-
1
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo, I., Oliver, H., Lutter, M., Luo, X. & Wang, X. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290 (1999).
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
2
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia, Z., Dickens, M., Raingeaud, J., Davis, R. J. & Greenberg, M. E. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 270, 1326-1331 (1995).
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
3
-
-
0032793067
-
B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway
-
Erhardt, P., Schremser, E. J. & Cooper, G. M. B-Raf inhibits programmed cell death downstream of cytochrome c release from mitochondria by activating the MEK/Erk pathway. Mol. Cell. Biol. 19, 5308-5315 (1999).
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5308-5315
-
-
Erhardt, P.1
Schremser, E.J.2
Cooper, G.M.3
-
4
-
-
0034103549
-
The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal
-
Le Gall, M. et al. The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal. Mol. Biol. Cell 11, 1103-1112 (2000).
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 1103-1112
-
-
Le Gall, M.1
-
5
-
-
0035102807
-
Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals
-
von Gise, A. et al. Apoptosis suppression by Raf-1 and MEK1 requires MEK- and phosphatidylinositol 3-kinase-dependent signals. Mol. Cell. Biol. 21, 2324-2336 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2324-2336
-
-
von Gise, A.1
-
6
-
-
0030947095
-
Programmed cell death in animal development
-
Jacobson, M. D., Weil, M. & Raff, M. C. Programmed cell death in animal development. Cell 88, 347-354 (1997).
-
(1997)
Cell
, vol.88
, pp. 347-354
-
-
Jacobson, M.D.1
Weil, M.2
Raff, M.C.3
-
7
-
-
0030745646
-
Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
-
Zou, H., Henzel, W. J., Liu, X., Lutschg, A. & Wang, X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90, 405-413 (1997).
-
(1997)
Cell
, vol.90
, pp. 405-413
-
-
Zou, H.1
Henzel, W.J.2
Liu, X.3
Lutschg, A.4
Wang, X.5
-
8
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
Acehan, D. et al. Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation. Mol. Cell 9, 423-432 (2002).
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
-
9
-
-
0032544449
-
Apaf 1 (CED-4 homolog) regulates programmed cell death in mammalian development
-
Cecconi, F., Alvarez-Bolado, G., Meyer, B. I., Roth, K. A. & Gruss, P. Apaf 1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 94, 727-737 (1998).
-
(1998)
Cell
, vol.94
, pp. 727-737
-
-
Cecconi, F.1
Alvarez-Bolado, G.2
Meyer, B.I.3
Roth, K.A.4
Gruss, P.5
-
10
-
-
0032544564
-
Apaf 1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida, H. et al. Apaf 1 is required for mitochondrial pathways of apoptosis and brain development. Cell 94, 739-750 (1998).
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
-
11
-
-
0032493870
-
Differential requirement for caspase 9 in apoptotic pathways in vivo
-
Hakem, R. et al. Differential requirement for caspase 9 in apoptotic pathways in vivo. Cell 94, 339-352 (1998).
-
(1998)
Cell
, vol.94
, pp. 339-352
-
-
Hakem, R.1
-
12
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida, K. et al. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 94, 325-337 (1998).
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
-
13
-
-
0033515883
-
Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition
-
Soengas, M. S. et al. Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science 284, 156-159 (1999).
-
(1999)
Science
, vol.284
, pp. 156-159
-
-
Soengas, M.S.1
-
14
-
-
0035843169
-
Inactivation of the apoptosis effector Apaf-1 in malignant melanoma
-
Soengas, M. S. et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature 409, 207-211 (2001).
-
(2001)
Nature
, vol.409
, pp. 207-211
-
-
Soengas, M.S.1
-
15
-
-
0032527705
-
The cellular response to oxidative stress: Influences of mitogen-activated protein kinase signalling pathways on cell survival
-
Wang, X., Martindale, J. L., Liu, Y. & Holbrook, N. J. The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem. J. 333, 291-300 (1998).
-
(1998)
Biochem. J.
, vol.333
, pp. 291-300
-
-
Wang, X.1
Martindale, J.L.2
Liu, Y.3
Holbrook, N.J.4
-
16
-
-
0034648698
-
Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: Inhibition by PKB/Akt but not Raf signalling
-
Rytömaa, M., Lehmann, K. & Downward, J. Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling. Oncogene 19, 4461-4468 (2000).
-
(2000)
Oncogene
, vol.19
, pp. 4461-4468
-
-
Rytömaa, M.1
Lehmann, K.2
Downward, J.3
-
17
-
-
0034671527
-
MEK inhibition enhances paclitaxel-induced tumor apoptosis
-
MacKeigan, J. P., Collins, T. S. & Ting, J. P. MEK inhibition enhances paclitaxel-induced tumor apoptosis. J. Biol. Chem. 275, 38953-38956 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38953-38956
-
-
MacKeigan, J.P.1
Collins, T.S.2
Ting, J.P.3
-
18
-
-
0036176054
-
Post-cytochrome c protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts
-
Tashker, J. S., Olson, M. & Kornbluth, S. Post-cytochrome c protection from apoptosis conferred by a MAPK pathway in Xenopus egg extracts. Mol. Biol. Cell 13, 393-401 (2002).
