-
1
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding and activation
-
Acehan D., Jiang X., Morgan D.G., Heuser J.E., Wang X., Akey C.W. Three-dimensional structure of the apoptosome. implications for assembly, procaspase-9 binding and activation Mol. Cell. 9:2002;423-432.
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.5
Akey, C.W.6
-
2
-
-
0032575714
-
Death receptors: Signaling and modulation
-
Ashkenazi A., Dixit V.M. Death receptors. signaling and modulation Science. 281:1998;1305-1308.
-
(1998)
Science
, vol.281
, pp. 1305-1308
-
-
Ashkenazi, A.1
Dixit, V.M.2
-
4
-
-
0012299811
-
The three-dimensional structure of caspase-8: An initiator enzyme in apoptosis
-
Blanchard H., Kodandapani L., Mittl P.R.E., Di Marco S., Krebs J.F., Wu J.C., Tomaselli K.J., Grütter M.G. The three-dimensional structure of caspase-8. an initiator enzyme in apoptosis Structure. 27:1999;1125-1133.
-
(1999)
Structure
, vol.27
, pp. 1125-1133
-
-
Blanchard, H.1
Kodandapani, L.2
Mittl, P.R.E.3
Di Marco, S.4
Krebs, J.F.5
Wu, J.C.6
Tomaselli, K.J.7
Grütter, M.G.8
-
5
-
-
0035960562
-
Dimeric procaspase-3 unfolds via a four-state equilibrium process
-
Bose K., Clark A.C. Dimeric procaspase-3 unfolds via a four-state equilibrium process. Biochemistry. 40:2001;14236-14242.
-
(2001)
Biochemistry
, vol.40
, pp. 14236-14242
-
-
Bose, K.1
Clark, A.C.2
-
6
-
-
0019792891
-
Analysis of protein and peptide mixtures: Evaluation of three sodium dodecyl sulphate-polyacrylamide gel electrophoresis buffer systems
-
Bury A. Analysis of protein and peptide mixtures. Evaluation of three sodium dodecyl sulphate-polyacrylamide gel electrophoresis buffer systems J. Chromatogr. 213:1981;491-500.
-
(1981)
J. Chromatogr.
, vol.213
, pp. 491-500
-
-
Bury, A.1
-
7
-
-
0035831021
-
Structural basis of caspase-7 inhibition by XIAP
-
a
-
Chai J., Shiozaki E., Srinivasula S.M., Wu Q., Dataa P., Alnemri E.S., Shi Y. Structural basis of caspase-7 inhibition by XIAP. Cell. 104:2001;769-780. a.
-
(2001)
Cell
, vol.104
, pp. 769-780
-
-
Chai, J.1
Shiozaki, E.2
Srinivasula, S.M.3
Wu, Q.4
Dataa, P.5
Alnemri, E.S.6
Shi, Y.7
-
8
-
-
0035798361
-
Crystal structure of a procaspase-7 zymogen: Mechanisms of activation and substrate binding
-
b
-
Chai J., Wu Q., Shiozaki E., Srinivasula S.M., Alnemri E.S., Shi Y. Crystal structure of a procaspase-7 zymogen. mechanisms of activation and substrate binding Cell. 107:2001;399-407. b.
-
(2001)
Cell
, vol.107
, pp. 399-407
-
-
Chai, J.1
Wu, Q.2
Shiozaki, E.3
Srinivasula, S.M.4
Alnemri, E.S.5
Shi, Y.6
-
9
-
-
0037099678
-
C-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis
-
Chang D.W., Xing Z., Pan Y., Algeciras-Schimnich A., Barnhart B.C., Yaish-Ohad S., Peter M.E., Yang X. c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J. 21:2002;3704-3714.
-
(2002)
EMBO J.
, vol.21
, pp. 3704-3714
-
-
Chang, D.W.1
Xing, Z.2
Pan, Y.3
Algeciras-Schimnich, A.4
Barnhart, B.C.5
Yaish-Ohad, S.6
Peter, M.E.7
Yang, X.8
-
10
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun H.J., Zheng L., Ahmad M., Wang J., Speirs C.K., Siegel R.M., Dale J.K., Puck J., Davis J., Hall C.G.et al. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature. 419:2002;395-399.
