Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

Cell

Volumn 102, Issue 1, 2000, Pages 43-53

  Verhagen, Anne M ^a   Ekert, Paul G ^a,b   Pakusch, Miha ^a   Silke, John ^a   Connolly, Lisa M ^a   Reid, Gavin E ^a   Moritz, Robert L ^a   Simpson, Richard J ^a   Vaux, David L ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MASS SPECTROMETRY; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION;

INTRACISTERNAL A-PARTICLES; MAMMALIA;

EID: 0034616942     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)00009-X     Document Type: Article

References (34)

1. Human ICE/CED-3 protease nomenclature
2. Involvement of mach, a novel mort1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death
3. A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo - Polyethylenimine
4. Grim, a novel cell death gene in drosophila
5. An apoptosis inhibiting baculovirus gene with a zinc finger like motif
6. X-linked IAP is a direct inhibitor of cell-death proteases
7. IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
8. DRONC, an ecdysone-inducible Drosophila caspase
9. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating lAP inhibition
10. A conserved family of cellular genes related to the baculovirus IAP gene and encoding apoptosis inhibitors
11. Inhibition of apoptosis and clonogenic survival of cells expressing crmA variants: Optimal caspase substrates are not necessarily optimal inhibitors
12. The head involution defective gene of Drosophila melanogaster functions in programmed cell death
13. Inhibition of interleukin 1-beta-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP
14. A cloning method to identify caspases and their regulators in yeast: Identification of Drosophila IAP1 as an inhibitor of the Drosophila caspase DCP-1
15. Drosophila homologs of baculovirus inhibitor of apoptosis proteins function to block cell death
16. Bcl-x-I interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
17. Inhibition of death receptor signals by cellular FLIP
18. A two-dimensional gel database of human colon carcinoma proteins
19. The Drosophila inhibitor of apoptosis D-IAP1 suppresses cell death induced by the caspase drICE
20. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
21. Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1
22. Application of capillary reversed-phase high-performance liquid chromatography to high-sensitivity protein sequence analysis
23. S-pyridylethylation of intact polacrylamide gels and in situ digestion of electrophoretically separated proteins: A rapid mass spectrometric method for identifying cysteine-containing peptides
24. FLICE, a novel FADD-homologous ICE/Ced-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex
25. Caspase-9, Bcl-x-I, and Apaf-1 form a ternary complex
26. Capillary column chromatography improves sample preparation for mass spectrometric analysis: Complete characterisation of human α-enolase from two-dimensional gels following in situ proteolytic digestion
27. Proposal for a common nomenclature for sequence ions in mass spectra of peptides
28. The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral-inhibitor of apoptosis proteins
29. Baculovirus inhibitors of apoptosis (IAPs) block activation of sf-caspase-1
30. Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
31. Cell death in development
32. The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID
33. Genetic control of programmed cell death in Drosophila
34. Apaf-1, a human protein homologous to C. elegans Ced-4, participates in cytochrome c-dependent activation of caspase-3