The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

Nature Structural Biology

Volumn 3, Issue 7, 1996, Pages 619-625

  Rotonda, Jennifer ^a   Nicholson, Donald W ^b   Fazil, Kimberly M ^b   Gallant, Michel ^b   Gareau, Yves ^b   Labelle, Marc ^b   Peterson, Erin P ^a   Rasper, Dita M ^b   Ruel, Réjean ^b   Vaillancourt, John P ^b   Thornberry, Nancy A ^a   Becker, Joseph W ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CYSTEINE PROTEINASE; INTERLEUKIN 1BETA CONVERTING ENZYME; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME SPECIFICITY; HUMAN; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; APOPTOSIS; CASPASE 3; CASPASES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE ENDOPEPTIDASES; ENZYME PRECURSORS; HUMANS; HYDROGEN BONDING; ISOENZYMES; MODELS, STRUCTURAL; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY;

CAENORHABDITIS ELEGANS; MAMMALIA;

EID: 15844393657     PISSN: 10728368     EISSN: None     Source Type: Journal    
DOI: 10.1038/nsb0796-619     Document Type: Article

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