-
(2002)
Nature
, vol.419
, pp. 395-399
-
-
Chun, H.J.1
Zheng, L.2
Ahmad, M.3
Wang, J.4
Speirs, C.K.5
Siegel, R.M.6
Dale, J.K.7
Puck, J.8
Davis, J.9
Hall, C.G.10
-
11
-
-
0036790423
-
Caspase-6 is the direct activator of caspase-8 in the cytochrome c- induced apoptosis pathway: Absolute requirement for removal of caspase-6 prodomain
-
Cowling V., Downward J. Caspase-6 is the direct activator of caspase-8 in the cytochrome c- induced apoptosis pathway. absolute requirement for removal of caspase-6 prodomain Cell Death Differ. 9:2002;1046-1056.
-
(2002)
Cell Death Differ.
, vol.9
, pp. 1046-1056
-
-
Cowling, V.1
Downward, J.2
-
12
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell death proteases
-
Deveraux Q., Takahashi R., Salvesen G.S., Reed J.C. X-linked IAP is a direct inhibitor of cell death proteases. Nature. 388:1997;300-304.
-
(1997)
Nature
, vol.388
, pp. 300-304
-
-
Deveraux, Q.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
13
-
-
0033215040
-
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
-
Deveraux Q.L., Leo E., Stennicke H.R., Welsh K., Salvesen G.S., Reed J.C. Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases. EMBO J. 18:1999;5242-5251.
-
(1999)
EMBO J.
, vol.18
, pp. 5242-5251
-
-
Deveraux, Q.L.1
Leo, E.2
Stennicke, H.R.3
Welsh, K.4
Salvesen, G.S.5
Reed, J.C.6
-
14
-
-
0037291890
-
Insights into the regulatory mechanism for caspase-8 activation
-
this issue,
-
Donepudi M., Mac Sweeney A., Briand C., Gruetter M.G. Insights into the regulatory mechanism for caspase-8 activation. Mol. Cell. 11:2003;543-549. this issue,
-
(2003)
Mol. Cell
, vol.11
, pp. 543-549
-
-
Donepudi, M.1
Mac Sweeney, A.2
Briand, C.3
Gruetter, M.G.4
-
15
-
-
0030008812
-
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
-
Duan H., Orth K., Chinnaiyan A.M., Poirier G.G., Froelich C.J., He W.-W., Dixit V.M. ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B. J. Biol. Chem. 271:1996;16720-16724.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 16720-16724
-
-
Duan, H.1
Orth, K.2
Chinnaiyan, A.M.3
Poirier, G.G.4
Froelich, C.J.5
He, W.-W.6
Dixit, V.M.7
-
16
-
-
0032885388
-
Mammalian caspases: Structure, activation, substrates, and functions during apoptosis
-
Earnshaw W.C., Martins L.M., Kaufmann S.H. Mammalian caspases. structure, activation, substrates, and functions during apoptosis Annu. Rev. Biochem. 68:1999;383-424.
-
(1999)
Annu. Rev. Biochem.
, vol.68
, pp. 383-424
-
-
Earnshaw, W.C.1
Martins, L.M.2
Kaufmann, S.H.3
-
17
-
-
0014109212
-
Spectroscopic determination of tryptophan and tyrosine in proteins
-
Edelhoch H. Spectroscopic determination of tryptophan and tyrosine in proteins. Biochemistry. 6:1967;1948-1954.
-
(1967)
Biochemistry
, vol.6
, pp. 1948-1954
-
-
Edelhoch, H.1
-
19
-
-
0344053451
-
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
-
Fernandes-Alnemri T., Armstrong R., Krebs J., Srinivasula S.M., Wang L., Bullrich F., Fritz L., Trapani J.A., Croce C.M., Tomaselli K.J.et al. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl. Acad. Sci. USA. 93:1996;7464-7469.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7464-7469
-
-
Fernandes-Alnemri, T.1
Armstrong, R.2
Krebs, J.3
Srinivasula, S.M.4
Wang, L.5
Bullrich, F.6
Fritz, L.7
Trapani, J.A.8
Croce, C.M.9
Tomaselli, K.J.10
-
20
-
-
0034644508
-
Insights into programmed cell death through structural biology
-
Fesik S.W. Insights into programmed cell death through structural biology. Cell. 103:2000;273-282.
