Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway

Journal of Biological Chemistry

Volumn 279, Issue 33, 2004, Pages 35047-35052

  Wagner, Klaus W ^a,b   Engels, Ingo H ^a   Deveraux, Quinn L ^a,c  

^a GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^b GENENTECH INC   (United States)

^c GNF   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; CHEMICAL ACTIVATION; PHYSIOLOGY;

APOPTOSIS; CASPASE; CLEAVAGE; ORGANELLE;

ENZYMES;

CASPASE 2; CASPASE 8; DEATH RECEPTOR 5; ETOPOSIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; STAUROSPORINE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; APOPTOSIS REGULATORY PROTEIN; BAX PROTEIN, HUMAN; BID PROTEIN, HUMAN; CARRIER PROTEIN; CASP3 PROTEIN, HUMAN; CASP7 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CASPASE; CASPASE 3; CASPASE 7; MEMBRANE PROTEIN; ONCOPROTEIN; SMALL INTERFERING RNA; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TNFSF10 PROTEIN, HUMAN; TUMOR NECROSIS FACTOR ALPHA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DOWNSTREAM PROCESSING; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROCESSING; RNA INTERFERENCE; ANIMAL; BIOLOGICAL MODEL; CELL DEATH; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DOWN REGULATION; GENETIC TRANSFECTION; METABOLISM; MITOCHONDRION; PHYSIOLOGY; TIME; WESTERN BLOTTING;

MAMMALIA;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; BLOTTING, WESTERN; CARRIER PROTEINS; CASPASE 2; CASPASE 3; CASPASE 7; CASPASE 8; CASPASES; CELL DEATH; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ETOPOSIDE; GENE SILENCING; HUMANS; MEMBRANE GLYCOPROTEINS; MITOCHONDRIA; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RNA INTERFERENCE; RNA, SMALL INTERFERING; STAUROSPORINE; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 4544274785     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M400708200     Document Type: Article

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