-
1
-
-
0009530192
-
Human ICE/CED-3 protease nomenclature
-
1 Alnemri, E. S., Livingston, D. J., Nicholson, D. W., Salvesen, G., Thornberry, N. A., Wong, W. W. and Yuan, J. (1996) Human ICE/CED-3 protease nomenclature. Cell 87, 171
-
(1996)
Cell
, vol.87
, pp. 171
-
-
Alnemri, E.S.1
Livingston, D.J.2
Nicholson, D.W.3
Salvesen, G.4
Thornberry, N.A.5
Wong, W.W.6
Yuan, J.7
-
2
-
-
0030948457
-
Substrate specilicities of caspase family proteases
-
2 Talanian, R. V., Quinlan, C., Trautz, S., Hackett, M., Mankovich, J. A., Banach, D., Ghayur, T., Brady, K. and Wong, W. W. (1997) Substrate specilicities of caspase family proteases. J. Biol. Chem. 272, 9677-9682
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9677-9682
-
-
Talanian, R.V.1
Quinlan, C.2
Trautz, S.3
Hackett, M.4
Mankovich, J.A.5
Banach, D.6
Ghayur, T.7
Brady, K.8
Wong, W.W.9
-
3
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
3 Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P. Chapman, K. T. and Nicholson, D. W. (1997) A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
Houtzager, V.M.7
Nordstrom, P.A.8
Roy, S.9
Vaillancourt, J.P.10
Chapman, K.T.11
Nicholson, D.W.12
-
4
-
-
0030931876
-
Caspases: The executioners of apoptosis
-
4 Cohen, G M. (1997) Caspases: the executioners of apoptosis. Biochem. J. 326, 1-16
-
(1997)
Biochem. J.
, vol.326
, pp. 1-16
-
-
Cohen, G.M.1
-
6
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
6 Salvesen, G. S. and Dixit, V. M. (1997) Caspases: intracellular signaling by proteolysis. Cell 91, 443-446
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
7
-
-
15844412409
-
FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
-
7 Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R. et al. (1996) FLICE, a novel FADD homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell 85, 817-827
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
8
-
-
0030925774
-
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC)
-
8 Medema, J. P., Scaffidi, C., Kischkel, F. C., Shevchenko, A., Mann, M., Krammer, P. H. and Peter, M. E. (1997) FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16, 2794-2804
-
(1997)
EMBO J.
, vol.16
, pp. 2794-2804
-
-
Medema, J.P.1
Scaffidi, C.2
Kischkel, F.C.3
Shevchenko, A.4
Mann, M.5
Krammer, P.H.6
Peter, M.E.7
-
9
-
-
0032548842
-
Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal
-
9 Martin, D. A., Siegel, R. M., Zheng, L. and Lenardo, M. J. (1998) Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J. Biol. Chem. 273, 4345-4349
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4345-4349
-
-
Martin, D.A.1
Siegel, R.M.2
Zheng, L.3
Lenardo, M.J.4
-
10
-
-
0031615875
-
Autoproteolytic activation of procaspases by oligomerization
-
10 Yang, X., Chang, H. Y. and Baltimore, D. (1998) Autoproteolytic activation of procaspases by oligomerization Mol. Cell. 1, 319-325
-
(1998)
Mol. Cell.