-
(2000)
Cell
, vol.103
, pp. 273-282
-
-
Fesik, S.W.1
-
21
-
-
0030877440
-
CASH, a novel caspase homologue with death effector domains
-
Goltsev Y.V., Kovalenko A.V., Arnold E., Varfolomeev E.E., Brodianskii V.M., Wallach D. CASH, a novel caspase homologue with death effector domains. J. Biol. Chem. 272:1997;19641-19644.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19641-19644
-
-
Goltsev, Y.V.1
Kovalenko, A.V.2
Arnold, E.3
Varfolomeev, E.E.4
Brodianskii, V.M.5
Wallach, D.6
-
22
-
-
0030758315
-
L and initiates cell death
-
L and initiates cell death. Proc. Natl. Acad. Sci. USA. 94:1997;11333-11338.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11333-11338
-
-
Han, D.K.M.1
Chaudhary, P.M.2
Wright, M.E.3
Friedman, C.4
Trask, B.J.5
Riedel, R.T.6
Baskin, D.G.7
Schwartz, S.M.8
Hood, L.9
-
23
-
-
0030961084
-
CLARP, a death effector domain containing protein interacts with caspase-8 and regulates apoptosis
-
Inohara N., Koseki T., Hu Y., Chen S., Nunez G. CLARP, a death effector domain containing protein interacts with caspase-8 and regulates apoptosis. Proc. Natl. Acad. Sci. USA. 94:1997;10717-10722.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10717-10722
-
-
Inohara, N.1
Koseki, T.2
Hu, Y.3
Chen, S.4
Nunez, G.5
-
24
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
25
-
-
0032555697
-
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
-
Li H., Zhu H., Xu C.J., Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell. 94:1998;491-501.
-
(1998)
Cell
, vol.94
, pp. 491-501
-
-
Li, H.1
Zhu, H.2
Xu, C.J.3
Yuan, J.4
-
26
-
-
0032555716
-
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
-
Luo X., Budihardjo I., Zou H., Slaughter C., Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell. 94:1998;481-490.
-
(1998)
Cell
, vol.94
, pp. 481-490
-
-
Luo, X.1
Budihardjo, I.2
Zou, H.3
Slaughter, C.4
Wang, X.5
-
27
-
-
0036904978
-
Conditional cell ablation by tight control of caspase-3 dimerization in transgenic mice
-
Mallet V.O., Mitchell C., Guidotti J.E., Jaffray P., Fabre M., Spencer D., Arnoult D., Kahn A., Gilgenkrantz H. Conditional cell ablation by tight control of caspase-3 dimerization in transgenic mice. Nat. Biotechnol. 20:2002;1234-1239.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1234-1239
-
-
Mallet, V.O.1
Mitchell, C.2
Guidotti, J.E.3
Jaffray, P.4
Fabre, M.5
Spencer, D.6
Arnoult, D.7
Kahn, A.8
Gilgenkrantz, H.9
-
28
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
-
Martinon F., Burns K., Tschopp J. The inflammasome. a molecular platform triggering activation of inflammatory caspases and processing of proIL-β Mol. Cell. 10:2002;417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
29
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O., Thome M., Schneider P., Holler N., Tschopp J., Nicholson D.W., Briand C., Grutter M.G. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J. Biol. Chem. 277:2002;45162-45171.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
Briand, C.7
Grutter, M.G.8
-
30
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
Muzio M., Chinnaiyan A.M., Kischkel F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R.et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:1996;817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
31
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
Muzio M., Stockwell B.R., Stennicke H.R., Salvesen G.S., Dixit V.M. An induced proximity model for caspase-8 activation. J. Biol. Chem. 273:1998;2926-2930.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
32
-
-
0035807966
-
Dimer formation drives the activation of the cell death protease caspase 9
-
Renatus M., Stennicke H.R., Scott F.L., Liddington R.C., Salvesen G.S. Dimer formation drives the activation of the cell death protease caspase 9. Proc. Natl. Acad. Sci. USA. 98:2001;14250-14255.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14250-14255
-
-
Renatus, M.1
Stennicke, H.R.2
Scott, F.L.3
Liddington, R.C.4
Salvesen, G.S.5
-
33
-
-
0035909889
-
Structural basis for the activation of human procaspase-7
-
a
-
Riedl S.J., Fuentes-Prior P., Renatus M., Kairies N., Krapp R., Huber R., Salvesen G.S., Bode W. Structural basis for the activation of human procaspase-7. Proc. Natl. Acad. Sci. USA. 98:2001;14790-14795. a.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 14790-14795
-
-
Riedl, S.J.1
Fuentes-Prior, P.2
Renatus, M.3
Kairies, N.4
Krapp, R.5
Huber, R.6
Salvesen, G.S.7
Bode, W.8
-
34
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
b
-
Riedl S.J., Renatus M., Schwarzenbacher R., Zhou Q., Sun S., Fesik S.W., Liddington R.C., Salvesen G.S. Structural basis for the inhibition of caspase-3 by XIAP. Cell. 104:2001;791-800. b.
