Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Nature

Volumn 408, Issue 6815, 2000, Pages 1004-1008

  Liu, Zhihong ^a   Sun, Chaohong ^a   Olejniczak, Edward T ^a   Meadows, Robert P ^a   Betz, Stephen F ^a   Oost, Thorsten ^a   Herrmann, Julia ^b   Wu, Joe C ^b   Fesik, Stephen W ^a  

^a ABBOTT LABORATORIES   (United States)

^b PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; MEMBRANE PROTEIN; MUTANT PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTRICITY; ENZYME ACTIVATION; HUMAN; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; X RAY ANALYSIS;

AMINO ACID SEQUENCE; ANTINEOPLASTIC AGENTS; BINDING SITES; CARRIER PROTEINS; CASPASE 9; CASPASES; CLONING, MOLECULAR; CYSTEINE PROTEINASE INHIBITORS; ESCHERICHIA COLI; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAGNETIC RESONANCE SPECTROSCOPY; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STRUCTURE-ACTIVITY RELATIONSHIP; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

INTRACISTERNAL A-PARTICLES; MAMMALIA;

EID: 0034700495     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35050006     Document Type: Article

References (27)

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