-
1
-
-
0036300214
-
The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis
-
Wilson, R. et al. The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis. Nature Cell Biol. 4, 445-450 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 445-450
-
-
Wilson, R.1
-
2
-
-
0036566395
-
Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark
-
Rodriguez, A., Chen, P., Oliver, H. & Abrams, J. M. Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark. EMBO J. 21, 2189-2197 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2189-2197
-
-
Rodriguez, A.1
Chen, P.2
Oliver, H.3
Abrams, J.M.4
-
3
-
-
0033980888
-
Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila
-
Lisi, S., Mazzon, I. & White, K. Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila. Genetics 154, 669-678 (2000).
-
(2000)
Genetics
, vol.154
, pp. 669-678
-
-
Lisi, S.1
Mazzon, I.2
White, K.3
-
4
-
-
0033588273
-
The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
-
Wang, S. L., Hawkins, C. J., Yoo, S. J., Muller, H. A. & Hay, B. A. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID. Cell 98, 453-463 (1999).
-
(1999)
Cell
, vol.98
, pp. 453-463
-
-
Wang, S.L.1
Hawkins, C.J.2
Yoo, S.J.3
Muller, H.A.4
Hay, B.A.5
-
5
-
-
0034651791
-
Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function
-
Goyal, L., McCall, K., Agapite, J., Hartwieg, E. & Steller, H. Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function. EMBO J. 19, 589-597 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 589-597
-
-
Goyal, L.1
McCall, K.2
Agapite, J.3
Hartwieg, E.4
Steller, H.5
-
6
-
-
0036300082
-
Apoptosis inducers Hid, Rpr and Grim negatively regulate levels of the caspase inhibitor DIAP1 by distinct mechanisms
-
Yoo, S. J. et al. Apoptosis inducers Hid, Rpr and Grim negatively regulate levels of the caspase inhibitor DIAP1 by distinct mechanisms. Nature Cell Biol. 4, 416-424 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 416-424
-
-
Yoo, S.J.1
-
7
-
-
0037189566
-
Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC
-
Igaki, T., Yamamoto-Goto, Y., Tokushige, N., Kanda, H. & Miura, M. Down-regulation of DIAP1 triggers a novel Drosophila cell death pathway mediated by Dark and DRONC. J. Biol. Chem. 277, 23103-23106 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 23103-23106
-
-
Igaki, T.1
Yamamoto-Goto, Y.2
Tokushige, N.3
Kanda, H.4
Miura, M.5
-
8
-
-
0032828715
-
A generic protein purification method for protein complex characterization and proteome exploration
-
Rigaut, G. et al. A generic protein purification method for protein complex characterization and proteome exploration. Nature Biotechnol. 17, 1030-1032 (1999).
-
(1999)
Nature Biotechnol.
, vol.17
, pp. 1030-1032
-
-
Rigaut, G.1
-
9
-
-
0029955228
-
Using ubiquitin to follow the metabolic fate of a protein
-
Levy, F., Johnsson, N., Rumenapf, T. & Varshavsky, A. Using ubiquitin to follow the metabolic fate of a protein. Proc. Natl Acad. Sci. USA 93, 4907-4912 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4907-4912
-
-
Levy, F.1
Johnsson, N.2
Rumenapf, T.3
Varshavsky, A.4
-
10
-
-
0034581529
-
Ubiquitin fusion technique and its descendants
-
Varshavsky, A. Ubiquitin fusion technique and its descendants. Methods Enzymol. 327, 578-593 (2000).
-
(2000)
Methods Enzymol.
, vol.327
, pp. 578-593
-
-
Varshavsky, A.1
-
11
-
-
0023003380
-
In vivo half-life of a protein is a function of its amino-terminal residue
-
Bachmair, A., Finley, D. & Varshavsky, A. In vivo half-life of a protein is a function of its amino-terminal residue. Science 234, 179-186 (1986).
-
(1986)
Science
, vol.234
, pp. 179-186
-
-
Bachmair, A.1
Finley, D.2
Varshavsky, A.3
-
12
-
-
0034704098
-
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila
-
Quinn, L. M. et al. An essential role for the caspase dronc in developmentally programmed cell death in Drosophila. J. Biol. Chem. 275, 40416-40424 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40416-40424
-
-
Quinn, L.M.1
-
13
-
-
0034651987
-
The Drosophila caspase DRONC is regulated by DIAP1
-
Meier, P., Silke, J., Leevers, S. J. & Evan, G. I. The Drosophila caspase DRONC is regulated by DIAP1. EMBO J. 19, 598-611 (2000).
-
(2000)
EMBO J.