, vol.1
, pp. 319-325
-
-
Yang, X.1
Chang, H.Y.2
Baltimore, D.3
-
11
-
-
0032579490
-
An induced proximity model for caspase-8 activation
-
11 Muzio, M., Stockwell, B. R., Stennicke, H. R., Salvesen, G. S. and Dixit, V. M. (1998) An induced proximity model for caspase-8 activation. J. Biol. Chem. 273, 2926-2930
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 2926-2930
-
-
Muzio, M.1
Stockwell, B.R.2
Stennicke, H.R.3
Salvesen, G.S.4
Dixit, V.M.5
-
12
-
-
0032544268
-
Apoptotic pathways: The roads to ruin
-
12 Green, D. R. (1998) Apoptotic pathways: the roads to ruin. Cell 94, 695-698
-
(1998)
Cell
, vol.94
, pp. 695-698
-
-
Green, D.R.1
-
13
-
-
0033580926
-
Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
-
13 Saleh, A., Srinivasula, S. M., Acharya, S., Fishel, R. and Alnemri, E. S. (1999) Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J. Biol. Chem. 274, 17941-17945
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17941-17945
-
-
Saleh, A.1
Srinivasula, S.M.2
Acharya, S.3
Fishel, R.4
Alnemri, E.S.5
-
14
-
-
0029890823
-
Apopain/CPP32 cleaves proteins that are essential for cellular repair: A fundamental principle of apoptotic death
-
14 Casciola-Rosen, L., Nicholson, D. W., Chong, T., Rowan, K. R., Thornberry, N. A., Miller, D. K. and Rosen, A. (1996) Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med. 183, 1957-1964
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1957-1964
-
-
Casciola-Rosen, L.1
Nicholson, D.W.2
Chong, T.3
Rowan, K.R.4
Thornberry, N.A.5
Miller, D.K.6
Rosen, A.7
-
15
-
-
0030820875
-
Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
-
15 Kothakota, S., Azuma, T., Reinhard, C., Klippel, A., Tang, J., Chu, K., McGarry, T. J., Kirschner, M. W., Koths, K., Kwiatkowski, D. J. and Williams, L. T. (1997) Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278, 294-298
-
(1997)
Science
, vol.278
, pp. 294-298
-
-
Kothakota, S.1
Azuma, T.2
Reinhard, C.3
Klippel, A.4
Tang, J.5
Chu, K.6
McGarry, T.J.7
Kirschner, M.W.8
Koths, K.9
Kwiatkowski, D.J.10
Williams, L.T.11
-
16
-
-
0029959632
-
Specific cleavage of alpha-fodrin during Fas-and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1 beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease
-
16 Cryns, V. L., Bergeron, L., Zhu, H., Li, H. and Yuan, J. (1996) Specific cleavage of alpha-fodrin during Fas-and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1 beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease. J. Biol. Chem. 271, 31277-31282
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31277-31282
-
-
Cryns, V.L.1
Bergeron, L.2
Zhu, H.3
Li, H.4
Yuan, J.5
-
17
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9- dependent manner
-
17 Slee, E. A., Harte, M. T., Kluck, R. M., Wolf, B. B., Casiano, C. A., Newmeyer, D. D., Wang, H. G., Reed, J. C., Nicholson, D. W., Alnemri, E. S. et al. (1999) Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9- dependent manner. J. Cell. Biol. 144, 281-292
-
(1999)
J. Cell. Biol.
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
Newmeyer, D.D.6
Wang, H.G.7
Reed, J.C.8
Nicholson, D.W.9
Alnemri, E.S.10
-
18
-
-
15144345497
-
Pro-caspase-3 is a major physiologic target of caspase-8
-
18 Stennicke, H. R., Jurgensmeier, J. M., Shin, H., Deveraux, Q., Wolf, B. B., Yang, X., Zhou, Q., Ellerby, H. M., Ellerby, L. M., Bredesen, D. et al. (1998) Pro-caspase-3 is a major physiologic target of caspase-8. J. Biol. Chem. 273, 27084-27090
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 27084-27090
-
-
Stennicke, H.R.1
Jurgensmeier, J.M.2
Shin, H.3
Deveraux, Q.4
Wolf, B.B.5
Yang, X.6
Zhou, Q.7
Ellerby, H.M.8
Ellerby, L.M.9
Bredesen, D.10
-
19
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
19 Zou, H., Henzel, W. J., Liu, X., Lutschg, A. and Wang, X. (1997) Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
20
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
-
20 Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S. and Wang, X. (1997) Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
21
-
-
0032536771
-
Two CD95 (APO-1/Fas) signaling pathways
-
21 Scaffidi, C., Fulda, S., Srinivasan, A., Friesen, C., Li, F., Tomaselli, K. J., Debatin, K. M., Krammer, P. H. and Peter, M. E. (1998) Two CD95 (APO-1/Fas) signaling pathways. EMBO J. 17, 1675-1687
-
(1998)
EMBO J.
