Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli

Science

Volumn 288, Issue 5467, 2000, Pages 874-877

  Yang, Yili ^a   Fang, Shengyun ^a   Jensen, Jane P ^a   Weissman, Allan M ^a   Ashwell, Jonathan D ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ETOPOSIDE; GLUCOCORTICOID; INHIBITOR OF APOPTOSIS PROTEIN; PROTEASOME; PROTEASOME INHIBITOR; UBIQUITIN PROTEIN LIGASE;

APOPTOSIS; ARTICLE; CATALYSIS; ENZYME ACTIVITY; GENETIC TRANSFECTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; THYMOCYTE;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; DEXAMETHASONE; ETOPOSIDE; HYBRIDOMAS; INHIBITOR OF APOPTOSIS PROTEINS; LIGASES; MICE; MICE, INBRED C57BL; MULTIENZYME COMPLEXES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; PROTEINS; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES; THYMUS GLAND; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

INTRACISTERNAL A-PARTICLES;

EID: 0034607655     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.288.5467.874     Document Type: Article

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