Processed caspase-2 can induce mitochondria-mediated apoptosis independently of its enzymatic activity

EMBO Reports

Volumn 5, Issue 6, 2004, Pages 643-648

  Robertson, John D ^a,b   Gogvadze, Vladimir ^a   Kropotov, Andrey ^a   Vakifahmetoglu, Helen ^a   Zhivotovsky, Boris ^a   Orrenius, Sten ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Bcl 2; Caspase; Cytochrome c; Mitochondria

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 2; CYTOCHROME C; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CULTURE; ENZYME ACTIVITY; ENZYME RELEASE; HUMAN; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; RAT;

APOPTOSIS; APOPTOSIS INDUCING FACTOR; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; CARRIER PROTEINS; CASPASE 2; CASPASES; CYTOCHROMES C; ENZYME ACTIVATION; FLAVOPROTEINS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; MEMBRANE PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXYGEN CONSUMPTION; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 4344663051     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.embor.7400153     Document Type: Article

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