, vol.19
, pp. 598-611
-
-
Meier, P.1
Silke, J.2
Leevers, S.J.3
Evan, G.I.4
-
14
-
-
0034282666
-
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM
-
Hawkins, C. J. et al. The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM. J. Biol. Chem. 275, 27084-27093 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 27084-27093
-
-
Hawkins, C.J.1
-
15
-
-
0033057366
-
A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1
-
Hawkins, C. J., Wang, S. L. & Hay, B. A. A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1. Proc. Natl Acad. Sci. USA 96, 2885-2890 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2885-2890
-
-
Hawkins, C.J.1
Wang, S.L.2
Hay, B.A.3
-
16
-
-
0032573595
-
The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE
-
Kaiser, W. J., Vucic, D. & Miller, L. K. The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE. FEBS Lett. 440, 243-248 (1998).
-
(1998)
FEBS Lett.
, vol.440
, pp. 243-248
-
-
Kaiser, W.J.1
Vucic, D.2
Miller, L.K.3
-
17
-
-
0034296394
-
The ubiquitin system
-
Hershko, A., Ciechanover, A. & Varshavsky, A. The ubiquitin system. Nature Med. 6, 1073-1081 (2000).
-
(2000)
Nature Med.
, vol.6
, pp. 1073-1081
-
-
Hershko, A.1
Ciechanover, A.2
Varshavsky, A.3
-
18
-
-
0029861143
-
The N-end rule: Functions, mysteries, uses
-
Varshavsky, A. The N-end rule: functions, mysteries, uses. Proc. Natl Acad. Sci. USA 93, 12142-12149 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12142-12149
-
-
Varshavsky, A.1
-
19
-
-
0032502719
-
Lactacystin, proteasome function, and cell fate
-
Fenteany, G. & Schreiber, S. L. Lactacystin, proteasome function, and cell fate. J. Biol. Chem. 273, 8545-8548 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 8545-8548
-
-
Fenteany, G.1
Schreiber, S.L.2
-
20
-
-
0037112776
-
Dissection of c-MOS degron
-
Sheng, J., Kumagai, A., Dunphy, W. G. & Varshavsky, A. Dissection of c-MOS degron. EMBO J. 21, 6061-6071 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 6061-6071
-
-
Sheng, J.1
Kumagai, A.2
Dunphy, W.G.3
Varshavsky, A.4
-
21
-
-
0036300083
-
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
-
Ryoo, H. D., Bergmann, A., Gonen, H., Ciechanover, A. & Steller, H. Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1. Nature Cell Biol, 4, 432-438 (2002).
-
(2002)
Nature Cell Biol.
, vol.4
, pp. 432-438
-
-
Ryoo, H.D.1
Bergmann, A.2
Gonen, H.3
Ciechanover, A.4
Steller, H.5
-
22
-
-
0001687306
-
Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway
-
Kwon, Y. T. et al. Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway. Mol. Cell. Biol. 20, 4135-4148 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 4135-4148
-
-
Kwon, Y.T.1
-
23
-
-
0029161958
-
The head involution defective gene of Drosophila melanogaster functions in programmed cell death
-
Grether, M. E., Abrams, J. M., Agapite, J., White, K. & Steller, H. The head involution defective gene of Drosophila melanogaster functions in programmed cell death. Genes Dev. 9, 1694-1708 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 1694-1708
-
-
Grether, M.E.1
Abrams, J.M.2
Agapite, J.3
White, K.4
Steller, H.5
-
24
-
-
0029583176
-
Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
-
Hay, B. A., Wassarman, D. A. & Rubin, G. M. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death. Cell 83, 1253-1262 (1995).
-
(1995)
Cell
, vol.83
, pp. 1253-1262
-
-
Hay, B.A.1
Wassarman, D.A.2
Rubin, G.M.3
-
25
-
-
0030021282
-
Cell killing by the Drosophila gene reaper
-
White, K., Tahaoglu, E. & Steller, H. Cell killing by the Drosophila gene reaper. Science 271, 805-807 (1996).
-
(1996)
Science
, vol.271
, pp. 805-807
-
-
White, K.1
Tahaoglu, E.2
Steller, H.3
-
26
-
-
0035166684
-
Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3α) of the N-end rule pathway
-
Kwon, Y. T., Xia, Z., Davydov, I. V., Lecker, S. H. & Varshavsky, A. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3α) of the N-end rule pathway. Mol. Cell. Biol. 21, 8007-8021 (2001).
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 8007-8021
-
-
Kwon, Y.T.1
Xia, Z.2
Davydov, I.V.3
Lecker, S.H.4
Varshavsky, A.5
-
27
-
-
0033485869
-
The E2-E3 interaction in the N-end rule pathway: The RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain
-
Xie, Y. & Varshavsky A. The E2-E3 interaction in the N-end rule pathway: the RING-H2 finger of E3 is required for the synthesis of multiubiquitin chain. EMBO J. 18, 6832-6844 (1999).
-
(1999)
EMBO J.
