Probing the ligand-binding domain of the mGluR4 subtype of metabotropic glutamate receptor

Journal of Biological Chemistry

Volumn 274, Issue 47, 1999, Pages 33488-33495

  Hampson, David R ^a,c   Huang, Xi Ping ^a   Pekhletski, Roman ^a   Peltekova, Vanya ^a   Hornby, Geoffrey ^a   Thomsen, Christian ^b   Thøgersen, Henning ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b NOVO NORDISK A S   (Denmark)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINOBUTYRIC ACID DERIVATIVE; ARGININE; BACTERIAL PROTEIN; BINDING PROTEIN; GLUTAMATE RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROXYL GROUP; METABOTROPIC RECEPTOR; PHOSPHOSERINE; SERINE; THREONINE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROGEN BOND; MOLECULAR INTERACTION; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STRUCTURE; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CELL LINE; DNA PRIMERS; EPITOPES; HUMANS; IMMUNOHISTOCHEMISTRY; LIGANDS; MODELS, MOLECULAR; MOLECULAR PROBES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; RECEPTORS, METABOTROPIC GLUTAMATE; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS);

EID: 0033584994     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.47.33488     Document Type: Article

References (39)

1. Pin, J -P., and Duvoisin, R. (1995) Neuropharmacology 34, 1-26
2. Gomeza J., Mary, S., Brabet, I., Parmentier, M.-L., Restituito, S., Bockaert, J., and Pin, J.-P. (1996) Mol. Pharmacol 50, 923-930
3. Macek, T. A., Winder, D. G., Gereau, R. W., IV, Ladd, L. O., and Conn, J. P. (1996) J. Neurosci. 76, 3798-3806
4. Risso Bradley, S., Standaert, D. G., Rhodes, K. J., Rees, H. D., Testa, C. M., Levey, A. I., and Conn, P. J. (1999) J. Comp. Neurol. 407, 33-46
5. Shigemoto, R., Kinoshita, A., Wada, E., Nomura, S., Ohishi, H., Takada, M., Flor, P. J., Neki, A., Abe, T., Nakanishi, S., and Mizuno, N. (1997) J. Neurosci. 17, 7503-7522
6. Stowell, J. N., and Craig, A. M. (1999) Neuron 22, 525-536
7. Pekhletski, R., Gerlai, R., Overstreet, L., Huang, X.-P., Agoypan, N., Slater, N. T., Roder, J. C., and Hampson, D. R. (1996) J. Neurosci. 16, 6364-6373
8. Gerlai, R., Roder, J. C., and Hampson, D. R. (1998) Behav. Neurosci. 112, 1-8
9. Nicoletti, F., Bruno, V., Copani, A., Casabona, G., and Knopfel, T. (1996) Trends Neurosci. 19, 267-272
10. Thomsen, C., and Dalby, N. O. (1998) Neuropharmacology 37, 1465-1473
11. O'Hara, P. J., Sheppard, P., Thøgersen, H., Venezia, D., Haldeman, B. A., McGrane, V., Houamed, K. M., Thomsen, C., Gilbert, T. L., and Mulvihill, E. R. (1993) Neuron 11, 41-52
12. Brown, E. M., Gamba, G., Riccardi, D., Lombardi, M., Butters, R., Kifor, O., Sun, A., Hediger, M., Lytton, J., and Hebert, S. C. (1993) Nature 386, 575-580
13. Ruat, M., Molliver, M. E., Snowman, A. M., and Snyder, S. H. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 3161-3165
