The protein structures that shape caspase activity, specificity, activation and inhibition

Biochemical Journal

Volumn 384, Issue 2, 2004, Pages 201-232

  Fuentes Prior, Pablo ^a,b   Salvesen, Guy S ^c  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b Institut Català de Ciències Cardiovasculars   (Spain)

^c BURNHAM INSTITUTE   (United States)

Author keywords

Apoptosis; Caspase; Inhibitor; Inhibitor of apoptosis protein (IAP); Protease; Zymogen

Indexed keywords

BIOCHEMISTRY; CATALYSIS; SUBSTRATES;

INITIATOR PHASES; PROTEIN STRUCTURES;

PROTEINS;

CASPASE; CASPASE 9; CASPASE INHIBITOR; CYTOKINE; ENZYME PRECURSOR; ISOENZYME; LIGASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 3; PROTEIN P35; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SERINE PROTEINASE INHIBITOR; VIRUS PROTEIN;

APOPTOSIS; CATALYSIS; CELL MEMBRANE; CRYSTAL STRUCTURE; DEVELOPMENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; IN VIVO STUDY; KNOCKOUT MOUSE; MATURATION; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MODIFICATION; PROTEIN STRUCTURE; REVIEW;

AMINO ACID SEQUENCE; ANIMALS; CASPASES; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 10644282148     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041142     Document Type: Review

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