, vol.17
, pp. 1675-1687
-
-
Scaffidi, C.1
Fulda, S.2
Srinivasan, A.3
Friesen, C.4
Li, F.5
Tomaselli, K.J.6
Debatin, K.M.7
Krammer, P.H.8
Peter, M.E.9
-
22
-
-
0030976895
-
A sequential two-step mechanism for the production of the mature p17:P12 form of caspase-3 in vitro
-
22 Han, Z., Hendrickson, E. A., Bremner, T. A. and Wyche, J. H. (1997) A sequential two-step mechanism for the production of the mature p17:p12 form of caspase-3 in vitro. J. Biol. Chem. 272, 13432-13436
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13432-13436
-
-
Han, Z.1
Hendrickson, E.A.2
Bremner, T.A.3
Wyche, J.H.4
-
23
-
-
15844393657
-
The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis
-
23 Rotonda, J., Nicholson, D. W., Fazil, K. M., Gallant, M., Gareau, Y., Labelle, M., Peterson, E. P., Rasper, D. M., Ruel, R., Vaillancourt, J. P., Thornberry, N. A. and Becker, J. W. (1996) The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis. Nat. Struct. Biol. 3, 619-625
-
(1996)
Nat. Struct. Biol.
, vol.3
, pp. 619-625
-
-
Rotonda, J.1
Nicholson, D.W.2
Fazil, K.M.3
Gallant, M.4
Gareau, Y.5
Labelle, M.6
Peterson, E.P.7
Rasper, D.M.8
Ruel, R.9
Vaillancourt, J.P.10
Thornberry, N.A.11
Becker, J.W.12
-
24
-
-
0031668202
-
Conserved sequence elements in human main type-H1 histone gene promoters: Their role in H1 gene expression
-
24 Meergans, T., Albig, W. and Doenecke, D. (1998) Conserved sequence elements in human main type-H1 histone gene promoters: their role in H1 gene expression. Eur. J. Biochem. 256, 436-446
-
(1998)
Eur. J. Biochem.
, vol.256
, pp. 436-446
-
-
Meergans, T.1
Albig, W.2
Doenecke, D.3
-
25
-
-
0028674139
-
Interleukin-1 beta converting enzyme
-
25 Thornberry, N. A. (1994) Interleukin-1 beta converting enzyme. Methods Enzymol. 244, 615-631
-
(1994)
Methods Enzymol.
, vol.244
, pp. 615-631
-
-
Thornberry, N.A.1
-
26
-
-
0030810926
-
X-linked IAP is a direct inhibitor of cell-death proteases
-
26 Deveraux, Q. L., Takahashi, R., Salvesen, G. S. and Reed, J. C. (1997) X-linked IAP is a direct inhibitor of cell-death proteases. Nature (London) 388, 300-304
-
(1997)
Nature (London)
, vol.388
, pp. 300-304
-
-
Deveraux, Q.L.1
Takahashi, R.2
Salvesen, G.S.3
Reed, J.C.4
-
27
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
27 Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A. et al. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature (London) 376, 37-43
-
(1995)
Nature (London)
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
Gareau, Y.7
Griffin, P.R.8
Labelle, M.9
Lazebnik, Y.A.10
-
28
-
-
0032234511
-
Caspases in cell death
-
28 Dorstyn, L., Kinoshita, M. and Kumar, S. (1998) Caspases in cell death. Results Probl. Cell Differ. 24, 1-24
-
(1998)
Results Probl. Cell Differ.
, vol.24
, pp. 1-24
-
-
Dorstyn, L.1
Kinoshita, M.2
Kumar, S.3
-
29
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
29 Tewari, M., Quan, L. T., O'Rourke, K., Desnoyers, S., Zeng, Z., Beidler, D. R., Poirier, G. G., Salvesen, G. S. and Dixit, V. M. (1995) Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81, 801-809
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
30
-
-
0032522738
-
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
-
30 Deveraux, Q. L., Roy, N., Stennicke, H. R., Van Arsdale, T., Zhou, Q., Srinivasula, S. M., Alnemri, E. S., Salvesen, G. S. and Reed, J. C. (1998) IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases. EMBO J. 17, 2215-2223
-
(1998)
EMBO J.
