Activation of caspases-8 and -10 by FLIPL

Biochemical Journal

Volumn 382, Issue 2, 2004, Pages 651-657

  Boatright, Kelly M ^a,b   Deis, Cristina ^a   Denault, Jean Bernard ^a   Sutherlin, Daniel P ^c   Salvesen, Guy S ^a,b  

^a BURNHAM INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

Author keywords

Apoptosis; Caspase 8; FLIPL (FLICE like inhibitory protein); Protease; Zymogen

Indexed keywords

ACTIVATION ANALYSIS; CATALYSIS; DIMERS; ENZYME INHIBITION; MONOMERS;

CASPASE ACTIVATION; FAS-ASSOCIATED DEATH DOMAIN PROTEIN (FADD); ZYMOGENS;

PROTEINS;

CASPASE 10; CASPASE 8; ENZYME PRECURSOR; FLICE INHIBITORY PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; CONCENTRATION RESPONSE; DIMERIZATION; ENZYME ACTIVATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION;

CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 10; CASPASE 8; CASPASES; CELL LINE, TUMOR; DIMERIZATION; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; HYDROLYSIS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS;

EID: 4544288868     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040809     Document Type: Article

References (31)

1. Chang, D. W., Xing, Z., Pan, Y., Algeciras-Schimnich, A., Barnhart, B. C., Yaish-Ohad, S., Peter, M. E. and Yang, X. (2002) c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediaied apopiosis. EMBO J. 21, 3704-3714
2. Micheau, O., Thome, M., Schneider, P., Holler, N., Tschopp, J., Nicholson, D. W., Briand, C. and Grutter, M. G. (2002) The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J. Biol. Chem. 277, 45162-45171
3. Alnemri, E. S., Livingston, D. J., Nicholson, D. W., Salvesen, G., Thornberry, N. A., Wong, W. W. and Yuan, J. (1996) Human ICE/CED-3 profease nomenclature. Cell 87, 171
4. Boatright, K. M., Renatus, M., Scott, F. L., Sperandio, S., Shin, H., Pedersen, I., Ricci, J.-E., Edris, W. A., Sutherlin, D. P., Green, D. R. and Salvesen, G. S. (2003) A unified model for apical caspase activation. Mol. Cell 11, 529-541
5. Stennicke, H. R. and Salvesen, G. S. (1999) Caspases: preparation and characterization. Methods 17, 313-319
6. Deveraux, Q., Takahashi, R., Salvesen, G. S. and Reed, J. C. (1997) X-linked IAP is a direct inhibitor of cell death proteases. Nature (London) 388, 300-304
7. Simanis, V. and Lane, D. P. (1985) An immunoaffinity purification procedure for SV40 large T antigen. Virology 144, 88-100
8. Stennicke, H. R. and Salvesen, G. S. (2000) Caspase assays. Methods Enzymol 322, 91-100
9. Schmidt, U. and Darke, P. L. (1997) Dimerization and activation of the herpes simplex virus type 1 protease. J. Biol. Chem. 272, 7732-7735
10. Donepudi, M., MacSweeney, A., Briand, C. and Gruetter, M. G. (2003) Insights into the regulatory mechanism for caspase-8 activation. Mol. Cell 11, 543-549
11. Kataoka, T. and Tschopp, J. (2004) N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway Mol. Cell. Biol. 24, 2627-2636
12. Scaffidi, C., Schmitz, I., Krammer, P. H. and Peter, M. E. (1999) The role of c-FLIP in modulation of CD95-induced apoptosis. J. Biol. Chem. 274, 1541-1548
13. Shu, H. B., Halpin, D. R. and Goeddel, D. V. (1997) Casper is a FADD- and caspase-related inducer of apoptosis. Immunity 6, 751-763
14. Ashkenazi, A. and Dixit, V. M. (1998) Death receptors: signaling and modulation. Science 281, 1305-1308
