X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate

Nature Structural Biology

Volumn 8, Issue 8, 2001, Pages 689-694

  Wilmouth, Rupert C ^a   Edman, Karl ^b   Neutze, Richard ^b,c   Wright, Penny A ^a   Clifton, Ian J ^a   Schneider, Thomas R ^d   Schofield, Christopher J ^a   Hajdu, Janos ^e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UPPSALA UNIVERSITY   (Sweden)

^c CHALMERS UNIVERSITY OF TECHNOLOGY   (Sweden)

^d UNIVERSITY OF GÖTTINGEN   (Germany)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; ELASTASE; GLYCINE; HEPTAPEPTIDE; HISTIDINE; SERINE; SERINE PROTEINASE;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME STRUCTURE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SECRETION; X RAY ANALYSIS;

ACYLATION; ANIMALS; BINDING SITES; CARBON; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENDORPHINS; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; MODELS, MOLECULAR; PANCREATIC ELASTASE; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; SWINE; TEMPERATURE;

EID: 0034886313     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/90401     Document Type: Article

References (31)