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 393-401
-
-
Tashker, J.S.1
Olson, M.2
Kornbluth, S.3
-
19
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1-caspase-9 complex initiates an apoptotic protease cascade
-
Li, P. et al. Cytochrome c and dATP-dependent formation of Apaf-1-caspase-9 complex initiates an apoptotic protease cascade. Cell 91, 479-489 (1997).
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
-
20
-
-
3242742565
-
-
(eds Jacobson, M. D. & McCarthy, N.) (Oxford University Press, Oxford,)
-
Clarke, P. R. in Apoptosis: The Molecular Biology of Programmed Cell Death (eds Jacobson, M. D. & McCarthy, N.) 176-199 (Oxford University Press, Oxford, 2002).
-
(2002)
Apoptosis: The Molecular Biology of Programmed Cell Death
, pp. 176-199
-
-
Clarke, P.R.1
-
21
-
-
0034306450
-
Specificity and mechanism of action of some commonly used protein kinase inhibitors
-
Davies, S. P., Reddy, H., Caivano, M. & Cohen, P. Specificity and mechanism of action of some commonly used protein kinase inhibitors. Biochem. J. 351, 95-105 (2000).
-
(2000)
Biochem. J.
, vol.351
, pp. 95-105
-
-
Davies, S.P.1
Reddy, H.2
Caivano, M.3
Cohen, P.4
-
22
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
Jiang, X. & Wang, X. Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. J. Biol. Chem. 275, 31199-31203 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31199-31203
-
-
Jiang, X.1
Wang, X.2
-
23
-
-
0032509354
-
WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation
-
Hu, Y., Ding, L., Spencer, D. M. & Nunez, G. WD-40 repeat region regulates Apaf-1 self-association and procaspase-9 activation. J. Biol. Chem. 273, 33489-33494 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33489-33494
-
-
Hu, Y.1
Ding, L.2
Spencer, D.M.3
Nunez, G.4
-
24
-
-
0032085941
-
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
-
Srinivasula, S. M., Ahmad, M., Fernandes-Alnemri, T. & Alnemri, E. S. Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization. Mol. Cell 1, 949-957 (1998).
-
(1998)
Mol. Cell
, vol.1
, pp. 949-957
-
-
Srinivasula, S.M.1
Ahmad, M.2
Fernandes-Alnemri, T.3
Alnemri, E.S.4
-
25
-
-
0032515027
-
Regulation of cell death protease caspase-9 by phosphorylation
-
Cardone, M. H. et al. Regulation of cell death protease caspase-9 by phosphorylation. Science 282, 1318-1321 (1998).
-
(1998)
Science
, vol.282
, pp. 1318-1321
-
-
Cardone, M.H.1
-
26
-
-
0035958732
-
Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway
-
Mody, N., Leitch, J., Armstrong, C., Dixon, J. & Cohen, P. Effects of MAP kinase cascade inhibitors on the MKK5/ERK5 pathway. FEBS Lett. 502, 21-24 (2001).
-
(2001)
FEBS Lett.
, vol.502
, pp. 21-24
-
-
Mody, N.1
Leitch, J.2
Armstrong, C.3
Dixon, J.4
Cohen, P.5
-
27
-
-
0036479531
-
Regulation of cell number by MAPK-dependent control of apoptosis: A mechanism for trophic survival signaling
-
Bergmann, A., Tugentman, M., Shilo, B. Z. & Steller, H. Regulation of cell number by MAPK-dependent control of apoptosis: a mechanism for trophic survival signaling. Dev. Cell 2, 159-170 (2002).
-
(2002)
Dev. Cell
, vol.2
, pp. 159-170
-
-
Bergmann, A.1
Tugentman, M.2
Shilo, B.Z.3
Steller, H.4
-
28
-
-
0032582662
-
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
-
Bergmann, A., Agapite, J., McCall, K. & Steller, H. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Cell 95, 331-341 (1998).
-
(1998)
Cell
, vol.95
, pp. 331-341
-
-
Bergmann, A.1
Agapite, J.2
McCall, K.3
Steller, H.4
-
29
-
-
0032582793
-
Ras promotes cell survival in Drosophila by downregulating hid expression
-
Kurada, P. & White, K. Ras promotes cell survival in Drosophila by downregulating hid expression. Cell 95, 319-329 (1998).
-
(1998)
Cell
, vol.95
, pp. 319-329
-
-
Kurada, P.1
White, K.2
-
30
-
-
0035375261
-
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth
-
Sapkota, G. P. et al. Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell growth. J. Biol. Chem. 276, 19469-19482 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 19469-19482
-
-
Sapkota, G.P.1
|