Granzyme B mimics apical caspases: Description of a unified pathway for trans-activation of executioner caspase-3 and -7

Journal of Biological Chemistry

Volumn 273, Issue 51, 1998, Pages 34278-34283

  Yang, Xiaohe ^a   Stennicke, Henning R ^b   Wang, Baikun ^a   Green, Doug R ^e   Jänicke, Reiner U ^c   Srinivasan, Anu ^d   Seth, Prem ^f   Salvesen, Guy S ^b   Froelich, Christopher J ^a,g  

^a EVANSTON NORTHWESTERN HEALTHCARE   (United States)

^b BURNHAM INSTITUTE   (United States)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d PFIZER INC   (United States)

^e LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^f NATIONAL CANCER INSTITUTE   (United States)

^g Evanston North western Healthcare Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYSTEINE PROTEINASE; GRANZYME B; RECOMBINANT ENZYME;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN MCF 7; CYTOTOXICITY; ENZYME ACTIVATION; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; TRANSACTIVATION;

APOPTOSIS; BREAST NEOPLASMS; CASPASE 10; CASPASE 3; CASPASE 7; CASPASES; ENZYME PRECURSORS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GRANZYMES; HUMANS; KINETICS; MACROMOLECULAR SUBSTANCES; MODELS, BIOLOGICAL; PROTEIN PROCESSING, POST-TRANSLATIONAL; SERINE ENDOPEPTIDASES; TRANS-ACTIVATION (GENETICS); TUMOR CELLS, CULTURED;

ESCHERICHIA COLI; MINK CELL FOCUS-FORMING VIRUS;

EID: 0032545286     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.51.34278     Document Type: Article

References (34)