15. Salvesen, G. S. and Dixit, V. M. (1999) Caspase activation: The induced-proximity model. Proc. Natl. Acad. Sci. U.S.A. 96, 10964-10967
16. Boatright, K. M. and Salvesen, G. S. (2003) Mechanisms of caspase activation. Curr. Opin. Cell Biol. 15, 725-731
17. Chang, D. W., Xing, Z., Capacio, V. L., Peter, M. E. and Yang, X. (2003) Inter-dimer processing mechanism of procaspase-8 activation. EMBO J. 22, 4132-4142
18. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J.-L., Schroter, M., Burns, K., Mattmann, C. et al. (1997) Inhibition of death receptors signals by cellular FLIP. Nature (London) 388, 190-195
19. Hu, S., Vincenz, C., Ni, J., Gentz, R. and Dixit, V. M. (1997) I-FLICE, a novel inhibitor of tumor necrosis factor recepior-1- and CD-95-induced apoptosis. J. Biol. Chem. 272, 17255-17257
20. Rasper, D. M., Vaillancourt, J. P., Hadano, S., Houtzager, V. M., Seiden, I., Keen, S. L., Tawa, P., Xanthoudakis, S., Nasir, J., Martindale, D. et al. (1998) Cell death attenuation by 'Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex. Cell Death Differ. 5, 271-288
21. Srinivasula, S. M., Ahmad, M., Ottile, S., Bullrich, F., Banks, S., Wang, Y., Fernandes-Alnemri, T., Croce, C. M., Litwack, G., Tomaselli, K. J. et al. (1997) FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis. J. Biol. Chem. 272, 18542-18545
22. Thome, M., Schneider, P., Hofmann, K., Fickenscher, H., Meinl, E., Neipel, F., Mattmann, C., Burns, K., Bodmer, J.-L., Schroter, M. et al. (1997) Viral FLICE-inhibilory proteins (FLIPs) prevents apoptosis induced by death receptors. Nature (London) 386, 517-521
23. Goltsev, Y. V., Kovalenko, A. V., Arnold, E., Varfolomeev, E. E., Brodianskii, V. M. and Wallach, D. (1997) CASH, a novel caspase homologue with death effector domains. J. Biol. Chem. 272, 19641-19644
24. L and initiates cell death. Proc. Natl. Acad. Sci. U.S.A. 94, 11333-11338
25. Inohara, N., Koseki, T., Hu, Y., Chen, S. and Nunez, G. (1997) CLARP, a death effector domain containing protein interacts with caspase-8 and regulates apoptosis. Proc. Natl. Acad. Sci. U.S.A. 94, 10717-10722
26. Riedl, S. J., Fuentes-Prior, P., Renatus, M., Kairies, N., Krapp, R., Huber, R., Salvesen, G. S. and Bode, W. (2001) Structural basis for the activation of human procaspase-7. Proc. Natl. Acad. Sci. U.S.A. 98, 14790-14795
27. Chai, J., Wu, Q., Shiozaki, E., Srinivasula, S. M., Alnemri, E. S. and Shi, Y. (2001) Crystal structure of a procaspase-7 zymogen. Mechanisms of activation and substrate binding. Cell 107, 399-407
28. Renatus, M., Stennicke, H. R., Scott, F. L., Liddington, R. C. and Salvesen, G. S. (2001) Dimer formation drives the activation of the cell death protease caspase 9. Proc. Natl. Acad. Sci. U.S.A. 98, 14250-14255
29. Seiki, M., Mori, H., Kajita, M., Uekita, T. and Itoh, Y. (2003) Membrane-type 1 matrix metalloproteinase and cell migration. Biochem. Soc. Symp. 70, 253-262
30. Howard, E. W., Bullen, E. C. and Banda, M. J. (1991) Regulation of the autoactivation of human 72-kDa progelatinase by tissue inhibitor of metalloproteinases-2. J. Biol. Chem. 266, 13064-13069
31. Chun, H. J., Zheng, L., Ahmad, M., Wang, J., Speirs, C. K., Siegel, R. M., Dale, J. K., Puck, J., Davis, J., Hall, C. G. et al. (2002) Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature (London) 419, 395-399