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, S.5
Fesik, S.W.6
Liddington, R.C.7
Salvesen, G.S.8
-
35
-
-
0033573020
-
Caspase-9 and APAF-1 form an active holoenzyme
-
Rodriguez J., Lazebnik Y. Caspase-9 and APAF-1 form an active holoenzyme. Genes Dev. 13:1999;3179-3184.
-
(1999)
Genes Dev.
, vol.13
, pp. 3179-3184
-
-
Rodriguez, J.1
Lazebnik, Y.2
-
36
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen G.S., Dixit V.M. Caspases. intracellular signaling by proteolysis Cell. 91:1997;443-446.
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
37
-
-
0033613143
-
Caspase activation: The induced-proximity model
-
Salvesen G.S., Dixit V.M. Caspase activation. the induced-proximity model Proc. Natl. Acad. Sci. USA. 96:1999;10964-10967.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10964-10967
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
38
-
-
0031004379
-
Dimerization and activation of the herpes simplex virus type 1 protease
-
Schmidt U., Darke P.L. Dimerization and activation of the herpes simplex virus type 1 protease. J. Biol. Chem. 272:1997;7732-7735.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 7732-7735
-
-
Schmidt, U.1
Darke, P.L.2
-
39
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
Shi Y. Mechanisms of caspase activation and inhibition during apoptosis. Mol. Cell. 9:2002;459-470.
-
(2002)
Mol. Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
40
-
-
0030746740
-
Casper is a FADD- and caspase-related inducer of apoptosis
-
Shu H.B., Halpin D.R., Goeddel D.V. Casper is a FADD- and caspase-related inducer of apoptosis. Immunity. 6:1997;751-763.
-
(1997)
Immunity
, vol.6
, pp. 751-763
-
-
Shu, H.B.1
Halpin, D.R.2
Goeddel, D.V.3
-
41
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee E.A., Harte M.T., Kluck R.M., Wolf B.B., Casiano C.A., Newmeyer D.D., Wang H.G., Reed J.C., Nicholson D.W., Alnemri E.S.et al. Ordering the cytochrome c-initiated caspase cascade. hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner J. Cell Biol. 144:1999;281-292.
-
(1999)
J. Cell Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
-
42
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
Srinivasula S.M., Hegde R., Saleh A., Datta P., Shiozaki E., Chai J., Lee R.A., Robbins P.D., Fernandes-Alnemri T., Shi Y., Alnemri E.S. A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis. Nature. 410:2001;112-116.
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.S.11
-
43
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
Srinivasula S.M., Poyet J.L., Razmara M., Datta P., Zhang Z., Alnemri E.S. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J. Biol. Chem. 277:2002;21119-21122.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
44
-
-
0032847318
-
Caspases: Preparation and characterization
-
Stennicke H.R., Salvesen G.S. Caspases. preparation and characterization Methods. 17:1999;313-319.
