on co-transfection with a glutamate transporter
    • Desai M.A., Burnett J.P., Mayne N.G., Schoepp D.D. Cloning and expression of a human metabotropic glutamate receptor 1α: enhanced coupling on co-transfection with a glutamate transporter. Mol. Phamacol. 48:1995;648-757.
    • (1995) Mol. Phamacol. , vol.48 , pp. 648-757
    • Desai, M.A.1    Burnett, J.P.2    Mayne, N.G.3    Schoepp, D.D.4
  • 34
    • 0029993286 scopus 로고    scopus 로고
    • Pharmacological characterization of desensitization in a human mGluR1α-expressing non-neuronal cell line co-transfected with a glutamate transporter
    • Desai M.A., Burnett J.P., Mayne N.G., Schoepp D.D. Pharmacological characterization of desensitization in a human mGluR1α-expressing non-neuronal cell line co-transfected with a glutamate transporter. Br. J. Pharmacol. 118:1996;1558-1564.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1558-1564
    • Desai, M.A.1    Burnett, J.P.2    Mayne, N.G.3    Schoepp, D.D.4
  • 35
    • 0029144223 scopus 로고
    • Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1α and mGluR5a subtypes
    • Kingston A.E., Burnett J.P., Mayne N.G., Lodge D. Pharmacological analysis of 4-carboxyphenylglycine derivatives: Comparison of effects on mGluR1α and mGluR5a subtypes. Neuropharmacology. 34:1995;887-894.
    • (1995) Neuropharmacology , vol.34 , pp. 887-894
    • Kingston, A.E.1    Burnett, J.P.2    Mayne, N.G.3    Lodge, D.4
  • 36
    • 8944234853 scopus 로고    scopus 로고
    • Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate (APDC): Identification of a potent, highly selective and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase
    • Monn J.A., Valli M.J., Johnson B.G., Salhoff C.R., Wright R.A., Howe T., Bond A., Lodge D., Spangle L.A., Paschal J.W., Campbell J.B., Griffey K., Tizzano J.P., Schoepp D.D. Synthesis of the four isomers of 4-aminopyrrolidine-2,4-dicarboxylate (APDC): identification of a potent, highly selective and systemically-active agonist for metabotropic glutamate receptors negatively coupled to adenylate cyclase. J. Med. Chem. 39:1996;2990-3000.
    • (1996) J. Med. Chem. , vol.39 , pp. 2990-3000
    • Monn, J.A.1    Valli, M.J.2    Johnson, B.G.3    Salhoff, C.R.4    Wright, R.A.5    Howe, T.6    Bond, A.7    Lodge, D.8    Spangle, L.A.9    Paschal, J.W.10    Campbell, J.B.11    Griffey, K.12    Tizzano, J.P.13    Schoepp, D.D.14
  • 38
    • 0022410222 scopus 로고
    • Synthetic oligonucleotide probes deduced from amino acid sequence data, theoretical and practical considerations
    • Lathe R. Synthetic oligonucleotide probes deduced from amino acid sequence data, theoretical and practical considerations. J. Mol. Biol. 183:1985;1-12.
    • (1985) J. Mol. Biol. , vol.183 , pp. 1-12
    • Lathe, R.1
  • 39
    • 0027263191 scopus 로고
    • High level expression of secreted proteins from cells adapted to serum free suspension culture
    • Berg D.T., McClure D.B., Grinell B.W. High level expression of secreted proteins from cells adapted to serum free suspension culture. Biotechniques. 14:1993;972-978.
    • (1993) Biotechniques , vol.14 , pp. 972-978
    • Berg, D.T.1    McClure, D.B.2    Grinell, B.W.3
  • 40
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham F.L., Van Der Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    Van Der Eb, A.J.2
  • 41
    • 0029145935 scopus 로고
    • Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability
    • Gereau R.W., Conn P.J. Roles of specific metabotropic glutamate receptor subtypes in regulation of hippocampal CA1 pyramidal cell excitability. J. Neurophysiol. 74:1995;122-129.
    • (1995) J. Neurophysiol. , vol.74 , pp. 122-129
    • Gereau, R.W.1    Conn, P.J.2
  • 42
    • 0027934857 scopus 로고
    • 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus
    • Schoepp D.D., Goldsworthy J., Johnson B.G., Salhoff C.R., Baker S.R. 3,5-Dihydroxyphenylglycine is a highly selective agonist for phosphoinositide-linked metabotropic glutamate receptors in the rat hippocampus. J. Neurochem. 63:1994;769-772.
    • (1994) J. Neurochem. , vol.63 , pp. 769-772
    • Schoepp, D.D.1    Goldsworthy, J.2    Johnson, B.G.3    Salhoff, C.R.4    Baker, S.R.5
  • 43
    • 0029131705 scopus 로고
    • New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord
    • Jane D.E., Pittaway K., Sunter D.C., Thomas N.K., Watkins J.C. New phenylglycine derivatives with potent and selective antagonist activity at presynaptic glutamate receptors in neonatal rat spinal cord. Neuropharmacology. 34:1995;851-856.
    • (1995) Neuropharmacology , vol.34 , pp. 851-856
    • Jane, D.E.1    Pittaway, K.2    Sunter, D.C.3    Thomas, N.K.4    Watkins, J.C.5
  • 44
    • 0029151828 scopus 로고
    • Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): Phenylglycine derivatives and other selective antagonists - An update
    • Roberts P.J. Pharmacological tools for the investigation of metabotropic glutamate receptors (mGluRs): phenylglycine derivatives and other selective antagonists - an update. Neuropharmacology. 34:1995;813-819.
    • (1995) Neuropharmacology , vol.34 , pp. 813-819
    • Roberts, P.J.1


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