1. Salvesen, G. S., and Dixit, V. M. (1997) Cell 91, 443-446
2. Froelich, C. J., Dixit, V. M., and Yang, X. (1998) Immunol. Today 19, 30-36
3. Muzio, M., Stockwell, B. R., Stennicke, H. R., Salvesen, G. S., and Dixit, V. M. (1998) J. Biol. Chem. 273, 2926-2930
4. Susin, S. A., Zamzami, N., Castedo, M., Daugas, E., Wang, H. G., Geley, S., Fassy, F., Reed, J. C., and Kroemer, G. (1997) J. Exp. Med. 186, 25-37
5. Li, P., Nijhawan, D., Budihardjo, I., Srinivasula, S. M., Ahmad, M., Alnemri, E. S., and Wang, X. D. (1997) Cell 91, 479-489
6. Froelich, C. J., Orth, K., Turbov, J., Seth, P., Babior, B. M., Gottlieb, R. A., Shah, G. M., Bleackley, R. C., Dixit, V. M., and Hanna, W. L. (1996) J. Biol. Chem. 271, 29073-29081
7. Stoorvogel, W., Strous, G. J., Geuze, H. J., Oorschot, V., and Schwartz, A. L. (1991) Cell 65, 417-427
8. Darmon, A. J., Nicholson, D. W., and Bleackley, R. C. (1995) Nature 377, 446-448
9. Quan, L. T., Tewari, M., O'Rourke, K., Dixit, V. M., Snipas, S. J., Poirier, G. G., Ray, C., Pickup, D. J., and Salvesen, G. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 1972-1976
10. Martin, S. J., Amarante-Mendes, G. P., Shi, L. F., Chuang, T. H., Casiano, C. A., O'Brien, G. A., Fitzgerald, P., Tan, E. M., Bokoch, G. M., Greenberg, A. H., and Green, D. R. (1996) EMBO J. 15, 2407-2416
11. Chinnaiyan, A. M., Orth, K., Hanna, W. L., Duan, H. J., Poirier, G. G., Froelich, C. J., and Dixit, V. M. (1996) Curr. Biol. 6, 897-899
12. Gu, Y., Sarnecki, C., Fleming, M. A., Lippke, J. A., Bleackley, R. C., and Su, M. S. S. (1996) J. Biol. Chem. 271, 10816-10820
13. Fernandes-Alnemri, T., Takahashi, A., Armstrong, R., Krebs, J., Fritz, L., Tomaselli, K. J., Wang, L., Yu, Z., Croce, C. M., Salvesen, G. S., Earnshaw, W. C., Litwack, G., and Alnemri, E. S. (1995) Cancer Res. 55, 6045-6052
14. Orth, K., Chinnaiyan, A. M., Garg, M., Froelich, C. J., and Dixit, V. M. (1996) J. Biol. Chem. 271, 16443-16446
15. Fernandes-Alnemri, T., Litwack, G., and Alnemri, E. S. (1995) Cancer Res. 55, 2737-2742
16. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Scaffidi, C., Bretz, J. D., Zhang, M., Ni, J., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 86, 817-821
17. Duan, H. J., Orth, K., Chinnaiyan, A. M., Poirier, G. G., Froelich, C. J., He, W.-W., and Dixit, V. M. (1996) J. Biol. Chem. 271, 16720-16724
18. Fernandes-Alnemri, T., Armstrong, R. C., Krebs, J., Srinivasula, S. M., Wang, L., Bullrich, F., Fritz, L. C., Trapani, J. A., Tomaselli, K. J., Litwack, G., and Alnemri, E. S. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 7464-7469
19. Vincenz, C., and Dixit, V. M. (1997) J. Biol. Chem. 272, 6578-6583
20. Shi, L. F., Chen, G., MacDonald, G., Bergeron, L., Li, H. L., Miura, M., Rotello, R. J., Miller, D. K., Li, P., Seshadri, T., Yuan, J. Y., and Greenberg, A. H. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 11002-11007
21. Talanian, R. V., Yang, X., Turbov, J., Seth, P., Ghayur, T., Casiano, C. A., and Froelich, C. J. (1997) J. Exp. Med. 186, 1323-1331
22. Zhou, Q., and Salvesen, G. S. (1997) Biochem. J. 324, 361-364
23. Jänicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) J. Biol. Chem. 273, 9357-9360
24. Scaffidi, C., Fulda, S., Srinivasan, A., Friesen, C., Li, F., Tomaselli, K. J., Debatin, K. M., Krammer, P. H., and Peter, M. E. (1998) EMBO J. 17, 1675-1687
25. Hanna, W. L., Zhang, X., Turbov, J., Winkler, U., Hudig, D., and Froelich, C. J. (1993) Protein Purif. Exp. 4, 398-402
26. Seth, P. (1994) Biochem. Biophys. Res. Commun. 203, 582-587
27. Roy, N., Deveraux, Q. L., Takahashi, R., Salvesen, G. S., and Reed, J. C. (1997) EMBO J. 16, 6914-6925
28. Orth, K., O'Rourke, K., Salvesen, G. S., and Dixit, V. M. (1996) J. Biol. Chem. 271, 20977-20980
29. Thornberry, N. A., Rano, T. A., Peterson, E. P., Rasper, D. M., Timkey, T., Garcia-Calvo, M., Houtzager, V. M., Nordstrom, P. A., Roy, S., Vaillancourt, J. P., Chapman, K. T., and Nicholson, D. W. (1997) J. Biol. Chem. 272, 17907-17911
30. Medema, J. P., Toes, R. E. M., Scaffidi, C., Zheng, T. S., Flavell, R. A., Melief, C. J. M., Peter, M. E., Offringa, R., and Krammer, P. H. (1997) Eur. J. Immunol. 27, 3492-3498
31. Reed, J. C. (1997) Cell 91, 559-562
32. Srinivasula, S. M., Fernandes-Alnemri, T., Zangrillia, J., Robertson, N., Armstrong, R. C., Wang, L., Trapani, J. A., Tomaselli, K. J., Litwack, G., and Alnemri, E. S. (1996) J. Biol. Chem. 271, 27099-27106
33. Chandler, J. M., Cohen, G. M., and MacFarlane, M. (1998) J. Biol. Chem. 273, 10815-10818
34. Stennicke, H. R., Jurngensmeier, J. M., Shin, H., Wolf, B., Yang, X., Zhou, Q., Ellerby, H. M., Ellerby, L. M., Bredesen, D. E., Green, D. R., Reed, J. C., Froelich, C. J., and Salvesen, G. S. (1998) J. Biol. Chem. 273, 27084-27090