-
(1999)
Methods
, vol.17
, pp. 313-319
-
-
Stennicke, H.R.1
Salvesen, G.S.2
-
45
-
-
0033605722
-
Caspase-9 can be activated without proteolytic processing
-
Stennicke H.R., Deveraux Q.L., Humke E.W., Reed J.C., Dixit V.M., Salvesen G.S. Caspase-9 can be activated without proteolytic processing. J. Biol. Chem. 274:1999;8359-8362.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8359-8362
-
-
Stennicke, H.R.1
Deveraux, Q.L.2
Humke, E.W.3
Reed, J.C.4
Dixit, V.M.5
Salvesen, G.S.6
-
46
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
Stennicke H.R., Jurgensmeier J.M., Shin H., Deveraux Q., Wolf B.B., Yang X., Zhou Q., Ellerby H.M., Ellerby L.M., Bredesen D.et al. Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem. 273:1998;27084-27090.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
Jurgensmeier, J.M.2
Shin, H.3
Deveraux, Q.4
Wolf, B.B.5
Yang, X.6
Zhou, Q.7
Ellerby, H.M.8
Ellerby, L.M.9
Bredesen, D.10
-
47
-
-
0035793580
-
Lysosomal protease pathways to apoptosis: Cleavage of bid, not pro-caspases, is the most likely route
-
Stoka V., Turk B., Schendel S.L., Kim T.H., Cirman T., Snipas S.J., Ellerby L.M., Bredesen D., Freeze H., Abrahamson M.et al. Lysosomal protease pathways to apoptosis. cleavage of bid, not pro-caspases, is the most likely route J. Biol. Chem. 276:2001;3149-3157.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 3149-3157
-
-
Stoka, V.1
Turk, B.2
Schendel, S.L.3
Kim, T.H.4
Cirman, T.5
Snipas, S.J.6
Ellerby, L.M.7
Bredesen, D.8
Freeze, H.9
Abrahamson, M.10
-
48
-
-
0034721940
-
NMR structure and mutagenesis of the third BIR domain of the inhibitor of apoptosis protein XIAP
-
Sun C., Cai M., Meadows R.P., Xu N., Gunasekera A.H., Herrmann J., Wu J.C., Fesik S.W. NMR structure and mutagenesis of the third BIR domain of the inhibitor of apoptosis protein XIAP. J. Biol. Chem. 275:2000;33777-33781.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 33777-33781
-
-
Sun, C.1
Cai, M.2
Meadows, R.P.3
Xu, N.4
Gunasekera, A.H.5
Herrmann, J.6
Wu, J.C.7
Fesik, S.W.8
-
49
-
-
0030727712
-
Granule-mediated killing: Pathways for granzyme B-initiated apoptosis
-
Talanian R.V., Yang X., Turbov J., Seth P., Ghayur T., Casiano C.A., Orth K., Froelich C.J. Granule-mediated killing. pathways for granzyme B-initiated apoptosis J. Exp. Med. 186:1997;1323-1331.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1323-1331
-
-
Talanian, R.V.1
Yang, X.2
Turbov, J.3
Seth, P.4
Ghayur, T.5
Casiano, C.A.6
Orth, K.7
Froelich, C.J.8
-
50
-
-
0028990125
-
Yama/CPP32-β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32-β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
51
-
-
0032575750
-
Caspases: Enemies within
-
Thornberry N.A., Lazebnik Y. Caspases. enemies within Science. 281:1998;1312-1316.
-
(1998)
Science
, vol.281
, pp. 1312-1316
-
-
Thornberry, N.A.1
Lazebnik, Y.2
-
52
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M., Houtzager V.M., Nordstrom P.A., Roy S., Vaillancourt J.P.et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272:1997;17907-17911.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
Houtzager, V.M.7
Nordstrom, P.A.8
Roy, S.9
Vaillancourt, J.P.10
-
54
-
-
0034077189
-
Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies
-
Wang J., Lenardo M.J. Roles of caspases in apoptosis, development, and cytokine maturation revealed by homozygous gene deficiencies. J. Cell Sci. 113:2000;753-757.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 753-757
-
-
Wang, J.1
Lenardo, M.J.2
-
55
-
-
0006871386
-
The atomic resolution structure of human caspase-8, a key activator of apoptosis
-
Watt W., Koeplinger K.A., Mildner A.M., Heinrikson R.L., Tomasselli G., Watenpaugh K.D. The atomic resolution structure of human caspase-8, a key activator of apoptosis. Structure. 27:1999;1135-1143.
-
(1999)
Structure
, vol.27
, pp. 1135-1143
-
-
Watt, W.1
Koeplinger, K.A.2
Mildner, A.M.3
Heinrikson, R.L.4
Tomasselli, G.5
Watenpaugh, K.D.6
-
56
-
-
0030970351
-
Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity
-
Zhou Q., Salvesen G.S. Activation of pro-caspase-7 by serine proteases includes a non-canonical specificity. Biochem. J. 324:1997;361-364.
-
(1997)
Biochem. J.
, vol.324
, pp. 361-364
-
-
Zhou, Q.1
Salvesen, G.S.2
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