, vol.17
, pp. 2215-2223
-
-
Deveraux, Q.L.1
Roy, N.2
Stennicke, H.R.3
Van Arsdale, T.4
Zhou, Q.5
Srinivasula, S.M.6
Alnemri, E.S.7
Salvesen, G.S.8
Reed, J.C.9
-
31
-
-
0033605722
-
Caspase-9 can be activated without proteolytic processing
-
31 Stennicke, H R., Deveraux, Q. L., Humke, E. W., Reed, J. C., Dixit, V. M and Salvesen, G. S. (1999) Caspase-9 can be activated without proteolytic processing. J. Biol. Chem. 274, 8359-8362
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 8359-8362
-
-
Stennicke, H.R.1
Deveraux, Q.L.2
Humke, E.W.3
Reed, J.C.4
Dixit, V.M.5
Salvesen, G.S.6
-
32
-
-
0030011398
-
Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death
-
32 Boldin, M. P., Goncharov, T. M., Goltsev, Y. V. and Wallach, D. (1996) Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death. Cell 85, 803-815
-
(1996)
Cell
, vol.85
, pp. 803-815
-
-
Boldin, M.P.1
Goncharov, T.M.2
Goltsev, Y.V.3
Wallach, D.4
-
33
-
-
0032549652
-
Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions
-
33 Butt, A. J., Harvey, N. L., Parasivam, G. and Kumar, S. (1998) Dimerization and autoprocessing of the Nedd2 (caspase-2) precursor requires both the prodomain and the carboxyl-terminal regions. J. Biol. Chem. 273, 6763-6768
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6763-6768
-
-
Butt, A.J.1
Harvey, N.L.2
Parasivam, G.3
Kumar, S.4
-
34
-
-
0029026548
-
Fadd, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis
-
34 Chinnaiyan, A. M., O'Rourke, K., Tewari, M and Dixit, V. M. (1995) Fadd, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis. Cell 81, 505-512
-
(1995)
Cell
, vol.81
, pp. 505-512
-
-
Chinnaiyan, A.M.1
O'Rourke, K.2
Tewari, M.3
Dixit, V.M.4
-
35
-
-
0032085941
-
Autoactivalion of procaspase-9 by Apaf-1-mediated oligomerization
-
35 Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. and Alnemri, E. S. (1998) Autoactivalion of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell. 1, 949-957
-
(1998)
Mol. Cell.
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
36
-
-
0032509354
-
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
-
36 Hu, Y., Ding, L., Spencer, D. M. and Nunez, G. (1998) WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J. Biol. Chem. 273, 33489-33494
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33489-33494
-
-
Hu, Y.1
Ding, L.2
Spencer, D.M.3
Nunez, G.4
-
37
-
-
0032562661
-
Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits
-
37 Srinivasula, S. M., Ahmad, M., MacFarlane, M., Luo, Z., Huang, Z., Fernandes-Alnemri, T and Alnemri, E. S. (1998) Generation of constitutively active recombinant caspases-3 and -6 by rearrangement of their subunits. J. Biol. Chem. 273, 10107-10111
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10107-10111
-
-
Srinivasula, S.M.1
Ahmad, M.2
MacFarlane, M.3
Luo, Z.4
Huang, Z.5
Fernandes-Alnemri, T.6
Alnemri, E.S.7
-
38
-
-
0032500552
-
Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 prodomain
-
38 Colussi, P. A., Harvey, N. L., Shearwin-Whyatt, L. M. and Kumar, S. (1998) Conversion of procaspase-3 to an autoactivating caspase by fusion to the caspase-2 prodomain. J. Biol. Chem. 273, 26566-26570
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 26566-26570
-
-
Colussi, P.A.1
Harvey, N.L.2
Shearwin-Whyatt, L.M.3
Kumar, S.4
-
39
-
-
0030698127
-
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
-
39 Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S. and Reed, J. C. (1997) The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J. 16, 6914-6925
-
(1997)
EMBO J.
, vol.16
, pp. 6914-6925
-
-
Roy, N.1
Deveraux, Q.L.2
Takahashi, R.3
Salvesen, G.S.4
Reed, J.C.5
|