XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis

Cell Death and Differentiation

Volumn 9, Issue 9, 2002, Pages 881-892

  Bratton, S B ^a   Lewis, J ^b   Butterworth, M ^a   Duckett, C S ^b   Cohen, G M ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Apaf 1 apoptosome; Bax; Caspases; CD95; Smac DIABLO; XIAP

Indexed keywords

APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CARRIER PROTEIN; CASPASE 3; CASPASE 9; FAS ANTIGEN; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN BAX; PROTEIN SUBUNIT;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME SYNTHESIS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MUTANT; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; STIMULUS RESPONSE;

ANTIGENS, CD95; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BCL-2-ASSOCIATED X PROTEIN; BINDING SITES; CAENORHABDITIS ELEGANS PROTEINS; CARRIER PROTEINS; CASPASE 3; CASPASE 9; CASPASES; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; ENZYME INHIBITORS; EUKARYOTIC CELLS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; MULTIENZYME COMPLEXES; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 0036718393     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4401069     Document Type: Article

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