Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

British Journal of Pharmacology

Volumn 138, Issue 6, 2003, Pages 1026-1030

  Mathiesen, Jesper Mosolff ^a,b   Svendsen, Nannette ^a   Bräuner Osborne, Hans ^b   Thomsen, Christian ^a   Ramirez, M Teresa ^a  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

35S GTP S; Allosteric; cAMP; L AP4; mGluR4; MPEP; Positive modulation; SIB 1893

Indexed keywords

2 AMINO 4 PHOSPHONOBUTYRIC ACID; 2 METHYL 6 (2 PHENYLVINYL)PYRIDINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; ALPHA CYCLOPROPYL 4 PHOSPHONOPHENYLGLYCINE; CYCLIC AMP; GLUTAMIC ACID; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; SULFUR 35; TRITIUM;

ALLOSTERISM; ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING COMPETITION; CELL ASSAY; CELL STRAIN BHK; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG INHIBITION; DRUG MECHANISM; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG SPECIFICITY; HUMAN; NONHUMAN; PARAMETER; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ALLOSTERIC REGULATION; CELL CULTURE TECHNIQUES; HUMANS; PYRIDINES; RECEPTORS, GLUTAMATE; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 0037363728     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705159     Document Type: Article

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