Comprehensive studies on subcellular localizations and cell death-inducing activities of eight GFP-tagged apoptosis-related caspases

Experimental Cell Research

Volumn 264, Issue 2, 2001, Pages 315-325

  Shikama, Yoshiaki ^a   Mami, U ^a   Miyashita, Toshiyuki ^a   Yamada, Masao ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Apoptosis; Caspase; Confocal microscopy; Green fluorescent protein; Subcellular localization

Indexed keywords

CASPASE; GREEN FLUORESCENT PROTEIN;

APOPTOSIS; ARTICLE; CELL DEATH; CELLULAR DISTRIBUTION; CLASSIFICATION; CONFOCAL MICROSCOPY; CYTOPLASM; ENZYME ACTIVITY; ENZYME LOCALIZATION; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035298087     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.2000.5153     Document Type: Article

References (29)

1. Human ICE/CED-3 protease nomenclature
2. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
3. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
4. Differential requirement for caspase 9 in apoptotic pathways in vivo
5. Apoptosis: Cell death defined by caspase activation
6. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
7. Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation
8. Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
9. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
10. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
11. Prodomain-dependent nuclear localization of the caspase-2 (Nedd2) precursor. A novel function for a caspase prodomain
12. Mitochondrial release of caspase-2 and -9 during the apoptotic process
13. Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis
14. A simple and rapid method for generating a deletion by PCR
15. Dentatorubral pallidoluysian atrophy (DR-PLA) protein is cleaved by caspase-3 during apoptosis
16. The transcriptional role of PML and the nuclear body
17. Identification of the cytolinker plectin as a major early in vivo substrate for caspase 8 during CD95- and tumor necrosis factor receptor-mediated apoptosis
18. Kinesin and dynein superfamily proteins and the mechanism of organelle transport
19. Caspase structure, proteolytic substrates, and function during apoptotic cell death
20. Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10
21. Death-effector filaments: Novel cytoplasmic structures that recruit caspases and trigger apoptosis
22. EIB 19K inhibits Fas-mediated apoptosis through FADD-dependent sequestration of FLICE
23. Requirement of cooperative functions of two repeated death effector domains in caspase-8 and in MC159 for induction and inhibition of apoptosis, respectively
24. Caspase recruitment domain (CARD)-dependent cytoplasmic filaments mediate bcl10-induced NF-kappaB activation
25. Autoproteolytic activation of pro-caspases by oligomerization
26. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
27. PML is essential for multiple apoptotic pathways
28. Activation of membrane-associated procaspase-3 is regulated by Bcl-2
29. Caspases: Their intracellular localization and translocation during apoptosis