Identification of a basic surface area of the FADD death effector domain critical for apoptotic signaling

FEBS Letters

Volumn 527, Issue 1-3, 2002, Pages 250-254

  Kaufmann, Markus ^a   Bozic, Damir ^a   Briand, Christophe ^a   Bodmer, Jean Luc ^b,d   Zerbe, Oliver ^c   Kohl, Andreas ^a   Tschopp, Jürg ^b   Grütter, Markus G ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c ETH ZURICH   (Switzerland)

^d SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Caspase 8; Cellular FLICE inhibitor protein; Death effector domain; Death inducing signaling complex; Fas associated death domain; Homotypic interaction

Indexed keywords

AMINO ACID; CASPASE 8; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN; MUTANT PROTEIN; PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DEATH; ENZYMATIC ASSAY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; UNINDEXED SEQUENCE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; APOPTOSIS; BINDING SITES; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 3; CASPASES; CELLS, CULTURED; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION;

EID: 0037063338     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(02)03146-0     Document Type: Article

References (34)

1. Heemels M.T. Nature. 407:2000;769-816.
2. Zornig M., Hueber A., Baum W., Evan G. Biochim. Biophys. Acta. 1551:2001;F1-F37.
3. Roshal M., Zhu Y., Planelles V. Apoptosis. 6:2001;103-116.
4. Chinnaiyan A.M., Tepper C.G., Seldin M.F., O'Rourke K., Kischkel F.C., Hellbardt S., Krammer P.H., Peter M.E., Dixit V.M. J. Biol. Chem. 271:1996;4961-4965.
5. Bodmer J.L., Schneider P., Tschopp J. Trends Biochem. Sci. 27:2002;19-26.
6. Walczak H., Sprick M.R. Trends Biochem. Sci. 26:2001;452-453.
7. Rasper D.M., Vaillancourt J.P., Hadano S., Houtzager V.M., Seiden I., Keen S.L., Tawa P., Xanthoudakis S., Nasir J., Martindale D., Koop B.F., Peterson E.P., Thornberry N.A., Huang J., MacPherson D.P., Black S.C., Hornung F., Lenardo M.J., Hayden M.R., Roy S., Nicholson D.W. Cell Death Differ. 5:1998;271-288.
8. Tschopp J., Irmler M., Thome M. Curr. Opin. Immunol. 10:1998;552-558.
9. Acehan D., Jiang X., Morgan D.G., Heuser J.E., Wang X., Akey C.W. Mol. Cell. 9:2002;423-432.
10. Weber C.H., Vincenz C. Trends Biochem. Sci. 26:2001;475-481.
11. Fairbrother W.J., Gordon N.C., Humke E.W., O'Rourke K.M., Starovasnik M.A., Yin J.P., Dixit V.M. Protein Sci. 10:2001;1911-1918.
12. Sukits S.F., Lin L.L., Hsu S., Malakian K., Powers R., Xu G.Y. J. Mol. Biol. 310:2001;895-906.
13. Qin H., Srinivasula S.M., Wu G., Fernandes-Alnemri T., Alnemri E.S., Shi Y. Nature. 399:1999;549-557.
14. Xiao T., Towb P., Wasserman S.A., Sprang S.R. Cell. 99:1999;545-555.
15. Eberstadt M., Huang B., Chen Z., Meadows R.P., Ng S.C., Zheng L., Lenardo M.J., Fesik S.W. Nature. 392:1998;941-945.
16. Garvey T.L., Bertin J., Siegel R.M., Wang G.H., Lenardo M.J., Cohen J.I. J. Virol. 76:2002;697-706.
17. Thompson J.D., Higgins D.G., Gibson T.J. Nucleic Acids Res. 22:1994;4673-4680.
18. Sali A., Blundell T.L. J. Mol. Biol. 234:1993;779-815.
19. Laskowski R.A., MacArthur M.W., Moss D.S., Thornton J.M. J. Appl. Crystallogr. 26:1993;283-291.
20. Jones T.A., Zou J.Y., Cowan S.W., Kjeldgaard M. Acta Crystallogr. A47:1991;110-119.
21. Nicholls A., Sharp K.A., Honig B. Proteins. 11:1991;281-296.
22. Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V., Bodmer J.L., Schroter M., Burns K., Mattmann C., Rimoldi D., French L.E., Tschopp J. Nature. 388:1997;190-195.
23. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989), Molecular Cloning, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
24. Bodmer J.L., Holler N., Reynard S., Vinciguerra P., Schneider P., Juo P., Blenis J., Tschopp J. Nat. Cell Biol. 2:2000;241-243.
25. Bodmer J.L., Burns K., Schneider P., Hofmann K., Steiner V., Thome M., Bornand T., Hahne M., Schroter M., Becker K., Wilson A., French L.E., Browning J.L., MacDonald H.R., Tschopp J. Immunity. 6:1997;79-88.
26. Bodenhausen G., Ruben D.J. Chem. Phys. Lett. 69:1980;185-189.
27. Palmer A.G., Cavanagh J., Wright P.E., Rance M. J. Magn. Reson. 93:1991;151-170.
28. Kay L.E., Keifer P., Saarien T. J. Am. Chem. Soc. 114:1992;10663-10665.
29. Cavanagh, J., Fairbrother, W.J., Palmer, A.G. and Skelton, N.J. (1996), Protein NMR Spectroscopy: Principles and Practice, Academic Press, London.
30. Live D.H., Davis D.G., Agosta W.C., Cowburn D. J. Am. Chem. Soc. 106:1984;6104.
31. Wishart D.S., Sykes B.D., Richards F.M. J. Mol. Biol. 222:1991;311-333.
32. Weber C.H., Vincenz C. FEBS Lett. 492:2001;171-176.
33. Park W.S., Lee J.H., Shin M.S., Park J.Y., Kim H.S., Kim Y.S., Lee S.N., Xiao W., Park C.H., Lee S.H., Yoo N.J., Lee J.Y. Oncogene. 21:2002;2919-2925.
34. Bundi A., Wüthrich K. Biopolymers. 18:1979;285-297.