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Volumn 27, Issue 2, 2002, Pages 94-101

Reprieval from execution: The molecular basis of caspase inhibition

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE INHIBITOR; CYTOKINE RESPONSE MODIFIER A; INHIBITOR OF APOPTOSIS PROTEIN; PROTEIN P35; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 0036470319     PISSN: 09680004     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0004(01)02045-X     Document Type: Review
Times cited : (156)

References (59)
  • 1
    • 0026517239 scopus 로고
    • Molecular cloning of the interleukin-1β converting enzyme
    • (1992) Science , vol.256 , pp. 97-100
    • Cerretti, D.P.1
  • 2
    • 0026507126 scopus 로고
    • A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes
    • (1992) Nature , vol.356 , pp. 768-774
    • Thornberry, N.A.1
  • 3
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1
  • 4
    • 0009530192 scopus 로고    scopus 로고
    • Human ICE/CED-3 protease nomenclature
    • (1996) Cell , vol.87 , pp. 171
    • Alnemri, E.S.1
  • 13
    • 0034687422 scopus 로고    scopus 로고
    • Structure of a serpin-protease complex shows inhibition by deformation
    • (2000) Nature , vol.407 , pp. 923-926
    • Huntington, J.A.1
  • 14
    • 0034921727 scopus 로고    scopus 로고
    • Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs
    • (2001) Genome Biol. , vol.2 , pp. 3009
    • Verhagen, A.M.1
  • 15
    • 0034967005 scopus 로고    scopus 로고
    • Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4292-4301
    • Richter, B.W.1
  • 16
    • 0032078249 scopus 로고    scopus 로고
    • Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts
    • (1998) Trends Biochem. Sci. , vol.23 , pp. 159-162
    • Uren, A.G.1
  • 18
    • 0035831021 scopus 로고    scopus 로고
    • Structural basis of caspase-7 inhibition by XIAP
    • (2001) Cell , vol.104 , pp. 769-780
    • Chai, J.1
  • 19
    • 0035831022 scopus 로고    scopus 로고
    • Structural basis of caspase inhibition by XIAP: Differential roles of the linker versus the BIR domain
    • (2001) Cell , vol.104 , pp. 781-790
    • Huang, Y.1
  • 20
    • 0035831019 scopus 로고    scopus 로고
    • Structural basis for the inhibition of caspase-3 by XIAP
    • (2001) Cell , vol.104 , pp. 791-800
    • Riedl, S.J.1
  • 21
    • 0033592470 scopus 로고    scopus 로고
    • NMR structure and mutagenesis of the inhibitor-of-apoptosis protein XIAP
    • (1999) Nature , vol.401 , pp. 818-822
    • Sun, C.1
  • 22
    • 0034785591 scopus 로고    scopus 로고
    • A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
    • (2001) Mol. Cell , vol.8 , pp. 613-621
    • Suzuki, Y.1
  • 23
    • 0025301658 scopus 로고
    • The refined 2.4 Å X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: A novel type of proteinase inhibitor interaction
    • (1990) EMBO J. , vol.9 , pp. 1939-1947
    • Stubbs, M.T.1
  • 24
    • 0025329390 scopus 로고
    • The structure of a complex of recombinant hirudin and human α-thrombin
    • (1990) Science , vol.249 , pp. 277-280
    • Rydel, T.J.1
  • 26
    • 0034721940 scopus 로고    scopus 로고
    • NMR structure and mutagenesis of the third BIR domain of the inhibitor of apoptosis protein XIAP
    • (2000) J. Biol. Chem. , vol.275 , pp. 33777-33781
    • Sun, C.1
  • 28
    • 0035282570 scopus 로고    scopus 로고
    • A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
    • (2001) Nature , vol.410 , pp. 112-116
    • Srinivasula, S.M.1
  • 30
    • 0035879051 scopus 로고    scopus 로고
    • Inhibition of distant caspase homologs by natural caspase inhibitors
    • (2001) Biochem. J. , vol.357 , pp. 575-580
    • Snipas, S.J.1
  • 31
    • 0032575309 scopus 로고    scopus 로고
    • Interaction of the baculovirus anti-apoptotic protein p35 with caspases: Specificity, kinetics, and characterization of the caspase/p35 complex
    • (1998) Biochemistry , vol.37 , pp. 10757-10765
    • Zhou, Q.1
  • 32
    • 0030849093 scopus 로고    scopus 로고