14. Kaupmann, K., Huggel, K., Heid, J., Flor, P. J., Bischoff, S., Mickel S. J., McMaster, G., Angst, C., Bittiger, H., Froesti, W., and Bettler, B. (1997) Nature 386, 239-246
15. Kuner, R., Kohr, G., Grunewald, S., Eisenhardt, G., Bach A., and Kornau, H.-C. (1999) Science 283, 74-77
16. Ng, G. Y. K., Clark, J., Coulombe, N., Ethier, N., Hebert, T. E., Sullivan, R., Kargman, S., Chateauneuf, A., Tsukamoto, N., McDonald T., Whiting P., Mezey, E., Johnson, M. P., Liu, Q., Kolakowski, L. F., Jr., Evans J. F., Bonner, T. I., and O'Neill, G. P. (1999) J. Biol. Chem. 274, 7607-7610
17. Matsunami, H., and Buck, L. B. (1997) Cell 90, 775-788
18. Moon, M. A., Alder, E., Lindemeier, J., Battey, J. F., Ryba, N. J. P., and Zucker, C. S. (1999) Cell 96, 541-551
19. Tones, M. A., Bendali, H., Flor, P. J., Knopfel, T., and Kühn R. (1995) Neuroreport 7, 117-120
20. Takahashi, K., Tsuchida, K., Tanabe, Y., Masu, M., and Nakanishi, S. (1993) J. Biol. Chem. 268, 19341-19345
21. Okamoto, T., Sekiyama, N., Otsu, M., Shimada, Y., Sato, A., Nakanishi, S., and Jingami, H. (1998) J. Biol. Chem. 273, 13089-13096
22. Han, G., and Hampson, D. R. (1999) J. Biol. Chem. 274, 10008-10013
23. Blundell, T. L., Sibanda, B. L., Sternberg, M. J. E., and Thornton, J. M. (1987) Nature 326, 347-352
24. Tanabe, Y., Masu, M., Ishii, T., Shigemoto, R., and Nakanishi, S. (1992) Neuron 8, 169-179
25. Eriksen, L., and Thomsen, C. (1995) Br. J. Pharmacol. 118, 3279-3287
26. Pickering, D. S., Taverna, F. A., Salter, M. W., and Hampson, D. R. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 12090-12094
27. Petralia, R. S., Wang, Y.-X., Niedzielski, A. S., and Wenthold, R. J. (1996) Neuroscience 71, 949-976
28. Conklin, B. R., Farfel, Z., Lustig, K. D., Julius, D., and Bourne, H. R. (1993) Nature 363, 274-276
29. Sack, J. S., Saper, M. A., and Quiocho, F. A. (1989) J. Mol. Biol. 206, 171-191
30. Thomsen, C., Pekhletski, R., Haldeman, B., Gilbert, T. A., O'Hara, P. J. and Hampson, D. R. (1997) Neuropharmacology 36, 21-30
31. Toms, N. J., Jane, D. E., Kemp, M. C., Bedingfield, J. S., and Roberts, P. J. (1996) Br. J. Pharmacol. 119, 851-854
32. Sutcliffe, M. J., Wo, Z. G., and Oswald, R. E. (1996) Biophys. J. 70, 1575-1589
33. Sutcliffe, M. J., Smeeton, A. H., Wo, Z. G., and Oswald, R. E. (1998) Methods Enzymol. 293, 589-619
34. Tam, R., and Saier, M. H., Jr. (1993) Microbiol. Rev. 57, 320-346
35. Chamberlain, D., O'Hara, B. P., Wilson, S. A., Pearl, L. H., and Perkins, S. J. (1997) Biochemistry 36, 8020-8029
36. Kubo, Y., Miyashita, T., and Murata, Y. (1998) Science 279, 1722-1725
37. Galvez, T., Parmentier, M.-L., Joly, C., Malitschek, B., Kaupmann K., Kuhn, R., Bittiger, H., Froestl, W., Bettler, B., and Pin, J.-P. (1999) J. Biol. Chem. 274, 13362-13369
38. Klunk, W. E., McClure, R. J., and Pettegrew, J. W. (1991) Mol. Chem. Neuropathol. 15, 51-72
39. Wroblewska, B., Wroblewski, J. T., Pschenichkin, S., Surin, A., Sullivan, S. E., and Neale, J. H. (1997) J. Neurochem. 69, 174-181