Regulation of cell death protease caspase-9 by phosphorylation

Science

Volumn 282, Issue 5392, 1998, Pages 1318-1321

  Cardone, Michael H ^a,b   Roy, Natalie ^c   Stennicke, Henning R ^c   Salvesen, Guy S ^c   Franke, Thomas F ^a   Stanbridge, Eric ^d   Frisch, Steven ^c   Reed, John C ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE;

APOPTOSIS; ARTICLE; CELL DEATH; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM;

EID: 0032515027     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.282.5392.1318     Document Type: Article

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44. We thank J. Rhim for 267 Ki-Ras cells; T. G. Sambandan for mass spectroscopy advice; I. Tamm for IAP measurements; S. Kitada for help with cell lines; T. Bobo, A. Sinskey, and P. Sorger for support and the members of the Reed lab for helpful discussions. This work was partially supported by a Biomeasure grant to M.C., a Department of Defense Breast Cancer grant to N.R., a Danish Natural Science Foundation grant (9600412) to H.R.S., and grants CA-69381 and CA-69515 from NIH and the National Cancer Institute.