, vol.18
, pp. 6832-6844
-
-
Xie, Y.1
Varshavsky, A.2
-
28
-
-
0035912183
-
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
-
Rao, H., Uhlmann, F., Nasmyth, K. & Varshavsky, A. Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410, 955-959 (2001).
-
(2001)
Nature
, vol.410
, pp. 955-959
-
-
Rao, H.1
Uhlmann, F.2
Nasmyth, K.3
Varshavsky, A.4
-
29
-
-
0030805140
-
The Listeria monocytogenes-secreted p60 protein is an N-end rule substrate in the cytosol of infected cells, Implications for major histocompatibility complex class 1 antigen processing of bacterial proteins
-
Sijts, A. J., Pilip, I. & Pamer, E. G. The Listeria monocytogenes-secreted p60 protein is an N-end rule substrate in the cytosol of infected cells, Implications for major histocompatibility complex class 1 antigen processing of bacterial proteins. J. Biol. Chem. 272, 19261-19268 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 19261-19268
-
-
Sijts, A.J.1
Pilip, I.2
Pamer, E.G.3
-
30
-
-
0034703066
-
Degradation of HIV-1 integrase by the N-end rule pathway
-
Mulder, L. C. & Muesing, M. A. Degradation of HIV-1 integrase by the N-end rule pathway. J. Biol. Chem. 275, 29749-29753 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 29749-29753
-
-
Mulder, L.C.1
Muesing, M.A.2
-
31
-
-
0035902601
-
Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death
-
Suzuki, Y., Nakabayashi, Y. & Takahashi, R. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc. Natl Acad. Sci. USA 98, 8662-8667 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 8662-8667
-
-
Suzuki, Y.1
Nakabayashi, Y.2
Takahashi, R.3
-
32
-
-
0034607655
-
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
-
Yang, Y., Fang, S., Jensen, J. P., Weissman, A. M. & Ashwell, J. D. Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli. Science 288, 874-877 (2000).
-
(2000)
Science
, vol.288
, pp. 874-877
-
-
Yang, Y.1
Fang, S.2
Jensen, J.P.3
Weissman, A.M.4
Ashwell, J.D.5
-
33
-
-
0034282432
-
The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
-
Huang, H. et al. The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7. J. Biol. Chem, 275, 26661-26664 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26661-26664
-
-
Huang, H.1
-
34
-
-
0037184113
-
Proteasome-mediated degradation of Smac during apoptoxis: XIAP promotes Smac ubiquitination in vitro
-
MacFarlane, M., Merrison, W, Bratton, S. B. & Cohen, G. M. Proteasome-mediated degradation of Smac during apoptoxis: XIAP promotes Smac ubiquitination in vitro, J. Biol. Chem. 277, 36611-36616 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36611-36616
-
-
MacFarlane, M.1
Merrison, W.2
Bratton, S.B.3
Cohen, G.M.4
-
35
-
-
0037423358
-
Reaper is regulated by IAP-mediated ubiquitination
-
Olson, M. R. et al. Reaper is regulated by IAP-mediated ubiquitination. J. Biol. Chem. 278, 4028-4034 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 4028-4034
-
-
Olson, M.R.1
-
36
-
-
0037855783
-
cIAP1 and cIAP2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO
-
Hu, S. & Yang, X. cIAP1 and cIAP2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. J. Biol. Chem. 278, 10055-10060 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10055-10060
-
-
Hu, S.1
Yang, X.2
-
37
-
-
0343729328
-
Perinuclear localization of the protein-tyrosine phosphatase SHP-1 and inhibition of epidermal growth factor-stimulated STAT1/3 activation in A431 cells
-
Tenev, T. et al. Perinuclear localization of the protein-tyrosine phosphatase SHP-1 and inhibition of epidermal growth factor-stimulated STAT1/3 activation in A431 cells. Eur. J. Cell Biol. 79, 261-271 (2000).
-
(2000)
Eur. J. Cell Biol.
, vol.79
, pp. 261-271
-
-
Tenev, T.1
-
38
-
-
0036791634
-
Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1
-
Tenev, T., Zachariou, A., Wilson, R., Paul, A. & Meier, P. Jafrac2 is an IAP antagonist that promotes cell death by liberating Dronc from DIAP1. EMBO J. 21, 5118-5129 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 5118-5129
-
-
Tenev, T.1
Zachariou, A.2
Wilson, R.3
Paul, A.4
Meier, P.5
-
39
-
-
0032582662
-
The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling
-
Bergmann, A., Agapite, J., McCall, K. & Steller, H. The Drosophila gene hid is a direct molecular target of Ras-dependent survival signaling. Cell 95, 331-341 (1998).
-
(1998)
Cell
, vol.95
, pp. 331-341
-
-
Bergmann, A.1
Agapite, J.2
McCall, K.3
Steller, H.4
|