The three-dimensional structure of caspase-8: An initiator enzyme in apoptosis

Structure

Volumn 7, Issue 9, 1999, Pages 1125-1133

  Blanchard, Helen ^a   Kodandapani, Lalitha ^b   Mittl, Peer R E ^a,c   Di Marco, Stefania ^c,d   Krebs, Joseph F ^b   Wu, Joe C ^b   Tomaselli, Kevin J ^b   Grütter, Markus G ^a,c  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b PFIZER INC   (United States)

^c NOVARTIS PHARMA AG   (Switzerland)

^d IRBM   (Italy)

Author keywords

Caspases; Drug design; Inhibitor binding; Structure comparison; X ray structure

Indexed keywords

CASPASE; CASPASE INHIBITOR;

APOPTOSIS; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME ANALYSIS; ENZYME INHIBITOR COMPLEX; ENZYME KINETICS; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

EID: 0012299811     PISSN: 09692126     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-2126(99)80179-8     Document Type: Article

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