Involvement of receptor-interacting protein 2 in innate and adaptive immune responses

Nature

Volumn 416, Issue 6877, 2002, Pages 190-194

  Chin, Arnold I ^a   Dempsey, Paul W ^b   Bruhn, Kevin ^b   Miller, Jeff F ^b   Xu, Yang ^a,c   Cheng, Genhong ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SECTION OF MOLECULAR BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; INTERFERONS; MICROORGANISMS; PATHOLOGY;

KILLER CELLS;

IMMUNOLOGY;

CD4 ANTIGEN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G1; INTERLEUKIN 12; INTERLEUKIN 18; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN; RECEPTOR; T LYMPHOCYTE RECEPTOR; TOLL LIKE RECEPTOR 4;

GENE; IMMUNE RESPONSE; IMMUNITY; PROTEIN;

ANIMAL MODEL; ARTICLE; CYTOKINE PRODUCTION; EMBRYO; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE DISRUPTION; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOBLOTTING; IMMUNOPRECIPITATION; INFECTION; LISTERIA MONOCYTOGENES; MACROPHAGE; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CARRIER PROTEINS; CELL LINE; DROSOPHILA PROTEINS; GENE DELETION; HUMANS; IMMUNITY, NATURAL; IMMUNOGLOBULIN CLASS SWITCHING; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-18; KILLER CELLS, NATURAL; LIPOPOLYSACCHARIDES; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; LYMPHOCYTE ACTIVATION; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASE 2; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RECEPTORS, CELL SURFACE; SHOCK, SEPTIC; TH1 CELLS; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS;

ANIMALIA; LISTERIA; LISTERIA MONOCYTOGENES;

EID: 0037075549     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/416190a     Document Type: Article

References (22)

1. Innate immune recognition and control of adaptive immune responses
2. RIP2 is a novel NF-κB-activating and cell death-inducing kinase
3. RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis
4. Identification of CARDIAK, a RIP-like kinase that associates with caspase-1
5. Adjuvant-guided type-1 and type-2 immunity: Infectious/noninfectious dichotomy defines the class of response
6. Lymphokine control of in vivo immunoglobulin isotype selection
7. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
8. Lymphocyte responses and cytokines
9. Induction of interferon-gamma production in Th1 CD4 + T cells: Evidence for two distinct pathways for promoter activation
10. Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
11. Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice
12. Interleukin-12: A proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity
13. Impaired macrophage listericidal and cytokine activities are responsible for the rapid death of Listeria monocytogenes-infected IFNγ receptor-deficient mice
14. Disruption of the cellular inflammatory response to Listeria monocytogenes infection in mice with disruptions in targeted genes
15. Human Nod1 confers responsiveness to bacterial lipopolysaccharides
16. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
17. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
18. An induced proximity model for NF-κB activation in the Nod1/RICK and RIP signaling pathways
19. Nod2, a Nod1/Apaf-I family member that is restricted to monocytes and activates NF-κB
20. CARD4/Nod1 mediates NF-κB and JNK activation by invasive Shigella flexneri
21. Constructing polycompetitor cDNAs for quantitative PCR
22. Induction of the Ly-6A/E gene by interferon alpha/beta and gamma requires a DNA element to which a tyrosine-phosphorylated 91-kDa protein binds