    • A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    • (1997) J. Biol. Chem. , vol.272 , pp. 17907-17911
    • Thornberry, N.A.1
  • 33
    • 0035932465 scopus 로고    scopus 로고
    • Covalent inhibition revealed by the crystal structure of the caspase-8/p35 complex
    • (2001) Nature , vol.410 , pp. 494-497
    • Xu, G.1
  • 34
    • 0035818438 scopus 로고    scopus 로고
    • Mechanism based inactivation of caspases by the apoptotic suppressor p35
    • (2001) Biochemistry , vol.40 , pp. 13274-13280
    • Riedl, S.J.1
  • 35
    • 0345654358 scopus 로고    scopus 로고
    • Crystal structure of baculovirus P35: Role of a novel reactive site loop in apoptotic caspase inhibition
    • (1999) EMBO J. , vol.18 , pp. 2031-2039
    • Fisher, A.J.1
  • 37
    • 0028170376 scopus 로고
    • Structure and mechanism of interleukin-1 β converting enzyme
    • (1994) Nature , vol.370 , pp. 270-275
    • Wilson, K.P.1
  • 39
    • 0035823595 scopus 로고    scopus 로고
    • The serpins are an expanding superfamily of structurally similar but funtionally diverse proteins: Evolution, mechanism of inhibition, novel functions, and a revised nomenclature
    • (2001) J. Biol. Chem. , vol.276 , pp. 33293-33296
    • Silverman, G.A.1
  • 41
    • 0030977847 scopus 로고    scopus 로고
    • Target protease specificity of the viral serpin CrmA: Analysis of five caspases
    • (1997) J. Biol. Chem. , vol.273 , pp. 7797-7800
    • Zhou, Q.1
  • 42
    • 0033568456 scopus 로고    scopus 로고
    • Caspase-1 (interleukin-1β-converting enzyme) is inhibited by the human serpin analogue proteinase inhibitor 9
    • (1999) Biochem. J. , vol.342 , pp. 655-665
    • Annand, R.R.1
  • 43
    • 0031792776 scopus 로고    scopus 로고
    • Selective regulation of apoptosis: The cytotoxic lymphocyte serpin proteinase inhibitor 9 protects against granzyme B-mediated apoptosis without perturbing the Fas cell death pathway
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6387-6398
    • Bird, C.H.1
  • 44
    • 0034283578 scopus 로고    scopus 로고
    • Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
    • (2000) Biochem. J. , vol.350 , pp. 563-568
    • Stennicke, H.R.1
  • 46
  • 47
    • 0031027297 scopus 로고    scopus 로고
    • Activation of a CrmA-insensitive, p35-sensitive pathway in ionizing radiation-induced apoptosis
    • (1997) J. Biol. Chem. , vol.272 , pp. 1965-1969
    • Datta, R.1
  • 48
    • 0033841662 scopus 로고    scopus 로고
    • Crystal structure of viral serpin crmA provides insights into its mechanism of cysteine proteinase inhibition
    • (2000) Protein Sci. , vol.9 , pp. 1423-1427
    • Simonovic, M.1
  • 49
    • 0028168514 scopus 로고
    • Inhibition of interleukin-1β converting enzyme by the cowpox virus serpin CrmA. An example of cross-class inhibition
    • (1994) J. Biol. Chem. , vol.269 , pp. 19331-19337
    • Komiyama, T.1
  • 52
    • 0025788321 scopus 로고
    • Mechanism of serpin action: Evidence that C1 inhibitor functions as a suicide substrate
    • (1991) Biochemistry , vol.30 , pp. 8876-8882
    • Patston, P.A.1
  • 53
    • 0028773279 scopus 로고
    • Biological implications of 3Å structure of dimeric antithrombin
    • (1994) Structure , vol.2 , pp. 257-270
    • Carrell, R.W.1
  • 54
    • 0021677986 scopus 로고
    • In vivo significance of kinetic constants of protein proteinase inhibitors
    • (1984) Biochem. Med. , vol.32 , pp. 387-397
    • Bieth, J.G.1
  • 55
    • 0028955325 scopus 로고
    • Granzyme B is inhibited by the cowpox virus serpin CrmA
    • (1995) J. Biol. Chem. , vol.270 , pp. 10377-10379
    • Quan, L.T.1
  • 56
    • 0029914132 scopus 로고    scopus 로고
    • A cytosolic granzyme B inhibitor related to the viral apoptotic regulator cytokine response modifier A is present in cytotoxic lymphocytes
    • (1996) J. Biol. Chem. , vol.271 , pp. 27802-27809
    • Sun, J.1
  • 57
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 59


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.